Effect of the Intralesional Forms of Methylprednisolone Acetate and Methotrexate on Psoriatic Nails
Skinmed. 2024 Mar 18;22(1):35-39. eCollection 2024.ABSTRACTIndividuals with psoriatic nails often have a lower quality of life relative to their counterparts with healthy nails. Methotrexate (MTX), an anti-neoplastic agent, is a longstanding treatment option for nail psoriasis. In the current study, we compared the effects of MTX to that of a corticosteroid, namely, methylprednisolone acetate (i.e., Depo-Medrol®) across individuals with nail psoriasis. We used a cohort study design, and both agents were administered intralesionally. Outcome variables were based on the Nail Psoriasis Severity Index (NAPSI). We quantified t...
Source: Skinmed - March 18, 2024 Category: Dermatology Authors: Riad Kassem Aditya K Gupta Mary A Bamimore Mesbah Talukder Avner Shemer Lee Magal Anna Lyakhovitsky Ralph Daniel Baruch Kaplan Eran Galili Source Type: research
Effect of the Intralesional Forms of Methylprednisolone Acetate and Methotrexate on Psoriatic Nails
Skinmed. 2024 Mar 18;22(1):35-39. eCollection 2024.ABSTRACTIndividuals with psoriatic nails often have a lower quality of life relative to their counterparts with healthy nails. Methotrexate (MTX), an anti-neoplastic agent, is a longstanding treatment option for nail psoriasis. In the current study, we compared the effects of MTX to that of a corticosteroid, namely, methylprednisolone acetate (i.e., Depo-Medrol®) across individuals with nail psoriasis. We used a cohort study design, and both agents were administered intralesionally. Outcome variables were based on the Nail Psoriasis Severity Index (NAPSI). We quantified t...
Source: Skinmed - March 18, 2024 Category: Dermatology Authors: Riad Kassem Aditya K Gupta Mary A Bamimore Mesbah Talukder Avner Shemer Lee Magal Anna Lyakhovitsky Ralph Daniel Baruch Kaplan Eran Galili Source Type: research
Effect of the Intralesional Forms of Methylprednisolone Acetate and Methotrexate on Psoriatic Nails
Skinmed. 2024 Mar 18;22(1):35-39. eCollection 2024.ABSTRACTIndividuals with psoriatic nails often have a lower quality of life relative to their counterparts with healthy nails. Methotrexate (MTX), an anti-neoplastic agent, is a longstanding treatment option for nail psoriasis. In the current study, we compared the effects of MTX to that of a corticosteroid, namely, methylprednisolone acetate (i.e., Depo-Medrol®) across individuals with nail psoriasis. We used a cohort study design, and both agents were administered intralesionally. Outcome variables were based on the Nail Psoriasis Severity Index (NAPSI). We quantified t...
Source: Skinmed - March 18, 2024 Category: Dermatology Authors: Riad Kassem Aditya K Gupta Mary A Bamimore Mesbah Talukder Avner Shemer Lee Magal Anna Lyakhovitsky Ralph Daniel Baruch Kaplan Eran Galili Source Type: research
Effect of the Intralesional Forms of Methylprednisolone Acetate and Methotrexate on Psoriatic Nails
Skinmed. 2024 Mar 18;22(1):35-39. eCollection 2024.ABSTRACTIndividuals with psoriatic nails often have a lower quality of life relative to their counterparts with healthy nails. Methotrexate (MTX), an anti-neoplastic agent, is a longstanding treatment option for nail psoriasis. In the current study, we compared the effects of MTX to that of a corticosteroid, namely, methylprednisolone acetate (i.e., Depo-Medrol®) across individuals with nail psoriasis. We used a cohort study design, and both agents were administered intralesionally. Outcome variables were based on the Nail Psoriasis Severity Index (NAPSI). We quantified t...
Source: Skinmed - March 18, 2024 Category: Dermatology Authors: Riad Kassem Aditya K Gupta Mary A Bamimore Mesbah Talukder Avner Shemer Lee Magal Anna Lyakhovitsky Ralph Daniel Baruch Kaplan Eran Galili Source Type: research
Effect of the Intralesional Forms of Methylprednisolone Acetate and Methotrexate on Psoriatic Nails
Skinmed. 2024 Mar 18;22(1):35-39. eCollection 2024.ABSTRACTIndividuals with psoriatic nails often have a lower quality of life relative to their counterparts with healthy nails. Methotrexate (MTX), an anti-neoplastic agent, is a longstanding treatment option for nail psoriasis. In the current study, we compared the effects of MTX to that of a corticosteroid, namely, methylprednisolone acetate (i.e., Depo-Medrol®) across individuals with nail psoriasis. We used a cohort study design, and both agents were administered intralesionally. Outcome variables were based on the Nail Psoriasis Severity Index (NAPSI). We quantified t...
Source: Skinmed - March 18, 2024 Category: Dermatology Authors: Riad Kassem Aditya K Gupta Mary A Bamimore Mesbah Talukder Avner Shemer Lee Magal Anna Lyakhovitsky Ralph Daniel Baruch Kaplan Eran Galili Source Type: research
Tonsillectomy combined with intravenous methylprednisolone pulse for Japanese children with severe IgA vasculitis with nephritis —authors’ reply
(Source: Pediatric Nephrology)
Source: Pediatric Nephrology - March 15, 2024 Category: Urology & Nephrology Source Type: research
Initial treatment with tonsillectomy combined with intravenous methylprednisolone pulse — another option for Japanese children with severe nephrotic IgA vasculitis with nephritis
(Source: Pediatric Nephrology)
Source: Pediatric Nephrology - March 15, 2024 Category: Urology & Nephrology Source Type: research
Global tuberculosis disease and infection in systemic lupus erythematosus patients: A systematic review and meta-analysis
CONCLUSION: TB prevalence in SLE was relatively high and associated with GC. Awareness of TB and lowering GC dose are warranted to alleviate the TB burden in SLE.PMID:38490946 | DOI:10.1177/09612033241239504 (Source: Lupus)
Source: Lupus - March 15, 2024 Category: Rheumatology Authors: Guntur Darmawan Lie Monica Sherine Liman Suryo Anggoro Kusumo Wibowo Laniyati Hamijoyo Lika Apriani Nur Atik Bachti Alisjahbana Edhyana Sahiratmadja Source Type: research
Global tuberculosis disease and infection in systemic lupus erythematosus patients: A systematic review and meta-analysis
CONCLUSION: TB prevalence in SLE was relatively high and associated with GC. Awareness of TB and lowering GC dose are warranted to alleviate the TB burden in SLE.PMID:38490946 | DOI:10.1177/09612033241239504 (Source: Lupus)
Source: Lupus - March 15, 2024 Category: Rheumatology Authors: Guntur Darmawan Lie Monica Sherine Liman Suryo Anggoro Kusumo Wibowo Laniyati Hamijoyo Lika Apriani Nur Atik Bachti Alisjahbana Edhyana Sahiratmadja Source Type: research
Downstaging Hepatocellular Carcinoma with Checkpoint Inhibitor Therapy Improves Access to Curative Liver Transplant
ConclusionWe describe nine patients with HCC outside Milan with inadequate response with liver-directed therapy, who achieved marked responses with CPIT, allowing for consideration of successful liver transplantation. Our case series supports the consideration of locoregional therapies and CPIT for downstaging to within transplant criteria. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - March 14, 2024 Category: Cancer & Oncology Source Type: research
Recurrent Tolosa-Hunt syndrome: a case report
CONCLUSION: Tolosa-Hunt syndrome is a syndrome of painful ophthalmoplegia which responds well to steroid therapy but has a tendency to recur. Hence, patients must be adequately informed about the reoccurrence and kept under follow-up.PMID:38463132 | PMC:PMC10923349 | DOI:10.1097/MS9.0000000000001745 (Source: Annals of Medicine)
Source: Annals of Medicine - March 11, 2024 Category: Internal Medicine Authors: Shashank Neupane Prasamsa Pudasaini Bishal Dhakal Pasang Sherpa Pooja Rokaya Anukul Subedi Source Type: research
Probable secondary hemophagocytic lymphohistiocytosis manifesting as central nervous system lesions after COVID-19 vaccination: a case report
ConclusionTo date, 23 cases of COVID-19 vaccine-related HLH have been reported. Additionally, HLH in COVID-19 patients has been reported in various case reports. To the best of our knowledge, this is the first reported case of central nervous system involvement in HLH related to any type of COVID-19 vaccine. This case suggests that even when there are no systemic symptoms after COVID-19 vaccination, HLH should be considered as a differential diagnosis if brain lesions are suggestive of CNS demyelinating disease. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - March 11, 2024 Category: Neurology Source Type: research
Clinical manifestations and outcomes in tubulointerstitial nephritis and uveitis syndrome: a case report and a systematic review in China
ConclusionTINU syndrome is prone to misdiagnosis because kidney damage may not occur simultaneously with uveitis. The incidence of kidney sequelae in children is lower than that in adults, and glucocorticoids are the preferred treatment.INPLASY registration number INPLASY202350050. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - March 9, 2024 Category: Urology & Nephrology Source Type: research
Case Report: Minocycline-induced drug reaction with eosinophilia and systemic symptoms syndrome: a case report and literature review
In conclusion, we reported a rare minocycline-induced DRESS syndrome who developed fever, eosinophilia, acute rash, pharyngitis, lymphadenopathy, acute kidney injury, hepatitis, and splenomegaly. Our report provides detailed clinical features of minocycline-induced DRESS syndrome, which helps us further understand this severe adverse event. (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - March 7, 2024 Category: Drugs & Pharmacology Source Type: research
