Contents
Brett A. Sponseller (Source: Veterinary Clinics of North America: Equine Practice)
Source: Veterinary Clinics of North America: Equine Practice - March 9, 2023 Category: Veterinary Research Source Type: research

Forthcoming Issues
Equine Colic (Source: Veterinary Clinics of North America: Equine Practice)
Source: Veterinary Clinics of North America: Equine Practice - March 9, 2023 Category: Veterinary Research Source Type: research

Infectious Causes of Equine Placentitis and Abortion
A variety of infectious agents including viral, bacterial, and fungal organisms can cause equine abortion and placentitis. Knowledge of normal anatomy and the common pattern distribution of different infectious agents will assist the practitioner in evaluating the fetus and/or placenta, collecting appropriate samples for further testing, and in some cases, forming a presumptive diagnosis. In all cases, it is recommended to confirm the diagnosis with molecular, serologic, or microbiological testing. If a causative agent can be identified, then appropriate biosecurity and vaccination measures can be instituted on the farm. (...
Source: Veterinary Clinics of North America: Equine Practice - February 1, 2023 Category: Veterinary Research Authors: Rebecca E. Ruby, Jennifer G. Janes Source Type: research

Equine Rotaviral Diarrhea
Equine rotavirus is one of the most common causes of infectious diarrhea in foals. Although the infection itself is self-limiting, the resulting diarrhea is due to multiple mechanisms and can be severe, requiring supportive care including fluid and electrolyte support. Prompt diagnosis is important for treatment and biosecurity decisions and can be achieved by several means. Prevention, while imperfect, currently relies on vaccination of pregnant mares before parturition, ingestion of adequate colostrum from vaccinated mares and biosecurity measures. (Source: Veterinary Clinics of North America: Equine Practice)
Source: Veterinary Clinics of North America: Equine Practice - February 1, 2023 Category: Veterinary Research Authors: Jamie J. Kopper Source Type: research

Vesicular Stomatitis Virus
Vesicular stomatitis (VS) is a vector-borne livestock disease caused by vesicular stomatitis New Jersey virus (VSNJV) or vesicular stomatitis Indiana virus (VSIV). The disease circulates endemically in northern South America, Central America, and Mexico and only occasionally causes outbreaks in the United States. Over the past 20  years, VS outbreaks in the southwestern and Rocky Mountain regions occurred periodically with incursion years followed by virus overwintering and subsequent expansion outbreak years. The regulatory response by animal health officials prevents the spread of disease by animals with lesions and man...
Source: Veterinary Clinics of North America: Equine Practice - February 1, 2023 Category: Veterinary Research Authors: Angela M. Pelzel-McCluskey Source Type: research

Salmonella in Horses
Managing Salmonella in equine populations can be challenging due to the epidemiology of this disease. In particular, due to the range of clinical outcomes, the occurrence of subclinical infections, and intermittent shedding. This greatly affects the ability to detect shedding and can lead to widespread environmental contamination and transmission. The veterinary profession can reduce the risk to stablemates and their caretakers, while meeting their ethical obligation, by appropriately managing these risks within animal populations and environments. (Source: Veterinary Clinics of North America: Equine Practice)
Source: Veterinary Clinics of North America: Equine Practice - February 1, 2023 Category: Veterinary Research Authors: Brandy A. Burgess Source Type: research

Streptococcus equi Subspecies equi
Strangles, caused by the bacteria Streptococcus equi subsp equi, is a highly contagious disease of equids classically characterized by a high fever and enlarged lymph nodes of the head. Diagnostic sampling depends on the stage of the disease. The goal of treating strangles is to control transmission and to eliminate infection while providing future host immunity. Daily temperature checking and isolation of febrile horses is the key to controlling outbreaks. Eradication of this disease will not be possible until S equi carriers are eliminated from the equine population. (Source: Veterinary Clinics of North America: Equine Practice)
Source: Veterinary Clinics of North America: Equine Practice - February 1, 2023 Category: Veterinary Research Authors: Ashley G. Boyle Source Type: research

Eastern, Western, and Venezuelan Equine Encephalitis and West Nile Viruses
This article describes equine encephalitis viruses with a focus on clinical and public health considerations. (Source: Veterinary Clinics of North America: Equine Practice)
Source: Veterinary Clinics of North America: Equine Practice - February 1, 2023 Category: Veterinary Research Authors: Daniela Luethy Source Type: research

Hendra Virus
Hendra virus (HeV) emerged as a zoonotic pathogen in the 1990s, causing low morbidity but high mortality in humans and horses. Pteropid bats are the natural reservoir of HeV and other important zoonotic viruses such as Nipah and Ebola viruses. Equivac HeV, manufactured by Zoetis (Parkville, Victoria, Australia), is the only commercially available vaccine for horses. There is no commercial vaccine for humans. The epidemiology, clinical features, pathology, diagnosis, management, and prevention of HeV will be reviewed. (Source: Veterinary Clinics of North America: Equine Practice)
Source: Veterinary Clinics of North America: Equine Practice - February 1, 2023 Category: Veterinary Research Authors: Xueli Wang, Jessica C. Wise, Allison J. Stewart Source Type: research

Potomac Horse Fever
Potomac horse fever (PHF) is a common cause of equine colitis in endemic areas. Until recently, the only causative agent known to cause PHF was  Neorickettsia risticii. However, N. findlayensis has been isolated from affected horses. Horses typically become infected upon ingestion of Neorickettsia spp.-infected trematodes within aquatic insects. The most common clinical signs include diarrhea, fever, anorexia, lethargy and colic. The d iagnostic test of choice for PHF is PCR of blood and feces. Tetracyclines remain an effective treatment. Supportive care, including fluid therapy, colloid administration, NSAID and anti...
Source: Veterinary Clinics of North America: Equine Practice - February 1, 2023 Category: Veterinary Research Authors: Sandra D. Taylor Source Type: research

Equine Granulocytic Anaplasmosis
Equine granulocytic anaplasmosis is a clinically significant and common disease of equids that has a broader prevalence than was once thought. The most common clinical signs include high fever and edema, with mild to mderate thrombocytopenia and lymphopenia typically noted on complete blood count. Subclinical cases are reported and many are self-limiting. Rare clinical presentations include neurologic disease, vasculitis, dysphagia, rhabdomyolysis, or bicavitary effusion. Most cases resolve rapidly with appropriate antimicrobial intervention. (Source: Veterinary Clinics of North America: Equine Practice)
Source: Veterinary Clinics of North America: Equine Practice - February 1, 2023 Category: Veterinary Research Authors: Andrea Oliver, Francisco O. Conrado, Rose Nolen-Walston Source Type: research

An Overview of Equine Enteric Clostridial Diseases
The understanding of the pathogenesis of equine enteric clostridial organisms is an active, evolving field. Advances will improve our knowledge both from the animal welfare and human health perspectives. The zoonotic nature of this group of diseases makes them relevant in the age of One health, as a significant amount of close human –equine interactions occurs for business and pleasure. Economic and welfare reasons prompt a better understanding of enteric clostridial pathogenesis, treatment, and control of the infection in horses and ongoing efforts are needed to advance clinical outcomes. (Source: Veterinary Clinics of ...
Source: Veterinary Clinics of North America: Equine Practice - February 1, 2023 Category: Veterinary Research Authors: Deepa Ashwarya Kuttappan, Shankumar Mooyottu, Brett A. Sponseller Source Type: research

Getting Prepared
One constant in veterinary practice is “change,” and in the case of infectious diseases, not only is our understanding of potential pathogens improving—a positive change—but also many features of the pathogens are changing, perhaps posing new clinical challenges. Antimicrobial resistance is an increasingly concerning feature in m anaging bacterial diseases in horses of all ages, including Rhodococcus equi. Dr Sanz provides context for management options, including active surveillance, and reviews considerations in adjunct plasma administration. (Source: Veterinary Clinics of North America: Equine Practice)
Source: Veterinary Clinics of North America: Equine Practice - February 1, 2023 Category: Veterinary Research Authors: Brett A. Sponseller Tags: Preface Source Type: research

Equine Coronaviruses
Coronaviruses are a group of related RNA viruses that cause diseases in mammals and birds. In equids, equine coronavirus has been associated with diarrhea in foals and lethargy, fever, anorexia and occasional gastrointestinal signs in adult horses. The challenge with ECoV infection is recognizing the entity based on clinical and hematological abnormalities and support a diagnosis via molecular detection of coronavirus in feces. There are presently no specific treatment or preventive measures for ECoV infection. While horses appear to be susceptible to the human SARS-CoV-2 based on the high homology to the ACE-2 receptor, t...
Source: Veterinary Clinics of North America: Equine Practice - November 20, 2022 Category: Veterinary Research Authors: Nicola Pusterla Source Type: research

Integrative Medicine
VETERINARY CLINICS OF NORTH AMERICA: EQUINE PRACTICE (Source: Veterinary Clinics of North America: Equine Practice)
Source: Veterinary Clinics of North America: Equine Practice - November 4, 2022 Category: Veterinary Research Authors: Kevin K. Haussler Source Type: research