Survivorship and food consumption of immatures and adults of Apis mellifera and Scaptotrigona bipunctata exposed to genetically modified eucalyptus pollen
Transgenic Res. 2023 Apr 7. doi: 10.1007/s11248-023-00343-z. Online ahead of print.ABSTRACTEucalyptus comprises the largest planted area of cultivated production forest in Brazil. Genetic modification (GM) of eucalyptus can provide additional characteristics for increasing productivity and protecting wood yield, as well as potentially altering fiber for a diversity of industrial uses. However, prior to releasing a new GM plant, risk assessments studies with non-target organisms must be undertaken. Bees are prominent biological models since they play an important role in varied ecosystems, including for Eucalyptus pollinati...
Source: Transgenic Research - April 7, 2023 Category: Genetics & Stem Cells Authors: Charles F Dos Santos Jenifer D Ramos Fernanda G de Carvalho Andressa L Dorneles Thais R D Menezes Ana Cristina Pinheiro Betina Blochtein Source Type: research

Survivorship and food consumption of immatures and adults of Apis mellifera and Scaptotrigona bipunctata exposed to genetically modified eucalyptus pollen
Transgenic Res. 2023 Apr 7. doi: 10.1007/s11248-023-00343-z. Online ahead of print.ABSTRACTEucalyptus comprises the largest planted area of cultivated production forest in Brazil. Genetic modification (GM) of eucalyptus can provide additional characteristics for increasing productivity and protecting wood yield, as well as potentially altering fiber for a diversity of industrial uses. However, prior to releasing a new GM plant, risk assessments studies with non-target organisms must be undertaken. Bees are prominent biological models since they play an important role in varied ecosystems, including for Eucalyptus pollinati...
Source: Transgenic Research - April 7, 2023 Category: Genetics & Stem Cells Authors: Charles F Dos Santos Jenifer D Ramos Fernanda G de Carvalho Andressa L Dorneles Thais R D Menezes Ana Cristina Pinheiro Betina Blochtein Source Type: research

Survivorship and food consumption of immatures and adults of Apis mellifera and Scaptotrigona bipunctata exposed to genetically modified eucalyptus pollen
Transgenic Res. 2023 Apr 7. doi: 10.1007/s11248-023-00343-z. Online ahead of print.ABSTRACTEucalyptus comprises the largest planted area of cultivated production forest in Brazil. Genetic modification (GM) of eucalyptus can provide additional characteristics for increasing productivity and protecting wood yield, as well as potentially altering fiber for a diversity of industrial uses. However, prior to releasing a new GM plant, risk assessments studies with non-target organisms must be undertaken. Bees are prominent biological models since they play an important role in varied ecosystems, including for Eucalyptus pollinati...
Source: Transgenic Research - April 7, 2023 Category: Genetics & Stem Cells Authors: Charles F Dos Santos Jenifer D Ramos Fernanda G de Carvalho Andressa L Dorneles Thais R D Menezes Ana Cristina Pinheiro Betina Blochtein Source Type: research

Survivorship and food consumption of immatures and adults of Apis mellifera and Scaptotrigona bipunctata exposed to genetically modified eucalyptus pollen
Transgenic Res. 2023 Apr 7. doi: 10.1007/s11248-023-00343-z. Online ahead of print.ABSTRACTEucalyptus comprises the largest planted area of cultivated production forest in Brazil. Genetic modification (GM) of eucalyptus can provide additional characteristics for increasing productivity and protecting wood yield, as well as potentially altering fiber for a diversity of industrial uses. However, prior to releasing a new GM plant, risk assessments studies with non-target organisms must be undertaken. Bees are prominent biological models since they play an important role in varied ecosystems, including for Eucalyptus pollinati...
Source: Transgenic Research - April 7, 2023 Category: Genetics & Stem Cells Authors: Charles F Dos Santos Jenifer D Ramos Fernanda G de Carvalho Andressa L Dorneles Thais R D Menezes Ana Cristina Pinheiro Betina Blochtein Source Type: research

Plant-based production of an orally active cyclotide for the treatment of multiple sclerosis
In this study, we demonstrate the capacity of the Australian native Nicotiana benthamiana plant to produce a structurally identical [T20K]kB1 to that of the synthetic peptide. By optimizing the co-expressed cyclizing enzyme, precursor peptide arrangements, and transgene regulatory regions, we demonstrate a [T20K]kB1 yield in crude peptide extracts of ~ 0.3 mg/g dry mass) in whole plants and close to 1.0 mg/g dry mass in isolated infiltrated leaves. With large-scale plant production facilities coming on-line across the world, the sustainable and cost-effective production of cyclotide-based therapeutics is now within reach.P...
Source: Transgenic Research - March 17, 2023 Category: Genetics & Stem Cells Authors: Mark A Jackson Jing Xie Linh T T Nguyen Xiaohan Wang Kuok Yap Peta J Harvey Edward K Gilding David J Craik Source Type: research