Antibiotic use reduces the efficacy of immune checkpoint inhibitors in patients with urothelial carcinoma: A systematic review and meta-analysis
CONCLUSIONS: Antibiotic use significantly reduced OS and PFS in UC patients receiving ICI. While antibiotics remain crucial for the treatment of infections in UC patients, antibiotics should be prescribed cautiously in UC patients receiving ICI.PATIENT SUMMARY: Antibiotic use is associated with worsened survival in UC patients receiving immune checkpoint inhibitors.PMID:38101990 | DOI:10.1016/j.urolonc.2023.11.017 (Source: Urologic Oncology)
Source: Urologic Oncology - December 15, 2023 Category: Urology & Nephrology Authors: Toni Febriyanto Fajar Muhammad Wynne Wijaya Oliver Oey Daniel Martin Simadibrata Source Type: research
Exploring the opportunities and challenges of implementing artificial intelligence in healthcare: A systematic literature review
This study aimed to synthesize empirical studies on the challenges and opportunities of using AI by conducting a systematic review. We reviewed 33 articles published between 2015 and 2022 in the PubMed, IEEE Xplore, and Science Direct databases. The results show that artificial intelligence has the promise of improving health care and faces obstacles when implemented. Most of the reviewed studies indicated that the use of AI provides several opportunities, including teamwork and decision-making, technological advancement, diagnosis and patient monitoring, drug development, and virtual health assistance. However, the findin...
Source: Urologic Oncology - December 15, 2023 Category: Urology & Nephrology Authors: Betelhem Zewdu Wubineh Fitsum Gizachew Deriba Michael Melese Woldeyohannis Source Type: research
Contemporary sex-specific analysis of the association of marital status with cancer-specific mortality in primary urethral carcinoma patients
CONCLUSIONS: Married status was associated with lower CSM in PUC patients. However, this benefit applies to female PUC patients, but not to their male counterparts.PMID:38101989 | DOI:10.1016/j.urolonc.2023.10.013 (Source: Urologic Oncology)
Source: Urologic Oncology - December 15, 2023 Category: Urology & Nephrology Authors: Simone Morra Lukas Scheipner Andrea Baudo Letizia Maria Ippolita Jannello Mario de Angelis Carolin Siech Jordan A Goyal Nawar Touma Zhe Tian Fred Saad Massimiliano Creta Gianluigi Califano Giuseppe Celentano Shahrokh F Shariat Sascha Ahyai Luca Carmignani Source Type: research
Antibiotic use reduces the efficacy of immune checkpoint inhibitors in patients with urothelial carcinoma: A systematic review and meta-analysis
CONCLUSIONS: Antibiotic use significantly reduced OS and PFS in UC patients receiving ICI. While antibiotics remain crucial for the treatment of infections in UC patients, antibiotics should be prescribed cautiously in UC patients receiving ICI.PATIENT SUMMARY: Antibiotic use is associated with worsened survival in UC patients receiving immune checkpoint inhibitors.PMID:38101990 | DOI:10.1016/j.urolonc.2023.11.017 (Source: Urologic Oncology)
Source: Urologic Oncology - December 15, 2023 Category: Urology & Nephrology Authors: Toni Febriyanto Fajar Muhammad Wynne Wijaya Oliver Oey Daniel Martin Simadibrata Source Type: research
Exploring the opportunities and challenges of implementing artificial intelligence in healthcare: A systematic literature review
This study aimed to synthesize empirical studies on the challenges and opportunities of using AI by conducting a systematic review. We reviewed 33 articles published between 2015 and 2022 in the PubMed, IEEE Xplore, and Science Direct databases. The results show that artificial intelligence has the promise of improving health care and faces obstacles when implemented. Most of the reviewed studies indicated that the use of AI provides several opportunities, including teamwork and decision-making, technological advancement, diagnosis and patient monitoring, drug development, and virtual health assistance. However, the findin...
Source: Urologic Oncology - December 15, 2023 Category: Urology & Nephrology Authors: Betelhem Zewdu Wubineh Fitsum Gizachew Deriba Michael Melese Woldeyohannis Source Type: research
Real-world progression in the survival of de novo Metastatic prostate cancer over the past decade
CONCLUSION: The survival of mPCa have significantly improved over the past decade, although the progress is slower in elderly patients. Investigating the underlying reasons for survival differences among various patient profiles can further refine mPCa treatment strategies.PMID:38097476 | DOI:10.1016/j.urolonc.2023.11.021 (Source: Urologic Oncology)
Source: Urologic Oncology - December 14, 2023 Category: Urology & Nephrology Authors: Xiaoxiao Guo Haoran Xia Fengbo Zhang Gangyue Hao Source Type: research
Real-world progression in the survival of de novo Metastatic prostate cancer over the past decade
CONCLUSION: The survival of mPCa have significantly improved over the past decade, although the progress is slower in elderly patients. Investigating the underlying reasons for survival differences among various patient profiles can further refine mPCa treatment strategies.PMID:38097476 | DOI:10.1016/j.urolonc.2023.11.021 (Source: Urologic Oncology)
Source: Urologic Oncology - December 14, 2023 Category: Urology & Nephrology Authors: Xiaoxiao Guo Haoran Xia Fengbo Zhang Gangyue Hao Source Type: research
Interruptions in bladder cancer care during the COVID-19 public health emergency
CONCLUSIONS: Bladder cancer care was minimally restricted compared with more pronounced restrictions seen in general elective surgeries during the COVID-19 pandemic.PMID:38087711 | DOI:10.1016/j.urolonc.2023.11.010 (Source: Urologic Oncology)
Source: Urologic Oncology - December 13, 2023 Category: Urology & Nephrology Authors: John L Gore Kristin Follmer Jason Reynolds Michael Nash Christopher B Anderson James W F Catto Karim Chamie Siamak Daneshmand Rian Dickstein Tullika Garg Scott M Gilbert Thomas J Guzzo Ashish M Kamat Max R Kates Brian R Lane Yair Lotan Ahmed M Mansour Vir Source Type: research
Interruptions in bladder cancer care during the COVID-19 public health emergency
CONCLUSIONS: Bladder cancer care was minimally restricted compared with more pronounced restrictions seen in general elective surgeries during the COVID-19 pandemic.PMID:38087711 | DOI:10.1016/j.urolonc.2023.11.010 (Source: Urologic Oncology)
Source: Urologic Oncology - December 13, 2023 Category: Urology & Nephrology Authors: John L Gore Kristin Follmer Jason Reynolds Michael Nash Christopher B Anderson James W F Catto Karim Chamie Siamak Daneshmand Rian Dickstein Tullika Garg Scott M Gilbert Thomas J Guzzo Ashish M Kamat Max R Kates Brian R Lane Yair Lotan Ahmed M Mansour Vir Source Type: research
Higher prevalence of benign tumors in men with testicular tumors and history of treated cryptorchidism
CONCLUSION: Previous studies have shown that there is a greater rate of seminoma in patients with testicular cancer in an undescended testis. This study shows that in patients with a history of UDT compared to those without a history of UDT, there is a greater percentage of patients with benign testicular masses after orchiectomy. Guideline based practices including monthly self-examination and testis-sparing surgery for appropriate patients may reduce rates of radical orchiectomy for benign tumors.PMID:38072736 | DOI:10.1016/j.urolonc.2023.11.016 (Source: Urologic Oncology)
Source: Urologic Oncology - December 10, 2023 Category: Urology & Nephrology Authors: Rachel Davis Alexander M Hirsch Christian C Morrill Ahmad Haffar Mahir Maruf Joseph Cheaib Phillip Pierorazio Heather N Di Carlo Source Type: research
Preoperative C-reactive protein to albumin ratio as a novel prognostic biomarker for the oncological outcomes of radical nephroureterectomy
CONCLUSION: Pre-operative CAR is independently associated with poor PFS and CSS in patients with UTUC undergoing RNU. Moreover, CAR may be an independent UTUC prognostic factor, offering a cost-effective and minimally invasive marker. However, further validation through large-scale, multi-center studies is necessary to confirm these findings and determine the optimal CAR cut-off value.PMID:38072737 | DOI:10.1016/j.urolonc.2023.10.011 (Source: Urologic Oncology)
Source: Urologic Oncology - December 10, 2023 Category: Urology & Nephrology Authors: Chan Hoon Gwak Jungyo Suh Bumjin Lim Cheryn Song Dalsan You In Gab Jeong Jun Hyuk Hong Bumsik Hong Hanjong Ahn Source Type: research
Higher prevalence of benign tumors in men with testicular tumors and history of treated cryptorchidism
CONCLUSION: Previous studies have shown that there is a greater rate of seminoma in patients with testicular cancer in an undescended testis. This study shows that in patients with a history of UDT compared to those without a history of UDT, there is a greater percentage of patients with benign testicular masses after orchiectomy. Guideline based practices including monthly self-examination and testis-sparing surgery for appropriate patients may reduce rates of radical orchiectomy for benign tumors.PMID:38072736 | DOI:10.1016/j.urolonc.2023.11.016 (Source: Urologic Oncology)
Source: Urologic Oncology - December 10, 2023 Category: Urology & Nephrology Authors: Rachel Davis Alexander M Hirsch Christian C Morrill Ahmad Haffar Mahir Maruf Joseph Cheaib Phillip Pierorazio Heather N Di Carlo Source Type: research
Preoperative C-reactive protein to albumin ratio as a novel prognostic biomarker for the oncological outcomes of radical nephroureterectomy
CONCLUSION: Pre-operative CAR is independently associated with poor PFS and CSS in patients with UTUC undergoing RNU. Moreover, CAR may be an independent UTUC prognostic factor, offering a cost-effective and minimally invasive marker. However, further validation through large-scale, multi-center studies is necessary to confirm these findings and determine the optimal CAR cut-off value.PMID:38072737 | DOI:10.1016/j.urolonc.2023.10.011 (Source: Urologic Oncology)
Source: Urologic Oncology - December 10, 2023 Category: Urology & Nephrology Authors: Chan Hoon Gwak Jungyo Suh Bumjin Lim Cheryn Song Dalsan You In Gab Jeong Jun Hyuk Hong Bumsik Hong Hanjong Ahn Source Type: research
Patient-reported prostate cancer treatment regret following primary partial gland cryoablation
CONCLUSIONS: The overwhelming majority of men do not express TRR following PPGCA. The loss of potency or development of erectile dysfunction predisposes to TRR. It is imperative to elucidate short-, intermediate- and long-term functional and oncological outcomes in order to define factors associated with TRR to improve counseling and reduce patient regret.PMID:38065805 | DOI:10.1016/j.urolonc.2023.10.003 (Source: Urologic Oncology)
Source: Urologic Oncology - December 8, 2023 Category: Urology & Nephrology Authors: Herbert Lepor Eli Rapoport Rozalba Gogaj Hunter Hernandez James S Wysock Source Type: research
Patient-reported prostate cancer treatment regret following primary partial gland cryoablation
CONCLUSIONS: The overwhelming majority of men do not express TRR following PPGCA. The loss of potency or development of erectile dysfunction predisposes to TRR. It is imperative to elucidate short-, intermediate- and long-term functional and oncological outcomes in order to define factors associated with TRR to improve counseling and reduce patient regret.PMID:38065805 | DOI:10.1016/j.urolonc.2023.10.003 (Source: Urologic Oncology)
Source: Urologic Oncology - December 8, 2023 Category: Urology & Nephrology Authors: Herbert Lepor Eli Rapoport Rozalba Gogaj Hunter Hernandez James S Wysock Source Type: research
