Postdischarge Decolonization Plan Lowers MRSA Risk (CME/CE)

(MedPage Today) -- At-home protocol involved chlorhexidine mouthwash, chlorhexidine baths or showers, and nasal mupirocin
Source: MedPage Today Public Health - Category: American Health Source Type: news

Related Links:

MRSA has been reported as the main pathogen involved in osteomyelitis and prosthetic joint infections. The host/pathogen interaction is dynamic and requires several changes to promote bacterial survival. Here, we focused on the internalization and persistence behavior ofStaphylococcus aureus invasive strains belonging to the major MRSA clones, within human MG ‐63 osteoblasts. We used imaging flow cytometry, a technique able to analyze living host cells. We demonstrated that the intracellular persistence process is different among clones and depends on the total number of infected cells instead of the number of intracellu...
Source: MicrobiologyOpen - Category: Microbiology Authors: Tags: ORIGINAL ARTICLE Source Type: research
Incidence of and risk factors for chronic lung allograft dysfunction (CLAD) in lung transplantation for cystic fibrosis (CF) are not established. Methicillin resistant staphylococcus aureus (MRSA) is associated with CF morbidity but its association with CLAD is unclear. We aimed to describe CLAD incidence and assess if pre-transplant MRSA colonization is associated with CLAD.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: (756) Source Type: research
ConclusionsThe recommendations provided in this document are intended to assist the clinician in optimizing vancomycin for the treatment of invasive MRSA infections in adult and pediatric patients. An AUC/MIC by broth microdilution (BMD) ratio of 400 to 600 (assuming MICBMD of 1 mg/L) should be advocated as the target to achieve clinical efficacy while improving patient safety for patients with serious MRSA infections. In such cases, AUC ‐guided dosing and monitoring is the most accurate and optimal way to manage vancomycin therapy.
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - Category: Drugs & Pharmacology Authors: Tags: Special Article Source Type: research
When Vanessa is asked to clean up after patients who have the seasonal flu or measles or MRSA in the Pennsylvania hospital where she works in environmental services, she knows what to do. She knows how to disinfect surfaces, what needs to be thrown away and what she should wear to protect herself. But when she’s asked to clean rooms occupied by COVID-19 patients, she’s flying blind. “It’s kind of terrifying,” says Vanessa, who TIME is identifying by first name only for professional protection. Her supervisors told her to clean the rooms just as she would for a flu patient, but she says she&rsq...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 Source Type: news
ConclusionsThe recommendations provided in this document are intended to assist the clinician in optimizing vancomycin for the treatment of invasive MRSA infections in adult and pediatric patients. An AUC/MIC by broth microdilution (BMD) ratio of 400 to 600 (assuming MICBMD of 1 mg/L) should be advocated as the target to achieve clinical efficacy while improving patient safety for patients with serious MRSA infections. In such cases, AUC ‐guided dosing and monitoring is the most accurate and optimal way to manage vancomycin therapy.
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - Category: Drugs & Pharmacology Authors: Tags: Special Article Source Type: research
To evaluate nasal carriage, antibiotic susceptibility and molecular characteristics of methicillin-resistant Staphylococcus aureus (MRSA), as well as the risk factors of MRSA colonization, in human immunodeficien...
Source: BMC Infectious Diseases - Category: Infectious Diseases Authors: Tags: Research article Source Type: research
This cohort study evaluates the association of persistent Staphylococcus aureus colonization and household environmental contamination with recurrent skin and soft tissue infection in households with children with community-associated methicillin-resistant S aureus (MRSA) skin and soft tissue infection.
Source: JAMA Pediatrics - Category: Pediatrics Source Type: research
This study was conducted to determine the frequency of S. aureus nasal carriage in hemodialysis patients (HD) and health-care workers (HCW) at the main dialysis center of Bam city, located in southeast of Iran. In this cross-sectional study, a total of 52 nasal swabs were obtained from health-care workers and hemodialysis patients to detect methicillin-sensitive S. aureus (MSSA) isolates. The resistance to different antibacterial agents was determined by disk diffusion method. Also, Panton-Valentine Leukocidin (PVL) - encoding gene as well as Staphylococcal protein A (spa) type were determined. The nasal carriage rate of S...
Source: Pathogens and Global Health - Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research
ConclusionFree floating thrombus of the carotid arteries can be managed with stenting.
Source: Clinical Neuroradiology - Category: Neurology Source Type: research
Abstract Polyketide-terpenoid hybrid compounds are one of the largest families of meroterpenoids, with great potential for drug development for resistant pathogens. Genome sequence analysis of secondary metabolite gene clusters of a phytopathogenic fungus, Bipolaris sorokiniana 11134, revealed a type I polyketide gene cluster, consisting of highly reducing polyketide synthase, non-reducing polyketide synthase, and adjacent prenyltransferase. MS- and UV-guided isolations led to the isolation of ten meroterpenoids, including two new compounds: 19-dehydroxyl-3-epi-arthripenoid A (1) and 12-keto-cochlioquinone A (2). ...
Source: Applied Microbiology and Biotechnology - Category: Microbiology Authors: Tags: Appl Microbiol Biotechnol Source Type: research
More News: American Health | Chlorhexidine | Infectious Diseases | International Medicine & Public Health | MRSA | Mupirocin | Superbugs