Effect of Treating Parents Colonized With Staphylococcus aureus on Transmission to Neonates in the Intensive Care Unit: A Randomized Clinical Trial

RCT (236 neonates) found that fewer neonates whose parents were treated with intranasal mupirocin acquired concordant S aureus colonisation vs those with parents given placebo (14.6% vs 28.7%, -14.1%, HR 0.43, 95% CI 0.16-0.79). Skin reaction rates were similar (4.8% vs 6.2%).
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news

Related Links:

Source: Infection - Category: Infectious Diseases Source Type: research
Authors: Min HJ, Min SJ, Kang H, Kim KS Abstract Purpose: Exercise modifies airway immune responses and susceptibility to infection. We investigated the effects of exercise on two HSPs (heat shock proteins), quantifying expression levels in nasal mucosa of both professional competitive athletes and non-athletes for comparison. Method: We used western blot technique to determine expression levels of HSPs in primary human nasal epithelial cells (HNECs). Nasal lavage (NAL) fluids were collected from 12 male professional volley ball players and 6 healthy males pre-submaximal exercise (running for 30 min at 70-80% of ma...
Source: International Journal of Medical Sciences - Category: Biomedical Science Tags: Int J Med Sci Source Type: research
The objectives of this study were the green synthesis of bismuth oxide nanoparticles using aqueous extract with a good potential for UV blocking and antibacterial activity. Based on the obtained results, Bi2O3 NPs can have a good candidate for different applications.
Source: Iranian Journal of Pharmaceutical Research - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 26 March 2020Source: Microbial PathogenesisAuthor(s): J. Vaughn, R.D. Abdi, B.E. Gillespie, O.Kerro Dego
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
Publication date: Available online 25 March 2020Source: Microbial PathogenesisAuthor(s): Siyu Yang, Wanyu Li, Zhaowei Fan, Lu Zhai, Jing Chen, Xue Xiao, Jun Ma, Baifen Song, Jinzhu Ma, Chunyu Tong, Liquan Yu, Yongzhong Yu, Weifan Cao, Yudong Cui
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
Molecules, Vol. 25, Pages 1518: N-Pyrazinoyl Substituted Amino Acids as Potential Antimycobacterial Agents—The Synthesis and Biological Evaluation of Enantiomers Molecules doi: 10.3390/molecules25071518 Authors: Martin Juhás Lucie Kučerová Ondřej Horáček Ondřej Janďourek Vladimír Kubíček Klára Konečná Radim Kučera Pavel Bárta Jiří Janoušek Pavla Paterová Jiří Kuneš Martin Doležal Jan Zitko Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis (Mtb), each year causi...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
New J. Chem., 2020, Accepted Manuscript DOI: 10.1039/C9NJ05748J, Paperzong-juan lian, Tian-Yang Lin, Caixia Yao, Yilong Su, Sheng-Mei Wu, Shenghua Liao Semiconductor nanocrystals copper indium sulfide CuInS2 (CIS) have the qualities of low toxicity, high absorption coefficient and near-infrared luminescence, which make them gain growing attentions due to their wide prospective... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - New J. Chem. latest articles - Category: Chemistry Authors: Source Type: research
Abstract The study is aimed to synthesize potent metal oxide based biomimetic nanocomposites to overcome the risk associated with artificial bone tissue engineering. High purity TiO2 nanoparticles are synthesized via hydrothermal route. A biomimetic nanocomposite scaffolds containing chitosan-sodium alginate (4: 4) blended with three different (0.5, 1, and 1.5 wt%) concentrations of hydrothermally synthesized TiO2 nanoparticles are obtained by solvent casting technique. The physico-chemical and thermal degradation properties of as-synthesized TiO2 nanoparticles and their nanocomposite scaffolds are analyzed. ...
Source: Appl Human Sci - Category: Physiology Authors: Tags: Mater Sci Eng C Mater Biol Appl Source Type: research
Staphylococcus aureus is a primary pathogen of orthopedic infections. By mediating antimicrobial resistance, S. aureus biofilm plays an important role in the recalcitrance of orthopedic infections, especially for...
Source: Annals of Clinical Microbiology and Antimicrobials - Category: Microbiology Authors: Tags: Research Source Type: research
Planta Med DOI: 10.1055/a-1130-4856Recently, the isolation and elucidation of a series of polyhydroxyanthraquinones were reported from an organic extract of a solid phase culture of an endophytic fungus, Penicillium restrictum (strain G85). One of these compounds, ω-hydroxyemodin (1), showed promising quorum-sensing inhibition against clinical isolates of methicillin-resistant Staphylococcus aureus (MRSA) in both in vitro and in vivo models. The initial supply of 1 was 19 mg, and this amount needed to be scaled by a factor of 30 to 50 times, in order to generate material for further in vivo studies. To do so, ...
Source: Planta Medica - Category: Drugs & Pharmacology Authors: Tags: Original Papers Source Type: research
More News: Clinical Trials | Health | Intensive Care | Mupirocin | Skin | Staphylococcus Aureus