TWiV 602: Coronavirus immunology with Stanley Perlman
Stanley Perlman joins TWiV to discuss immune responses to coronaviruses, including seasonal CoV, MERS, SARS, and SARS-CoV-2, including prospects for a vaccine. Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker Guest: Stanley Perlman Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Perlman Laboratory An Iowa Caucus of Viruses (TWiV 538) Anti-SARS-CoV spike IgG and acute lung injury (JCI Insight) T cell responses to respiratory CoV (Immunol Res) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees. Send your virology questions an...
Source: This Week in Virology - MP3 Edition - April 16, 2020 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 588: Coronavirus update - Save the pangolin!
The TWiV team returns this week to SARS-CoV-2019 coverage to review the latest epi curves, the fatality rate, furin cleavage site and receptor binding domain in the spike glycoprotein, related CoV recovered from pangolins, evidence that the virus did not escape from a laboratory, and many more questions sent in by listeners. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Kathy Spindler Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode WHO CoV sitreps Epidemiology of COVID-19 (China CDC) COVID-19 incubation period (J Med Virol) China clinical tria...
Source: This Week in Virology - MP3 Edition - February 23, 2020 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 583: Galveston virus hunters
Vincent and Rich travel to Galveston National Laboratory to speak with Jim LeDuc, Tom Ksiazek, and Bob Tesch about their long careers as virus hunters. Hosts: Vincent Racaniello and Rich Condit Guests: Jim LeDuc, Tom Ksiazek, and Bob Tesh Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv (Source: This Week in Virology - MP3 Edition)
Source: This Week in Virology - MP3 Edition - January 19, 2020 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
Testing for TB is only skin deep
A TB infection can take two forms, active and latent. Active disease is transmissible, and causes the damage to the lungs which makes TB one of the biggest killers in the world.
In the latent form, the bacteria Mycobacterium tuberculosis is quiescent and can stay that way for years until it becomes active and causes those clinical signs.
Testing for the active version of the disease is done directly, but when it comes to latency, we use the tuberculin skin test to see if someone has an immunological response - and when that happens we consider them to have latent disease.
However, in this podcast Lalita Ramakrishnan, p...
Source: The BMJ Podcast - October 25, 2019 Category: General Medicine Authors: BMJ talk medicine Source Type: podcasts
Testing for TB is only skin deep
A TB infection can take two forms, active and latent. Active disease is transmissible, and causes the damage to the lungs which makes TB one of the biggest killers in the world.
In the latent form, the bacteria Mycobacterium tuberculosis is quiescent and can stay that way for years until it becomes active and causes those clinical signs.
Testing for the active version of the disease is done directly, but when it comes to latency, we use the tuberculin skin test to see if someone has an immunological response - and when that happens we consider them to have latent disease.
However, in this podcast Lalita Ramakrishnan, pr...
Source: The BMJ Podcast - October 25, 2019 Category: General Medicine Authors: BMJ Group Source Type: podcasts
TWiV 555: Fidelity and the single cell
From ASM Microbe 2019, Vincent, Brianne and Calvin meet up with Craig Cameron to discuss his career and his work exploring RNA-dependent RNA synthesis and single cell virology. Hosts: Vincent Racaniello, Brianne Barker, and Calvin Yeager Guest: Craig Cameron Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Cameron laboratory Curioscity podcast Ribavirin is an RNA virus mutagen (Nat Med) RNA virus error catastrophe: test using ribavirin (PNAS) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe...
Source: This Week in Virology - MP3 Edition - July 7, 2019 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
Creating chimeras for organ transplants and how bats switch between their eyes and ears on the wing
Researchers have been making animal embryos from two different species, so-called “chimeras,” for years, by introducing stem cells from one species into a very early embryo of another species. The ultimate goal is to coax the foreign cells into forming an organ for transplantation. But questions abound: Can evolutionarily distant animals, like pigs and humans, be mixed togeth er to produce such organs? Or could species closely related to us, like chimps and macaques, stand in for tests with human cells? Staff Writer Kelly Servick joins host Sarah Crespi to discuss the research, the regulations, and the growing ethical ...
Source: Science Magazine Podcast - June 27, 2019 Category: Science Authors: Science Tags: Scientific Community Source Type: podcasts
Creating chimeras for organ transplants and how bats switch between their eyes and ears on the wing
Researchers have been making animal embryos from two different species, so-called “chimeras,” for years, by introducing stem cells from one species into a very early embryo of another species. The ultimate goal is to coax the foreign cells into forming an organ for transplantation. But questions abound: Can evolutionarily distant animals, like pigs and humans, be mixed together to produce such organs? Or could species closely related to us, like chimps and macaques, stand in for tests with human cells? Staff Writer Kelly Servick joins host Sarah Crespi to discuss the research, the regulations, and the growing ethical d...
Source: Science Magazine Podcast - June 27, 2019 Category: Science Authors: Science Magazine Source Type: podcasts
Creating chimeras for organ transplants and how bats switch between their eyes and ears on the wing
Researchers have been making animal embryos from two different species, so-called “chimeras,” for years, by introducing stem cells from one species into a very early embryo of another species. The ultimate goal is to coax the foreign cells into forming an organ for transplantation. But questions abound: Can evolutionarily distant animals, like pigs and humans, be mixed togeth er to produce such organs? Or could species closely related to us, like chimps and macaques, stand in for tests with human cells? Staff Writer Kelly Servick joins host Sarah Crespi to discuss the research, the regulations, and the growing ethical ...
Source: Science Magazine Podcast - June 27, 2019 Category: Science Authors: Science Tags: Scientific Community Source Type: podcasts
Creating chimeras for organ transplants and how bats switch between their eyes and ears on the wing
Researchers have been making animal embryos from two different species, so-called “chimeras,” for years, by introducing stem cells from one species into a very early embryo of another species. The ultimate goal is to coax the foreign cells into forming an organ for transplantation. But questions abound: Can evolutionarily distant animals, like pigs and humans, be mixed togeth er to produce such organs? Or could species closely related to us, like chimps and macaques, stand in for tests with human cells? Staff Writer Kelly Servick joins host Sarah Crespi to discuss the research, the regulations, and the growing ethical ...
Source: Science Magazine Podcast - June 27, 2019 Category: Science Authors: Science Tags: Scientific Community Source Type: podcasts
"Next Wave" -- The Discovery Files
An NSF-funded wave research laboratory sets the stage to study the structural integrity of buildings under severe weather conditions, which could help engineers devise better building codes and standards to protect future coastal structures. (Source: The Discovery Files)
Source: The Discovery Files - June 13, 2019 Category: Science Authors: National Science Foundation Source Type: podcasts
TWiV 531: Circ du RNA
Patrick Moore returns to TWiV to discuss the discovery from the Chang-Moore laboratory of circular RNAs in cells infected with herpesviruses. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Kathy Spindler Guest: Patrick Moore Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Please take the TWiV listener survey ASV 2019 European Congress of Virology 2019 ASM Clinical Virology Symposium Intel ISEF judges needed Cancer virology at Pitt Alice Huang’s DI particles (PubMed) Circular DNA tumor viruses make circular RNAs (PNAS) Backsplice Image credit ...
Source: This Week in Virology - MP3 Edition - January 20, 2019 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 530: Quiet please!
Steve Goff returns to TWiV to discuss the work of his laboratory on how retroviral genomes are silenced in infected cells. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Kathy Spindler Guest: Steve Goff Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! 🎼 They’ll histone you when you start to transcribe, And they’ll histone you just for tryin’ to get by, So be careful when you uncoat your genome, ‘Cause everybody must histone. Links for this episode Please take the TWiV listener survey ASV 2019 European Congress of Virology 2019 Histones loaded onto incoming r...
Source: This Week in Virology - MP3 Edition - January 13, 2019 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
