Retrospective study on long-term effects of hormone replacement therapy (HRT) and iron chelation therapy on glucose homeostasis and insulin secretion in female ß- thalassemia major (β-TM) patients with acquired hypogonadotropic- hypogonadism (AHH)
CONCLUSION: Deterioration of glycemia (dysglycemia) occurred in 45.4% (5/11) of thalassemic females on long-term HRT. Additional studies are needed to elucidate the validity of our preliminary observations.PMID:37539597 | DOI:10.23750/abm.v94i4.14631 (Source: Acta Bio-Medica : Atenei Parmensis)
Source: Acta Bio-Medica : Atenei Parmensis - August 4, 2023 Category: General Medicine Authors: Vincenzo De Sanctis Shahina Daar Ashraf Soliman Ploutarchos Tzoulis Salvatore Di Maio Christos Kattamis Source Type: research

Retrospective study on long-term effects of hormone replacement therapy (HRT) and iron chelation therapy on glucose homeostasis and insulin secretion in female ß- thalassemia major (β-TM) patients with acquired hypogonadotropic- hypogonadism (AHH)
CONCLUSION: Deterioration of glycemia (dysglycemia) occurred in 45.4% (5/11) of thalassemic females on long-term HRT. Additional studies are needed to elucidate the validity of our preliminary observations.PMID:37539597 | DOI:10.23750/abm.v94i4.14631 (Source: Acta Bio-Medica : Atenei Parmensis)
Source: Acta Bio-Medica : Atenei Parmensis - August 4, 2023 Category: General Medicine Authors: Vincenzo De Sanctis Shahina Daar Ashraf Soliman Ploutarchos Tzoulis Salvatore Di Maio Christos Kattamis Source Type: research

Retrospective study on long-term effects of hormone replacement therapy (HRT) and iron chelation therapy on glucose homeostasis and insulin secretion in female ß- thalassemia major (β-TM) patients with acquired hypogonadotropic- hypogonadism (AHH)
CONCLUSION: Deterioration of glycemia (dysglycemia) occurred in 45.4% (5/11) of thalassemic females on long-term HRT. Additional studies are needed to elucidate the validity of our preliminary observations.PMID:37539597 | DOI:10.23750/abm.v94i4.14631 (Source: Acta Bio-Medica : Atenei Parmensis)
Source: Acta Bio-Medica : Atenei Parmensis - August 4, 2023 Category: General Medicine Authors: Vincenzo De Sanctis Shahina Daar Ashraf Soliman Ploutarchos Tzoulis Salvatore Di Maio Christos Kattamis Source Type: research

Retrospective study on long-term effects of hormone replacement therapy (HRT) and iron chelation therapy on glucose homeostasis and insulin secretion in female ß- thalassemia major (β-TM) patients with acquired hypogonadotropic- hypogonadism (AHH)
CONCLUSION: Deterioration of glycemia (dysglycemia) occurred in 45.4% (5/11) of thalassemic females on long-term HRT. Additional studies are needed to elucidate the validity of our preliminary observations.PMID:37539597 | DOI:10.23750/abm.v94i4.14631 (Source: Acta Bio-Medica : Atenei Parmensis)
Source: Acta Bio-Medica : Atenei Parmensis - August 4, 2023 Category: General Medicine Authors: Vincenzo De Sanctis Shahina Daar Ashraf Soliman Ploutarchos Tzoulis Salvatore Di Maio Christos Kattamis Source Type: research

Retrospective study on long-term effects of hormone replacement therapy (HRT) and iron chelation therapy on glucose homeostasis and insulin secretion in female ß- thalassemia major (β-TM) patients with acquired hypogonadotropic- hypogonadism (AHH)
CONCLUSION: Deterioration of glycemia (dysglycemia) occurred in 45.4% (5/11) of thalassemic females on long-term HRT. Additional studies are needed to elucidate the validity of our preliminary observations.PMID:37539597 | DOI:10.23750/abm.v94i4.14631 (Source: Acta Bio-Medica : Atenei Parmensis)
Source: Acta Bio-Medica : Atenei Parmensis - August 4, 2023 Category: General Medicine Authors: Vincenzo De Sanctis Shahina Daar Ashraf Soliman Ploutarchos Tzoulis Salvatore Di Maio Christos Kattamis Source Type: research

Retrospective study on long-term effects of hormone replacement therapy (HRT) and iron chelation therapy on glucose homeostasis and insulin secretion in female ß- thalassemia major (β-TM) patients with acquired hypogonadotropic- hypogonadism (AHH)
CONCLUSION: Deterioration of glycemia (dysglycemia) occurred in 45.4% (5/11) of thalassemic females on long-term HRT. Additional studies are needed to elucidate the validity of our preliminary observations.PMID:37539597 | DOI:10.23750/abm.v94i4.14631 (Source: Acta Bio-Medica : Atenei Parmensis)
Source: Acta Bio-Medica : Atenei Parmensis - August 4, 2023 Category: General Medicine Authors: Vincenzo De Sanctis Shahina Daar Ashraf Soliman Ploutarchos Tzoulis Salvatore Di Maio Christos Kattamis Source Type: research

Retrospective study on long-term effects of hormone replacement therapy (HRT) and iron chelation therapy on glucose homeostasis and insulin secretion in female ß- thalassemia major (β-TM) patients with acquired hypogonadotropic- hypogonadism (AHH)
CONCLUSION: Deterioration of glycemia (dysglycemia) occurred in 45.4% (5/11) of thalassemic females on long-term HRT. Additional studies are needed to elucidate the validity of our preliminary observations.PMID:37539597 | DOI:10.23750/abm.v94i4.14631 (Source: Acta Bio-Medica : Atenei Parmensis)
Source: Acta Bio-Medica : Atenei Parmensis - August 4, 2023 Category: General Medicine Authors: Vincenzo De Sanctis Shahina Daar Ashraf Soliman Ploutarchos Tzoulis Salvatore Di Maio Christos Kattamis Source Type: research

Retrospective study on long-term effects of hormone replacement therapy (HRT) and iron chelation therapy on glucose homeostasis and insulin secretion in female ß- thalassemia major (β-TM) patients with acquired hypogonadotropic- hypogonadism (AHH)
CONCLUSION: Deterioration of glycemia (dysglycemia) occurred in 45.4% (5/11) of thalassemic females on long-term HRT. Additional studies are needed to elucidate the validity of our preliminary observations.PMID:37539597 | DOI:10.23750/abm.v94i4.14631 (Source: Acta Bio-Medica : Atenei Parmensis)
Source: Acta Bio-Medica : Atenei Parmensis - August 4, 2023 Category: General Medicine Authors: Vincenzo De Sanctis Shahina Daar Ashraf Soliman Ploutarchos Tzoulis Salvatore Di Maio Christos Kattamis Source Type: research

Retrospective study on long-term effects of hormone replacement therapy (HRT) and iron chelation therapy on glucose homeostasis and insulin secretion in female ß- thalassemia major (β-TM) patients with acquired hypogonadotropic- hypogonadism (AHH)
CONCLUSION: Deterioration of glycemia (dysglycemia) occurred in 45.4% (5/11) of thalassemic females on long-term HRT. Additional studies are needed to elucidate the validity of our preliminary observations.PMID:37539597 | DOI:10.23750/abm.v94i4.14631 (Source: Acta Bio-Medica : Atenei Parmensis)
Source: Acta Bio-Medica : Atenei Parmensis - August 4, 2023 Category: General Medicine Authors: Vincenzo De Sanctis Shahina Daar Ashraf Soliman Ploutarchos Tzoulis Salvatore Di Maio Christos Kattamis Source Type: research

Retrospective study on long-term effects of hormone replacement therapy (HRT) and iron chelation therapy on glucose homeostasis and insulin secretion in female ß- thalassemia major (β-TM) patients with acquired hypogonadotropic- hypogonadism (AHH)
CONCLUSION: Deterioration of glycemia (dysglycemia) occurred in 45.4% (5/11) of thalassemic females on long-term HRT. Additional studies are needed to elucidate the validity of our preliminary observations.PMID:37539597 | DOI:10.23750/abm.v94i4.14631 (Source: Acta Bio-Medica : Atenei Parmensis)
Source: Acta Bio-Medica : Atenei Parmensis - August 4, 2023 Category: General Medicine Authors: Vincenzo De Sanctis Shahina Daar Ashraf Soliman Ploutarchos Tzoulis Salvatore Di Maio Christos Kattamis Source Type: research

Retrospective study on long-term effects of hormone replacement therapy (HRT) and iron chelation therapy on glucose homeostasis and insulin secretion in female ß- thalassemia major (β-TM) patients with acquired hypogonadotropic- hypogonadism (AHH)
CONCLUSION: Deterioration of glycemia (dysglycemia) occurred in 45.4% (5/11) of thalassemic females on long-term HRT. Additional studies are needed to elucidate the validity of our preliminary observations.PMID:37539597 | DOI:10.23750/abm.v94i4.14631 (Source: Acta Bio-Medica : Atenei Parmensis)
Source: Acta Bio-Medica : Atenei Parmensis - August 4, 2023 Category: General Medicine Authors: Vincenzo De Sanctis Shahina Daar Ashraf Soliman Ploutarchos Tzoulis Salvatore Di Maio Christos Kattamis Source Type: research

Retrospective study on long-term effects of hormone replacement therapy (HRT) and iron chelation therapy on glucose homeostasis and insulin secretion in female ß- thalassemia major (β-TM) patients with acquired hypogonadotropic- hypogonadism (AHH)
CONCLUSION: Deterioration of glycemia (dysglycemia) occurred in 45.4% (5/11) of thalassemic females on long-term HRT. Additional studies are needed to elucidate the validity of our preliminary observations.PMID:37539597 | PMC:PMC10440782 | DOI:10.23750/abm.v94i4.14631 (Source: Acta Bio-Medica : Atenei Parmensis)
Source: Acta Bio-Medica : Atenei Parmensis - August 4, 2023 Category: General Medicine Authors: Vincenzo De Sanctis Shahina Daar Ashraf Soliman Ploutarchos Tzoulis Salvatore Di Maio Christos Kattamis Source Type: research

Development and validation of an expanded panel of progestins using liquid chromatography-tandem triple quadrupole mass spectrometry (LC-MS/MS) to monitor protocol compliance in hormonal contraceptive pharmacokinetic/pharmacodynamic studies
We developed and validated use of ultra-high performance liquid chromatography-heated electrospray ionization-tandem triple quadrupole mass spectrometry (LC-MS/MS) to simultaneously analyze serum concentrations of ethinylestradiol (EE), dienogest (DNG), norelgestromin (NGMN), norethindrone (NET), gestodene (GSD), levonorgestrel (LNG), etonogestrel (ENG), segesterone acetate (NES), medroxyprogesterone acetate (MPA), and drospirenone (DRSP). The calibration range for all targets was 0.009 to 10 ng/ml, with lower limit of quantification of 0.009 ng/ml for all analytes except GSD (0.019 ng/ml). (Source: Contraception)
Source: Contraception - July 25, 2023 Category: OBGYN Authors: Jeffrey T. Jensen, Bethany T. Waites, Emily R. Boniface, Sara McCrimmon, Steven Blue, David W. Erikson Source Type: research

Comparison of cumulative live birth rates between progestin and GnRH analogues in preimplantation genetic testing cycles
CONCLUSIONS: PPOS regimen may be adversely affect cumulative LBR and blastocyst quality in women with good prognosis compared to GnRH analogues in PGT cycles.PMID:37450562 | DOI:10.1210/clinem/dgad397 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - July 14, 2023 Category: Endocrinology Authors: Ruiqiong Zhou Mei Dong Li Huang Songlu Wang Zhaoyi Wang Liqing Xu Xiqian Zhang Fenghua Liu Source Type: research

Comparison of cumulative live birth rates between progestin and GnRH analogues in preimplantation genetic testing cycles
CONCLUSIONS: PPOS regimen may be adversely affect cumulative LBR and blastocyst quality in women with good prognosis compared to GnRH analogues in PGT cycles.PMID:37450562 | DOI:10.1210/clinem/dgad397 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - July 14, 2023 Category: Endocrinology Authors: Ruiqiong Zhou Mei Dong Li Huang Songlu Wang Zhaoyi Wang Liqing Xu Xiqian Zhang Fenghua Liu Source Type: research