Antiseptics Work Equally Well in Preventing Infection After Surgery for Open Fractures
WEDNESDAY, Nov. 2, 2022 -- Both 10 percent povidone-iodine and aqueous 4 percent chlorhexidine gluconate are equally effective for preventing postsurgical infections among patients requiring surgery for open fractures, according to a study published... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - November 2, 2022 Category: Pharmaceuticals Source Type: news

Local interventions for the management of alveolar osteitis (dry socket)
Cochrane Database Syst Rev . 2022 Sep 26;9(9):CD006968. doi: 10.1002/14651858.CD006968. Abstract Background: Alveolar osteitis (dry socket) is a complication of dental extractions more often involving mandibular molar teeth. It is associated with severe pain developing 2 to 3 days postoperatively with or without halitosis, a socket that may be partially or totally devoid of a blood clot, and increased postoperative visits. This is an update of the Cochrane Review first published in 2012. OBJECTIVES: To assess the effects of local interventions used for the prevention and treatment of alveolar osteitis (dry socket) followin...
Source: Dental Technology Blog - October 24, 2022 Category: Dentistry Source Type: news

How to improve aseptic technique to reduce bloodstream infection during vascular access procedures
The objectives of this roundtable of experts were to achieve a consensus on how to improve skin antisepsis in hospital, improve training, competency, compliance and consistency in skin antisepsis, review the role of devices in improving skin antisepsis, identify methods to improve skin antisepsis integrated with the Aseptic Non Touch Technique (ANTT ® ) approach, and identify challenges to the implementation of the panel ' s recommendations. Recommendations include using MHRA-licensed 2% chlorhexidine gluconate in 70% isopropyl alcohol solution with bidirectional strokes for up to 30 seconds, then leaving the skin to air ...
Source: Current Awareness Service for Health (CASH) - September 30, 2022 Category: Consumer Health News Source Type: news

Evaluating the effectiveness of octenidine-containing wash mitts in reducing infections in intensive care
This article explores the use of octenidine-containing single-use wash mitts in ICUs, which have been positively evaluated regarding antimicrobial activity, and ease and effectiveness of use. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - September 27, 2022 Category: Consumer Health News Source Type: news

Chlorhexidine (di)gluconate locking device for central line infection prevention in intensive care unit patients: a multi-unit, pilot randomized controlled trial
Conclusions: Using a device that delivers CHG into CVADs was feasible in the ICU. Findings from this trial will inform a full-scale randomized controlled trial and provide preliminary data on the effectiveness of CHGLS. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - September 20, 2022 Category: Consumer Health News Source Type: news

Evaluation of chlorhexidine sensitization amongst healthcare workers.
Conclusions: The prevalence figures for chlorhexidine sensitization in this study are higher than have been estimated previously for similar HCW cohorts. Increased exposure to chlorhexidine-based hand hygiene products was not demonstrated to increase sensitization in this group. Given the risk of severe reactions in sensitized individuals, this study indicates that evaluation of chlorhexidine allergy is important when investigating occupational allergy in HCWs. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - August 16, 2022 Category: Consumer Health News Source Type: news

Periogard (Chlorhexidine Gluconate Oral Rinse) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - July 25, 2022 Category: Drugs & Pharmacology Source Type: news

Evaluation of chlorhexidine sensitization amongst healthcare workers
Conclusions: The prevalence figures for chlorhexidine sensitization in this study are higher than have been estimated previously for similar HCW cohorts. Increased exposure to chlorhexidine-based hand hygiene products was not demonstrated to increase sensitization in this group. Given the risk of severe reactions in sensitized individuals, this study indicates that evaluation of chlorhexidine allergy is important when investigating occupational allergy in HCWs. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - July 20, 2022 Category: Consumer Health News Source Type: news

Paroex (Chlorhexidine Gluconate Oral Rinse) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - July 19, 2022 Category: Drugs & Pharmacology Source Type: news

Dyna-Hex 2 (Chlorhexidine Gluconate Liquid) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - May 23, 2022 Category: Drugs & Pharmacology Source Type: news

Increasing usage of chlorhexidine in health care settings: blessing or curse? A narrative review of the risk of chlorhexidine resistance and the implications for infection prevention and control
This study reviewed the published data regarding the evidence of reduced CHG susceptibility, the cross-resistance with antibiotics, and the implications for infection control for S. aureus, coagulase-negative staphylococci, E. coli, K. pneumoniae, and P. aeruginosa. Despite incongruity in definitions of " resistance, " 12 increased CHG minimal inhibitory values of these pathogens have been described, and different mutations encoding for CHG efflux pumps have been identified. Clinical relevance of species with reduced susceptibility to CHG is debatable and cross-resistance with antibiotics remains controversial. However, so...
Source: Current Awareness Service for Health (CASH) - May 17, 2022 Category: Consumer Health News Source Type: news

Increasing usage of chlorhexidine in health care settings: blessing or curse? A narrative review of the risk of chlorhexidine resistance and the implications for infection prevention and control
This study reviewed the published data regarding the evidence of reduced CHG susceptibility, the cross-resistance with antibiotics, and the implications for infection control for S. aureus, coagulase-negative staphylococci, E. coli, K. pneumoniae, and P. aeruginosa. Despite incongruity in definitions of " resistance, " increased CHG minimal inhibitory values of these pathogens have been described, and different mutations encoding for CHG efflux pumps have been identified. Clinical relevance of species with reduced susceptibility to CHG is debatable and cross-resistance with antibiotics remains controversial. However, some ...
Source: Current Awareness Service for Health (CASH) - March 21, 2022 Category: Consumer Health News Source Type: news

Antiplaque and antigingivitis efficacy of medicated and non-medicated sugar-free chewing gum as adjuncts to toothbrushing: systematic review and network meta-analysis
ConclusionSFCG containing GT+Xyl showed better antiplaque effect over negative controls. However, cautious interpretation is required due to the low number of direct comparisons arms. These shortcomings underscore the need for RCTs with mostly head-to-head comparison that provide more conclusive evidence.Clinical relevanceThere is no robust evidence for the clinical indications of sugar-free chewing gums as adjunct to toothbrushing for the control of biofilm or the treatment of gingivitis. (Source: Dental Technology Blog)
Source: Dental Technology Blog - January 28, 2022 Category: Dentistry Source Type: news

Sports mouthguards: Contamination, roughness, and chlorhexidine for disinfection - A randomized clinical trial
 Braz Dent J. Nov-Dec 2021;32(6):66-73.doi: 10.1590/0103-6440202104533.AbstractThe aim of the present in vivo study was to evaluate the bacterial contamination of sports mouthguards, surface roughness, and the efficacy of chlorhexidine gluconate spray in the disinfection of these devices. A randomized, blinded cross-over clinical trial was performed with twenty 9 to 13 years old children who practiced martial arts and participated in all phases of the study. They were instructed to wear mouthguards 3 alternated days a week for 1 hour and, after use, to spray sterile tap water or chlorhexidine 0.12%. The mouthguar...
Source: Dental Technology Blog - January 21, 2022 Category: Dentistry Source Type: news

Effects of Hand Hygiene Using 4% Chlorhexidine Gluconate or Natural Soap During Hand Rubbing Followed by Alcohol-Based 1% Chlorhexidine Gluconate Sanitizer Lotion in the Operating Room
Objective: Hand hygiene using either 4% chlorhexidine gluconate (CHG) or natural soap during hand rubbing, followed by alcohol-based 1% CHG sanitizer lotion in the operating room was compared to assess bacterial reduction, skin moisture, skin texture, and hand hygiene using qualitative questionnaires. Approach: A crossover study with 36 professional scrub nurses at two medical centers was performed to compare 4% CHG followed by alcohol-based 1% CHG sanitizer lotion, the Two-stage method with handwashing using natural soap followed by alcohol-based 1% CHG sanitizer lotion, and the Waterless method, after a period of 10 days...
Source: Current Awareness Service for Health (CASH) - January 17, 2022 Category: Consumer Health News Source Type: news