Results of trial to stem hospital-acquired bacterial infections published

(NIH/National Institute of Allergy and Infectious Diseases) A trial evaluated whether daily bathing with the antiseptic soap chlorhexidine (CHG) -- and in those patients with MRSA, adding the nasal antibiotic mupirocin -- more effectively reduced hospital-acquired bacterial infections than bathing with ordinary soap and water. The researchers found that one subset of patients -- those with medical devices -- experienced a substantial benefit if they received the CHG/mupirocin intervention.
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news

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This study evaluates the relationship of PA to outcomes after open ventral hernia repair (OVHR).MethodsA prospective institutional database was queried for patients undergoing OVHR. Demographics, operative characteristics, and outcomes were evaluated by the reported PA and the administration of beta-lactam prophylaxis (BLP).ResultsAllergy histories were reviewed in 1178 patients. PA was reported in 21.6% of patients, with 55.5% reporting rash or hives, 15.0% airway compromise or anaphylaxis, and 29.5% no specific reaction. BLP was administered to 76.3% of patients, including 22.1% of PA patients and 89.9% of patients witho...
Source: Surgical Endoscopy - Category: Surgery Source Type: research
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Conclusion: In the process of the induction of «respiratory explosion» with MRSA strains related to MSSAthe activities of NADPH-oxidase is risen, which characterizes the level of monocyte and neutrophil granulocyte cytotoxicity as sufficient, in which case cellular activities of phagocytes are lowered.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Allergy and immunology Source Type: research
Conclusion: PMBL improves the clinical course of SAR in school-aged children. However, this effect has not been shown to be related to the ability of PMBL to decolonize MRSA from the nose.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Paediatric asthma and allergy Source Type: research
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ConclusionsAn antibiotic allergy label was associated with significantly higher rates of MRSA colonization but no statistical difference with VRE colonization.
Source: American Journal of Infection Control - Category: Infectious Diseases Source Type: research
We present a 23-year-old male with a history of cystic fibrosis (CF) with associated renal disease, bronchiectasis, pneumothorax, and distal intestinal obstruction syndrome admitted for CF exacerbation. Sputum culture was positive for methicillin resistant Staphylococcus aureus (MRSA). Chest imaging revealed extensive opacities in the left lung. His FEV1 during admission was 52% (baseline 70%). Allergy was consulted as inhaled vancomycin therapy was preferred, but the patient had previous vancomycin-induced reactions.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Source Type: research
ConclusionThis study concludes that twice ‐daily 16.5% MH augmented with 1.3 mg/mL MGO sinonasal rinses alone for 14 days is safe but not superior to culture‐directed oral antibiotics and twice‐daily saline rinses.
Source: International Forum of Allergy and Rhinology - Category: Allergy & Immunology Authors: Tags: ORIGINAL ARTICLE Source Type: research
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