Abstract S5-04: Low-fat dietary pattern and breast cancer overall survival in the women's health initiative dietary modification randomized controlled trial
Introduction: Among 48,835 postmenopausal women randomized in the Women's Health Initiative Dietary Modification (WHI DM) primary prevention trial, 1,767 women were diagnosed with breast cancer during the 8.3 years of dietary intervention. While differences were not statistically significant, there were fewer breast cancers diagnosed in the low fat dietary group women (HR 0.92 95% CI 0.84-1.01, P=0.09) with somewhat lower breast cancer mortality (HR 0.77 95% CI 0.48-1.22) than seen in control group women (JAMA 2006; 295:629). These findings were recently updated, and after 10.9 years (mean) post-diagnosis follow-up, breast...
Source: Cancer Research - February 13, 2017 Category: Cancer & Oncology Authors: RT Chlebowski, AK Aragaki, CA Thomson, G Anderson, JE Manson, MS Simon, TE Rohan, LG Snetselar, D Lane, WE Barrington, M Vitolins, C Womack, L Qi, L Hou, F Thomas, RL Prentice Tags: General Session Abstracts Source Type: research

Impact of a targeted direct marketing price promotion intervention (Buywell) on food ‐purchasing behaviour by low income consumers: a randomised controlled trial
ConclusionsShort‐term direct marketing price promotions combined with healthy eating advice and recipe suggestions targeted at low income consumers are feasible and can have a modest impact on short‐term food‐purchasing behaviour, although further approaches are needed to help sustain these changes. (Source: Journal of Human Nutrition and Dietetics)
Source: Journal of Human Nutrition and Dietetics - January 31, 2017 Category: Nutrition Authors: M. Stead, A. M. MacKintosh, A. Findlay, L. Sparks, A. S. Anderson, K. Barton, D. Eadie Tags: Research Paper Source Type: research

Effects on Metabolites of Dietary Sodium: The Dietary Approaches to Stop Hypertension (DASH)-Sodium Feeding Study
We report relations between metabolic pathways and low sodium intake by combining individual metabolite P values with the use of Fisher’s exact test. Of the 36 metabolic pathways tested, 6 were associated with sodium intake, with a P value <0.005 (i.e., benzoate, tryptophan, plant components, -glutamyl amino acid, fatty acid, and methionine metabolism). Of the 681 named metabolites tested, 82 were associated with sodium intake at a false discovery rate <0.2. The metabolites with the strongest associations, independent of blood pressure, were 4-ethylphenysulfate and 4-hydroxyphenylpyruvate, which increased, and ...
Source: Advances in Nutrition - January 19, 2017 Category: Nutrition Authors: Stozlenberg-Solomon, R., Derkach, A., Josephs, J., Playdon, M., Sampson, J. Tags: Variability in Responses to Diet and Food Source Type: research

Influence of Lipid Content in a Corn Oil Preparation on the Bioaccessibility of β‐Carotene: A Comparison of Low‐Fat and High‐Fat Samples
Abstract Some individuals with fat maldigestion have compromised digestive systems, which causes the incomplete hydrolyzation of ingested lipids within the gastrointestinal tract (GIT). We studied the influence of high‐fat (20%) and low‐fat (4%) contents on the bioaccessibility of a highly hydrophobic nutraceutical (β‐carotene) through a simulated GIT model consisting of mouth, stomach, and small intestine phases. The low‐fat and high‐fat values were chosen to simulate low‐fat and high‐fat diets. The triglycerides in the low‐fat system were fully digested, whereas those in the high‐fat system were only p...
Source: Journal of Food Science - January 18, 2017 Category: Food Science Authors: Ziyuan Xia, David Julian McClements, Hang Xiao Tags: Food Chemistry Source Type: research

Reversal of high fat diet-induced obesity improves glucose tolerance, inflammatory response, β-amyloid accumulation and cognitive decline in the APP/PSEN1 mouse model of Alzheimer's disease.
This study assessed the extent to which high fat diet (HFD)-induced β-amyloid accumulation and cognitive decline in APP/PSEN1 mice are reversible through control of fat intake. Ten months of HFD (60% calories from fat) led to significant deficits in a 2-trial Y maze task, and nest building assay, and decreased voluntary locomotor activity. The HFD induced an inflammatory response, indicated by increased expression of several inflammatory markers. Substituting a low fat diet led to pronounced weight loss and correction of glucose intolerance, decreases in the inflammatory response, and improved performance on behavioral ta...
Source: Neurobiology of Disease - January 16, 2017 Category: Neurology Authors: Walker JM, Dixit S, Saulsberry AC, May JM, Harrison FE Tags: Neurobiol Dis Source Type: research

Octenyl succinylation of granular and debranched waxy starches and their application in low-fat salad dressing
Publication date: May 2017 Source:Food Hydrocolloids, Volume 66 Author(s): Nuengmaysa Klaochanpong, Santhanee Puncha-arnon, Dudsadee Uttapap, Chureerat Puttanlek, Vilai Rungsardthong The reactions of octenyl succinic anhydride (OSA) at 3% and 15% concentrations (based on weight of starch) with granular and debranched starch forms of waxy rice and waxy potato starches were investigated and compared. Reaction efficiencies of debranched starches with 3% OSA (83.6–87.4%) were significantly higher than those of the granular starches (51.2–56.1%), but their recovery yields were lower (80–85% and 94–98% for debranc...
Source: Food Hydrocolloids - January 11, 2017 Category: Food Science Source Type: research

Metabolomic profiles as reliable biomarkers of dietary composition.
CONCLUSIONS: Metabolomic profiling may be used to assess compliance during clinical nutrition trials and the validity of dietary assessment in observational studies. In addition, this methodology may help elucidate mechanistic pathways linking diet to chronic disease risk. This trial was registered at clinicaltrials.gov as NCT00315354. PMID: 28077380 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - January 10, 2017 Category: Nutrition Authors: Esko T, Hirschhorn JN, Feldman HA, Hsu YH, Deik AA, Clish CB, Ebbeling CB, Ludwig DS Tags: Am J Clin Nutr Source Type: research

Optimizing the effects of Persian gum and carrot pomace powder for development of low-fat donut with high fibre content
The objective of present study was to develop and optimize a low-fat high fibre donut formulation using response surface methodology. A 5-level-3-factor central composite rotatable design was employed, where the independent variables were Persian gum (0–1.5g/100g), carrot pomace powder (0–15g/100g) and water (38–53g/100g), while the dependent variables were physicochemical properties of donuts. It was found that Persian gum and carrot pomace powder both effectively contributed to retention of donuts moisture content which in turn led to significant reduction of fat uptake during frying process (p &lt; 0.05). Pers...
Source: Bioactive Carbohydrates and Dietary Fibre - January 9, 2017 Category: Food Science Source Type: research

Consumption of low-fat dairy, but not whole-fat dairy, is inversely associated with depressive symptoms in Japanese adults
ConclusionsThe current results indicate that a higher frequency of low-fat dairy consumption may be associated with a lower prevalence of depressive symptoms. (Source: Social Psychiatry and Psychiatric Epidemiology)
Source: Social Psychiatry and Psychiatric Epidemiology - January 8, 2017 Category: Psychiatry Source Type: research

High-Carbohydrate/Low-Fat Diet-Induced Gender-Specific Serum Lipid Profile Changes Are Associated with < b > < i > LEPR < /i > < /b > Polymorphisms in Chinese Youth
Conclusions:LEPR polymorphisms contribute to the heterogeneities in BMI, LDL-C, and HDL-C responsiveness that are induced by a HC/LF diet in healthy young Chinese adults.Ann Nutr Metab 2017;70:1-8 (Source: Annals of Nutrition and Metabolism)
Source: Annals of Nutrition and Metabolism - January 6, 2017 Category: Nutrition Source Type: research

The rs1862513 Variant in Resistin Gene-Modified Insulin Resistance and Insulin Levels after Weight Loss Secondary to Hypocaloric Diet
Conclusion: The present study suggests that the G/G genotype ofRETN rs1862513 could be a predictor of the reduction of HOMA-IR, insulin, fasting glucose and LDL cholesterol secondary to a hypocaloric diet in obese subjects.Ann Nutr Metab 2016;69:256-262 (Source: Annals of Nutrition and Metabolism)
Source: Annals of Nutrition and Metabolism - January 6, 2017 Category: Nutrition Source Type: research

Improving the shelf life of low-fat cut cheese using nanoemulsion-based edible coatings containing oregano essential oil and mandarin fiber
Publication date: June 2017 Source:Food Control, Volume 76 Author(s): María Artiga-Artigas, Alejandra Acevedo-Fani, Olga Martín-Belloso Nanoemulsion-based edible coatings containing oregano essential oil (OEO) as antimicrobial were applied onto low-fat cut cheese to extend its shelf life. Nanoemulsions formulation was 2.0% (w/w) sodium alginate, 0.5% (w/w) mandarin fiber, 2.5% (w/w) Tween 80 and 1.5%, 2.0% or 2.5% (w/w) of OEO. Particle size, ζ-potential, apparent viscosity and whiteness index of nanoemulsions were assessed. Water vapor resistance of coatings was evaluated as well as their antimicrobial efficiency ...
Source: Food Control - January 5, 2017 Category: Food Science Source Type: research

Physico-chemical properties of functional low-fat beef burgers: Fatty acid profile modification
This study was undertaken to produce low-fat beef burgers (6%); with the incorporation of prebiotic fibers (a mixture of 3.1% inulin and 2.2% β-glucan) and canola and olive oils as beef fat substitutes. Composition (proximate analysis and fatty acid profile), technological properties (Cooking and texture properties) and sensory properties were evaluated in comparison to control burgers (12.5% beef fat) which are regarded as a traditional burger in the local market. The applied lipid modification improved the fatty acid profile and nutrimental value of burgers by decreasing the percentage of SFAs content (from 48% to ∼19...
Source: LWT Food Science and Technology - January 3, 2017 Category: Food Science Source Type: research

Visceral adiposity and metabolic syndrome after very high-fat and low-fat isocaloric diets: a randomized controlled trial [Nutritional status, dietary intake, and body composition]
Conclusions: Consuming energy primarily as carbohydrate or fat for 3 mo did not differentially influence visceral fat and metabolic syndrome in a low-processed, lower-glycemic dietary context. Our data do not support the idea that dietary fat per se promotes ectopic adiposity and cardiometabolic syndrome in humans. This study was registered at clinicaltrials.gov as NCT01750021. (Source: American Journal of Clinical Nutrition)
Source: American Journal of Clinical Nutrition - January 2, 2017 Category: Nutrition Authors: Veum, V. L., Laupsa-Borge, J., Eng, O., Rostrup, E., Larsen, T. H., Nordrehaug, J. E., Nygard, O. K., Sagen, J. V., Gudbrandsen, O. A., Dankel, S. N., Mellgren, G. Tags: Obesity and Metabolism Research Articles Nutritional status, dietary intake, and body composition Source Type: research

Green tea epigallocatechin 3-gallate alleviates hyperglycemia and reduces advanced glycation end products via nrf2 pathway in mice with high fat diet-induced obesity.
This study demonstrated that EGCG has the potential to help control hyperglycemia, reduce weight, and alleviate diabetes complications. PMID: 28040599 [PubMed - as supplied by publisher] (Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie)
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - December 28, 2016 Category: Drugs & Pharmacology Authors: Sampath C, Rashid MR, Sang S, Ahmedna M Tags: Biomed Pharmacother Source Type: research