Cytomegalovirus durably primes neutrophil oxidative burst
J Leukoc Biol. 2023 Aug 12:qiad091. doi: 10.1093/jleuko/qiad091. Online ahead of print.ABSTRACTCytomegalovirus (CMV) is a ubiquitous herpes virus that infects most humans, thereafter persisting lifelong in tissues of the host. It is a known pathogen in immunosuppressed patients, but its impact on immunocompetent hosts remains less understood. Recent data have shown that CMV leaves a significant and long lasting imprint in host immunity that may confer some protection against subsequent bacterial infection. Such innate immune activation may come at a cost, however, with potential to cause immunopathology. Neutrophils are ce...
Source: Herpes - August 11, 2023 Category: Infectious Diseases Authors: Thomas F Marandu Michael Dombek Michael Gutknecht Marion Griessl Ingred Goretti Ri ça Barbora Vlkov á Krist ína Macáková Eleni Panagioti Alec Griffith James Lederer Michael Yaffe Sidharth Shankar Leo Otterbein Kiyoshi Itagaki Carl J Hauser Charles H Source Type: research
Cytomegalovirus durably primes neutrophil oxidative burst
J Leukoc Biol. 2023 Aug 12:qiad091. doi: 10.1093/jleuko/qiad091. Online ahead of print.ABSTRACTCytomegalovirus (CMV) is a ubiquitous herpes virus that infects most humans, thereafter persisting lifelong in tissues of the host. It is a known pathogen in immunosuppressed patients, but its impact on immunocompetent hosts remains less understood. Recent data have shown that CMV leaves a significant and long lasting imprint in host immunity that may confer some protection against subsequent bacterial infection. Such innate immune activation may come at a cost, however, with potential to cause immunopathology. Neutrophils are ce...
Source: Journal of Leukocyte Biology - August 11, 2023 Category: Hematology Authors: Thomas F Marandu Michael Dombek Michael Gutknecht Marion Griessl Ingred Goretti Ri ça Barbora Vlkov á Krist ína Macáková Eleni Panagioti Alec Griffith James Lederer Michael Yaffe Sidharth Shankar Leo Otterbein Kiyoshi Itagaki Carl J Hauser Charles H Source Type: research
Cytomegalovirus durably primes neutrophil oxidative burst
J Leukoc Biol. 2023 Aug 12:qiad091. doi: 10.1093/jleuko/qiad091. Online ahead of print.ABSTRACTCytomegalovirus (CMV) is a ubiquitous herpes virus that infects most humans, thereafter persisting lifelong in tissues of the host. It is a known pathogen in immunosuppressed patients, but its impact on immunocompetent hosts remains less understood. Recent data have shown that CMV leaves a significant and long lasting imprint in host immunity that may confer some protection against subsequent bacterial infection. Such innate immune activation may come at a cost, however, with potential to cause immunopathology. Neutrophils are ce...
Source: Journal of Leukocyte Biology - August 11, 2023 Category: Hematology Authors: Thomas F Marandu Michael Dombek Michael Gutknecht Marion Griessl Ingred Goretti Ri ça Barbora Vlkov á Krist ína Macáková Eleni Panagioti Alec Griffith James Lederer Michael Yaffe Sidharth Shankar Leo Otterbein Kiyoshi Itagaki Carl J Hauser Charles H Source Type: research
Cytomegalovirus durably primes neutrophil oxidative burst
J Leukoc Biol. 2023 Aug 12:qiad091. doi: 10.1093/jleuko/qiad091. Online ahead of print.ABSTRACTCytomegalovirus (CMV) is a ubiquitous herpes virus that infects most humans, thereafter persisting lifelong in tissues of the host. It is a known pathogen in immunosuppressed patients, but its impact on immunocompetent hosts remains less understood. Recent data have shown that CMV leaves a significant and long lasting imprint in host immunity that may confer some protection against subsequent bacterial infection. Such innate immune activation may come at a cost, however, with potential to cause immunopathology. Neutrophils are ce...
Source: Journal of Leukocyte Biology - August 11, 2023 Category: Hematology Authors: Thomas F Marandu Michael Dombek Michael Gutknecht Marion Griessl Ingred Goretti Ri ça Barbora Vlkov á Krist ína Macáková Eleni Panagioti Alec Griffith James Lederer Michael Yaffe Sidharth Shankar Leo Otterbein Kiyoshi Itagaki Carl J Hauser Charles H Source Type: research
Cytomegalovirus durably primes neutrophil oxidative burst
J Leukoc Biol. 2023 Aug 12:qiad091. doi: 10.1093/jleuko/qiad091. Online ahead of print.ABSTRACTCytomegalovirus (CMV) is a ubiquitous herpes virus that infects most humans, thereafter persisting lifelong in tissues of the host. It is a known pathogen in immunosuppressed patients, but its impact on immunocompetent hosts remains less understood. Recent data have shown that CMV leaves a significant and long lasting imprint in host immunity that may confer some protection against subsequent bacterial infection. Such innate immune activation may come at a cost, however, with potential to cause immunopathology. Neutrophils are ce...
Source: Journal of Leukocyte Biology - August 11, 2023 Category: Hematology Authors: Thomas F Marandu Michael Dombek Michael Gutknecht Marion Griessl Ingred Goretti Ri ça Barbora Vlkov á Krist ína Macáková Eleni Panagioti Alec Griffith James Lederer Michael Yaffe Sidharth Shankar Leo Otterbein Kiyoshi Itagaki Carl J Hauser Charles H Source Type: research
Vie Scope ® versus videolaryngoscopy in expected difficult airways: a randomized controlled trial
CONCLUSION: Visualization with the Vie Scope was noninferior to VL in patients with an anticipated difficult airway, but TTI was longer in the Vie Scope group.STUDY REGISTRATION: ClinicalTrials.gov (NCT05044416); registered 5 September 2021.PMID:37537324 | DOI:10.1007/s12630-023-02534-y (Source: Canadian Journal of Anaesthesia)
Source: Canadian Journal of Anaesthesia - August 3, 2023 Category: Anesthesiology Authors: Martin Petzoldt Catharina Gr ün Viktor A W ünsch Marcus Bauer Tim T Hardel J örn Grensemann Source Type: research
Vie Scope ® versus videolaryngoscopy in expected difficult airways: a randomized controlled trial
CONCLUSION: Visualization with the Vie Scope was noninferior to VL in patients with an anticipated difficult airway, but TTI was longer in the Vie Scope group.STUDY REGISTRATION: ClinicalTrials.gov (NCT05044416); registered 5 September 2021.PMID:37537324 | DOI:10.1007/s12630-023-02534-y (Source: Canadian Journal of Anaesthesia)
Source: Canadian Journal of Anaesthesia - August 3, 2023 Category: Anesthesiology Authors: Martin Petzoldt Catharina Gr ün Viktor A W ünsch Marcus Bauer Tim T Hardel J örn Grensemann Source Type: research
Vie Scope ® versus videolaryngoscopy in expected difficult airways: a randomized controlled trial
CONCLUSION: Visualization with the Vie Scope was noninferior to VL in patients with an anticipated difficult airway, but TTI was longer in the Vie Scope group.STUDY REGISTRATION: ClinicalTrials.gov (NCT05044416); registered 5 September 2021.PMID:37537324 | DOI:10.1007/s12630-023-02534-y (Source: Canadian Journal of Anaesthesia)
Source: Canadian Journal of Anaesthesia - August 3, 2023 Category: Anesthesiology Authors: Martin Petzoldt Catharina Gr ün Viktor A W ünsch Marcus Bauer Tim T Hardel J örn Grensemann Source Type: research
Vie Scope ® versus videolaryngoscopy in expected difficult airways: a randomized controlled trial
CONCLUSION: Visualization with the Vie Scope was noninferior to VL in patients with an anticipated difficult airway, but TTI was longer in the Vie Scope group.STUDY REGISTRATION: ClinicalTrials.gov (NCT05044416); registered 5 September 2021.PMID:37537324 | DOI:10.1007/s12630-023-02534-y (Source: Canadian Journal of Anaesthesia)
Source: Canadian Journal of Anaesthesia - August 3, 2023 Category: Anesthesiology Authors: Martin Petzoldt Catharina Gr ün Viktor A W ünsch Marcus Bauer Tim T Hardel J örn Grensemann Source Type: research
Vie Scope ® versus videolaryngoscopy in expected difficult airways: a randomized controlled trial
CONCLUSION: Visualization with the Vie Scope was noninferior to VL in patients with an anticipated difficult airway, but TTI was longer in the Vie Scope group.STUDY REGISTRATION: ClinicalTrials.gov (NCT05044416); registered 5 September 2021.PMID:37537324 | DOI:10.1007/s12630-023-02534-y (Source: Canadian Journal of Anaesthesia)
Source: Canadian Journal of Anaesthesia - August 3, 2023 Category: Anesthesiology Authors: Martin Petzoldt Catharina Gr ün Viktor A W ünsch Marcus Bauer Tim T Hardel J örn Grensemann Source Type: research
A multifaceted provider-centred intervention versus usual care to improve the recognition and diagnosis of depression in primary health care: a hybrid study
CONCLUSIONS: A multicomponent intervention for the implementation of a clinical guideline for the management of depression in primary care produced improvements in the identification of depression and in the degree of severity recorded.PMID:37427569 | DOI:10.1017/S1463423623000300 (Source: Primary Care)
Source: Primary Care - July 10, 2023 Category: Primary Care Authors: Eva Vanesa Nogueras Nazaret Cantero Mar ía Macías Jos é Miguel Morales-Asencio Jos é María García-Herrera Pérez-Bryan Mar ía M Hurtado Source Type: research
A multifaceted provider-centred intervention versus usual care to improve the recognition and diagnosis of depression in primary health care: a hybrid study
CONCLUSIONS: A multicomponent intervention for the implementation of a clinical guideline for the management of depression in primary care produced improvements in the identification of depression and in the degree of severity recorded.PMID:37427569 | DOI:10.1017/S1463423623000300 (Source: Primary Care)
Source: Primary Care - July 10, 2023 Category: Primary Care Authors: Eva Vanesa Nogueras Nazaret Cantero Mar ía Macías Jos é Miguel Morales-Asencio Jos é María García-Herrera Pérez-Bryan Mar ía M Hurtado Source Type: research
A multi-strain probiotic promoted recovery of puppies from gastroenteritis in a randomized, double-blind, placebo-controlled study
CONCLUSION: In a randomized, double-blind, placebo-controlled study, puppies with gastroenteritis symptoms receiving a multi-strain probiotic had rapid improvement, implying beneficial effects on the microbiota and its functionality.PMID:37397694 | PMC:PMC10286135 (Source: The Canadian Veterinary Journal)
Source: The Canadian Veterinary Journal - July 3, 2023 Category: Veterinary Research Authors: Rosa A Molina Marcela D'Urso Villar Mar ía H Miranda Natalia C Maldonado Graciela M Vignolo Mar ía E F Nader-Macías Source Type: research
A multi-strain probiotic promoted recovery of puppies from gastroenteritis in a randomized, double-blind, placebo-controlled study
CONCLUSION: In a randomized, double-blind, placebo-controlled study, puppies with gastroenteritis symptoms receiving a multi-strain probiotic had rapid improvement, implying beneficial effects on the microbiota and its functionality.PMID:37397694 | PMC:PMC10286135 (Source: The Canadian Veterinary Journal)
Source: The Canadian Veterinary Journal - July 3, 2023 Category: Veterinary Research Authors: Rosa A Molina Marcela D'Urso Villar Mar ía H Miranda Natalia C Maldonado Graciela M Vignolo Mar ía E F Nader-Macías Source Type: research
A multi-strain probiotic promoted recovery of puppies from gastroenteritis in a randomized, double-blind, placebo-controlled study
CONCLUSION: In a randomized, double-blind, placebo-controlled study, puppies with gastroenteritis symptoms receiving a multi-strain probiotic had rapid improvement, implying beneficial effects on the microbiota and its functionality.PMID:37397694 | PMC:PMC10286135 (Source: The Canadian Veterinary Journal)
Source: The Canadian Veterinary Journal - July 3, 2023 Category: Veterinary Research Authors: Rosa A Molina Marcela D'Urso Villar Mar ía H Miranda Natalia C Maldonado Graciela M Vignolo Mar ía E F Nader-Macías Source Type: research
