Plant-derived immuno-adjuvants in vaccines formulation: a promising avenue for improving vaccines efficacy against SARS-CoV-2 virus
Pharmacol Rep. 2022 Sep 20. doi: 10.1007/s43440-022-00418-4. Online ahead of print.ABSTRACTThe SARS-CoV-2 outbreak has posed a plethora of problems for the global healthcare system and socioeconomic burden. Despite valiant efforts to contain the COVID-19 outbreak, the situation has deteriorated to the point that there are no viable preventive therapies to treat this disease. The case count has skyrocketed globally due to the newly evolved variants. Despite vaccination drives, the re-occurrence of recent pandemic waves has reinforced the importance of innovation/utilization of immune-booster to achieve appropriate long-term...
Source: Pharmacological Reports - September 20, 2022 Category: Drugs & Pharmacology Authors: Arbind Kumar Aashish Sharma Narendra Vijay Tirpude Yogendra Padwad Vipin Hallan Sanjay Kumar Source Type: research

The Argentine mistletoes Ligaria cuneifolia (Ruiz & amp; Pav.) Tiegh (Loranthaceae) and Phoradendron liga (Gillies ex Hook. & amp; Arn.) Eichler (Santalaceae). Thirty years of research
Chem Biodivers. 2022 Sep 1. doi: 10.1002/cbdv.202200565. Online ahead of print.ABSTRACTLigaria cuneifolia (Ruiz & Pav.) Tiegh (Loranthaceae) and Phoradendron liga (Gillies ex Hook. & Arn.) Eichler (Santalaceae) are regarded as Argentine mistletoes based on their similarities with the European counterpart, Viscum album L. (Santalaceae). These two species are the most used medicinal plants to treat high blood pressure in the Argentinian population. To provide scientific grounds to their traditional use and therapeutic potential, they were selected as herbal drug candidates. The main findings would support the anti-hy...
Source: Chemistry and Biodiversity - September 1, 2022 Category: Biochemistry Authors: Cecilia Beatriz Dobrecky Silvia E Lucangioli Marcelo L Wagner Source Type: research

In-Vitro Growth Kinetics of Mesenchymal Stem Cells in Cytotoxicity Tests Using Low-Diluted Viscum Album
CONCLUSION: The results suggest that the use of efficient methods to assess the in-vitro cytotoxicity of VA-based homeopathic medicines using MSC lineages may predict the potential action at different concentrations. These findings demonstrated that VAD1D2 interferes with canine MSC growth kinetics.PMID:35988582 | DOI:10.1055/s-0042-1747682 (Source: Homeopathy)
Source: Homeopathy - August 21, 2022 Category: Complementary Medicine Authors: Ana Catarina Viana Valle Hilana Dos Santos Sena Brunel Bruno St éfano Lima Dallago Lucas Santana Rodrigues Patr ícia Furtado Malard Rosiane Andrade da Costa Rafael Rossetto Ros ângela Vieira de Andrade Source Type: research

In-Vitro Growth Kinetics of Mesenchymal Stem Cells in Cytotoxicity Tests Using Low-Diluted Viscum Album
CONCLUSION: The results suggest that the use of efficient methods to assess the in-vitro cytotoxicity of VA-based homeopathic medicines using MSC lineages may predict the potential action at different concentrations. These findings demonstrated that VAD1D2 interferes with canine MSC growth kinetics.PMID:35988582 | DOI:10.1055/s-0042-1747682 (Source: Homeopathy)
Source: Homeopathy - August 21, 2022 Category: Complementary Medicine Authors: Ana Catarina Viana Valle Hilana Dos Santos Sena Brunel Bruno St éfano Lima Dallago Lucas Santana Rodrigues Patr ícia Furtado Malard Rosiane Andrade da Costa Rafael Rossetto Ros ângela Vieira de Andrade Source Type: research

In-Vitro Growth Kinetics of Mesenchymal Stem Cells in Cytotoxicity Tests Using Low-Diluted Viscum Album
CONCLUSION: The results suggest that the use of efficient methods to assess the in-vitro cytotoxicity of VA-based homeopathic medicines using MSC lineages may predict the potential action at different concentrations. These findings demonstrated that VAD1D2 interferes with canine MSC growth kinetics.PMID:35988582 | DOI:10.1055/s-0042-1747682 (Source: Homeopathy)
Source: Homeopathy - August 21, 2022 Category: Complementary Medicine Authors: Ana Catarina Viana Valle Hilana Dos Santos Sena Brunel Bruno St éfano Lima Dallago Lucas Santana Rodrigues Patr ícia Furtado Malard Rosiane Andrade da Costa Rafael Rossetto Ros ângela Vieira de Andrade Source Type: research

In-Vitro Growth Kinetics of Mesenchymal Stem Cells in Cytotoxicity Tests Using Low-Diluted Viscum Album
CONCLUSION: The results suggest that the use of efficient methods to assess the in-vitro cytotoxicity of VA-based homeopathic medicines using MSC lineages may predict the potential action at different concentrations. These findings demonstrated that VAD1D2 interferes with canine MSC growth kinetics.PMID:35988582 | DOI:10.1055/s-0042-1747682 (Source: Homeopathy)
Source: Homeopathy - August 21, 2022 Category: Complementary Medicine Authors: Ana Catarina Viana Valle Hilana Dos Santos Sena Brunel Bruno St éfano Lima Dallago Lucas Santana Rodrigues Patr ícia Furtado Malard Rosiane Andrade da Costa Rafael Rossetto Ros ângela Vieira de Andrade Source Type: research

In-Vitro Growth Kinetics of Mesenchymal Stem Cells in Cytotoxicity Tests Using Low-Diluted Viscum Album
CONCLUSION: The results suggest that the use of efficient methods to assess the in-vitro cytotoxicity of VA-based homeopathic medicines using MSC lineages may predict the potential action at different concentrations. These findings demonstrated that VAD1D2 interferes with canine MSC growth kinetics.PMID:35988582 | DOI:10.1055/s-0042-1747682 (Source: Homeopathy)
Source: Homeopathy - August 21, 2022 Category: Complementary Medicine Authors: Ana Catarina Viana Valle Hilana Dos Santos Sena Brunel Bruno St éfano Lima Dallago Lucas Santana Rodrigues Patr ícia Furtado Malard Rosiane Andrade da Costa Rafael Rossetto Ros ângela Vieira de Andrade Source Type: research

In-Vitro Growth Kinetics of Mesenchymal Stem Cells in Cytotoxicity Tests Using Low-Diluted Viscum Album
CONCLUSION: The results suggest that the use of efficient methods to assess the in-vitro cytotoxicity of VA-based homeopathic medicines using MSC lineages may predict the potential action at different concentrations. These findings demonstrated that VAD1D2 interferes with canine MSC growth kinetics.PMID:35988582 | DOI:10.1055/s-0042-1747682 (Source: Homeopathy)
Source: Homeopathy - August 21, 2022 Category: Complementary Medicine Authors: Ana Catarina Viana Valle Hilana Dos Santos Sena Brunel Bruno St éfano Lima Dallago Lucas Santana Rodrigues Patr ícia Furtado Malard Rosiane Andrade da Costa Rafael Rossetto Ros ângela Vieira de Andrade Source Type: research

In-Vitro Growth Kinetics of Mesenchymal Stem Cells in Cytotoxicity Tests Using Low-Diluted Viscum Album
CONCLUSION: The results suggest that the use of efficient methods to assess the in-vitro cytotoxicity of VA-based homeopathic medicines using MSC lineages may predict the potential action at different concentrations. These findings demonstrated that VAD1D2 interferes with canine MSC growth kinetics.PMID:35988582 | DOI:10.1055/s-0042-1747682 (Source: Homeopathy)
Source: Homeopathy - August 21, 2022 Category: Complementary Medicine Authors: Ana Catarina Viana Valle Hilana Dos Santos Sena Brunel Bruno St éfano Lima Dallago Lucas Santana Rodrigues Patr ícia Furtado Malard Rosiane Andrade da Costa Rafael Rossetto Ros ângela Vieira de Andrade Source Type: research

In-Vitro Growth Kinetics of Mesenchymal Stem Cells in Cytotoxicity Tests Using Low-Diluted Viscum Album
CONCLUSION: The results suggest that the use of efficient methods to assess the in-vitro cytotoxicity of VA-based homeopathic medicines using MSC lineages may predict the potential action at different concentrations. These findings demonstrated that VAD1D2 interferes with canine MSC growth kinetics.PMID:35988582 | DOI:10.1055/s-0042-1747682 (Source: Homeopathy)
Source: Homeopathy - August 21, 2022 Category: Complementary Medicine Authors: Ana Catarina Viana Valle Hilana Dos Santos Sena Brunel Bruno St éfano Lima Dallago Lucas Santana Rodrigues Patr ícia Furtado Malard Rosiane Andrade da Costa Rafael Rossetto Ros ângela Vieira de Andrade Source Type: research

In-Vitro Growth Kinetics of Mesenchymal Stem Cells in Cytotoxicity Tests Using Low-Diluted Viscum Album
CONCLUSION: The results suggest that the use of efficient methods to assess the in-vitro cytotoxicity of VA-based homeopathic medicines using MSC lineages may predict the potential action at different concentrations. These findings demonstrated that VAD1D2 interferes with canine MSC growth kinetics.PMID:35988582 | DOI:10.1055/s-0042-1747682 (Source: Homeopathy)
Source: Homeopathy - August 21, 2022 Category: Complementary Medicine Authors: Ana Catarina Viana Valle Hilana Dos Santos Sena Brunel Bruno St éfano Lima Dallago Lucas Santana Rodrigues Patr ícia Furtado Malard Rosiane Andrade da Costa Rafael Rossetto Ros ângela Vieira de Andrade Source Type: research

Plant lectin: A promising future anti-tumor drug
Biochimie. 2022 Aug 8:S0300-9084(22)00197-3. doi: 10.1016/j.biochi.2022.08.002. Online ahead of print.ABSTRACTSince the early discovery of plant lectins at the end of the 19th century, and the finding that they could agglutinate erythrocytes and precipitate glycans from their solutions, many applications and biological roles have been described for these proteins. Later, the observed erythrocytes clumping features were attributed to the lectin-cell surface glycoconjugates recognition. Neoplastic transformation leads to various cellular alterations which impact the growth of the cell and its persistence, among which is the ...
Source: Biochimie - August 11, 2022 Category: Biochemistry Authors: Emadeldin Hassan E Konozy Makarim El-Fadil M Osman Source Type: research

Plant lectin: A promising future anti-tumor drug
Biochimie. 2022 Aug 8:S0300-9084(22)00197-3. doi: 10.1016/j.biochi.2022.08.002. Online ahead of print.ABSTRACTSince the early discovery of plant lectins at the end of the 19th century, and the finding that they could agglutinate erythrocytes and precipitate glycans from their solutions, many applications and biological roles have been described for these proteins. Later, the observed erythrocytes clumping features were attributed to the lectin-cell surface glycoconjugates recognition. Neoplastic transformation leads to various cellular alterations which impact the growth of the cell and its persistence, among which is the ...
Source: Biochimie - August 11, 2022 Category: Biochemistry Authors: Emadeldin Hassan E Konozy Makarim El-Fadil M Osman Source Type: research

Plant lectin: A promising future anti-tumor drug
Biochimie. 2022 Aug 8:S0300-9084(22)00197-3. doi: 10.1016/j.biochi.2022.08.002. Online ahead of print.ABSTRACTSince the early discovery of plant lectins at the end of the 19th century, and the finding that they could agglutinate erythrocytes and precipitate glycans from their solutions, many applications and biological roles have been described for these proteins. Later, the observed erythrocytes clumping features were attributed to the lectin-cell surface glycoconjugates recognition. Neoplastic transformation leads to various cellular alterations which impact the growth of the cell and its persistence, among which is the ...
Source: Biochimie - August 11, 2022 Category: Biochemistry Authors: Emadeldin Hassan E Konozy Makarim El-Fadil M Osman Source Type: research

Genes, Vol. 13, Pages 1173: Transcriptome Profiling of a Common Mistletoe Species Parasitizing Four Typical Host Species in Urban Southwest China
In this study, the transcriptomes of T. nigrans individuals parasitizing four typical host species (Broussonetia papyrifera [Bpap] a broad-leaved tree species; Cryptomeria fortunei [Cfor] a coniferous tree species; Cinnamomum septentrionale [Csep] an evergreen tree species; and Ginkgo biloba [Gbil] a deciduous-coniferous tree species) were sequenced, and the expression profiles and metabolic pathways compared among hosts. A total of 40.06 Gb of clean sequence data were generated in nine cDNA libraries. These were de novo assembled into 293,823 transcripts with an N50 value of 1790 bp. A large number of differentially expre...
Source: Genes - June 29, 2022 Category: Genetics & Stem Cells Authors: Jingge Kuang Yufei Wang Kangshan Mao Richard Milne Mingcheng Wang Ning Miao Tags: Article Source Type: research