Is chest imaging needed as part of pT1a renal cell carcinoma surveillance after surgical resection?
CONCLUSION: In patients without baseline preoperative lung pathology, we found that there is questionable clinical value in surveillance for pulmonary recurrence after resection of pT1a RCC.PMID:38040536 | DOI:10.1016/j.urolonc.2023.10.007 (Source: Urologic Oncology)
Source: Urologic Oncology - December 1, 2023 Category: Urology & Nephrology Authors: David Charles John Fitzgerald Truman Landowski Brennen Cooper Raymond Yong Ross Everett William See Kenneth Jacobsohn Scott Johnson Peter Langenstroer Source Type: research
Is chest imaging needed as part of pT1a renal cell carcinoma surveillance after surgical resection?
CONCLUSION: In patients without baseline preoperative lung pathology, we found that there is questionable clinical value in surveillance for pulmonary recurrence after resection of pT1a RCC.PMID:38040536 | DOI:10.1016/j.urolonc.2023.10.007 (Source: Urologic Oncology)
Source: Urologic Oncology - December 1, 2023 Category: Urology & Nephrology Authors: David Charles John Fitzgerald Truman Landowski Brennen Cooper Raymond Yong Ross Everett William See Kenneth Jacobsohn Scott Johnson Peter Langenstroer Source Type: research
Is chest imaging needed as part of pT1a renal cell carcinoma surveillance after surgical resection?
CONCLUSION: In patients without baseline preoperative lung pathology, we found that there is questionable clinical value in surveillance for pulmonary recurrence after resection of pT1a RCC.PMID:38040536 | DOI:10.1016/j.urolonc.2023.10.007 (Source: Urologic Oncology)
Source: Urologic Oncology - December 1, 2023 Category: Urology & Nephrology Authors: David Charles John Fitzgerald Truman Landowski Brennen Cooper Raymond Yong Ross Everett William See Kenneth Jacobsohn Scott Johnson Peter Langenstroer Source Type: research
Is chest imaging needed as part of pT1a renal cell carcinoma surveillance after surgical resection?
CONCLUSION: In patients without baseline preoperative lung pathology, we found that there is questionable clinical value in surveillance for pulmonary recurrence after resection of pT1a RCC.PMID:38040536 | DOI:10.1016/j.urolonc.2023.10.007 (Source: Urologic Oncology)
Source: Urologic Oncology - December 1, 2023 Category: Urology & Nephrology Authors: David Charles John Fitzgerald Truman Landowski Brennen Cooper Raymond Yong Ross Everett William See Kenneth Jacobsohn Scott Johnson Peter Langenstroer Source Type: research
Assessment of Ki-67 proliferation index in prognosis prediction in patients with nonmetastatic clear cell renal cell carcinoma and tumor thrombus
CONCLUSION: The optimal cut-off level of Ki-67 in predicting the prognosis of ccRCC and tumor thrombus was 30%. The high expression of Ki-67 was associated with the aggressive pathological phenotype and poor prognosis.PMID:38030468 | DOI:10.1016/j.urolonc.2023.11.001 (Source: Urologic Oncology)
Source: Urologic Oncology - November 29, 2023 Category: Urology & Nephrology Authors: Jian Zhao Xiaohui Ding Cheng Peng Xia Tian Meifeng Wang Yonggui Fu Huiping Guo Xu Bai Xue Zhai Qingbo Huang Kan Liu Lin Li Huiyi Ye Xu Zhang Xin Ma Haiyi Wang Source Type: research
The bladder microbiota is not significantly altered by intravesical BCG therapy
CONCLUSION: We were unable to identify markers of bladder microbiota dysbiosis among male NMIBC patients. Moreover, we demonstrated for the first time using longitudinally collected samples that BCG cannot persist in the bladder microbiota nor significantly alter its diversity and composition. The associations found between bladder microbes and BCG efficacy highlight the potential of microbial-based therapeutic and risk-stratification strategies in the intermediate/high-risk NMIBC setting.PMID:38030469 | DOI:10.1016/j.urolonc.2023.11.003 (Source: Urologic Oncology)
Source: Urologic Oncology - November 29, 2023 Category: Urology & Nephrology Authors: Vitor Heidrich Antonio C H Mariotti Lilian T Inoue Elisangela M Coser Ernande X Dos Santos Hugo D B Dos Santos Paula F Asprino Fabiana Bettoni Guilherme A P Costa Diogo A Bastos Denis L Jardim Marco A Arap Anamaria A Camargo Source Type: research
Assessment of Ki-67 proliferation index in prognosis prediction in patients with nonmetastatic clear cell renal cell carcinoma and tumor thrombus
CONCLUSION: The optimal cut-off level of Ki-67 in predicting the prognosis of ccRCC and tumor thrombus was 30%. The high expression of Ki-67 was associated with the aggressive pathological phenotype and poor prognosis.PMID:38030468 | DOI:10.1016/j.urolonc.2023.11.001 (Source: Urologic Oncology)
Source: Urologic Oncology - November 29, 2023 Category: Urology & Nephrology Authors: Jian Zhao Xiaohui Ding Cheng Peng Xia Tian Meifeng Wang Yonggui Fu Huiping Guo Xu Bai Xue Zhai Qingbo Huang Kan Liu Lin Li Huiyi Ye Xu Zhang Xin Ma Haiyi Wang Source Type: research
The bladder microbiota is not significantly altered by intravesical BCG therapy
CONCLUSION: We were unable to identify markers of bladder microbiota dysbiosis among male NMIBC patients. Moreover, we demonstrated for the first time using longitudinally collected samples that BCG cannot persist in the bladder microbiota nor significantly alter its diversity and composition. The associations found between bladder microbes and BCG efficacy highlight the potential of microbial-based therapeutic and risk-stratification strategies in the intermediate/high-risk NMIBC setting.PMID:38030469 | DOI:10.1016/j.urolonc.2023.11.003 (Source: Urologic Oncology)
Source: Urologic Oncology - November 29, 2023 Category: Urology & Nephrology Authors: Vitor Heidrich Antonio C H Mariotti Lilian T Inoue Elisangela M Coser Ernande X Dos Santos Hugo D B Dos Santos Paula F Asprino Fabiana Bettoni Guilherme A P Costa Diogo A Bastos Denis L Jardim Marco A Arap Anamaria A Camargo Source Type: research
Patient reported treatment burden and attitudes towards in-home intravesical therapy among patients with bladder cancer
CONCLUSIONS: Bladder cancer patients reported considerable travel distances, time requirements, and need for caregiver support when receiving intravesical therapy. Nearly three-quarters of survey respondents reported openness to receiving intravesical instillations in their home, with many identifying potential benefits for home over clinic-based therapy.PMID:37993341 | DOI:10.1016/j.urolonc.2023.09.006 (Source: Urologic Oncology)
Source: Urologic Oncology - November 22, 2023 Category: Urology & Nephrology Authors: Amanda Myers Benjamin Ristau Matthew Mossanen Mark D Tyson Stephanie Chisolm Frank Sloan Colleen T Ball Angela Smith Timothy D Lyon Source Type: research
Patient reported treatment burden and attitudes towards in-home intravesical therapy among patients with bladder cancer
CONCLUSIONS: Bladder cancer patients reported considerable travel distances, time requirements, and need for caregiver support when receiving intravesical therapy. Nearly three-quarters of survey respondents reported openness to receiving intravesical instillations in their home, with many identifying potential benefits for home over clinic-based therapy.PMID:37993341 | DOI:10.1016/j.urolonc.2023.09.006 (Source: Urologic Oncology)
Source: Urologic Oncology - November 22, 2023 Category: Urology & Nephrology Authors: Amanda Myers Benjamin Ristau Matthew Mossanen Mark D Tyson Stephanie Chisolm Frank Sloan Colleen T Ball Angela Smith Timothy D Lyon Source Type: research
Patient reported treatment burden and attitudes towards in-home intravesical therapy among patients with bladder cancer
CONCLUSIONS: Bladder cancer patients reported considerable travel distances, time requirements, and need for caregiver support when receiving intravesical therapy. Nearly three-quarters of survey respondents reported openness to receiving intravesical instillations in their home, with many identifying potential benefits for home over clinic-based therapy.PMID:37993341 | DOI:10.1016/j.urolonc.2023.09.006 (Source: Urologic Oncology)
Source: Urologic Oncology - November 22, 2023 Category: Urology & Nephrology Authors: Amanda Myers Benjamin Ristau Matthew Mossanen Mark D Tyson Stephanie Chisolm Frank Sloan Colleen T Ball Angela Smith Timothy D Lyon Source Type: research
Patient reported treatment burden and attitudes towards in-home intravesical therapy among patients with bladder cancer
CONCLUSIONS: Bladder cancer patients reported considerable travel distances, time requirements, and need for caregiver support when receiving intravesical therapy. Nearly three-quarters of survey respondents reported openness to receiving intravesical instillations in their home, with many identifying potential benefits for home over clinic-based therapy.PMID:37993341 | DOI:10.1016/j.urolonc.2023.09.006 (Source: Urologic Oncology)
Source: Urologic Oncology - November 22, 2023 Category: Urology & Nephrology Authors: Amanda Myers Benjamin Ristau Matthew Mossanen Mark D Tyson Stephanie Chisolm Frank Sloan Colleen T Ball Angela Smith Timothy D Lyon Source Type: research
Patient reported treatment burden and attitudes towards in-home intravesical therapy among patients with bladder cancer
CONCLUSIONS: Bladder cancer patients reported considerable travel distances, time requirements, and need for caregiver support when receiving intravesical therapy. Nearly three-quarters of survey respondents reported openness to receiving intravesical instillations in their home, with many identifying potential benefits for home over clinic-based therapy.PMID:37993341 | DOI:10.1016/j.urolonc.2023.09.006 (Source: Urologic Oncology)
Source: Urologic Oncology - November 22, 2023 Category: Urology & Nephrology Authors: Amanda Myers Benjamin Ristau Matthew Mossanen Mark D Tyson Stephanie Chisolm Frank Sloan Colleen T Ball Angela Smith Timothy D Lyon Source Type: research
Patient reported treatment burden and attitudes towards in-home intravesical therapy among patients with bladder cancer
CONCLUSIONS: Bladder cancer patients reported considerable travel distances, time requirements, and need for caregiver support when receiving intravesical therapy. Nearly three-quarters of survey respondents reported openness to receiving intravesical instillations in their home, with many identifying potential benefits for home over clinic-based therapy.PMID:37993341 | DOI:10.1016/j.urolonc.2023.09.006 (Source: Urologic Oncology)
Source: Urologic Oncology - November 22, 2023 Category: Urology & Nephrology Authors: Amanda Myers Benjamin Ristau Matthew Mossanen Mark D Tyson Stephanie Chisolm Frank Sloan Colleen T Ball Angela Smith Timothy D Lyon Source Type: research
Molecular mechanism of microRNAs, long noncoding RNAs, and circular RNAs regulating lymphatic metastasis of bladder cancer
Urol Oncol. 2023 Nov 20:S1078-1439(23)00351-4. doi: 10.1016/j.urolonc.2023.10.012. Online ahead of print.ABSTRACTBladder cancer (BC), a malignancy originating in the epithelial tissue in the inner wall of the bladder, is a common urological cancer type. BC spreads through 3 main pathways: direct infiltration, lymphatic metastasis, and hematogenous metastasis. Lymphatic metastasis is considered a poor prognostic factor for BC and is often associated with lower survival rates. The treatment of BC after lymphatic metastasis is complex and challenging. A deeper understanding of the molecular mechanisms underlying lymphatic met...
Source: Urologic Oncology - November 21, 2023 Category: Urology & Nephrology Authors: Wei Zengzhao Lan Xuan Ma Xiaohan Hou Encun Chen Jibing Gao Hongjun Source Type: research
