p21^{Waf1/CIP1} is a poor diagnostic and prognostic marker for OSCC although its expression increases in patients with N1 regional metastasis.
CONCLUSION: quantitative determination of p21<formula>^{Waf1/CIP1}</formula> standardizes and facilitates its analysis. Although its expression increases in patients with N1 regional metastasis, the loss of p21<formula>^{WAF1/CIP1}</formula> does not seem to have any relationship with the clinical and pathological variables of the tumors.
PMID: 25524938 [PubMed - in process] (Source: Cancer Biomarkers : Section A of Disease Markers)
Source: Cancer Biomarkers : Section A of Disease Markers - December 23, 2014 Category: Cancer & Oncology Authors: Pérez-Sayáns M, Suárez-Peñaranda JM, Iruegas EP, de Almeida MR, Barros-Angueira F, Torreira MG, García-García A Tags: Cancer Biomark Source Type: research
"Pictures Don't Lie, Seeing Is Believing": Exploring Attitudes to the Introduction of Pictorial Warnings on Cigarette Packs in Ghana
Conclusions:
Warning labels combining pictures and text have the potential to reduce smoking uptake, increase quit attempts, and reduce smoking appeal among smokers and nonsmokers in Ghana. Measures to prevent single stick sales, or to promote health messages to purchasers of single sticks, are required. (Source: Nicotine and Tobacco Research)
Source: Nicotine and Tobacco Research - November 24, 2014 Category: Addiction Authors: Singh, A., Owusu-Dabo, E., Britton, J., Munafo, M. R., Jones, L. L. Tags: Original Investigation Source Type: research
Benefits of an intraoral stent in decreasing the irradiation dose to oral healthy tissue: dosimetric and clinical features
Conclusions A stent was effective in decreasing doses to healthy structures and delaying the emergence of mucositis. (Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology)
Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology - November 6, 2014 Category: ENT & OMF Source Type: research
Mouth cancer awareness and beliefs among dental patients
ConclusionAwareness about oral cancer among Jordanian dental outpatients is low. These dental patients, especially those in high‐risk groups for mouth cancer and those of lower socio‐economic status (SES), are less well informed about the signs and risk factors of oral cancer. Interventions to improve public knowledge about oral cancer and attitudes towards early diagnosis and treatment are urgently indicated. (Source: International Dental Journal)
Source: International Dental Journal - November 5, 2014 Category: Dentistry Authors: Yazan Hassona, Crispian Scully, Mais Abu Ghosh, Zaid Khoury, Shadi Jarrar, Faleh Sawair Tags: Original Article Source Type: research
Speech and Swallowing Outcomes for Patients following Wide Local Excision and Sentinel Node Biopsy for Oral Cancer
This study measures speech and swallow outcome following wide local excision (WLE) and SNB. (Source: The British Journal of Oral and Maxillofacial Surgery)
Source: The British Journal of Oral and Maxillofacial Surgery - September 4, 2014 Category: ENT & OMF Authors: Sarah Siddiqui, Divya Sharma, Clare Schilling, Mark McGurk Tags: Abstracts Source Type: research
Cancers of the Tongue and Floor of Mouth: Five Year File Audit within the Acute Phase.
Conclusion: This is the first published study to report a relationship between function and dosage of clinical SLP intervention with this population. This is also the first known study to audit comprehensive functional outcomes in the acute phase of recovery with an Australian cohort. The findings contribute to establishing evidence based SLP practice with this population.
PMID: 25089517 [PubMed - as supplied by publisher] (Source: American Journal of Speech-Language Pathology)
Source: American Journal of Speech-Language Pathology - August 4, 2014 Category: Speech Therapy Authors: Blyth KM, McCabe P, Heard R, Clark J, Madill C, Ballard KJ Tags: Am J Speech Lang Pathol Source Type: research
Mouth cancer
Cancer of the mouth is the largest category of head and neck cancers and occurs in men more than women. Most patients are over age 50 years, but more than 10% of cases are diagnosed in younger individuals. In fact, there has been a significant increase in the number of cases among patients younger than age 45 years in the past 20 years. The two main factors associated with cancer in the mouth are tobacco and alcohol, but some cancers, particularly those found in the back of the mouth, are associated with exposure to human papillomavirus (HPV). Patients treated for mouth cancer are experiencing increasing quality of life, b...
Source: Dental Abstracts - July 1, 2014 Category: Dentistry Tags: Oral Cancer Source Type: research
Incidence and risk factors for colorectal neoplasia in patients with oral squamous cell carcinoma
ConclusionThe prevalence of advanced colorectal neoplasia is unexpectedly high in oral cancer patients. It should be recognised as a second primary tumour of oral cancer. Screening of oral cancer patients by colonoscopy should be routine practice, particularly among smokers and patients with a high intake of alcohol and floor of the mouth cancer.This article is protected by copyright. All rights reserved. (Source: Colorectal Disease)
Source: Colorectal Disease - July 1, 2014 Category: Gastroenterology Authors: H. Kishikawa, K. Sato, T. Yamauchi, A. Katakura, T. Shibahara, N. Takano, J. Nishida Tags: Original Article Source Type: research
Mouth cancer
Cancer of the mouth is the largest category of head and neck cancers and occurs in men more than women. Most patients are over age 50 years, but more than 10% of cases are diagnosed in younger individuals. In fact, there has been a significant increase in the number of cases among patients younger than age 45 years in the past 20 years. The two main factors associated with cancer in the mouth are tobacco and alcohol, but some cancers, particularly those found in the back of the mouth, are associated with exposure to human papillomavirus (HPV). (Source: Dental Abstracts)
Source: Dental Abstracts - July 1, 2014 Category: Dentistry Tags: Oral Cancer Source Type: research
Iodine-125 brachytherapy in the management of squamous cell carcinoma of the oral cavity and oropharynx
Conclusions: 125I can be used as the sole treatment or as a boost to external beam radiotherapy, with or without surgery for early mouth cancer. It combines the radiobiological advantages of LDR brachytherapy with minimum staff exposure. It is a flexible system. Local control is excellent with acceptable morbidity, and the treatment time is short. (Source: Brachytherapy)
Source: Brachytherapy - May 12, 2014 Category: Cancer & Oncology Authors: Clare Stannard, Gerrie Maree, Susan Tovey, Alistair Hunter, Julie Wetter Source Type: research
Dosimetric And Clinical Analysis of Intraoral Stent in Patients With Oral Cancer Undergoing Radiation Therapy
Conclusion: The use of intraoral stents was effective in decreasing radiation doses to healthy structures and had no impact on mucositis severity. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - January 21, 2014 Category: ENT & OMF Authors: JULIANA ROCHA VERRONE, GRAZIELLA CHAGAS JAGUAR, MARIA APARECIDA CONTE MAIA, ALESSANDRA DAS DORES MARCICANO, PETRUS PAULO COMBÁS EUFRAZIO DA SILVA, JÓSE DIVALDO PRADO, FÁBIO DE ABREU ALVES Tags: Online Only Articles Source Type: research
Osteoradionecrosis Management With Low-Level Laser Therapy Support
Osteoradionecrosis of the jaw (ORNJ) is a side effect of radiotherapy given to treat mouth cancer. The association between decreasing bone repair and local trauma and/or infection facilitates ORNJ and may lead to mandibular fracture, resulting in morbidity. Man, 62, experienced extensive ORNJ with an extraoral active fistula. After bacterial cultivation in a bone fragment, the antibiotic chosen was ciprofloxacin. Treatment consisted of bone debridement, 808-nm low-level laser therapy, and photodynamic therapy with a 660-nm laser in the exposed intraoral bone and fistulous path. After a year, ORNJ was stable and caused no p...
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - January 21, 2014 Category: ENT & OMF Authors: MARIANA COMPAROTTO MINAMISAKO, LILIANE JANETE GRANDO, MARIA INÊS MEURER, YASMIN GUTERRES, THAÍSE CRISTINA GEREMIAS, CARLOS EDUARDO CHRZANOWSKI PEREIRA DE SOUZA, CARLA GIRARDI Tags: Online Only Articles Source Type: research
Effect of Mouth Cancer Awareness Week on urgent suspected head and neck cancer referrals
Abstract: The purpose of this study was to find out whether Mouth Cancer Awareness Week and associated activities made any difference to the number of urgent or two-week urgent referrals to the oral and maxillofacial department at University Hospital, Aintree, whether they were appropriate, and the number of patients who were found to have cancer. A prospective audit over six months before, during, and after the awareness week showed a rise in the number of referrals over time, with the highest number in February. Of the 120 patients evaluated, cancer was confirmed in 13 (11%). (Source: The British Journal of Oral and Maxillofacial Surgery)
Source: The British Journal of Oral and Maxillofacial Surgery - July 9, 2012 Category: ENT & OMF Authors: Raheela Rafiq, Paul Brocklehurst, Simon N. Rogers Tags: Short Communications Source Type: research
