PROT < sub > 3 < /sub > EcT, engineered Escherichia coli for the targeted delivery of therapeutics
Trends Mol Med. 2023 Aug 11:S1471-4914(23)00157-0. doi: 10.1016/j.molmed.2023.07.007. Online ahead of print.NO ABSTRACTPMID:37574350 | DOI:10.1016/j.molmed.2023.07.007 (Source: Trends in Molecular Medicine)
Source: Trends in Molecular Medicine - August 13, 2023 Category: Molecular Biology Authors: Coral Gonz ález-Prieto Jason P Lynch Cammie F Lesser Source Type: research
PROT < sub > 3 < /sub > EcT, engineered Escherichia coli for the targeted delivery of therapeutics
Trends Mol Med. 2023 Aug 11:S1471-4914(23)00157-0. doi: 10.1016/j.molmed.2023.07.007. Online ahead of print.NO ABSTRACTPMID:37574350 | DOI:10.1016/j.molmed.2023.07.007 (Source: Trends in Molecular Medicine)
Source: Trends in Molecular Medicine - August 13, 2023 Category: Molecular Biology Authors: Coral Gonz ález-Prieto Jason P Lynch Cammie F Lesser Source Type: research
PROT < sub > 3 < /sub > EcT, engineered Escherichia coli for the targeted delivery of therapeutics
Trends Mol Med. 2023 Aug 11:S1471-4914(23)00157-0. doi: 10.1016/j.molmed.2023.07.007. Online ahead of print.NO ABSTRACTPMID:37574350 | DOI:10.1016/j.molmed.2023.07.007 (Source: Trends in Molecular Medicine)
Source: Trends in Molecular Medicine - August 13, 2023 Category: Molecular Biology Authors: Coral Gonz ález-Prieto Jason P Lynch Cammie F Lesser Source Type: research
The NRF2/Keap1 pathway as a therapeutic target in inflammatory bowel disease
Trends Mol Med. 2023 Aug 7:S1471-4914(23)00158-2. doi: 10.1016/j.molmed.2023.07.008. Online ahead of print.ABSTRACTOxidative stress (OS) is an important pathophysiological mechanism in inflammatory bowel disease (IBD). However, clinical trials investigating compounds directly targeting OS in IBD yielded mixed results. The NRF2 (nuclear factor erythroid 2-related factor 2)/Keap1 (Kelch-like ECH-associated protein 1) pathway orchestrates cellular responses to OS, and dysregulation of this pathway has been implicated in IBD. Activation of the NRF2/Keap1 pathway may enhance antioxidant responses. Although this approach could h...
Source: Trends in Molecular Medicine - August 9, 2023 Category: Molecular Biology Authors: Sem Geertsema Arno R Bourgonje Raphael R Fagundes Ranko Gacesa Rinse K Weersma Harry van Goor Giovanni E Mann Gerard Dijkstra Klaas N Faber Source Type: research
The NRF2/Keap1 pathway as a therapeutic target in inflammatory bowel disease
Trends Mol Med. 2023 Aug 7:S1471-4914(23)00158-2. doi: 10.1016/j.molmed.2023.07.008. Online ahead of print.ABSTRACTOxidative stress (OS) is an important pathophysiological mechanism in inflammatory bowel disease (IBD). However, clinical trials investigating compounds directly targeting OS in IBD yielded mixed results. The NRF2 (nuclear factor erythroid 2-related factor 2)/Keap1 (Kelch-like ECH-associated protein 1) pathway orchestrates cellular responses to OS, and dysregulation of this pathway has been implicated in IBD. Activation of the NRF2/Keap1 pathway may enhance antioxidant responses. Although this approach could h...
Source: Trends in Molecular Medicine - August 9, 2023 Category: Molecular Biology Authors: Sem Geertsema Arno R Bourgonje Raphael R Fagundes Ranko Gacesa Rinse K Weersma Harry van Goor Giovanni E Mann Gerard Dijkstra Klaas N Faber Source Type: research
