CAVERNOUS HEMANGIOMA OF THE RETINA: A Comprehensive Review of the Literature (1934–2015)
Conclusion: It is important to screen family members in bilateral CHR cases, and it is critical to exclude cerebral vascular abnormalities in view of relative high incidence of intracranial involvement and high morbidity. (Source: RETINA)
Source: RETINA - March 24, 2017 Category: Opthalmology Tags: Review Source Type: research

Choroidal Neovascularization
No abstract available (Source: RETINA)
Source: RETINA - March 24, 2017 Category: Opthalmology Tags: Editorial Source Type: research

Reply
No abstract available (Source: RETINA)
Source: RETINA - February 23, 2017 Category: Opthalmology Tags: Correspondence Source Type: research

Correspondence
No abstract available (Source: RETINA)
Source: RETINA - February 23, 2017 Category: Opthalmology Tags: Correspondence Source Type: research

Reply
No abstract available (Source: RETINA)
Source: RETINA - February 23, 2017 Category: Opthalmology Tags: Correspondence Source Type: research

Correspondence
No abstract available (Source: RETINA)
Source: RETINA - February 23, 2017 Category: Opthalmology Tags: Correspondence Source Type: research

Reply
No abstract available (Source: RETINA)
Source: RETINA - February 23, 2017 Category: Opthalmology Tags: Correspondence Source Type: research

Correspondence
No abstract available (Source: RETINA)
Source: RETINA - February 23, 2017 Category: Opthalmology Tags: Correspondence Source Type: research

Reply
No abstract available (Source: RETINA)
Source: RETINA - February 23, 2017 Category: Opthalmology Tags: Correspondence Source Type: research

Correspondence
No abstract available (Source: RETINA)
Source: RETINA - February 23, 2017 Category: Opthalmology Tags: Correspondence Source Type: research

Retinal Hemangioblastoma and Syrinx in von Hippel–Lindau Disease
No abstract available (Source: RETINA)
Source: RETINA - February 23, 2017 Category: Opthalmology Tags: Photo Essay Source Type: research

Iris Atrophy: A Novel Sign of Repeated Self-inflicted Laser Pointer Maculopathy
No abstract available (Source: RETINA)
Source: RETINA - February 23, 2017 Category: Opthalmology Tags: Photo Essay Source Type: research

Simultaneous Clear Lens Extraction and Silicon Oil Removal in Vitrectomized Myopic Eyes
No abstract available (Source: RETINA)
Source: RETINA - February 23, 2017 Category: Opthalmology Tags: Surgical Technique Source Type: research

COMPUTER ASSISTED RETINAL VESSEL TORTUOSITY EVALUATION IN NOVEL MUTATION FABRY DISEASE: Towards New Prognostic Markers
Conclusion: p.M187R mutation causes a severe systemic and ophthalmologic phenotype, in both male and female patients. Semiautomatic assessment of retinal vessel tortuosity is an objective and reproducible tool. All three parameters of tortuosity are closely associated with Fabry severity scores. Studies of larger series are being awaited to establish the role of retinal vessel tortuosity as a noninvasive marker of disease progression. (Source: RETINA)
Source: RETINA - February 23, 2017 Category: Opthalmology Tags: Original Study Source Type: research

Clinical features of affected and undetached fellow eyes in patients with fevr-associated rhegmatogenous retinal detachment
Conclusion: Male patients with FEVR-RRD experience an earlier onset than females in our series. Retinal tears, even giant tears, could be responsible for FEVR-RRD. The fellow eyes of FEVR-RRD patients were characterized by predetachment changes, which need both lifelong monitoring and timely vision-saving intervention. (Source: RETINA)
Source: RETINA - February 23, 2017 Category: Opthalmology Tags: Original Study Source Type: research

Outer retinal tubulation in retinal dystrophies
Conclusion: ORTs are present in patients with RP, STGD and Best disease with a higher frequency in Best disease. (Source: RETINA)
Source: RETINA - February 23, 2017 Category: Opthalmology Tags: Original Study Source Type: research

The effect of photopigment bleaching on fundus autofluorescence in acute central serous chorioretinopathy
Purpose: To evaluate the effect of photobleaching on fundus autofluorescence (FAF) images in acute central serous chorioretinopathy. Methods: We obtained prephotobleaching and postphotobleaching images using an Optomap 200Tx, and photobleaching was induced with a Heidelberg Retina Angiograph 2. Degrees of photobleaching were assessed as grayscale values in Optomap images. Concordances among the three kinds of images were analyzed. Hyper-AF lesions in prephotobleaching images were classified as Type 1 (changed to normal-AF after photobleaching) and Type 2 (unchanged after photobleaching). The FAF composite patterns of cent...
Source: RETINA - February 23, 2017 Category: Opthalmology Tags: Original Study Source Type: research

TREAT-AND-EXTEND REGIMEN USING RANIBIZUMAB FOR POLYPOIDAL CHOROIDAL VASCULOPATHY: One-Year Results
Purpose: To investigate the efficacy of a treat-and-extend regimen (TER) using ranibizumab to treat polypoidal choroidal vasculopathy (PCV). Methods: We retrospectively reviewed the medical records of 29 patients with PCV, who had been treated with a TER for 1 year. The primary outcome was the proportion of eyes that did not lose ≥3 best-corrected visual acuity (BCVA) lines. The number of intravitreal injections and recurrences as well as the maximum treatment interval without recurrence were analyzed. Results: The mean BCVA improved from 0.64 ± 0.42 logMAR (median, 20/80) at baseline to 0.30 ± 0.31 logM...
Source: RETINA - February 23, 2017 Category: Opthalmology Tags: Original Study Source Type: research

Evaluation of short-term outcomes of intravitreal aflibercept injections for age-related macular degeneration using focal macular electroretinography
Purpose: To evaluate the relationship between morphological changes and functional improvements assessed using focal macular electroretinograms after intravitreal aflibercept (IVA) injections in eyes with wet age-related macular degeneration. Methods: The clinical records of 42 eyes of 42 consecutive patients with naive, wet age-related macular degeneration received 3 monthly IVA were reviewed. The best-corrected visual acuity, central foveal thickness, outer retinal thickness, inner retinal thickness at baseline and 1 month after each IVA, and focal macular electroretinograms at baseline and 1 month after the first and t...
Source: RETINA - February 23, 2017 Category: Opthalmology Tags: Original Study Source Type: research

DETRIMENTAL EFFECTS OF ACTIVE INTERNAL LIMITING MEMBRANE PEELING DURING EPIRETINAL MEMBRANE SURGERY: Microperimetric Analysis
Introduction: The aim of the study was to assess the microperimetric consequences of active internal limiting membrane (ILM) peeling during idiopathic epimacular membrane (IEMM) surgery. Materials and Methods: This retrospective monocentric study included 32 eyes of 31 consecutive patients who underwent IEMM surgery. Internal limiting membrane integrity was assessed by ILM Blue staining after IEMM removal: peeling was spontaneous (Group S) or active (Group A). Preprocedure and postprocedure (1 and 6 months) examinations were performed using visual acuity determination, spectral domain optical coherence tomography and micr...
Source: RETINA - February 23, 2017 Category: Opthalmology Tags: Original Study Source Type: research

Is there a role of acth in increased choroidal thickness in cushing syndrome?
Conclusion: Cushing syndrome is associated with increased CT. The ACTH-dependent CS may increase CT more than ACTH-independent CS. This effect may be directly related to ACTH itself or increased plasma cortisol levels or both. (Source: RETINA)
Source: RETINA - February 23, 2017 Category: Opthalmology Tags: Original Study Source Type: research

Choroidal thickness in multisystemic autoimmune diseases without ophthalmologic manifestations
Purpose: To evaluate choroidal morphology and thickness at the posterior pole of individuals affected by multisystemic autoimmune diseases and without known ophthalmologic manifestations. Methods: Retrospective cross-sectional study including 75 patients with autoimmune diseases (divided according to their specific disease) and 80 healthy controls. A spectral-domain optical coherence tomography using enhanced depth imaging was performed and choroidal thickness was measured in the center of fovea and at 500 μm intervals along a horizontal section. Results: Lupus patients presented a thicker subfoveal choroid than contr...
Source: RETINA - February 23, 2017 Category: Opthalmology Tags: Original Study Source Type: research

Characterization of macular choroidal thickness in ischemic and nonischemic diabetic maculopathy
Purpose: To evaluate changes in macular choroidal thickness in eyes with ischemic and nonischemic diabetic maculopathy. Methods: Cross-sectional study of enhanced depth imaging optical coherence tomography of patients with diabetes. The diabetic eyes were divided into 3 groups: 1) eyes with no diabetic retinopathy (NDR); 2) those with diabetic retinopathy without macular ischemia (DR/MI−); and 3) those with diabetic retinopathy and macular ischemia (DR/MI+). Results: This analysis included 261 eyes of 160 patients. Eighty-eight eyes belonged to the NDR, 90 to the DR/MI−, and 83 to the DR/MI+ group. The choroi...
Source: RETINA - February 23, 2017 Category: Opthalmology Tags: Original Study Source Type: research

Comparison of the lamina cribrosa thickness of patients with unilateral branch retinal vein occlusion and healthy subjects
Purpose: To compare the lamina cribrosa (LC) thickness of healthy subjects and patients with unilateral branch retinal vein occlusion (BRVO), and to determine possible correlations between the LC thickness and the BRVO subtypes. Methods: This prospective, cross-sectional study included a total of 46 patients with naive, untreated, unilateral BRVO and 31 healthy control subjects. The occlusion site was divided into two BRVO types: arteriovenous crossing BRVO (AV-BRVO) and optic nerve BRVO (ON-BRVO). The optic nerve head was scanned using enhanced-depth imaging with the Spectralis optical coherence tomography system. Resul...
Source: RETINA - February 23, 2017 Category: Opthalmology Tags: Original Study Source Type: research

EARLY CRT MONITORING USING TIME-DOMAIN OPTICAL COHERENCE TOMOGRAPHY DOES NOT ADD TO VISUAL ACUITY FOR PREDICTING VISUAL LOSS IN PATIENTS WITH CENTRAL RETINAL VEIN OCCLUSION TREATED WITH INTRAVITREAL RANIBIZUMAB: A Secondary Analysis of Trial Data
Purpose: Our primary purpose was to assess the clinical (predictive) validity of central retinal thickness (CRT) and best corrected visual acuity (BCVA) at 1 week and 1 month after starting treatment with ranibizumab for central retinal vein occlusion. The authors also assessed detectability of response to treatment. Methods: The authors used data from 325 participants in the CRUISE study, which included measurement of time-domain CRT and BCVA at baseline, 1 week, 1 month, and 6 months postrandomization. Analysis of covariance models were fitted to assess clinical validity, and distributions of change were constructed to ...
Source: RETINA - February 23, 2017 Category: Opthalmology Tags: Original Study Source Type: research

Association between retinal hemorrhagic patterns and perfusion status in eyes with acute central retinal vein occlusion
Purpose: To evaluate peripheral retinal hemorrhagic patterns in eyes with acute central retinal vein occlusion, and to explore their clinical relevance in differentiating for the retinal perfusion status, through a prospective, and cross-sectional study. Methods: Fifty eyes with acute central retinal vein occlusion were included. Retinal hemorrhagic patterns at the equator and retinal perfusion status were evaluated by ultra-wide field fundus photography and fluorescein angiography. Results: Retinal perfusion was categorized as nonischemic in 29 eyes, ischemic in 18 eyes, and undeterminable in 3 eyes. None of the examine...
Source: RETINA - February 23, 2017 Category: Opthalmology Tags: Original Study Source Type: research

SUTURELESS CLEAR CORNEAL ULTRASONIC FRAGMENTATION FOR RETAINED LENS FRAGMENTS: A Pilot Study
Conclusion: Clear corneal, sutureless ultrasonic fragmentation seems to be a novel, safe, and efficient method for the removal of hard posteriorly dislocated lens fragments, sparing the need for a 20-gauge scleral port. (Source: RETINA)
Source: RETINA - February 23, 2017 Category: Opthalmology Tags: Original Study Source Type: research

COMPLETE SUBRETINAL FLUID DRAINAGE IS NOT NECESSARY DURING VITRECTOMY SURGERY FOR MACULA-OFF RHEGMATOGENOUS RETINAL DETACHMENT WITH PERIPHERAL BREAKS: A Prospective, Nonrandomized Comparative Interventional Study
Conclusion: Partial subretinal fluid drainage procedure during vitrectomy for the repair of macula-off rhegmatogenous retinal detachments revealed comparable results with CSFD in terms of anatomical and visual outcomes. Complete subretinal fluid drainage during vitrectomy seems to be unnecessary for all RRD reattachment surgical procedures. (Source: RETINA)
Source: RETINA - February 23, 2017 Category: Opthalmology Tags: Original Study Source Type: research

Features of posterior staphylomas analyzed in wide-field fundus images in patients with unilateral and bilateral pathologic myopia
Conclusion: Posterior staphyloma was found in 55% of 1,060 eyes with bilateral or unilateral pathologic myopia. Wide macular was the most common type, although there were much more variations in the shape of staphylomas than that had been previously believed. (Source: RETINA)
Source: RETINA - February 23, 2017 Category: Opthalmology Tags: Original Study Source Type: research

Correlations between preoperative retinal pigment epithelial protrusions and postoperative outcomes in eyes with idiopathic macular holes
Background/Purpose: To determine the relationship between the alterations in the preoperative morphology of the retinal pigment epithelium (RPE) and the postoperative recovery after surgery to close an idiopathic macular hole (MH). Methods: Retrospective interventional case series. Fifty-nine eyes of 59 patients with an idiopathic MH were studied. Pars plana vitrectomy was performed with the removal of the internal limiting membrane. The best-corrected visual acuity was measured, and the retinal morphology, including the presence of small RPE protrusions at the bottom of MH, was determined by spectral domain optical coher...
Source: RETINA - February 23, 2017 Category: Opthalmology Tags: Original Study Source Type: research

Efficacy of the inverted internal limiting membrane flap technique with vitrectomy for retinal detachment associated with myopic macular holes
Conclusion: Compared with conventional ILM peeling, the inverted ILM flap technique was more effective for macular hole closure after vitrectomy for MHRD in myopic eye but showed no advantage in the postoperative visual outcome in this study. (Source: RETINA)
Source: RETINA - February 23, 2017 Category: Opthalmology Tags: Original Study Source Type: research

Choroidal blood flow visualization in high myopia using a projection artifact method in optical coherence tomography angiography
Purpose: To visualize choroidal blood flow in larger vessels in highly myopic eyes using a phenomenon of the projection artifact to in the sclera using optical coherence tomography angiography. Methods: The retrospective study included 92 eyes (54 patients) with greater than 8 diopters of myopia. All eyes were examined using optical coherence tomography angiography (RTVue XR Avanti; Optovue Inc, Fremont, CA). The blood flow in choroidal vessels was evaluated by attempting to directly segment the choroid and also by placing the segmentation layer behind the choroid, within the sclera. Subfoveal choroidal thickness was also...
Source: RETINA - February 23, 2017 Category: Opthalmology Tags: Original Study Source Type: research

Closing macular holes with “macular plug” without gas tamponade and postoperative posturing
Purpose: To investigate the surgical results of macular hole surgery without gas tamponade or postoperative posturing in patients with Stage 3 and Stage 4 macular holes with ≥500 μm mean base diameter. Design: Retrospective interventional case series. Participants: Twenty-six patients with Stage 3 and Stage 4 macular holes. Methods: Twenty-six eyes of 26 patients with Stage 3 and Stage 4 macular holes and a mean base diameter of 892.8 ± 349 μm underwent pars plana 23-gauge vitrectomy with broad internal limiting membrane peel (ILM peel), inverted ILM flap repositioning (ILMR), and use of autologous gluco...
Source: RETINA - February 23, 2017 Category: Opthalmology Tags: Original Study Source Type: research

Superficial foveal avascular zone determined by optical coherence tomography angiography before and after macular hole surgery
Purpose: To determine the size of the superficial foveal avascular zone (FAZ) by optical coherence tomography angiography before and after surgery for an idiopathic macular hole. Methods: A retrospective, observational case series, in which 16 eyes of 16 patients with an idiopathic macular hole were studied. Pars plana vitrectomy was performed with internal limiting membrane peeling. The foveal retinal vasculature was examined by optical coherence tomography angiography, and the area of the superficial FAZ was determined before, and at 1 and 3 months after the surgery. The area of the macular hole was also measured in the...
Source: RETINA - February 23, 2017 Category: Opthalmology Tags: Original Study Source Type: research

Clinical spectrum of macular-foveal capillaries evaluated with optical coherence tomography angiography
Conclusion: Cases of persistent MFC are heterogeneous in demographic characteristics, fundus appearance, and visual function. However, MFC, presenting either as complete absence of the foveal avascular zone or only partial foveal avascularity, may complicate different retinal abnormalities or represents a coincident finding. (Source: RETINA)
Source: RETINA - February 23, 2017 Category: Opthalmology Tags: Original Study Source Type: research

Volume-rendered angiographic and structural optical coherence tomography angiography of macular telangiectasia type 2
Conclusion: There are contractile features of the tissue in the temporal macula and the number, size, and temporal variations in the cavitations have not been in not mentioned in previous published descriptions of MacTel2. Vascular invasion of deeper layers occurred in the temporal macula through the outer nuclear layer. Volume-rendered angiographic and structural optical coherence tomography offers unprecedented ability to examine the vascular interrelationships their associations with cavitations in the macula. (Source: RETINA)
Source: RETINA - February 23, 2017 Category: Opthalmology Tags: Original Study Source Type: research

Clinical progress in inherited retinal degenerations: gene therapy clinical trials and advances in genetic sequencing
Conclusion: Comprehensive next-generation genetic sequencing of all retinal dystrophy genes is changing the paradigm for how retinal specialists perform genetic testing for inherited retinal degenerations. Not only are high diagnostic yields obtained, but mutations in genes with novel clinical phenotypes are also identified. In the era of retinal gene therapy clinical trials, identifying specific genetic defects will increasingly be of use to identify patients who may enroll in clinical studies and benefit from novel therapies. (Source: RETINA)
Source: RETINA - February 23, 2017 Category: Opthalmology Tags: Review Source Type: research

Reply
No abstract available (Source: RETINA)
Source: RETINA - January 27, 2017 Category: Opthalmology Tags: Correspondence Source Type: research

Correspondence
No abstract available (Source: RETINA)
Source: RETINA - January 27, 2017 Category: Opthalmology Tags: Correspondence Source Type: research

In Vivo Visualization of Large Choroidal Vessels Obliteration in Geographic Atrophy
No abstract available (Source: RETINA)
Source: RETINA - January 27, 2017 Category: Opthalmology Tags: Photo Essay Source Type: research

Torpedo Maculopathy Presenting With a Vitelliform Lesion
No abstract available (Source: RETINA)
Source: RETINA - January 27, 2017 Category: Opthalmology Tags: Photo Essay Source Type: research

Spectral Domain-Optical Coherence Tomography Findings in Unilateral Rubella Retinopathy
No abstract available (Source: RETINA)
Source: RETINA - January 27, 2017 Category: Opthalmology Tags: Photo Essay Source Type: research

Retinal Arterioarterial Anastomosis After Embolic Branch Retinal Artery Occlusion
No abstract available (Source: RETINA)
Source: RETINA - January 27, 2017 Category: Opthalmology Tags: Photo Essay Source Type: research

Spectral-Domain Optical Coherence Tomography Findings in Cavernous Hemangioma of the Optic Disk
No abstract available (Source: RETINA)
Source: RETINA - January 27, 2017 Category: Opthalmology Tags: Photo Essay Source Type: research

Leukemic Optic Nerve Infiltration Complicated by Retinal Artery and Vein Occlusions
No abstract available (Source: RETINA)
Source: RETINA - January 27, 2017 Category: Opthalmology Tags: Photo Essay Source Type: research

In Vivo Hemodynamic Changes of Vortex Vein Varix on Real-Time Video Angiography
No abstract available (Source: RETINA)
Source: RETINA - January 27, 2017 Category: Opthalmology Tags: Photo Essay Source Type: research

MYOMELANOCYTIC CHOROIDAL TUMOR: Cytopathologic Diagnosis
Conclusion: Myomelanocytic choroidal tumors can be diagnosed on fine-needle biopsy. (Source: RETINA)
Source: RETINA - January 27, 2017 Category: Opthalmology Tags: Clinicopathologic Correlation Source Type: research

SIMULATION TRAINING IN VITREORETINAL SURGERY: A Low-Cost, Medium-Fidelity Model
No abstract available (Source: RETINA)
Source: RETINA - January 27, 2017 Category: Opthalmology Tags: New Instruments Source Type: research

Diagnostic and Therapeutic Challenges
No abstract available (Source: RETINA)
Source: RETINA - January 27, 2017 Category: Opthalmology Tags: Diagnostic and Therapeutic Challenges Source Type: research

Intraoperative Optical Coherence Tomography Validates the Immediate Efficacy of External Diathermy in Sealing 25-Gauge Sclerotomy Wounds
No abstract available (Source: RETINA)
Source: RETINA - January 27, 2017 Category: Opthalmology Tags: Surgical Technique Source Type: research