Survival impact of variant histology in patients with upper tract urothelial carcinoma after radical nephroureterectomy
CONCLUSION: For UTUC patients after RNU, the presence of VH is associated with aggressive clinicopathological features and inferior survival outcomes. However, the survival outcomes of localized UTUC patients (pT≤2) with VH, and patients with the AD or regional SCD subtype are comparable to those of patients with pUC.PMID:38151426 | DOI:10.1016/j.urolonc.2023.12.006 (Source: Urologic Oncology)
Source: Urologic Oncology - December 27, 2023 Category: Urology & Nephrology Authors: Jianjun Ye Xiaoli Wang Xinyang Liao Zeyu Chen Xingyuan Wang Chichen Zhang Ping Han Qiang Wei Yige Bao Source Type: research

Comparison of aggressiveness in central versus peripheral T1a clear-cell renal cell carcinoma
CONCLUSION: Centrally located kidney cancer has showed in present study a higher incidence of high ISUP grade, regional nodal involvement and endophytic growth type. Endophytic growth type was associated with worse ISUP grading. Distribution of ISUP grade was not age depended, thus showing no difference by this criterion, when comparing different age groups. Higher ISUP grade was strongly associated with presence of distant metastases in T1a kidney tumors. Further analysis is needed to investigate aggressiveness of centrally located T1a RCC, as it may influence current conservative management options.PMID:38151425 | DOI:10...
Source: Urologic Oncology - December 27, 2023 Category: Urology & Nephrology Authors: Sofiya L Semko Oleg A Voylenko Maksym V Pikul Oleksandr E Stakhovskyi Oleksii A Kononenko Iurii V Vitruk Eduard O Stakhovsky Bohdan Hrechko Source Type: research

Survival impact of variant histology in patients with upper tract urothelial carcinoma after radical nephroureterectomy
CONCLUSION: For UTUC patients after RNU, the presence of VH is associated with aggressive clinicopathological features and inferior survival outcomes. However, the survival outcomes of localized UTUC patients (pT≤2) with VH, and patients with the AD or regional SCD subtype are comparable to those of patients with pUC.PMID:38151426 | DOI:10.1016/j.urolonc.2023.12.006 (Source: Urologic Oncology)
Source: Urologic Oncology - December 27, 2023 Category: Urology & Nephrology Authors: Jianjun Ye Xiaoli Wang Xinyang Liao Zeyu Chen Xingyuan Wang Chichen Zhang Ping Han Qiang Wei Yige Bao Source Type: research

Comparison of aggressiveness in central versus peripheral T1a clear-cell renal cell carcinoma
CONCLUSION: Centrally located kidney cancer has showed in present study a higher incidence of high ISUP grade, regional nodal involvement and endophytic growth type. Endophytic growth type was associated with worse ISUP grading. Distribution of ISUP grade was not age depended, thus showing no difference by this criterion, when comparing different age groups. Higher ISUP grade was strongly associated with presence of distant metastases in T1a kidney tumors. Further analysis is needed to investigate aggressiveness of centrally located T1a RCC, as it may influence current conservative management options.PMID:38151425 | DOI:10...
Source: Urologic Oncology - December 27, 2023 Category: Urology & Nephrology Authors: Sofiya L Semko Oleg A Voylenko Maksym V Pikul Oleksandr E Stakhovskyi Oleksii A Kononenko Iurii V Vitruk Eduard O Stakhovsky Bohdan Hrechko Source Type: research

Survival impact of variant histology in patients with upper tract urothelial carcinoma after radical nephroureterectomy
CONCLUSION: For UTUC patients after RNU, the presence of VH is associated with aggressive clinicopathological features and inferior survival outcomes. However, the survival outcomes of localized UTUC patients (pT≤2) with VH, and patients with the AD or regional SCD subtype are comparable to those of patients with pUC.PMID:38151426 | DOI:10.1016/j.urolonc.2023.12.006 (Source: Urologic Oncology)
Source: Urologic Oncology - December 27, 2023 Category: Urology & Nephrology Authors: Jianjun Ye Xiaoli Wang Xinyang Liao Zeyu Chen Xingyuan Wang Chichen Zhang Ping Han Qiang Wei Yige Bao Source Type: research

Functional recovery after partial nephrectomy in a solitary kidney
CONCLUSION: The main determinant of functional recovery after PN in RMSK is parenchymal volume preservation. Type/duration of ischemia, AKI, and age also correlated, although altogether their contributions were less impactful. Our findings suggest multiple opportunities for optimizing functional outcomes although preservation of parenchymal volume remains predominant. Long-term function generally remains stable with dialysis only occasionally required.PMID:38142208 | DOI:10.1016/j.urolonc.2023.12.004 (Source: Urologic Oncology)
Source: Urologic Oncology - December 23, 2023 Category: Urology & Nephrology Authors: Worapat Attawettayanon Yosuke Yasuda Jj H Zhang Nityam Rathi Carlos Munoz-Lopez Akira Kazama Kieran Lewis Ben Ponvilawan Snehi Shah Andrew Wood Jianbo Li Jo ão Pedro Emrich Accioly Rebecca A Campbell Joseph Zabell Jihad Kaouk Georges-Pascal Haber Mohamad Source Type: research

AI-powered real-time annotations during urologic surgery: The future of training and quality metrics
CONCLUSIONS: For the first time, surgical intelligence successfully showcased real-time AI annotations of 2 separate urologic robotic procedures during a live telecast. These annotations may provide the technological framework for send automatic notifications to clinical or operational stakeholders. This technology is a first step in real-time intraoperative decision support, leveraging big data to improve the quality of surgical care, potentially improve surgical outcomes, and support training and education.PMID:38142209 | DOI:10.1016/j.urolonc.2023.11.002 (Source: Urologic Oncology)
Source: Urologic Oncology - December 23, 2023 Category: Urology & Nephrology Authors: Laura Zuluaga Jordan Miller Rich Raghav Gupta Adriana Pedraza Burak Ucpinar Kennedy E Okhawere Indu Saini Priyanka Dwivedi Dhruti Patel Osama Zaytoun Mani Menon Ashutosh Tewari Ketan K Badani Source Type: research

Functional recovery after partial nephrectomy in a solitary kidney
CONCLUSION: The main determinant of functional recovery after PN in RMSK is parenchymal volume preservation. Type/duration of ischemia, AKI, and age also correlated, although altogether their contributions were less impactful. Our findings suggest multiple opportunities for optimizing functional outcomes although preservation of parenchymal volume remains predominant. Long-term function generally remains stable with dialysis only occasionally required.PMID:38142208 | DOI:10.1016/j.urolonc.2023.12.004 (Source: Urologic Oncology)
Source: Urologic Oncology - December 23, 2023 Category: Urology & Nephrology Authors: Worapat Attawettayanon Yosuke Yasuda Jj H Zhang Nityam Rathi Carlos Munoz-Lopez Akira Kazama Kieran Lewis Ben Ponvilawan Snehi Shah Andrew Wood Jianbo Li Jo ão Pedro Emrich Accioly Rebecca A Campbell Joseph Zabell Jihad Kaouk Georges-Pascal Haber Mohamad Source Type: research

AI-powered real-time annotations during urologic surgery: The future of training and quality metrics
CONCLUSIONS: For the first time, surgical intelligence successfully showcased real-time AI annotations of 2 separate urologic robotic procedures during a live telecast. These annotations may provide the technological framework for send automatic notifications to clinical or operational stakeholders. This technology is a first step in real-time intraoperative decision support, leveraging big data to improve the quality of surgical care, potentially improve surgical outcomes, and support training and education.PMID:38142209 | DOI:10.1016/j.urolonc.2023.11.002 (Source: Urologic Oncology)
Source: Urologic Oncology - December 23, 2023 Category: Urology & Nephrology Authors: Laura Zuluaga Jordan Miller Rich Raghav Gupta Adriana Pedraza Burak Ucpinar Kennedy E Okhawere Indu Saini Priyanka Dwivedi Dhruti Patel Osama Zaytoun Mani Menon Ashutosh Tewari Ketan K Badani Source Type: research

Functional recovery after partial nephrectomy in a solitary kidney
CONCLUSION: The main determinant of functional recovery after PN in RMSK is parenchymal volume preservation. Type/duration of ischemia, AKI, and age also correlated, although altogether their contributions were less impactful. Our findings suggest multiple opportunities for optimizing functional outcomes although preservation of parenchymal volume remains predominant. Long-term function generally remains stable with dialysis only occasionally required.PMID:38142208 | DOI:10.1016/j.urolonc.2023.12.004 (Source: Urologic Oncology)
Source: Urologic Oncology - December 23, 2023 Category: Urology & Nephrology Authors: Worapat Attawettayanon Yosuke Yasuda Jj H Zhang Nityam Rathi Carlos Munoz-Lopez Akira Kazama Kieran Lewis Ben Ponvilawan Snehi Shah Andrew Wood Jianbo Li Jo ão Pedro Emrich Accioly Rebecca A Campbell Joseph Zabell Jihad Kaouk Georges-Pascal Haber Mohamad Source Type: research

AI-powered real-time annotations during urologic surgery: The future of training and quality metrics
CONCLUSIONS: For the first time, surgical intelligence successfully showcased real-time AI annotations of 2 separate urologic robotic procedures during a live telecast. These annotations may provide the technological framework for send automatic notifications to clinical or operational stakeholders. This technology is a first step in real-time intraoperative decision support, leveraging big data to improve the quality of surgical care, potentially improve surgical outcomes, and support training and education.PMID:38142209 | DOI:10.1016/j.urolonc.2023.11.002 (Source: Urologic Oncology)
Source: Urologic Oncology - December 23, 2023 Category: Urology & Nephrology Authors: Laura Zuluaga Jordan Miller Rich Raghav Gupta Adriana Pedraza Burak Ucpinar Kennedy E Okhawere Indu Saini Priyanka Dwivedi Dhruti Patel Osama Zaytoun Mani Menon Ashutosh Tewari Ketan K Badani Source Type: research

Editors in transition
Urol Oncol. 2024 Jan;42(1):1-2. doi: 10.1016/j.urolonc.2023.11.011.NO ABSTRACTPMID:38135357 | DOI:10.1016/j.urolonc.2023.11.011 (Source: Urologic Oncology)
Source: Urologic Oncology - December 22, 2023 Category: Urology & Nephrology Authors: Michael J Droller Source Type: research

Oncologic outcomes of intravesical therapy in the management of nonmuscle invasive bladder cancer with variant histology
CONCLUSION: In this series of highly-selected patients with NMIBC and VH, bladder-sparing treatment with intravesical therapy demonstrated acceptable oncologic outcomes for most VHs. This may be an acceptable treatment option for patients without plasmacytoid, sarcomatoid, or micropapillary features who are not suitable cystectomy candidates or who prioritize bladder-sparing treatment.PMID:38135626 | DOI:10.1016/j.urolonc.2023.12.005 (Source: Urologic Oncology)
Source: Urologic Oncology - December 22, 2023 Category: Urology & Nephrology Authors: Zaeem Lone Tarik Benidir Andrew Wood Rebecca A Campbell Reza Alaghehbandan Jianbo Li Georges-Pascal Haber Mohammed Eltemamy Samuel C Haywood Christopher J Weight Byron H Lee Nima Almassi Source Type: research

Surgical outcomes of cytoreductive nephrectomy in patients receiving systemic immunotherapy for advanced renal cell carcinoma
CONCLUSION: In our cohort, there was no significant difference in surgical complications among patients who received systemic therapy before surgery compared to those who did not receive upfront systemic therapy. Cytoreductive nephrectomy is safe and with low rates of complications following the use of systemic therapy.PMID:38135627 | DOI:10.1016/j.urolonc.2023.12.003 (Source: Urologic Oncology)
Source: Urologic Oncology - December 22, 2023 Category: Urology & Nephrology Authors: Stephen W Reese Lennert Eismann Charlie White Juan Arroyave Villada Sari Khaleel Irina Ostrovnaya Katiana Vazquez-Rivera Maria I Carlo Darren Feldman Chung-Han Lee Robert Motzer Martin H Voss Ritesh R Kotecha Richard S Matulewicz Alvin Goh Jonathan Colema Source Type: research

Editors in transition
Urol Oncol. 2024 Jan;42(1):1-2. doi: 10.1016/j.urolonc.2023.11.011.NO ABSTRACTPMID:38135357 | DOI:10.1016/j.urolonc.2023.11.011 (Source: Urologic Oncology)
Source: Urologic Oncology - December 22, 2023 Category: Urology & Nephrology Authors: Michael J Droller Source Type: research