Multi-omic genetic scores advance disease research
Trends Genet. 2023 Jun 7:S0168-9525(23)00125-7. doi: 10.1016/j.tig.2023.05.002. Online ahead of print.ABSTRACTMulti-omic analysis is an effective approach for dissecting the mechanisms of diseases; however, collecting multi-omic data in large populations is time-consuming and costly. Recently, Xu et al. developed genetic scores for multi-omic traits and demonstrated their utilization to gain novel insights, advancing the application of multi-omic data in disease research.PMID:37295977 | DOI:10.1016/j.tig.2023.05.002 (Source: Trends in Genetics : TIG)
Source: Trends in Genetics : TIG - June 9, 2023 Category: Genetics & Stem Cells Authors: Chengxuan Chen Leng Han Source Type: research
X chromosome enhances NK cell responses
Trends Genet. 2023 Jun 8:S0168-9525(23)00126-9. doi: 10.1016/j.tig.2023.05.003. Online ahead of print.ABSTRACTIncomplete X-chromosome inactivation (XCI) can cause differences between sexes. Cheng et al. identified that the histone demethylase UTX, encoded by an X chromosome gene that escapes XCI, contributes to sex differences in natural killer (NK) cells, whereby males have increased NK cell numbers while female NK cells have enhanced responsiveness.PMID:37295976 | DOI:10.1016/j.tig.2023.05.003 (Source: Trends in Genetics : TIG)
Source: Trends in Genetics : TIG - June 9, 2023 Category: Genetics & Stem Cells Authors: Oscar A Aguilar Source Type: research
Multi-omic genetic scores advance disease research
Trends Genet. 2023 Jun 7:S0168-9525(23)00125-7. doi: 10.1016/j.tig.2023.05.002. Online ahead of print.ABSTRACTMulti-omic analysis is an effective approach for dissecting the mechanisms of diseases; however, collecting multi-omic data in large populations is time-consuming and costly. Recently, Xu et al. developed genetic scores for multi-omic traits and demonstrated their utilization to gain novel insights, advancing the application of multi-omic data in disease research.PMID:37295977 | DOI:10.1016/j.tig.2023.05.002 (Source: Trends in Genetics : TIG)
Source: Trends in Genetics : TIG - June 9, 2023 Category: Genetics & Stem Cells Authors: Chengxuan Chen Leng Han Source Type: research
X chromosome enhances NK cell responses
Trends Genet. 2023 Jun 8:S0168-9525(23)00126-9. doi: 10.1016/j.tig.2023.05.003. Online ahead of print.ABSTRACTIncomplete X-chromosome inactivation (XCI) can cause differences between sexes. Cheng et al. identified that the histone demethylase UTX, encoded by an X chromosome gene that escapes XCI, contributes to sex differences in natural killer (NK) cells, whereby males have increased NK cell numbers while female NK cells have enhanced responsiveness.PMID:37295976 | DOI:10.1016/j.tig.2023.05.003 (Source: Trends in Genetics : TIG)
Source: Trends in Genetics : TIG - June 9, 2023 Category: Genetics & Stem Cells Authors: Oscar A Aguilar Source Type: research
Multi-omic genetic scores advance disease research
Trends Genet. 2023 Jun 7:S0168-9525(23)00125-7. doi: 10.1016/j.tig.2023.05.002. Online ahead of print.ABSTRACTMulti-omic analysis is an effective approach for dissecting the mechanisms of diseases; however, collecting multi-omic data in large populations is time-consuming and costly. Recently, Xu et al. developed genetic scores for multi-omic traits and demonstrated their utilization to gain novel insights, advancing the application of multi-omic data in disease research.PMID:37295977 | DOI:10.1016/j.tig.2023.05.002 (Source: Trends in Genetics : TIG)
Source: Trends in Genetics : TIG - June 9, 2023 Category: Genetics & Stem Cells Authors: Chengxuan Chen Leng Han Source Type: research
