Correspondence
No abstract available (Source: RETINA)
Source: RETINA - August 1, 2018 Category: Opthalmology Tags: Correspondence Source Type: research

Reply
No abstract available (Source: RETINA)
Source: RETINA - August 1, 2018 Category: Opthalmology Tags: Correspondence Source Type: research

Correspondence
No abstract available (Source: RETINA)
Source: RETINA - August 1, 2018 Category: Opthalmology Tags: Correspondence Source Type: research

Reply
No abstract available (Source: RETINA)
Source: RETINA - August 1, 2018 Category: Opthalmology Tags: Correspondence Source Type: research

Correspondence
No abstract available (Source: RETINA)
Source: RETINA - August 1, 2018 Category: Opthalmology Tags: Correspondence Source Type: research

Reply
No abstract available (Source: RETINA)
Source: RETINA - August 1, 2018 Category: Opthalmology Tags: Correspondence Source Type: research

Correspondence
No abstract available (Source: RETINA)
Source: RETINA - August 1, 2018 Category: Opthalmology Tags: Correspondence Source Type: research

Reply
No abstract available (Source: RETINA)
Source: RETINA - August 1, 2018 Category: Opthalmology Tags: Correspondence Source Type: research

Correspondence
No abstract available (Source: RETINA)
Source: RETINA - August 1, 2018 Category: Opthalmology Tags: Correspondence Source Type: research

Branch Retinal Artery Ischemia
No abstract available (Source: RETINA)
Source: RETINA - August 1, 2018 Category: Opthalmology Tags: Photo Essay Source Type: research

Diagnostic and Therapeutic Challenges
No abstract available (Source: RETINA)
Source: RETINA - August 1, 2018 Category: Opthalmology Tags: Diagnostic and Therapeutic Challenges Source Type: research

Changes in choroidal thickness in clinically significant pseudophakic cystoid macular edema
Purpose: To investigate choroidal thickness in eyes with clinically significant pseudophakic cystoid macular edema (PCME) during the acute phase and following resolution of the edema, using enhanced depth imaging spectral domain optical coherence tomography (EDI-OCT). Methods: This is a retrospective, observational clinical study. Patients' records were reviewed for cases of clinically significant PCME after uneventful phacoemulsification surgery. Choroidal thickness was measured at time of PCME diagnosis in both eyes and after CME resolution in the affected eye using enhanced depth imaging spectral domain optical coh...
Source: RETINA - August 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Interocular asymmetry in choroidal thickness and retinal sensitivity in high myopia
Purpose: To investigate the normal range of interocular asymmetry in choroidal thickness and retinal sensitivity in high myopia without ocular fundus manifestations and to determine the relationship between interocular asymmetry and refractive error. Methods: Forty-three patients (35.07 ± 13.31 years) with high myopia and 45 healthy participants (39.9 ± 14.1 years) were administered an ocular coherence tomography and a microperimetry examination to determine choroidal thickness and retinal sensitivity at the foveal region and at 1, 2, and 3 mm, nasally, temporally, superiorly, and inferiorly. Absolute in...
Source: RETINA - August 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

The relationship between foveal avascular zone area, vessel density, and cystoid changes in diabetic retinopathy: an optical coherence tomography angiography study
Conclusion: The FAZ area and vessel density at the superficial capillary plexus level are reproducible and independent of the presence of cystoid edema. (Source: RETINA)
Source: RETINA - August 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Atypical form of retinopathy of prematurity with severe fibrovascular proliferation in the optic disk region
Conclusion: An atypical and severe form of ROP, in which fibrovascular proliferation grew mainly from the optic disk region, needs further investigation for treatment in addition to laser photocoagulation and vitreous surgery. (Source: RETINA)
Source: RETINA - August 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Short-term outcomes after intravitreal injections of conbercept versus ranibizumab for the treatment of retinopathy of prematurity
Conclusion: Both conbercept and ranibizumab are effective choice for the treatment of ROP. Conbercept is a novel effective treatment strategy for ROP providing a new treatment option for ophthalmologists. (Source: RETINA)
Source: RETINA - August 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Handheld spectral domain optical coherence tomography imaging through the undilated pupil in infants born preterm or with hypoxic injury or hydrocephalus
Conclusion: Undilated, handheld SDOCT imaging is a potential alternative method to evaluate the retina and optic nerve in patients with relative contraindication to pharmacological pupil dilation. This approach will enable the study of the eye–brain connection and ocular manifestations of neurologic diseases. (Source: RETINA)
Source: RETINA - August 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Time course of changes in metamorphopsia following intravitreal ranibizumab injection for branch retinal vein occlusion
Purpose: To evaluate the effects of intravitreal ranibizumab injection (IVR) on metamorphopsia in patients with branch retinal vein occlusion (BRVO) and to assess the relationship between retinal microstructure and metamorphopsia. Methods: Subjects were 39 eyes of 39 patients with branch retinal vein occlusion. The severity of metamorphopsia was quantified using the M-CHARTS before and 1, 2, 3, 4, 5, and 6 months after treatment. Based on optical coherence tomography (OCT) images, we assessed central retinal thickness (CRT) and status of the external limiting membrane (ELM) and ellipsoid zone (EZ). The association bet...
Source: RETINA - August 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

EVALUATION OF MACULAR ISCHEMIA IN EYES WITH CENTRAL RETINAL VEIN OCCLUSION: An Optical Coherence Tomography Angiography Study
Conclusion: Optical coherence tomography angiography is a novel technique that enables segmented evaluation of the macular perfusion status in eyes with central retinal vein occlusion and provides visual prognostic information. Enlargement of the macular NPA in the superficial and deep layers was significantly correlated with impaired visual acuity and with decreased macular sensitivity in patients with aflibercept-treated central retinal vein occlusion and resolved macular edema. (Source: RETINA)
Source: RETINA - August 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY IN RETINAL VEIN OCCLUSION: Correlations Between Macular Vascular Density, Visual Acuity, and Peripheral Nonperfusion Area on Fluorescein Angiography
Purpose: To study correlations in patients with retinal vein occlusion between the automatically quantified macular vascular densities in the superficial and deep capillary plexus (DCP) obtained using optical coherence tomography angiography (OCTA) and the data from conventional examination, particularly visual acuity and peripheral retinal nonperfusion assessed using fluorescein angiography (FA). Methods: Retrospective, observational study of patients with retinal vein occlusion who underwent a comprehensive ophthalmic examination including FA and OCTA using the AngioVue OCTA system version 2015.100.0.35 (OptovueRTVu...
Source: RETINA - August 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Comparison of 2d and 3d video displays for teaching vitreoretinal surgery
Purpose: To compare medical students' learning uptake and understanding of vitreoretinal surgeries by watching either 2D or 3D video recordings. Methods: Three vitreoretinal procedures (tractional retinal detachment, exposed scleral buckle removal, and four-point scleral fixation of an intraocular lens [TSS]) were recorded simultaneously with a conventional recorder for two-dimensional viewing and a VERION 3D HD system using Sony HVO-1000MD for three-dimensional viewing. Two videos of each surgery, one 2D and the other 3D, were edited to have the same content side by side. One hundred UMass medical students randomly a...
Source: RETINA - August 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Residual vitreous cortex at the fovea during vitrectomy for primary rhegmatogenous retinal detachment repair
Conclusion: Eyes with residual cortex have a higher rate of ERM than eyes with no residual cortex after vitrectomy for primary repair. It is uncertain whether removing the cortex reduces the rate of postoperative ERM. The residual cortex may have already started the pathogenesis of ERM, or surgical trauma may have played a role. (Source: RETINA)
Source: RETINA - August 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

OCRIPLASMIN FOR VITREOMACULAR TRACTION: LOOKING OUTSIDE THE MACULAA Wide-Field Optical Coherence Tomography Study
Conclusion: Intravitreal ocriplasmin injection induced resolution of VMT in most cases and more rarely a release of vitreopapillary adhesion and a complete posterior vitreous detachment. An acute panretinopathy was visible in more than half of the patients and was not related to vitreous detachment. (Source: RETINA)
Source: RETINA - August 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Predictive factors of visual outcome for vitreomacular traction syndrome after vitrectomy
Purpose: To assess the long-term functional and anatomical outcomes for vitreomacular traction syndrome (VMT) after vitrectomy and to analyze the predictive factors regarding visual outcome. Methods: A retrospective, consecutive case series of 22 eyes in 22 patients with VMT who underwent vitrectomy to relieve macular edema were studied. Eyes were classified into two groups according to the diameter of vitreomacular adhesion based on spectral domain optical coherence tomography: Group 1 (14 eyes) focal attachment ≤1,500 μm; and Group 2 (eight eyes) broad attachment>1,500 μm. Results: Mean postoperative ...
Source: RETINA - August 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Anti-vascular endothelial growth factor therapy versus photodynamic therapy in the treatment of choroidal neovascularization secondary to central serous chorioretinopathy
Conclusion: PDT and IVT inhibitors alone or combined show similar clinical effects in chronic central serous chorioretinopathy eyes with choroidal neovascularization. (Source: RETINA)
Source: RETINA - August 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

OPTICAL COHERENCE TOMOGRAPHY ANALYSIS OF OUTER RETINAL TUBULATIONS: Sequential Evolution and Pathophysiological Insights
Purpose: To describe the sequential evolution of outer retinal tubulations (ORTs) in patients diagnosed with choroidal neovascularization and/or retinal pigment epithelium atrophy. Methods: Retrospective evaluation of spectral domain optical coherence tomography of a consecutive cohort of patients with various retinal conditions. Results: We reviewed the clinical findings of 238 eyes of 119 consecutive patients (54 men and 65 women) with a mean age of 76.2 ± 14.2 years (range: 57–90) and a mean follow-up of 3 ± 1.6 years (range 1–7). Over the follow-up period, ORTs were diagnosed in 67 of ...
Source: RETINA - August 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Choroidal vascular hyperpermeability as a predictor of treatment response for polypoidal choroidal vasculopathy
Conclusion: The presence of CVH is associated with better visual outcome in eyes with polypoidal choroidal vasculopathy and lower injection number in combination therapy. Thus, CVH, but not choroidal thickness, should be further evaluated as a potential biomarker for selecting patients for combination therapy. (Source: RETINA)
Source: RETINA - August 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

OUTCOMES OF PATIENTS WITH EXUDATIVE AGE-RELATED MACULAR DEGENERATION TREATED WITH ANTIVASCULAR ENDOTHELIAL GROWTH FACTOR THERAPY FOR THREE OR MORE YEARS: A Review of Current Outcomes
Conclusion: The body of evidence to date regarding long-term anti-VEGF treatment indicates a variable course at greater than 36 months follow-up and seems to be dependent on the treatment protocol. Consistent dosing with fluid-free interval is suggested to maintain VA gains in patients with exudative age-related macular degeneration. There is no evidence suggesting that there are additional adverse events from long-term anti-VEGF use. (Source: RETINA)
Source: RETINA - August 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Predictors of one-year visual outcomes after anti-vascular endothelial growth factor treatment for neovascular age-related macular degeneration
Purpose: To determine predictors of best-corrected visual acuity (BCVA) outcomes 1 year after ranibizumab or bevacizumab treatment for neovascular age-related macular degeneration, within the French Study Group Avastin versus Lucentis for neovascular age-related macular degeneration (GEFAL). Methods: Patients aged ≥50 years presenting subfoveal neovascular age-related macular degeneration were randomized to receive ranibizumab or bevacizumab (3 monthly intravitreal injections followed by an as-needed regimen). The main outcome measures were BCVA and its change from baseline at 1 year. Variables with a P value (Source: RETINA)
Source: RETINA - August 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Prognostic value of subretinal hyperreflective material in neovascular age-related macular degeneration treated with bevacizumab
Conclusion: This study supports the use of SHRM as a prognostic biomarker when interpreting optical coherence tomography in neovascular age-related macular degeneration. Baseline parameters predicting poorer vision 1 year after intravitreal bevacizumab treatment were as follows: presence of central SHRM, well-defined SHRM borders, intraretinal fluid, and thicker SHRM. (Source: RETINA)
Source: RETINA - August 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Quantitative analysis of the inner retinal layer thicknesses in age-related macular degeneration using corrected optical coherence tomography segmentation
Conclusion: In patients with dry AMD, automatic optical coherence tomography segmentation algorithms may be erroneous. As the severity of dry AMD increases, the inner plexiform layer layer becomes thinned, suggesting that transsynaptic degeneration may be occurring, as the photoreceptor layer is affected by AMD. (Source: RETINA)
Source: RETINA - August 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

EFFICACY AND SAFETY OF RANIBIZUMAB FOR THE TREATMENT OF CHOROIDAL NEOVASCULARIZATION DUE TO UNCOMMON CAUSE: Twelve-Month Results of the MINERVA Study
Purpose: To evaluate the efficacy and safety of ranibizumab 0.5 mg in adult patients with choroidal neovascularization because of an uncommon cause enrolled in the 12-month MINERVA study. Methods: In this Phase III, double-masked study, adult (≥18 years) patients (N = 178) were randomized 2:1 to receive either ranibizumab (n = 119) or sham (n = 59) at baseline and, if needed, at Month 1 and open-label individualized ranibizumab from Month 2. Best-corrected visual acuity change from baseline to Month 2 (primary endpoint) and Month 12, treatment exposure, and safety over 12 months were reported. Subgroup analysis was...
Source: RETINA - August 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Classification and quantitative analysis of geographic atrophy junctional zone using spectral domain optical coherence tomography
Purpose: The junctional zone at the border of areas of geographic atrophy (GA) in eyes with nonneovascular age-related macular degeneration is an important target region for future therapeutic strategies. The goal of this study was to perform a detailed classification and quantitative characterization of the junctional zone using spectral domain optical coherence tomography. Methods: Spectral domain optical coherence tomography volume cube scans (Spectralis OCT, 1024 × 37, Automatic Real Time> 9) were obtained from 15 eyes of 11 patients with GA because of nonneovascular age-related macular degeneration. Volu...
Source: RETINA - August 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Crispr genome surgery in the retina in light of off-targeting
Conclusion: The CRISPR system has high potential to be an invaluable therapeutic tool as it has the ability to modify and repair pathogenic retinal lesions. Although it is not yet a perfect system, with further efforts to improve its specificity and efficacy along with careful screening of off-target mutations, CRISPR-mediated genome surgery potential can become maximized and applied to patients. (Source: RETINA)
Source: RETINA - August 1, 2018 Category: Opthalmology Tags: Review Source Type: research

Multimodal Imaging in Purtscher Retinopathy
No abstract available (Source: RETINA)
Source: RETINA - June 22, 2018 Category: Opthalmology Tags: Photo Essay Source Type: research

Multimodal Imaging in a Case of Fundus Pulverulentus
No abstract available (Source: RETINA)
Source: RETINA - June 22, 2018 Category: Opthalmology Tags: Photo Essay Source Type: research

Leopard-Spot Subretinal Deposits in Central Serous Chorioretinopathy
No abstract available (Source: RETINA)
Source: RETINA - June 22, 2018 Category: Opthalmology Tags: Photo Essay Source Type: research

Multimodal Imaging of Optic Nerve Head Capillary Hemangioma
No abstract available (Source: RETINA)
Source: RETINA - June 22, 2018 Category: Opthalmology Tags: Photo Essay Source Type: research

Optical Coherence Tomography in Subconjunctival Silicone Oil
No abstract available (Source: RETINA)
Source: RETINA - June 22, 2018 Category: Opthalmology Tags: Photo Essay Source Type: research

Comet Lesions in Retinitis Pigmentosa
No abstract available (Source: RETINA)
Source: RETINA - June 22, 2018 Category: Opthalmology Tags: Photo Essay Source Type: research

Diagnostic and Therapeutic Challenges
No abstract available (Source: RETINA)
Source: RETINA - June 22, 2018 Category: Opthalmology Tags: Diagnostic and Therapeutic Challenges Source Type: research

Ex vivo model for the characterization and identification of drywall intraocular foreign bodies on computed tomography
Conclusion: Drywall dissolves in the eye and becomes denser over time as air in the drywall is replaced by fluid. This study identified Hounsfield Units specific to intraocular drywall foreign body over time. (Source: RETINA)
Source: RETINA - June 22, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Ellipsoid zone mapping and outer retinal assessment in stargardt disease
Purpose: To quantify and correlate ellipsoid zone and photoreceptor outer segment changes with visual acuity in Stargardt disease. Methods: An institutional review board–approved study of 32 eyes with Stargardt disease was performed. After spectral domain optical coherence tomography, the macular cube was exported into a novel analysis tool and volumetric assessment from the ellipsoid zone to the retinal pigment epithelium was performed. Using this information, mapping was completed with en face representation of the height between the ellipsoid zone and retinal pigment epithelium. This analysis provided quantif...
Source: RETINA - June 22, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Use of femoral artery ultrasound during intraarterial chemotherapy for children under 10 kg with retinoblastoma
Purpose: To demonstrate the safety and efficacy of intraarterial chemotherapy (IAC) in small infants ( (Source: RETINA)
Source: RETINA - June 22, 2018 Category: Opthalmology Tags: Original Study Source Type: research

FIVE-YEAR FOLLOW-UP AFTER EPIRETINAL MEMBRANE SURGERY: A Single-Center Experience
Conclusion: The recurrence rate of ERM after peeling surgery was reported as being around 5% to 12%. It was 58% in the current study. Because the recurrent ERM is generally mild, visual acuity was unaffected. (Source: RETINA)
Source: RETINA - June 22, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Risk factors for recurrences of central serous chorioretinopathy
Purpose: To describe recurrence patterns and investigate candidate risk factors for recurrences of central serous chorioretinopathy. Methods: In 46 patients with acute central serous chorioretinopathy and follow-up>12 months after first episode resolution, parameters influencing recurrences were retrospectively evaluated using a frailty Cox proportional hazard survival model. Covariates included baseline systemic findings: age, gender, corticosteroid use, stress, shift work, sleep disorder, depression, allergy, cardiovascular risk; baseline optical coherence tomography findings: subfoveal choroidal thickness, pigme...
Source: RETINA - June 22, 2018 Category: Opthalmology Tags: Original Study Source Type: research

RETINAL DETACHMENT SURGERY IN A PEDIATRIC POPULATION: Visual and Anatomic Outcomes
This study examined visual and anatomical outcomes of pediatric RD undergoing surgical repair at a single university referral center. Methods: A retrospective consecutive case series of patients clinically diagnosed and undergoing surgery for RD between birth and 15 years of age from 2002 to 2013 at a single academic institution. Results: A total of 206 patients (231 eyes) were included in this study, of which 25 (12%) had bilateral RD. Of those patients, 67 (29%) had TRD (retinopathy of prematurity, persistent fetal vasculature, or familial exudative vitreoretinopathy), 51 (22%) had rhegmatogenous retinal detachment...
Source: RETINA - June 22, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Role of early vitrectomy in the treatment of fungal endophthalmitis
Conclusion: A strong clinical suspicion that translates into early vitrectomy plus intravitreal antifungal antibiotics leads to favorable visual and structural outcomes. A long wait till microbiological confirmation to institute antifungal therapy may result in poorer outcome. (Source: RETINA)
Source: RETINA - June 22, 2018 Category: Opthalmology Tags: Original Study Source Type: research

COMBINED PARS PLANA VITRECTOMY AND SCLERAL FIXATION OF AN INTRAOCULAR LENS USING GORE-TEX SUTURE: One-Year Outcomes
Purpose: To report the 1-year clinical outcomes of combined pars plana vitrectomy and ab externo scleral fixation of an intraocular lens using Gore-Tex suture. Methods: Retrospective, interventional case series. Outcome measures were change in visual acuity and occurrence of intraoperative and postoperative complications with minimum follow-up of 1 year. Results: Eighty-four eyes of 83 patients were identified. The mean best available visual acuity improved from 20/782 preoperatively to 20/65 postoperatively (P (Source: RETINA)
Source: RETINA - June 22, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Ocular manifestations of systemic amyloidosis
Conclusion: Systemic amyloidosis can lead to ocular morbidity. Patients with AL amyloidosis had involvement of the temporal artery, conjunctiva, extraocular muscles, trabecular meshwork, and cranial nerves. Those with gelsolin nontransthyretin familial amyloidosis were susceptible to corneal dystrophy. Patients with AA amyloidosis did not manifest ophthalmic involvement. Finally, if ocular amyloidosis is detected, patients should be referred for systemic workup. (Source: RETINA)
Source: RETINA - June 22, 2018 Category: Opthalmology Tags: Original Study Source Type: research