The effects of lycopene and tomato consumption on cardiovascular risk factors in adults: a Grade assessment systematic review and meta-analysis
CONCLUSION: Overall, the findings showed that lycopene and tomato consumption did not affect cardiovascular risk factors. However, lycopene supplementation may result in a significant improvement in MDA levels. With the view to confirming these results, further studies with long-term duration and different doses are needed.PMID:37496241 | DOI:10.2174/1381612829666230726112510 (Source: Current Pharmaceutical Design)
Source: Current Pharmaceutical Design - July 27, 2023 Category: Drugs & Pharmacology Authors: Mohammad Zamani Farimah Behmanesh Nia Kimia Ghaedi Saba Mohammadpour Niusha Amirani Kian Goudarzi Kosar Hosseini Matin Ghanavati Damoon Ashtary-Larky Source Type: research
Co ‐occurrence of Mycotoxin‐Induced Hepatotoxicity in Mice Inhibited by Lycopene: Mitochondrial Impairment and Early Hepatic Fibrosis
ConclusionLYC successfully attenuates early hepatic fibrosis mainly through antioxidant activities and prevented mitochondrial injury. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - July 24, 2023 Category: Food Science Authors: Jia Lin,
Tianzeng Liang,
Yang Huang,
Cuige Zuo,
Dan Wang,
Yulan Liu Tags: Research Article Source Type: research
Rapid construction of E.coli chassis with genome multi-position integration of isopentenol utilization pathway for efficient and stable terpenoid accumulation
This study aimed to construct IUP-employed E. coli chassis for stably synthesizing terpenoids. As to effectiveness, promotor engineering strategy was employed to regulate IUP expression level, while ribosome-binding site (RBS) library of the key enzyme was constructed for screening the optimal RBS, followed by optimization of concentration of inducer and substrates, the titer of reporting production, lycopene, from 0.087 to 8.67 mg/OD600 . As about stability, the IUP expression cassette was integrated into the genome through transposition tool based on CRISPR-associated transposases. Results showed that the strain with 13 ...
Source: Biotechnology Journal - July 21, 2023 Category: Biotechnology Authors: Yu-Zhou Wang Hong-Yan Jing Xin Li Feng Zhang Xiao-Man Sun Source Type: research
Rapid construction of E.coli chassis with genome multi-position integration of isopentenol utilization pathway for efficient and stable terpenoid accumulation
This study aimed to construct IUP-employed E. coli chassis for stably synthesizing terpenoids. As to effectiveness, promotor engineering strategy was employed to regulate IUP expression level, while ribosome-binding site (RBS) library of the key enzyme was constructed for screening the optimal RBS, followed by optimization of concentration of inducer and substrates, the titer of reporting production, lycopene, from 0.087 to 8.67 mg/OD600 . As about stability, the IUP expression cassette was integrated into the genome through transposition tool based on CRISPR-associated transposases. Results showed that the strain with 13 ...
Source: Biotechnology Journal - July 21, 2023 Category: Biotechnology Authors: Yu-Zhou Wang Hong-Yan Jing Xin Li Feng Zhang Xiao-Man Sun Source Type: research
Rapid construction of E.coli chassis with genome multi-position integration of isopentenol utilization pathway for efficient and stable terpenoid accumulation
This study aimed to construct IUP-employed E. coli chassis for stably synthesizing terpenoids. As to effectiveness, promotor engineering strategy was employed to regulate IUP expression level, while ribosome-binding site (RBS) library of the key enzyme was constructed for screening the optimal RBS, followed by optimization of concentration of inducer and substrates, the titer of reporting production, lycopene, from 0.087 to 8.67 mg/OD600 . As about stability, the IUP expression cassette was integrated into the genome through transposition tool based on CRISPR-associated transposases. Results showed that the strain with 13 ...
Source: Biotechnology Journal - July 21, 2023 Category: Biotechnology Authors: Yu-Zhou Wang Hong-Yan Jing Xin Li Feng Zhang Xiao-Man Sun Source Type: research
Rapid construction of E.coli chassis with genome multi-position integration of isopentenol utilization pathway for efficient and stable terpenoid accumulation
This study aimed to construct IUP-employed E. coli chassis for stably synthesizing terpenoids. As to effectiveness, promotor engineering strategy was employed to regulate IUP expression level, while ribosome-binding site (RBS) library of the key enzyme was constructed for screening the optimal RBS, followed by optimization of concentration of inducer and substrates, the titer of reporting production, lycopene, from 0.087 to 8.67 mg/OD600 . As about stability, the IUP expression cassette was integrated into the genome through transposition tool based on CRISPR-associated transposases. Results showed that the strain with 13 ...
Source: Biotechnology Journal - July 21, 2023 Category: Biotechnology Authors: Yu-Zhou Wang Hong-Yan Jing Xin Li Feng Zhang Xiao-Man Sun Source Type: research
A review of the chemistry and biological activities of natural colorants, dyes, and pigments: challenges, and opportunities for food, cosmetics, and pharmaceutical application
This article reviewed the chemistry and therapeutic potentials of over 570 colored molecules from plants, fungi, bacteria, insects, algae, and marine sources. Moreover, related biological activities, advanced extraction, and identification approaches were reviewed. A variety of biological activities, including cytotoxicity against cancer cells, antioxidant, anti-inflammatory, wound healing, anti-microbial, antiviral, and anti-protozoal activities, have been reported for different pigments. Considering their structural backbone, they were classified as naphthoquinones, carotenoids, flavonoids, xanthones, anthocyanins, benzo...
Source: Chemistry and Biodiversity - July 20, 2023 Category: Biochemistry Authors: Ardalan Pasdaran Maryam Zare Azar Hamedi Azadeh Hamedi Source Type: research
Lycopene enhances bone neoformation in calvaria bone defects of ovariectomized rats
Braz Dent J. 2023 May-Jun;34(3):50-56. doi: 10.1590/0103-6440202304980.ABSTRACTOsteoporosis can affect a significant part of the population and fractures are the most common complications associated with this disease, leading to high public health costs. Thus, the prevention of fractures is relevant to individuals with signs and symptoms as well as to the health system. Postmenopausal osteoporosis has been associated with oxidative stress, emphasizing the importance of an efficient defense system to maintain bone health. Lycopene is a carotenoid with antioxidant properties that may stimulate osteoblastogenesis and inhibit ...
Source: Braz Dent J - July 19, 2023 Category: Dentistry Authors: Vit ória Ricardo Luiz Gustavo de Sousa Isabela Hallak Regalo Dimitrius Leonardo Pitol Karina Fittipaldi Bombonato-Prado Simone Cecilio Hallak Regalo Selma Siessere Source Type: research
Lycopene enhances bone neoformation in calvaria bone defects of ovariectomized rats
Braz Dent J. 2023 May-Jun;34(3):50-56. doi: 10.1590/0103-6440202304980.ABSTRACTOsteoporosis can affect a significant part of the population and fractures are the most common complications associated with this disease, leading to high public health costs. Thus, the prevention of fractures is relevant to individuals with signs and symptoms as well as to the health system. Postmenopausal osteoporosis has been associated with oxidative stress, emphasizing the importance of an efficient defense system to maintain bone health. Lycopene is a carotenoid with antioxidant properties that may stimulate osteoblastogenesis and inhibit ...
Source: Braz Dent J - July 19, 2023 Category: Dentistry Authors: Vit ória Ricardo Luiz Gustavo de Sousa Isabela Hallak Regalo Dimitrius Leonardo Pitol Karina Fittipaldi Bombonato-Prado Simone Cecilio Hallak Regalo Selma Siessere Source Type: research
Lycopene enhances bone neoformation in calvaria bone defects of ovariectomized rats
Braz Dent J. 2023 May-Jun;34(3):50-56. doi: 10.1590/0103-6440202304980.ABSTRACTOsteoporosis can affect a significant part of the population and fractures are the most common complications associated with this disease, leading to high public health costs. Thus, the prevention of fractures is relevant to individuals with signs and symptoms as well as to the health system. Postmenopausal osteoporosis has been associated with oxidative stress, emphasizing the importance of an efficient defense system to maintain bone health. Lycopene is a carotenoid with antioxidant properties that may stimulate osteoblastogenesis and inhibit ...
Source: Braz Dent J - July 19, 2023 Category: Dentistry Authors: Vit ória Ricardo Luiz Gustavo de Sousa Isabela Hallak Regalo Dimitrius Leonardo Pitol Karina Fittipaldi Bombonato-Prado Simone Cecilio Hallak Regalo Selma Siessere Source Type: research
Lycopene enhances bone neoformation in calvaria bone defects of ovariectomized rats
Braz Dent J. 2023 May-Jun;34(3):50-56. doi: 10.1590/0103-6440202304980.ABSTRACTOsteoporosis can affect a significant part of the population and fractures are the most common complications associated with this disease, leading to high public health costs. Thus, the prevention of fractures is relevant to individuals with signs and symptoms as well as to the health system. Postmenopausal osteoporosis has been associated with oxidative stress, emphasizing the importance of an efficient defense system to maintain bone health. Lycopene is a carotenoid with antioxidant properties that may stimulate osteoblastogenesis and inhibit ...
Source: Braz Dent J - July 19, 2023 Category: Dentistry Authors: Vit ória Ricardo Luiz Gustavo de Sousa Isabela Hallak Regalo Dimitrius Leonardo Pitol Karina Fittipaldi Bombonato-Prado Simone Cecilio Hallak Regalo Selma Siessere Source Type: research
Lycopene enhances bone neoformation in calvaria bone defects of ovariectomized rats
Braz Dent J. 2023 May-Jun;34(3):50-56. doi: 10.1590/0103-6440202304980.ABSTRACTOsteoporosis can affect a significant part of the population and fractures are the most common complications associated with this disease, leading to high public health costs. Thus, the prevention of fractures is relevant to individuals with signs and symptoms as well as to the health system. Postmenopausal osteoporosis has been associated with oxidative stress, emphasizing the importance of an efficient defense system to maintain bone health. Lycopene is a carotenoid with antioxidant properties that may stimulate osteoblastogenesis and inhibit ...
Source: Braz Dent J - July 19, 2023 Category: Dentistry Authors: Vit ória Ricardo Luiz Gustavo de Sousa Isabela Hallak Regalo Dimitrius Leonardo Pitol Karina Fittipaldi Bombonato-Prado Simone Cecilio Hallak Regalo Selma Siessere Source Type: research
Lycopene enhances bone neoformation in calvaria bone defects of ovariectomized rats
Braz Dent J. 2023 May-Jun;34(3):50-56. doi: 10.1590/0103-6440202304980.ABSTRACTOsteoporosis can affect a significant part of the population and fractures are the most common complications associated with this disease, leading to high public health costs. Thus, the prevention of fractures is relevant to individuals with signs and symptoms as well as to the health system. Postmenopausal osteoporosis has been associated with oxidative stress, emphasizing the importance of an efficient defense system to maintain bone health. Lycopene is a carotenoid with antioxidant properties that may stimulate osteoblastogenesis and inhibit ...
Source: Braz Dent J - July 19, 2023 Category: Dentistry Authors: Vit ória Ricardo Luiz Gustavo de Sousa Isabela Hallak Regalo Dimitrius Leonardo Pitol Karina Fittipaldi Bombonato-Prado Simone Cecilio Hallak Regalo Selma Siessere Source Type: research
Lycopene enhances bone neoformation in calvaria bone defects of ovariectomized rats
Braz Dent J. 2023 May-Jun;34(3):50-56. doi: 10.1590/0103-6440202304980.ABSTRACTOsteoporosis can affect a significant part of the population and fractures are the most common complications associated with this disease, leading to high public health costs. Thus, the prevention of fractures is relevant to individuals with signs and symptoms as well as to the health system. Postmenopausal osteoporosis has been associated with oxidative stress, emphasizing the importance of an efficient defense system to maintain bone health. Lycopene is a carotenoid with antioxidant properties that may stimulate osteoblastogenesis and inhibit ...
Source: Braz Dent J - July 19, 2023 Category: Dentistry Authors: Vit ória Ricardo Luiz Gustavo de Sousa Isabela Hallak Regalo Dimitrius Leonardo Pitol Karina Fittipaldi Bombonato-Prado Simone Cecilio Hallak Regalo Selma Siessere Source Type: research
Lycopene enhances bone neoformation in calvaria bone defects of ovariectomized rats
Braz Dent J. 2023 May-Jun;34(3):50-56. doi: 10.1590/0103-6440202304980.ABSTRACTOsteoporosis can affect a significant part of the population and fractures are the most common complications associated with this disease, leading to high public health costs. Thus, the prevention of fractures is relevant to individuals with signs and symptoms as well as to the health system. Postmenopausal osteoporosis has been associated with oxidative stress, emphasizing the importance of an efficient defense system to maintain bone health. Lycopene is a carotenoid with antioxidant properties that may stimulate osteoblastogenesis and inhibit ...
Source: Braz Dent J - July 19, 2023 Category: Dentistry Authors: Vit ória Ricardo Luiz Gustavo de Sousa Isabela Hallak Regalo Dimitrius Leonardo Pitol Karina Fittipaldi Bombonato-Prado Simone Cecilio Hallak Regalo Selma Siessere Source Type: research
