TWiV 696: Tear down that SARS-CoV-2 manuscript
TWiV explains that COVID-19 is not harmless for young adults, FAA approval for Pfizer mRNA vaccine, lack of justification for the claim of reverse transcription of SARS-CoV-2 RNA and integration into the human genome, and lack of evidence for increased transmission by new variants in the UK. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Brianne Barker Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode BSL-3 laboratory assistant manager position FDA authorizes EUA for Moderna mRNA vaccine (FDA) COVID-19 is not harmless for young adults (...
Source: This Week in Virology - MP3 Edition - December 20, 2020 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 693: Vax to the future
On this episode, FDA EUA for Pfizer mRNA vaccine, efficacy of AstraZeneca ChAdOx1 COVID-19 vaccine, and an orally administered drug that blocks SARS-CoV-2 transmission in ferrets. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Brianne Barker Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode BSL-3 laboratory assistant manager position FDA advisory committee votes in favor of EUA for Pfizer vaccine (NY Times) Sanofi/Glaxo subunit vaccine steps back (Stat) Efficacy of ChAdOx1 COVID-19 vaccine (Lancet) Oral antiviral blocks SARS-CoV-2 trans...
Source: This Week in Virology - MP3 Edition - December 13, 2020 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 668: Mice, bats, and coronaviruses with Tony Schountz
Tony Schountz joins TWiV to explain the work of his laboratory showing that deer mice can be infected with and transmit SARS-CoV-2, and how his colony of Jamaican fruit bats is being used to understand their response to virus infections. Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler and Brianne Barker Guest: Tony Schountz Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode SARS-CoV-2 infection of deer mice (bioRxiv) Infection of Jamaican fruit bats with MERS-CoV (Sci Rep) Immunological control of virus infections in bats (Front Immunol) Transmission of bat ...
Source: This Week in Virology - MP3 Edition - October 1, 2020 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 664: TWiV is for the dogs
On this mid-week edition, does it matter that SARS-CoV-2 is mutating, seasonal coronavirus immunity is short-lived, another bogus claim that the virus was produced in a laboratory (it came from Nature), and answers to listener questions. Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler and Brianne Barker Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Coronavirus is mutating (Nature) Seasonal CoV immunity is short (Nat Med) Sorry, no link to the fake science document! Letters read on TWiV 664 Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees ...
Source: This Week in Virology - MP3 Edition - September 17, 2020 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 656: See, it can be done!
Daniel Griffin provides a clinical report on COVID-19, surgeons Lisa Smith and David Bruce detail how they have helped their Chattanooga community during the pandemic, then we discuss racial and ethnic disparities among COVID-19 cases, no more premarket review of laboratory developed tests by FDA; and emergency use authorization of convalescent plasma is on hold. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Brianne Barker Guests: Daniel Griffin, Lisa A. Smith, and W. David Bruce Subscribe (free): iTunes, Google Podcasts, RSS, email Links for this episode Racial and ethnic disparities in workplace...
Source: This Week in Virology - MP3 Edition - August 23, 2020 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 651: FDA rules with Denise Esposito
Daniel Griffin provides a clinical report on COVID-19, then former FDA Chief of Staff to the Commissioner Denise Esposito joins us to explain the challenges in approving vaccines, antiviral drugs, and diagnostic tests during a pandemic, followed by answers to listener questions. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Brianne Barker Guests: Daniel Griffin and Denise Esposito Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Template for at-home, OTC diagnostic tests (FDA) Postdoctoral position in Prasad laboratory (pdf) Rapidte...
Source: This Week in Virology - MP3 Edition - August 9, 2020 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 645: Lions and tigers and zookeepers (oh my)
Daniel Griffin provides a clinical report on COVID-19, followed by a review of the State Department document on the Wuhan BSL-4 laboratory, the report on infection of tigers and lions in the Bronx Zoo, and, answers to listener questions. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Brianne Barker Guest: Daniel Griffin Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode State Dept. memo on Wuhan BSL-4 lab (pdf) Biosafety levels (Wikipedia) Inside a BSL-4 (TWiV) From people to panthers (bioRxiv) Letters read on TWiV 645 Timestamps by Jol...
Source: This Week in Virology - MP3 Edition - July 26, 2020 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
Attention Networks: The role of NE
Attention has been studied heavily and as per a popular model of attention by Posner et al, we have 3 systems for attention: alerting, orienting and an executive control network.
Now let me propose a radical fourth network for the same, but before I do that I want to clear some misconceptions about attention. Way back in 2009 I had blogged and elaborated on a couple of posts that attention allocation and action selection utilized the same mechanisms and were conceptually similar; at that time I was not much aware of the Posner et al model of attention. Today I want to go further and claim that attention processes are in...
Source: The Mouse Trap - June 30, 2020 Category: Psychiatry & Psychology Authors: sandygautam Tags: attention neurotransmitters Source Type: podcasts
TWiV 628: Physical distance for COVID-19
Vincent and Rich discuss the SARS-CoV-2 D614G amino acid change in the spike glyprotein, duration of infectious virus shedding from patients, virus transmission among hamsters infected in the laboratory, and tackle listener email. Hosts: Vincent Racaniello and Rich Condit Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Austin TX key indicators for staging D614 amino acid change (Scripps) Virus shedding in hospitalized patients (medRxiv) Hamster SARS-CoV-2 model (Nature) COVID-19 host genetic initiative Image credit Letters read on TWiV 628 Timestamps by Jolene. ...
Source: This Week in Virology - MP3 Edition - June 18, 2020 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 627: Singapore National Centre for Infectious Diseases
Vincent visits the National Centre for Infectious Diseases and speaks with Executive Director Leo Yee-Sin and Consultant Nancy Tee about the main hub for both clinical treatment of infectious diseases and outbreak management in Singapore. Host: Vincent Racaniello Guests: Leo Yee-Sin and Nancy Tee Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode National Centre for Infectious Diseases National Public Health Laboratory Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv (Source: This Week in Virology - MP3 Edition)
Source: This Week in Virology - MP3 Edition - June 17, 2020 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 626: Ralph Baric and fancy ferrets
Daniel Griffin provides a clinical update on COVID-19, then Ralph Baric joins TWiV to discuss SARS-CoV-2 transmission, vaccines, diagnostic tests, and a new animal model from his laboratory that does not use transgenic mice. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Brianne Barker Guests: Daniel Griffin, Chuck Knirsch, and Ralph Baric Subscribe (free): iTunes, Google Podcasts, RSS, email Links for this episode Mouse-adapted SARS-CoV-2 model (bioRxiv) SARS-CoV-2 mRNA vaccine (bioRxiv) ASM resources for #shutdownstem President Obama on sustaining momentum for change (Facebook) America Af...
Source: This Week in Virology - MP3 Edition - June 14, 2020 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 619: Recombination led to emergence of SARS-CoV-2
Raul Rabadan joins TWiV to explain the use of computational biology to demonstrate how recombination and mutation led to emergence of SARS-CoV-2. Hosts: Vincent Racaniello, Rich Condit, and Brianne Barker Guest: Raul Rabadan Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Rabadan Laboratory Understanding Coronavirus (Amazon) Topological Data Analysis for Genomics and Evolution (Amazon) Recombination and mutation shaped SARS-CoV-2 (bioRxiv) Bat CoV with cleavage site insertion (Curr Biol) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees. Send your ...
Source: This Week in Virology - MP3 Edition - May 27, 2020 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
ASFH Implanting an Artificial Retina – part 2
Guest: Daniel Palanker, PhD Professor, Department of Ophthalmology Director, Hansen Experimental Physics Laboratory Stanford University Stanford, CA (Source: As Seen From Here)
Source: As Seen From Here - May 15, 2020 Category: Opthalmology Authors: JYoungMD at gmail.com Source Type: podcasts
ASFH Implanting an Artificial Retina – part 1
Guest: Daniel Palanker, PhD Professor, Department of Ophthalmology Director, Hansen Experimental Physics Laboratory Stanford University Stanford, CA (Source: As Seen From Here)
Source: As Seen From Here - May 1, 2020 Category: Opthalmology Authors: JYoungMD at gmail.com Source Type: podcasts
