Comparison of aggressiveness in central versus peripheral T1a clear-cell renal cell carcinoma

CONCLUSION: Centrally located kidney cancer has showed in present study a higher incidence of high ISUP grade, regional nodal involvement and endophytic growth type. Endophytic growth type was associated with worse ISUP grading. Distribution of ISUP grade was not age depended, thus showing no difference by this criterion, when comparing different age groups. Higher ISUP grade was strongly associated with presence of distant metastases in T1a kidney tumors. Further analysis is needed to investigate aggressiveness of centrally located T1a RCC, as it may influence current conservative management options.PMID:38151425 | DOI:10.1016/j.urolonc.2023.11.014

Source: Urologic Oncology - December 27, 2023 Category: Urology & Nephrology Authors: Sofiya L Semko Oleg A Voylenko Maksym V Pikul Oleksandr E Stakhovskyi Oleksii A Kononenko Iurii V Vitruk Eduard O Stakhovsky Bohdan Hrechko Source Type: research