Regulatory T cells improve pregnancy rate in RIF patients after additional IVIG treatment
. (Source: Systems Biology in Reproductive Medicine)
Source: Systems Biology in Reproductive Medicine - November 3, 2017 Category: Sexual Medicine Authors: Majid Ahmadi Samaneh Abdolmohammadi-Vahid Mahnaz Ghaebi Leili Aghebati-Maleki Sanam Dolati Laya Farzadi Aliyeh Ghasemzadeh Kobra Hamdi Vahid Younesi Mohammad Nouri Mehdi Yousefi Source Type: research

Insulin resistance in patients with recurrent pregnancy loss is associated with lymphocyte population aberration
Volume 63, Issue 6, December 2017, Page 397-404 . (Source: Systems Biology in Reproductive Medicine)
Source: Systems Biology in Reproductive Medicine - October 31, 2017 Category: Sexual Medicine Authors: Yan Yan Shihua Bao Shile Sheng Liuliu Wang Weiyan Tu Source Type: research

Insulin resistance in patients with recurrent pregnancy loss is associated with lymphocyte population aberration.
This study was designed to investigate the relationship of insulin resistance (IR) and cellular immune abnormalities associated with women with recurrent pregnancy loss (RPL). Women with RPL were divided into two groups according to their homeostasis model assessment for IR (HOMA-IR) scores. The IR group received metformin approximately 3 months before pregnancy. The percentage of lymphocyte subsets and other blood biochemical indices were tested. The HOMA-IR and fasting serum insulin levels were related to the percentage of lymphocyte subsets. The women with RPL had higher CD3(+) and CD3(+)CD4(+) cell levels while CD56(+)...
Source: Systems Biology in Reproductive Medicine - October 31, 2017 Category: Reproduction Medicine Authors: Yan Y, Bao S, Sheng S, Wang L, Tu W Tags: Syst Biol Reprod Med Source Type: research

Insulin resistance in patients with recurrent pregnancy loss is associated with lymphocyte population aberration
. (Source: Systems Biology in Reproductive Medicine)
Source: Systems Biology in Reproductive Medicine - October 31, 2017 Category: Sexual Medicine Authors: Yan Yan Shihua Bao Shile Sheng Liuliu Wang Weiyan Tu Source Type: research

Tri-nucleotide consortium of androgen receptor is associated with low serum FSH and testosterone in asthenospermic men
. (Source: Systems Biology in Reproductive Medicine)
Source: Systems Biology in Reproductive Medicine - October 30, 2017 Category: Sexual Medicine Authors: Haroon Latif Khan Shahzad Bhatti Sana Abbas Yousaf Latif Khan Muhammad Aslamkhan Rosa Maria Marquez Gonzalez Gerardo Rodriguez Gonzalez Hikmet Hakan Aydin Magali Segundo Trinidad Source Type: research

Donor sperm insemination after failed intra-couple intracytoplasmic sperm injection
. (Source: Systems Biology in Reproductive Medicine)
Source: Systems Biology in Reproductive Medicine - October 11, 2017 Category: Sexual Medicine Authors: Sylviane Hennebicq Oxana Blagosklonov Florence Eustache Aline Papaxanthos Veronique Drouineaud Catherine Guillemain Sophie Mirallie Beatrice Delepine Nathalie Rives Isabelle Berthaut Cynthia Frapsauce Jean-Fran çois Guérin Mehdi Benchaib Source Type: research

Donor sperm insemination after failed intra-couple intracytoplasmic sperm injection.
In conclusion, the transition to the AID procedure after intra-conjugal ICSI failure allows such couples to obtain a pregnancy, however after each ART failure AID transition should be proposed according to the woman's age and sperm characteristics. ABBREVIATIONS: AID: artificial insemination with donor sperm; ICSI: intracytoplasmic sperm injection; CECOS: Centre d'Etude et de Conservation des Oeufs et du Sperme; OAT: oligoasthenoteratozoospermia; IVF: in vitro fertilization; ART: artificial reproductive technology; β hCG: beta human chorionic gonadotrophin; SD: standard deviation; OR: Odds ratio. PMID: 29020...
Source: Systems Biology in Reproductive Medicine - October 11, 2017 Category: Reproduction Medicine Authors: Hennebicq S, Blagosklonov O, Eustache F, Papaxanthos A, Drouineaud V, Guillemain C, Mirallie S, Delepine B, Rives N, Berthaut I, Frapsauce C, Guérin JF, Benchaib M Tags: Syst Biol Reprod Med Source Type: research

Donor sperm insemination after failed intra-couple intracytoplasmic sperm injection
. (Source: Systems Biology in Reproductive Medicine)
Source: Systems Biology in Reproductive Medicine - October 11, 2017 Category: Sexual Medicine Authors: Sylviane Hennebicq Oxana Blagosklonov Florence Eustache Aline Papaxanthos Veronique Drouineaud Catherine Guillemain Sophie Mirallie Beatrice Delepine Nathalie Rives Isabelle Berthaut Cynthia Frapsauce Jean-Fran çois Guérin Mehdi Benchaib Source Type: research

Polymorphisms of DNA repair genes XRCC1 and LIG4 and idiopathic male infertility
Volume 63, Issue 6, December 2017, Page 382-390 . (Source: Systems Biology in Reproductive Medicine)
Source: Systems Biology in Reproductive Medicine - October 9, 2017 Category: Sexual Medicine Authors: Hadi Ghasemi Iraj Khodadadi Amir Fattahi Abbas Moghimbeigi Heidar Tavilani Source Type: research

Polymorphisms of DNA repair genes XRCC1 and LIG4 and idiopathic male infertility
. (Source: Systems Biology in Reproductive Medicine)
Source: Systems Biology in Reproductive Medicine - October 9, 2017 Category: Sexual Medicine Authors: Hadi Ghasemi Iraj Khodadadi Amir Fattahi Abbas Moghimbeigi Heidar Tavilani Source Type: research

Effectiveness of antibiotic treatment in infertile patients with sterile leukocytospermia induced by tobacco use
. (Source: Systems Biology in Reproductive Medicine)
Source: Systems Biology in Reproductive Medicine - September 8, 2017 Category: Sexual Medicine Authors: Bogdan Pajovic Ljiljana Pajovic Marko Vukovic Source Type: research

Effectiveness of antibiotic treatment in infertile patients with sterile leukocytospermia induced by tobacco use.
Abstract Our study investigated whether antibiotic therapy in infertile tobacco users with sterile leukocytospermia and a history of former sexual transmitted disease (STD) has an advantage over cessation of smoking alone. For this study, 80 male infertile smokers were divided into two subgroups. The first group numbered 40 patients treated with a two week course of doxycycline, 100 mg, twice daily, while the second group simply ceased smoking. A control group of 20 patients with chronic abacterial prostatitis (CPPS III a) were treated with the same antibiotic for two weeks. Patients from the first group exhibited...
Source: Systems Biology in Reproductive Medicine - September 8, 2017 Category: Reproduction Medicine Authors: Pajovic B, Pajovic L, Vukovic M Tags: Syst Biol Reprod Med Source Type: research

Effectiveness of antibiotic treatment in infertile patients with sterile leukocytospermia induced by tobacco use
. (Source: Systems Biology in Reproductive Medicine)
Source: Systems Biology in Reproductive Medicine - September 8, 2017 Category: Sexual Medicine Authors: Bogdan Pajovic Ljiljana Pajovic Marko Vukovic Source Type: research

In vitro effects of melatonin on colonization of neonate mouse spermatogonial stem cells
. (Source: Systems Biology in Reproductive Medicine)
Source: Systems Biology in Reproductive Medicine - August 28, 2017 Category: Sexual Medicine Authors: Shadan Navid Tayebeh Rastegar Maryam Baazm Rafieh Alizadeh Ali Talebi Keykavos Gholami Somayeh Khosravi-Farsani Morteza Koruji Mehdi Abbasi Source Type: research

In vitro effects of melatonin on colonization of neonate mouse spermatogonial stem cells.
Abstract We have recently reported that antioxidant supplements enhance the efficacy of cryopreserved spermatogonial stem cells. Melatonin is considered a free radical scavenger which has direct and indirect antioxidant effects in in vitro and in vivo microenvironments. Due to the anti-apoptotic properties of melatonin, researchers have proposed that melatonin may improve the efficiency of spermatogonial stem cell (SSC) transplantation. However, the appropriate methodology which facilitates SSC proliferation remains to be determined. Identification of a proper propagation system is essential for the future applica...
Source: Systems Biology in Reproductive Medicine - August 28, 2017 Category: Reproduction Medicine Authors: Navid S, Rastegar T, Baazm M, Alizadeh R, Talebi A, Gholami K, Khosravi-Farsani S, Koruji M, Abbasi M Tags: Syst Biol Reprod Med Source Type: research

In vitro effects of melatonin on colonization of neonate mouse spermatogonial stem cells
. (Source: Systems Biology in Reproductive Medicine)
Source: Systems Biology in Reproductive Medicine - August 28, 2017 Category: Sexual Medicine Authors: Shadan Navid Tayebeh Rastegar Maryam Baazm Rafieh Alizadeh Ali Talebi Keykavos Gholami Somayeh Khosravi-Farsani Morteza Koruji Mehdi Abbasi Source Type: research

The influence of semen quality on male pronucleus demethylation process during ICSI cycle
. (Source: Systems Biology in Reproductive Medicine)
Source: Systems Biology in Reproductive Medicine - August 25, 2017 Category: Sexual Medicine Authors: Hoda Rajabi Homa Mohseni-Kouchesfehani Mohammad Salehi Fattaneh Farifteh-Nobijari Tarlan Eslami-Arshaghi Source Type: research

The influence of semen quality on male pronucleus demethylation process during ICSI cycle.
Abstract There is growing evidence that the spermatozoon's epigenetic structure is of the utmost importance in the health of the future embryo. Following fertilization, sperm chromatin undergoes epigenetic reprogramming including DNA demethylation and remethylation, which resets gene expression. In some infertile patients, it is inevitable that sperm cells that are not within the range of normal human sperm parameters will be used for intracytoplasmic sperm injection. Understanding the relationship between the human sperm parameters and male pronucleus DNA demethylation seems necessary. We hypothesized that demeth...
Source: Systems Biology in Reproductive Medicine - August 25, 2017 Category: Reproduction Medicine Authors: Rajabi H, Mohseni-Kouchesfehani H, Salehi M, Farifteh-Nobijari F, Eslami-Arshaghi T Tags: Syst Biol Reprod Med Source Type: research

The influence of semen quality on male pronucleus demethylation process during ICSI cycle
. (Source: Systems Biology in Reproductive Medicine)
Source: Systems Biology in Reproductive Medicine - August 25, 2017 Category: Sexual Medicine Authors: Hoda Rajabi Homa Mohseni-Kouchesfehani Mohammad Salehi Fattaneh Farifteh-Nobijari Tarlan Eslami-Arshaghi Source Type: research

Analysis of embryo intactness and developmental potential following slow freezing and vitrification
Volume 63, Issue 5, October 2017, Page 285-293 . (Source: Systems Biology in Reproductive Medicine)
Source: Systems Biology in Reproductive Medicine - August 10, 2017 Category: Sexual Medicine Authors: Lan Yu Chanwei Jia Yonglian Lan Rui Song Liying Zhou Ying Li Yu Liang Shuyu Wang Source Type: research

Analysis of embryo intactness and developmental potential following slow freezing and vitrification.
Abstract The aim of this study was to identify the parameters that are related to intactness and developmental potential of a day 3 embryo after warming to improve the selection criteria used to cryopreserve and transfer embryos. We also sought to compare slow freezing and vitrification methods of cryopreservation and to evaluate the viability of non-intact embryos. Embryos warmed following slow freezing (n=220) or vitrification (n=522) were divided into 3 groups according to the proportion of surviving blastomeres (I
Source: Systems Biology in Reproductive Medicine - August 10, 2017 Category: Reproduction Medicine Authors: Yu L, Jia C, Lan Y, Song R, Zhou L, Li Y, Liang Y, Wang S Tags: Syst Biol Reprod Med Source Type: research

Analysis of embryo intactness and developmental potential following slow freezing and vitrification
. (Source: Systems Biology in Reproductive Medicine)
Source: Systems Biology in Reproductive Medicine - August 10, 2017 Category: Sexual Medicine Authors: Lan Yu Chanwei Jia Yonglian Lan Rui Song Liying Zhou Ying Li Yu Liang Shuyu Wang Source Type: research

Sperm Na+, K+-ATPase α4 and plasma membrane Ca2+-ATPase (PMCA) 4 regulation in asthenozoospermia
Volume 63, Issue 5, October 2017, Page 294-302 . (Source: Systems Biology in Reproductive Medicine)
Source: Systems Biology in Reproductive Medicine - August 8, 2017 Category: Sexual Medicine Authors: Silvia W. Lestari Dessy Noor Miati P. Seoharso R. Sugiyanto Dwi A. Pujianto Source Type: research

Sperm Na+, K+-ATPase α4 and plasma membrane Ca2+-ATPase (PMCA) 4 regulation in asthenozoospermia
. (Source: Systems Biology in Reproductive Medicine)
Source: Systems Biology in Reproductive Medicine - August 8, 2017 Category: Sexual Medicine Authors: Silvia W. Lestari Dessy Noor Miati P. Seoharso R. Sugiyanto Dwi A. Pujianto Source Type: research

Sperm Na(+), K(+)-ATPase α4 and plasma membrane Ca(2+)-ATPase (PMCA) 4 regulation in asthenozoospermia.
This study investigated the activities of Na(+), K(+)-ATPase and Ca(2+)-ATPase and the expression of Na(+), K(+)-ATPase α4 and PMCA4 isoforms in human sperm of asthenozoospermic infertile men. Nineteen samples from asthenozoospermic infertile couples were examined in this study. Computerized-assisted semen analysis (CASA) was performed, and the enzyme activity was measured based on the ability of ATPase to release organic phosphate from ATP as a substrate. The Na(+), K(+)-ATPase α4 and PMCA4 isoform expression levels were measured by western immunoblotting, whereas the protein distribution was examined by immun...
Source: Systems Biology in Reproductive Medicine - August 8, 2017 Category: Reproduction Medicine Authors: Lestari SW, Miati DN, Seoharso P, Sugiyanto R, Pujianto DA Tags: Syst Biol Reprod Med Source Type: research

Expression patterns and changes of the LCN2 gene in the testes of induced cryptorchidism and busulfan-treated mice
. (Source: Systems Biology in Reproductive Medicine)
Source: Systems Biology in Reproductive Medicine - August 3, 2017 Category: Sexual Medicine Authors: Zhenlong Kang Na Qiao Zhigang Tan Zhaoxin Tang Ying Li Source Type: research

Obstructive azoospermia caused by low ligation of varicocele: A case report
. (Source: Systems Biology in Reproductive Medicine)
Source: Systems Biology in Reproductive Medicine - August 3, 2017 Category: Sexual Medicine Authors: Jun Hagiuda Hiromichi Ishikawa Masayuki Hagiwara Hidaka Kono Ken Nakagawa Mototsugu Oya Source Type: research

Expression patterns and changes of the LCN2 gene in the testes of induced cryptorchidism and busulfan-treated mice
. (Source: Systems Biology in Reproductive Medicine)
Source: Systems Biology in Reproductive Medicine - August 3, 2017 Category: Sexual Medicine Authors: Zhenlong Kang Na Qiao Zhigang Tan Zhaoxin Tang Ying Li Source Type: research

Obstructive azoospermia caused by low ligation of varicocele: A case report
. (Source: Systems Biology in Reproductive Medicine)
Source: Systems Biology in Reproductive Medicine - August 3, 2017 Category: Sexual Medicine Authors: Jun Hagiuda Hiromichi Ishikawa Masayuki Hagiwara Hidaka Kono Ken Nakagawa Mototsugu Oya Source Type: research

Competitive inhibition of amino acid transport in human preovulatory ovarian follicles
. (Source: Systems Biology in Reproductive Medicine)
Source: Systems Biology in Reproductive Medicine - July 11, 2017 Category: Sexual Medicine Authors: Maciej J óźwik Marcin J óźwik Anna Justyna Milewska Frederick C. Battaglia Micha ł Jóźwik Source Type: research

The effect of G-CSF on infertile women undergoing IVF treatment: A meta-analysis.
This study aimed to evaluate the effectiveness of G-CSF on infertile women undergoing IVF. PubMed and EMBASE databases were searched before August 2016. Comparing the transvaginal perfusion of G-CSF and placebo or no treatment, the available studies were considered. The pooled risk ratio (RR) with 95% confidence intervals (CIs) was used in the analysis and six studies were included. Transvaginal perfusion of G-CSF was significantly associated with a higher clinical pregnancy rate versus the placebo (RR=1.563, 95%CI: 1.122, 2.176), especially for the Asian population. Among patients with a thin endometrium or repeated IVF f...
Source: Systems Biology in Reproductive Medicine - June 22, 2017 Category: Reproduction Medicine Authors: Li J, Mo S, Chen Y Tags: Syst Biol Reprod Med Source Type: research

Shortening gametes co-incubation time improves live birth rate for couples with a history of fragmented embryos
. (Source: Systems Biology in Reproductive Medicine)
Source: Systems Biology in Reproductive Medicine - June 20, 2017 Category: Sexual Medicine Authors: Anne Le Bras Laetitia Hesters Vanessa Gallot Cathie Tallet Gerard Tachdjian Nelly Frydman Source Type: research

Shortening gametes co-incubation time improves live birth rate for couples with a history of fragmented embryos.
Abstract Short gamete co-incubation (SGCO) consists in decreasing the duration of contact between oocytes and sperm from the standard overnight insemination (SOI) toward 2 hours. However, the effectiveness of this technique to improve in vitro fertilization and embryo transfer (IVF-ET) outcomes remains controversial. Our study was designed to evaluate the efficiency of SGCO in a poor prognosis population with a history of fragmented embryos defined by the presence of at least 50% of the embryos with more than 25% of cytoplasmic fragments. From January 2010 to January 2014, 97 couples were included in a SGCO protoc...
Source: Systems Biology in Reproductive Medicine - June 20, 2017 Category: Reproduction Medicine Authors: Le Bras A, Hesters L, Gallot V, Tallet C, Tachdjian G, Frydman N Tags: Syst Biol Reprod Med Source Type: research

Shortening gametes co-incubation time improves live birth rate for couples with a history of fragmented embryos
. (Source: Systems Biology in Reproductive Medicine)
Source: Systems Biology in Reproductive Medicine - June 20, 2017 Category: Sexual Medicine Authors: Anne Le Bras Laetitia Hesters Vanessa Gallot Cathie Tallet Gerard Tachdjian Nelly Frydman Source Type: research

The Impact of laparoscopic surgery of peritoneal endometriosis and endometrioma on the outcome of ICSI cycles
. (Source: Systems Biology in Reproductive Medicine)
Source: Systems Biology in Reproductive Medicine - June 13, 2017 Category: Sexual Medicine Authors: Ismail Guler Ahmet Erdem Yuksel Oguz Funda Cevher Mehmet Firat Mutlu Nuray Bozkurt Mesut Oktem Mehmet Erdem Source Type: research

The Impact of laparoscopic surgery of peritoneal endometriosis and endometrioma on the outcome of ICSI cycles.
Abstract Our objective was to assess the role of laparoscopic removal of ovarian endometriomas and ablation of peritoneal endometriosis on the outcome of intracytoplasmic sperm injection (ICSI) - Embryo Transfer cycles by comparing with the results of patients with untreated endometriomas and tubal factor without underlying endometriosis confirmed by laparoscopy. For this purpose, between 2002 and 2015, outcomes of 257 ICSI cycles of 150 patients, including 91 cycles of 48 patients in minimal endometriosis, 57 cycles of 25 patients in endometrioma removal, 65 cycles of 53 patients in non-operated endometrioma, and...
Source: Systems Biology in Reproductive Medicine - June 13, 2017 Category: Reproduction Medicine Authors: Guler I, Erdem A, Oguz Y, Cevher F, Mutlu MF, Bozkurt N, Oktem M, Erdem M Tags: Syst Biol Reprod Med Source Type: research

The Impact of laparoscopic surgery of peritoneal endometriosis and endometrioma on the outcome of ICSI cycles
. (Source: Systems Biology in Reproductive Medicine)
Source: Systems Biology in Reproductive Medicine - June 13, 2017 Category: Sexual Medicine Authors: Ismail Guler Ahmet Erdem Yuksel Oguz Funda Cevher Mehmet Firat Mutlu Nuray Bozkurt Mesut Oktem Mehmet Erdem Source Type: research

RNA-based ovarian cancer research from ‘a gene to systems biomedicine’ perspective
. (Source: Systems Biology in Reproductive Medicine)
Source: Systems Biology in Reproductive Medicine - June 2, 2017 Category: Sexual Medicine Authors: Esra Gov Medi Kori Kazim Yalcin Arga Source Type: research

RNA-based ovarian cancer research from 'a gene to systems biomedicine' perspective.
Abstract Ovarian cancer remains the leading cause of death from a gynecologic malignancy, and treatment of this disease is harder than any other type of female reproductive cancer. Improvements in the diagnosis and development of novel and effective treatment strategies for complex pathophysiologies, such as ovarian cancer, require a better understanding of disease emergence and mechanisms of progression through systems medicine approaches. RNA-level analyses generate new information that can help in understanding the mechanisms behind disease pathogenesis, to identify new biomarkers and therapeutic targets and in...
Source: Systems Biology in Reproductive Medicine - June 2, 2017 Category: Reproduction Medicine Authors: Gov E, Kori M, Arga KY Tags: Syst Biol Reprod Med Source Type: research

Impact of hydrosalpinx fluid on early human embryos
. (Source: Systems Biology in Reproductive Medicine)
Source: Systems Biology in Reproductive Medicine - May 9, 2017 Category: Sexual Medicine Authors: Hongchu Bao Qinglan Qu Xin Huang Meimei Wang Xinrong Wang Cuifang Hao Source Type: research

Impact of hydrosalpinx fluid on early human embryos.
This study aimed to investigate the impact of hydrosalpinx fluid (HF) on early human embryonic development. A total of 33 patients who underwent laparoscopic surgery for hydrosalpinx were selected, and the HF specimens obtained from these patients were subjected to bacterial culture, Chlamydia antigen detection, biochemical analysis, and cytokine detection. Meanwhile, human embryos derived from three pronuclei (3PN) were cultured in various HF concentrations. There was no significant difference in the chemical components and physical characteristics between colorless and colored HF specimens, apart from the glucose concent...
Source: Systems Biology in Reproductive Medicine - May 9, 2017 Category: Reproduction Medicine Authors: Bao H, Qu Q, Huang X, Wang M, Wang X, Hao C Tags: Syst Biol Reprod Med Source Type: research

Impact of hydrosalpinx fluid on early human embryos
. (Source: Systems Biology in Reproductive Medicine)
Source: Systems Biology in Reproductive Medicine - May 9, 2017 Category: Sexual Medicine Authors: Hongchu Bao Qinglan Qu Xin Huang Meimei Wang Xinrong Wang Cuifang Hao Source Type: research

Microdeletions at DYS448 and DYS387S1 associate with increased risk of male infertility
. (Source: Systems Biology in Reproductive Medicine)
Source: Systems Biology in Reproductive Medicine - May 8, 2017 Category: Sexual Medicine Authors: Yanqing Li Qiurong Zhao Hai Liu Source Type: research

Microdeletions at DYS448 and DYS387S1 associate with increased risk of male infertility.
Abstract Male infertility affects many people of reproductive age. Diagnosis and therapies based on descriptive semen parameters have helped some of the infertility patients; however, further progress in reproductive therapy demands a better understanding of the molecular and genetic causes for male infertility. Although Y chromosome microdeletions have been a hot subject of genetic studies on male infertility, the relationship between male infertility and microdeletions at Y chromosome loci DYS448, DYS387, and DYS627 remains unclear. Here we analyzed the microdeletions at these three loci in 200 infertility male ...
Source: Systems Biology in Reproductive Medicine - May 8, 2017 Category: Reproduction Medicine Authors: Li Y, Zhao Q, Liu H Tags: Syst Biol Reprod Med Source Type: research

Microdeletions at DYS448 and DYS387S1 associate with increased risk of male infertility
. (Source: Systems Biology in Reproductive Medicine)
Source: Systems Biology in Reproductive Medicine - May 8, 2017 Category: Sexual Medicine Authors: Yanqing Li Qiurong Zhao Hai Liu Source Type: research

Aberrantly expressed long noncoding RNAs in recurrent implantation failure:A microarray related study
. (Source: Systems Biology in Reproductive Medicine)
Source: Systems Biology in Reproductive Medicine - April 25, 2017 Category: Sexual Medicine Authors: Li-juan Fan Hong-jing Han Jing Guan Xiao-wei Zhang Qing-hua Cui Huan Shen Cheng Shi Source Type: research