Antibiotic use reduces the efficacy of immune checkpoint inhibitors in patients with urothelial carcinoma: A systematic review and meta-analysis

CONCLUSIONS: Antibiotic use significantly reduced OS and PFS in UC patients receiving ICI. While antibiotics remain crucial for the treatment of infections in UC patients, antibiotics should be prescribed cautiously in UC patients receiving ICI.PATIENT SUMMARY: Antibiotic use is associated with worsened survival in UC patients receiving immune checkpoint inhibitors.PMID:38101990 | DOI:10.1016/j.urolonc.2023.11.017

Source: Urologic Oncology - December 15, 2023 Category: Urology & Nephrology Authors: Toni Febriyanto Fajar Muhammad Wynne Wijaya Oliver Oey Daniel Martin Simadibrata Source Type: research