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Correspondence: Interpreting live birth rates following preimplantation genetic testing for aneuploidy: per embryo transferred or initiated cycle
Syst Biol Reprod Med. 2023 Oct 9:1-2. doi: 10.1080/19396368.2023.2261590. Online ahead of print.NO ABSTRACTPMID:37812746 | DOI:10.1080/19396368.2023.2261590 (Source: Systems Biology in Reproductive Medicine)
Source: Systems Biology in Reproductive Medicine - October 9, 2023 Category: Reproduction Medicine Authors: Pedro Augusto Ara újo Monteleone Tatiana Carvalho de Souza Bonetti Source Type: research

MEHP activates JNK to inhibit the migration of human foreskin fibroblasts
This study aimed to investigate the impact of mono(2-ethylhexyl) phthalate (MEHP) on the proliferation, apoptosis, and migration of human foreskin fibroblast cells (HFF-1) and the role of the JNK signaling pathway in cell migration. HFF-1 cells were randomly assigned to the control group with 0 MEHP exposure (M0) or the experimental groups with 25, 50, 100, 200, and 400 μmol/L MEHP exposure (M25, M50, M100, M200, and M400, respectively). After 24 and 48 h of MEHP exposure, the proliferation of HFF-1 cells in any group had no significant change. However, compared with the M0 group, the M200 and M400 groups presented substa...
Source: Systems Biology in Reproductive Medicine - October 9, 2023 Category: Reproduction Medicine Authors: Hu Zhang Xuan Yi Wei Hu Guoqiang Zhu Xiaowen Fu Wei Jin Long Qin Mingyong Li Source Type: research

Polyamines modulate mouse sperm motility
Syst Biol Reprod Med. 2023 Oct 9:1-15. doi: 10.1080/19396368.2023.2262714. Online ahead of print.ABSTRACTPolyamines are polycationic molecules which contains two or more amino groups (-NH3+) highly charged at physiological pH, and among them we found spermine, spermidine, putrescine, and cadaverine. They interact with proteins, nucleic acids, modulate Ca2+, K+, and Na+ channels, and protect sperm from oxidative stress. In this work, we evaluate the effect of spermine, spermidine, and putrescine on the total, progressive and kinematic parameters of motility, capacitation, acrosome reaction, also in presence and absence of t...
Source: Systems Biology in Reproductive Medicine - October 9, 2023 Category: Reproduction Medicine Authors: Lorena Rodr íguez-Páez Charmina Aguirre-Alvarado Germ án Chamorro-Cevallos Alc ántara-Farfán Veronica Calder ón-Espinosa Sandra Irel Castillo-P érez Hugo Carlos Armando Garc ía-Pérez Guadalupe Elizabeth Jim énez-Gutiérrez Joaqu ín Cordero-Mart Source Type: research

Correspondence: Interpreting live birth rates following preimplantation genetic testing for aneuploidy: per embryo transferred or initiated cycle*
. (Source: Systems Biology in Reproductive Medicine)
Source: Systems Biology in Reproductive Medicine - October 9, 2023 Category: Sexual Medicine Authors: Pedro Augusto Ara újo MonteleoneTatiana Carvalho de Souza Bonettia Centro de Reprodução Humana Monteleone Rua Lima Barros, 62, Jardim Paulista, São Paulo, SP, Brasilb Centro de Reprodução Humana Mario Covas, Disciplina de Ginecologia, Departamento d Source Type: research

Polyamines modulate mouse sperm motility
. (Source: Systems Biology in Reproductive Medicine)
Source: Systems Biology in Reproductive Medicine - October 9, 2023 Category: Sexual Medicine Authors: Lorena Rodr íguez-PáezCharmina Aguirre-AlvaradoGermán Chamorro-CevallosAlcántara-Farfán VeronicaCalderón-Espinosa Sandra IrelCastillo-Pérez HugoCarlos Armando García-PérezGuadalupe Elizabeth Jiménez-GutiérrezJoaquín Cordero-Martíneza Laborato Source Type: research

MEHP activates JNK to inhibit the migration of human foreskin fibroblasts
. (Source: Systems Biology in Reproductive Medicine)
Source: Systems Biology in Reproductive Medicine - October 9, 2023 Category: Sexual Medicine Authors: Hu ZhangXuan YiWei HuGuoqiang ZhuXiaowen FuWei JinLong QinMingyong LiUrology Department, The First Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, Hunan Province, China Source Type: research

Response to Correspondence re: Live birth per embryo transfer with next generation sequencing preimplantation genetic testing: an analysis of 26,107 cycles
Syst Biol Reprod Med. 2023 Oct 2:1-2. doi: 10.1080/19396368.2023.2261587. Online ahead of print.NO ABSTRACTPMID:37782559 | DOI:10.1080/19396368.2023.2261587 (Source: Systems Biology in Reproductive Medicine)
Source: Systems Biology in Reproductive Medicine - October 2, 2023 Category: Reproduction Medicine Authors: Papri Sarkar Anthony N Imudia Source Type: research

Identification of ferroptotic genes and phenotypes in idiopathic nonobstructive azoospermia
Syst Biol Reprod Med. 2023 Oct 2:1-13. doi: 10.1080/19396368.2023.2257352. Online ahead of print.ABSTRACTEffective treatments for nonobstructive azoospermia (NOA), which affects 1% of all men globally, are limited by undefined pathogenic mechanisms, especially in idiopathic NOA (iNOA). Here, we tried to identify the functional ferroptosis-related genes and phenotypes involved in iNOA. Differentially expressed ferroptotic genes were identified from iNOA mRNA microarray datasets by bioinformatic analyses, and these ferroptotic genes were subsequently filtered by various algorithms. Then, receiver operating characteristic (RO...
Source: Systems Biology in Reproductive Medicine - October 2, 2023 Category: Reproduction Medicine Authors: Chen Liao Tian-Wen Peng Xiao-Min Li Zhi-Cong Chen Mu-Ye Wang Xin Ye Yu Lan Xin Fu Geng An Source Type: research