Heterogeneity of health-related quality of life after mild traumatic brain injury with systemic injury: a cluster analytic approach
CONCLUSION: These findings suggest more than 50% of hospitalised individuals with mTBI and systemic injury, have reduced HRQoL, 10 weeks after mTBI. Pain and fatigue warrant clinical attention in these individuals.IMPLICATIONS FOR REHABILITATIONMild traumatic brain injury is a common event that has been shown to be associated with persistently reduced health-related quality of life in approximately 50% of individuals 6 to 12 months after injury.Health-related quality of life likely varies between individuals after injuryRelative to the "normal" population, most individuals in this cohort of individuals with mTBI and system...
Source: Disability and Rehabilitation - April 24, 2024 Category: Rehabilitation Authors: Jacqueline F I Anderson Source Type: research
Exploring the Two-Way Link Between Migraines and Venous Thromboembolism: A Bidirectional Two-Sample Mendelian Randomization Study
CONCLUSION: The findings of this Mendelian Randomization assessment provide substantiation for a reciprocal causative association between migraine and VTE within the European population.PMID:38657649 | DOI:10.1055/a-2313-0311 (Source: Thrombosis and Haemostasis)
Source: Thrombosis and Haemostasis - April 24, 2024 Category: Hematology Authors: Yang Wang Xiaofang Hu Xiaoqing Wang Lili Li Peng Lou Zhaoxuan Liu Source Type: research
Dihydroergotamine mesylate nasal spray: an acute treatment option for migraine in adults
Expert Rev Neurother. 2024 Apr 24:1-10. doi: 10.1080/14737175.2024.2342446. Online ahead of print.ABSTRACTINTRODUCTION: Although the landscape of migraine symptomatic treatment has been enriched by novel effective drugs, it is mandatory to critically reappraise older molecules to ascertain whether they could still represent reliable alternatives in specific endophenotypes of patients or migraine attacks. Among these, dihydroergotamine (DHE) nasal spray has been shown to be effective and is characterized by greater tolerability and manageability than the parenteral DHE formulation.AREAS COVERED: In this narrative review, th...
Source: Expert Review of Neurotherapeutics - April 24, 2024 Category: Neurology Authors: Marcello Silvestro Ilaria Orologio Alessandro Tessitore Francesca Trojsi Gioacchino Tedeschi Antonio Russo Source Type: research
