Scoping review of non-surgical treatment options for macular holes
This study conducted a comprehensive literature review and analysis of non-surgical MH management.A systematic literature search was conducted on PubMed, Embase, Scopus, and the Cochrane Library from January 1, 1973, to September 13, 2023. Treatments included laser therapy, carbonic anhydrase inhibitors (CAIs), non-steroidal anti-inflammatories (NSAIDs), steroids (topical, subtenons, peribulbar, intravitreal), intravitreal gas, anti-vascular endothelial growth factors (VEGF) and ocriplasmin injections. (Source: Survey of Ophthalmology)
Source: Survey of Ophthalmology - April 25, 2024 Category: Opthalmology Authors: Yong Min Lee, Bobak Bahrami, Dinesh Selva, Robert J Casson, Weng Onn Chan Tags: Review article Source Type: research

755-nm picosecond laser plus topical 20% azelaic acid compared to topical 20% azelaic acid alone for the treatment of melasma: a randomized, split-face and controlled trial
Conclusion: The additional use of picosecond laser therapy showed no clinical difference except for subtle differences detected by RCM assessments.The study was registered in the Chinese Clinical Trial Registry (ChiCTR2100051294; 18 September 2021). (Source: Lasers in Medical Science)
Source: Lasers in Medical Science - April 24, 2024 Category: Laser Surgery Source Type: research

Bio-thermal response during laser haemorrhoidoplasty: an exclusive analytical and numerical approach for theoretical investigation
Lasers Med Sci. 2024 Apr 22;39(1):108. doi: 10.1007/s10103-024-04046-7.ABSTRACTHaemorrhoidal disease is identified by declension of the inflamed and bleeding of vascular tissues of the anal canal. Traditionally, haemorrhoids are associated with chronic constipation and the most common symptoms are irritation in anus region, pain and discomfort, swelling around anus, tender lumps around the anus and rectal bleeding (depending upon the grade of haemorrhoid). Among the several conventional treatment procedures (commonly mentioned as, rubber band litigation, sclerotherapy and electrotherapy), laser haemorrhoidoplasty is an out...
Source: Anal Sci - April 22, 2024 Category: Chemistry Authors: Jaideep Dutta Source Type: research

Bio-thermal response during laser haemorrhoidoplasty: an exclusive analytical and numerical approach for theoretical investigation
AbstractHaemorrhoidal disease is identified by declension of the inflamed and bleeding of vascular tissues of the anal canal. Traditionally, haemorrhoids are associated with chronic  constipation and the most common symptoms are irritation in anus region, pain and discomfort, swelling around anus, tender lumps around the anus and rectal bleeding (depending upon the grade of haemorrhoid). Among the several conventional treatment procedures (commonly mentioned as, rubber band li tigation, sclerotherapy and electrotherapy), laser haemorrhoidoplasty is an out-patient and less-invasive laparoscopic procedure. From literature s...
Source: Lasers in Medical Science - April 22, 2024 Category: Laser Surgery Source Type: research

Clinical and ex-vivo effect of LASERs on prevention of early-enamel caries: systematic review & amp; meta-analyses
AbstractTo investigate the in vivo and in situ effect of different types of lasers in prevention of enamel demineralization in high caries risk cases (around orthodontic brackets, around restoration and in caries susceptible pits and fissures). PubMed was searched using the following keyword sequence; (Laser therapy OR laser irradiation OR laser application) AND (enamel caries prevention OR enamel demineralization OR enamel remineralization OR early enamel caries OR early-enamel caries OR enamel resistance OR enamel decalcification OR white spot lesions WSLs OR incipient lesion OR enamel decay OR enamel Dissolution OR enam...
Source: Lasers in Medical Science - April 18, 2024 Category: Laser Surgery Source Type: research

Cancers, Vol. 16, Pages 1548: Oral Mucositis Management in Children under Cancer Treatment: A Systematic Review
ilva Children undergoing antineoplastic treatment often present severe side effects due to the dosage and duration of treatments, with oral mucositis emerging as one of the most prevalent and painful inflammatory conditions. There is a growing body of evidence on therapeutic interventions such as cryotherapy, low-level laser therapy, and natural compounds for this condition. The aim of this systematic review was to identify and compare therapies for the management of cancer treatment-induced oral mucositis in pediatric patients. From 2655 articles obtained in initial searches, 39 articles were considered in this system...
Source: Cancers - April 18, 2024 Category: Cancer & Oncology Authors: Ricardo Bragu ês Maria Francisca Marv ão Patr ícia Correia Raquel M. Silva Tags: Systematic Review Source Type: research

The effect of low-level laser therapy on the oxidative stress level and quality of life in patients with Hashimoto's thyroiditis
This study aimed to examine the effects of low-level laser therapy (LLLT) combined with levothyroxine replacement therapy on thyroid function, oxidative stress (OS), and quality of life in patients with Hashimoto's thyroiditis (HT). Forty-six patients diagnosed with HT were randomized to receive active LLLT (n = 23) and sham LLLT (n = 23) twice a week for three weeks. Clinical and laboratory evaluations of the participants were performed before treatment and three months after treatment. Biochemical parameters were taken from the patient file requested by the physician as a routine examination. Malondialdehyde and nitricox...
Source: Free Radical Research - April 17, 2024 Category: Research Authors: S ümeyye Tunç Şükriye Leyla Altuntaş Murat Atmaca Çağrı Çakıcı T ürkan Yiğitbaşı Yeong-Cheng Liou Wei-An Chang Source Type: research

The effect of high-intensity laser therapy on pain and lower extremity function in patellofemoral pain syndrome: a single-blind randomized controlled trial
This study indicated that high-intensity laser therapy was found to be a more effective method in the treatment of patellofemoral pain syndrome after 3 months of follow-up compared to US-TENS combination and US-interferential current combination treatments. Also, HILT can be used as an effective method in combination with an appropriate exercise program including vastus medialis strengthening to reduce pain and increase functionality in the patients with PFPS. (Source: Lasers in Medical Science)
Source: Lasers in Medical Science - April 17, 2024 Category: Laser Surgery Source Type: research

Weekly Laser Treatments for Port-Wine Birthmarks in Infants
This case series examines the improvement in port-wine birthmark clearance from before to after once-weekly pulsed dye laser therapy in patients younger than 6 months. (Source: JAMA Dermatology)
Source: JAMA Dermatology - April 17, 2024 Category: Dermatology Source Type: research

Laser therapy decreases oral leukoplakia recurrence and boosts patient comfort: a network meta-analysis and systematic review
Oral leukoplakia (OLK) is a prevalent precancerous lesion with limited non-pharmacological treatment options. Surgery and various lasers are the mainstay of treatment; however, their relative efficacy and opti... (Source: BMC Oral Health)
Source: BMC Oral Health - April 17, 2024 Category: Dentistry Authors: Rui Luo, Yanan Wang, Ruixin Li, Yanan Ma, Haitao Chen, Jian Zhang and Jun Shen Tags: Systematic Review Source Type: research

Advancements in De Quervain Tenosynovitis Management: A Comprehensive Network Meta-Analysis
CONCLUSIONS: Corticosteroid injection with a short duration of immobilization remains the primary and effective treatment for De Quervain tenosynovitis. Extracorporeal shockwave therapy can be considered a secondary option. Alternative treatment modalities, such as isolated therapeutic injection, should be approached with caution because they did not show substantial benefits over placebo.TYPE OF STUDY/LEVEL OF EVIDENCE: Therapeutic I.PMID:38613563 | DOI:10.1016/j.jhsa.2024.03.003 (Source: Hand Surgery)
Source: Hand Surgery - April 13, 2024 Category: Surgery Authors: Han Hong Chong Akhilesh Pradhan Mohit Dhingra William Liong Melinda Y T Hau Rohi Shah Source Type: research

Advancements in De Quervain Tenosynovitis Management: A Comprehensive Network Meta-Analysis
CONCLUSIONS: Corticosteroid injection with a short duration of immobilization remains the primary and effective treatment for De Quervain tenosynovitis. Extracorporeal shockwave therapy can be considered a secondary option. Alternative treatment modalities, such as isolated therapeutic injection, should be approached with caution because they did not show substantial benefits over placebo.TYPE OF STUDY/LEVEL OF EVIDENCE: Therapeutic I.PMID:38613563 | DOI:10.1016/j.jhsa.2024.03.003 (Source: Hand Surgery)
Source: Hand Surgery - April 13, 2024 Category: Surgery Authors: Han Hong Chong Akhilesh Pradhan Mohit Dhingra William Liong Melinda Y T Hau Rohi Shah Source Type: research

Novel Drug Delivery Approaches for the Localized Treatment of Cervical Cancer
AAPS PharmSciTech. 2024 Apr 11;25(4):85. doi: 10.1208/s12249-024-02801-1.ABSTRACTCervical cancer (CC) is the fourth leading cancer type in females globally. Being an ailment of the birth canal, primitive treatment strategies, including surgery, radiation, or laser therapy, bring along the risk of infertility, neonate mortality, premature parturition, etc. Systemic chemotherapy led to systemic toxicity. Therefore, delivering a smaller cargo of therapeutics to the local site is more beneficial in terms of efficacy as well as safety. Due to the regeneration of cervicovaginal mucus, conventional dosage forms come with the limi...
Source: AAPS PharmSciTech - April 11, 2024 Category: Drugs & Pharmacology Authors: Ivy Saha Jitu Halder Tushar Kanti Rajwar Ritu Mahanty Deepak Pradhan Priyanka Dash Chandan Das Vineet Kumar Rai Biswakanth Kar Goutam Ghosh Goutam Rath Source Type: research