Endogenous Bacterial Chorioretinal Abscess Presenting With Unusual Retinal Pigment Epithelial Excrescences and Large Subretinal Hemorrhage
No abstract available (Source: RETINA)
Source: RETINA - May 22, 2020 Category: Opthalmology Tags: Photo Essay Source Type: research

Optical Coherence Tomography Angiography and Fluorescein Angiography Findings in Aminoglycoside Toxicity
No abstract available (Source: RETINA)
Source: RETINA - May 22, 2020 Category: Opthalmology Tags: Photo Essay Source Type: research

Epinephrine in the Bottle: Intraoperative vascular changes seen with intravitreal epinephrine
No abstract available (Source: RETINA)
Source: RETINA - May 22, 2020 Category: Opthalmology Tags: Photo Essay Source Type: research

Avulsion of Optic Nerve and Peripapillary Retina
No abstract available (Source: RETINA)
Source: RETINA - May 22, 2020 Category: Opthalmology Tags: Photo Essay Source Type: research

Diagnostic and Therapeutic Challenges
No abstract available (Source: RETINA)
Source: RETINA - May 22, 2020 Category: Opthalmology Tags: Diagnostic and Therapeutic Challenges Source Type: research

Blood chromium-cobalt levels in patients after total knee arthroplasty and their effect on the retinal nerve fiber layer and macular ganglion cell complex
Purpose: To study blood cobalt (Co) and chromium (Cr) levels in patients who have undergone total knee arthroplasty and their effect on the retinal nerve fiber layer and macular ganglion cell complex. Methods: One hundred patients who had undergone total knee arthroplasty and 50 healthy individuals who had no implants were included in the study. The patients were separated into two groups based on how long ago the prosthesis had been implanted (Group 1: 1 to 5 years; Group 2: 5 to 10 years). After a complete ophthalmological examination, retinal nerve fiber layer and macular ganglion cell complex of the patients were ...
Source: RETINA - May 22, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Comparison of visual/anatomical outcomes and recurrence rate between oral spironolactone and photodynamic therapy for nonresolving central serous chorioretinopathy
Conclusion: Oral SPRL treatment for nonresolving central serous chorioretinopathy showed good long-term visual/anatomical outcomes, compared with half-dose photodynamic therapy. However, recurrence was more likely to occur when using oral SPRL. (Source: RETINA)
Source: RETINA - May 22, 2020 Category: Opthalmology Tags: Original Study Source Type: research

TAMOXIFEN-INDUCED CHORIORETINAL CHANGES: An Optical Coherence Tomography and Optical Coherence Tomography Angiography Study
Conclusion: Subclinical structural retinal changes could indicate early retinal pigment epithelial and photoreceptor damage. The new finding of choroidal thinning could point toward another important pathophysiologic process in tamoxifen-induced toxicity. (Source: RETINA)
Source: RETINA - May 22, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Early vitamin a supplementation improves the outcome of retinopathy of prematurity in extremely preterm infants
This study assessed the efficacy and safety of early vitamin A (VA) supplementation to improve outcomes of retinopathy of prematurity in extremely preterm infants. Methods: A total of 262 eligible extremely preterm infants underwent randomization; of these, 132 were assigned to the VA group and 130 to the control group. The infants were administered a solution of VA (1,500 IU/day), added to their enteral feeds as soon as minimal feeding was introduced and continued for 28 days or until discharge. Results: With no adverse effects occurring, serum VA of the VA-supplemented infants on Days 14, 28, and postmenstrual 36 w...
Source: RETINA - May 22, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Strict posturing with or without bilateral patching for posterior vitreous detachment–related vitreous hemorrhage
Conclusion: In patients with suspected PVD-related VH, overnight bilateral patching was not superior to posturing alone in superior retina visualization, but in a post-hoc analysis of patients with confirmed PVD-related VH, bilateral patching was superior. (Source: RETINA)
Source: RETINA - May 22, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Correlation between macular microstructures and aniseikonia after idiopathic epiretinal membrane removal
Purpose: To analyze the correlation between preoperative measurements of macular microstructures and aniseikonia after epiretinal membrane removal. Methods: This retrospective study included 32 eyes of 32 patients who underwent epiretinal membrane surgery and were followed up for 12 months. Spectral-domain optical coherence tomography was used to measure the thicknesses of the ganglion cell layer–inner plexiform layer, inner nuclear layer (INL), and outer retinal layer in macular microstructures. The new aniseikonia test was used to measure vertical and horizontal aniseikonia scores. Results: There was a sign...
Source: RETINA - May 22, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Persistent loculated subretinal fluid after rhegmatogenous retinal detachment surgery
Purpose: To identify factors associated with persistent subretinal fluid (SRF) after small-gauge pars plana vitrectomy for primary rhegmatogenous retinal detachment. Methods: This retrospective study included patients from 2 tertiary centers who underwent pars plana vitrectomy for repair of rhegmatogenous retinal detachment between 2013 and 2016. Preoperative and intraoperative parameters were examined for association with development of SRF. Results: Overall, 153 eyes of 153 patients, mean age of 55.2 ± 17.9 years were included. Persistent SRF occurred in 15.0% (n = 23) and was associated with high myopia (...
Source: RETINA - May 22, 2020 Category: Opthalmology Tags: Original Study Source Type: research

One-year outcomes of a novel surgical technique for sutureless intrascleral fixation of a three-piece intraocular lens using a 30-gauge needle
Conclusion: The novel surgical technique for sutureless intrascleral fixation of a 3-piece intraocular lens is well tolerated 1 year after surgery. (Source: RETINA)
Source: RETINA - May 22, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Macular capillary dropout in familial exudative vitreoretinopathy and its relationship with visual acuity and disease progression
Purpose: To quantitatively detect the macular microvascular alterations of eyes with familial exudative vitreoretinopathy (FEVR) and analyze their associations with the severity and visual acuity of FEVR. Methods: A case–control study comprising 62 patients (62 eyes) with FEVR and 21 age-matched healthy individuals (21 eyes) with normal vision was conducted. Parafoveal vascular density (VD) was measured using optical coherence tomography angiography. Visual acuity, intraocular pressure, and axial length were recorded. Results: Parafoveal VD of eyes with FEVR was lower than that of the controls (P (Source: RETINA)
Source: RETINA - May 22, 2020 Category: Opthalmology Tags: Original Study Source Type: research

MACULAR TELANGIECTASIA TYPE 2: Acircularity Index and Quantitative Assessment of Foveal Avascular Zone Using Optical Coherence Tomography Angiography
Purpose: The purpose of this study was to investigate the foveal avascular zone area and its perimeter, the acircularity index of the foveal avascular zone, the vessel density surrounding the foveal avascular zone, and the vessel density in the foveal, parafoveal, and perifoveal areas and their associations with best-corrected visual acuity, central foveal average thickness, and volume of ellipsoid zone–retinal pigment epithelium in patients with macular telangiectasia Type 2 (MacTel 2). Methods: We retrospectively reviewed medical records of 22 eyes of 22 patients with MacTel 2 and 24 eyes of 24 healthy control...
Source: RETINA - May 22, 2020 Category: Opthalmology Tags: Original Study Source Type: research

CHARACTERISTICS OF TYPE 3 NEOVASCULARIZATION LESIONS: Focus on the Incidence of Multifocal Lesions and the Distribution of Lesion Location
Conclusion: Two or more multifocal lesions were noted in 12.2% of eyes with Type 3 neovascularization, and pseudodrusen incidence was higher in eyes with multifocal lesions. In addition, lesion distribution exhibited a fovea-sparing pattern. These characteristics may be associated with the distinct pathophysiology of Type 3 neovascularization. (Source: RETINA)
Source: RETINA - May 22, 2020 Category: Opthalmology Tags: Original Study Source Type: research

ACUTE RETINAL ISCHEMIA IN CENTRAL VERSUS BRANCH RETINAL ARTERY OCCLUSION: Changes in Retinal Layers' Thickness on Spectral-Domain Optical Coherence Tomography in Different Grades of Retinal Ischemia
Purpose: To compare changes in thickness of separate retinal layers between acute central and branch retinal artery occlusion (RAO) regarding the severity grade of retinal ischemia using spectral-domain optical coherence tomography. Methods: Design: retrospective, observational case–control series. Setting: institutional. Patients: 114 patients with acute RAO. Examinations were conducted with spectral-domain optical coherence tomography at the first visit (baseline). Observations: RAO was categorized as branch (43 patients) or central RAO (71 patients) clinically. Retinal artery occlusion was categorized into th...
Source: RETINA - May 22, 2020 Category: Opthalmology Tags: Original Study Source Type: research

PERIPHERAL ISCHEMIC RETINAL PHOTOCOAGULATION IN ADDITION TO INTRAVITREAL BEVACIZUMAB VERSUS INTRAVITREAL BEVACIZUMAB ALONE FOR THE TREATMENT OF MACULAR EDEMA SECONDARY TO CENTRAL RETINAL VEIN OCCLUSION: A Randomized Double-Masked Controlled Clinical Trial
Purpose: To investigate the effects of peripheral ischemic retinal photocoagulation in addition to intravitreal bevacizumab (IVB) in the treatment of macular edema due to ischemic central retinal vein occlusion. Methods: Forty-eight eyes of 48 treatment-naive patients were randomly selected and divided into 2 groups. Group A comprised 24 eyes that were treated with three consecutive monthly injections of IVB, and Group B comprised 24 eyes that were treated with IVB plus photocoagulation of the peripheral nonperfused retina. Further IVB injections were administered as needed in both groups. Monthly follow-up was conduc...
Source: RETINA - May 22, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Impact of retinal ischemia on functional and anatomical outcomes after anti–vascular endothelial growth factor therapy in patients with retinal vein occlusion
Conclusion: Findings support the use of anti–vascular endothelial growth factors in ischemic and nonischemic forms of RVO. (Source: RETINA)
Source: RETINA - May 22, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Prophylactic laser treatment to decrease the incidence of retinal detachment in fellow eyes of idiopathic giant retinal tears
Conclusion: This study suggests that prophylactic 360° laser treatment in the fellow eye of patients with an idiopathic GRT decreased the incidence of retinal detachment, lowering the high risk of visual loss due to a macula-off retinal detachment. (Source: RETINA)
Source: RETINA - May 22, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Peeling of the internal limiting membrane with foveal sparing for treatment of degenerative lamellar macular hole
Purpose: To compare the functional and anatomical results of fovea-sparing internal limiting membrane peeling during vitrectomy with those of observation for degenerative lamellar macular hole with lamellar hole–associated epiretinal proliferation. Design: A prospective, randomized, comparative pilot study. Methods: Thirty-six eyes were randomized to undergo surgery with foveal internal limiting membrane sparing (Group S) or observation only (Group C). The main outcome measures were foveal retinal sensitivity, visual acuity, and central retinal thickness. Results: After 6 months, a significant difference w...
Source: RETINA - May 22, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Lamellar macular holes in the presence of age-related macular degeneration
Conclusion: The incidence of degenerative LMH increased in advanced forms of AMD, whereas the presence of tractional LMH subtype may be unrelated to AMD evolution. (Source: RETINA)
Source: RETINA - May 22, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Morphological and functional characteristics at the onset of exudative conversion in age-related macular degeneration
Conclusion: Characteristic choroidal neovascularization–associated morphological changes are preceding disease conversion, while vision loss at the onset of exudation is minimal. Individual lesion types are related to specific changes in optical coherence tomography morphology already before the time of conversion. Our findings may help to elucidate the pathophysiology of neovascular age-related macular degeneration and support the diagnosis of imminent disease conversion. (Source: RETINA)
Source: RETINA - May 22, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Photoreceptor damage in diabetic choroidopathy
This study cohort underwent an ophthalmologic examination, including optical coherence tomography and optical coherence tomography angiography. The main outcome measures were as follows: 1) “normalized” reflectivity of en face image segmented at the ellipsoid zone level, which was calculated to quantify the photoreceptor damage, and 2) CC perfusion density. Secondary outcome measures were as follows: 1) superficial retinal capillary plexus (SCP), intermediate retinal capillary plexus (ICP), and deep retinal capillary plexus (DCP) perfusion density (based on the area of vessels); 2) SCP, ICP, and DCP vessel leng...
Source: RETINA - May 22, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Rapid macular capillary loss in patients with uncontrolled type 1 diabetes
Purpose: To analyze the evolution of macular vessel density (VD) over 1 year, during early worsening of diabetic retinopathy, in patients with uncontrolled Type 1 diabetes (T1D). Methods: Retrospective study of 12 eyes of 9 patients with T1D with early worsening of diabetic retinopathy imaged with optical coherence tomography angiography. The following data were collected at the time of pan retinal photocoagulation initiation and after 6 and 12 months: vessel density within three retinal plexuses—superficial vascular plexus, intermediate capillary plexus, and deep capillary plexus; foveal avascular zone area, ac...
Source: RETINA - May 22, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Comparison of intravitreal dexamethasone implant and aflibercept in patients with treatment-naive diabetic macular edema with serous retinal detachment
Purpose: To compare the efficacy and safety of intravitreal dexamethasone (DEX) implant versus aflibercept in patients with treatment-naive diabetic macular edema with inflammatory biomarkers. Methods: Ninety-eight eyes of 62 treatment-naive patients with diabetic macular edema with serous retinal detachment and hyperreflective foci were enrolled. Each patient was randomized to receive either aflibercept or DEX implant treatment. The treatment protocol included 3 monthly injections of 2 mg of aflibercept as a loading phase in the anti–vascular endothelial growth factor group and 0.7 mg of DEX implant in the DEX ...
Source: RETINA - May 22, 2020 Category: Opthalmology Tags: Original Study Source Type: research

The effect of age on aflibercept (eylea) response in diabetic macular edema
Purpose: To investigate the effect of age on aflibercept (Eylea) response in macular edema secondary to treatment-naive diabetic eyes. Methods: Two hundred seventy-three eyes of 273 treatment-naive patients with macular edema secondary to diabetes mellitus were enrolled in this study. The patients in the study were divided into the following 4 groups according to their ages: Group 1 (40–50 years), Group 2 (51–60 years), Group 3 (61–70 years), and Group 4 (>70 years). Three consecutive injections at intervals of 1 month were applied to all diabetic patients. The efficacy of the aflibercept treatmen...
Source: RETINA - May 22, 2020 Category: Opthalmology Tags: Original Study Source Type: research

SEVERITY OF DIABETIC MACULAR EDEMA CORRELATES WITH RETINAL VASCULAR BED AREA ON ULTRA-WIDE FIELD FLUORESCEIN ANGIOGRAPHY: DAVE Study
Purpose: To quantify retinal nonperfusion area and retinal vascular bed area (RVBA) in mm2 on ultra-widefield fluorescein angiography in eyes with diabetic macular edema (DME) and explore their relationship with the severity of DME. Methods: Prospective, observational case series. Baseline ultra-widefield fluorescein angiography images of 40 eyes from 29 patients with treatment-naive DME who participated in the DAVE study (NCT01552408) were stereographically projected at Doheny Image Reading Center. The retinal vasculature was automatically extracted to calculate RVBA. Nonperfusion area was manually delineated by two ...
Source: RETINA - May 22, 2020 Category: Opthalmology Tags: Original Study Source Type: research

ANTI–VASCULAR ENDOTHELIAL GROWTH FACTOR THERAPY AND RISK OF TRACTION RETINAL DETACHMENT IN EYES WITH PROLIFERATIVE DIABETIC RETINOPATHY: Pooled Analysis of Five DRCR Retina Network Randomized Clinical Trials
Conclusion: These findings do not support the hypothesis that anti-VEGF therapy for diabetic macular edema or PDR increases the risk of TRD among eyes with PDR similar to those enrolled in five DRCR Retina Network protocols for which prompt vitrectomy was not planned. (Source: RETINA)
Source: RETINA - May 22, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Suspending treatment of neovascular age-related macular degeneration in cases of futility
Conclusion: This publication introduces an algorithm to guide the management of neovascular age-related macular degeneration in patients showing poor response to anti-VEGF treatment and provides expert guidance for suspending anti-VEGF treatment in cases of futility. (Source: RETINA)
Source: RETINA - May 22, 2020 Category: Opthalmology Tags: Review Source Type: research

Futility as the Basis for Suspending Treatment of Neovascular Age-Related Macular Degeneration: An Important but not Easily Defined Concept
No abstract available (Source: RETINA)
Source: RETINA - May 22, 2020 Category: Opthalmology Tags: Editorial Source Type: research

TEMPORARY KERATOPROSTHESIS FOR PANORAMIC VIEWING SYSTEMS: A New Design
No abstract available (Source: RETINA)
Source: RETINA - April 21, 2020 Category: Opthalmology Tags: New Instruments Source Type: research

Silicone oil tamponade effect on macular layer thickness and visual acuity
Purpose: To evaluate the influence of silicone oil (SO) tamponade on retinal layers thickness and visual acuity in patients who underwent pars plana vitrectomy for rhegmatogenous retinal detachment. Methods: This is a retrospective case series of consecutive patients who underwent pars plana vitrectomy for rhegmatogenous retinal detachment with SO tamponade. Visual acuity and central macular thickness were measured with SO and at least a month after SO removal (SOR). Patients with insufficient or poor-quality images or macular pathologies such as macular edema or epiretinal membranes were excluded. Results: Forty-o...
Source: RETINA - April 21, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Adverse effect of macular intraretinal hemorrhage on the prognosis of submacular hemorrhage due to retinal arterial macroaneurysm rupture
This study included 23 eyes of 23 consecutive patients diagnosed with submacular hemorrhage associated with ruptured retinal arterial macroaneurysm. Cases underwent displacement of submacular hemorrhage (vitrectomy + subretinal injection of tissue plasminogen activator + air tamponade) and were followed up for 6 months after surgery. Localization of the preoperative hemorrhage and its effect on preoperative and postoperative best-corrected visual acuity, central retinal thickness, and continuity of the ellipsoid zone were measured. Results: Macular intraretinal hemorrhage (IRH) was observed in 17 eyes (73.9%, IRH [+] gr...
Source: RETINA - April 21, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Evaluation of photoreceptors, retinal capillary plexuses, and choriocapillaris in patients with birdshot chorioretinopathy
Purpose: To assess the status of the cone photoreceptors using adaptive optics flood illumination ophthalmoscopy in patients with birdshot chorioretinopathy and to study their relationship with optical coherence tomography (OCT) angiography. Methods: Seventeen patients with birdshot chorioretinopathy were studied using standard automated perimetry, color vision testing, fluorescein angiography, indocyanine green angiography, spectral domain OCT, enhanced depth imaging OCT, and adaptive optics flood illumination ophthalmoscopy (rtx1, Imagine Eyes, Orsay, France) in a 90 × 90-μm area at 1.5° temporal of the...
Source: RETINA - April 21, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Australian and new zealand study of photodynamic therapy in choroidal amelanotic melanoma
Conclusion: In this large series, primary PDT was highly effective in achieving initial regression of posterior choroidal amelanotic melanomas. Photodynamic therapy is a vision-preserving treatment option for these tumors; however, patients need to be followed up closely because there is a significant rate of recurrence. (Source: RETINA)
Source: RETINA - April 21, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Photodynamic therapy for extrafoveolar choroidal osteoma
Conclusion: Photodynamic therapy is an effective modality for the management of extrafoveolar choroidal osteoma, minimizing tumor growth toward the foveola and preserving visual acuity. (Source: RETINA)
Source: RETINA - April 21, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Choroidal vascularity index quantification in geographic atrophy using binarization of enhanced-depth imaging optical coherence tomographic scans
Purpose: To evaluate choroidal structural changes occurring over time in geographic atrophy (GA) secondary to age-related macular degeneration using choroidal vascularity index (CVI). Methods: Enhanced-depth imaging optical coherence tomography scans of 34 patients with GA and 32 control subjects were retrospectively analyzed. Data were collected at baseline and after a mean follow-up of 18.3 ± 8.3 months. Choroidal images were binarized using the ImageJ software, and the luminal area and stromal area were segmented. Choroidal vascularity index was defined as the ratio of luminal area to total choroid area. Re...
Source: RETINA - April 21, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Clinical features of patchy chorioretinal atrophy in pathologic myopia
Conclusion: These morphological findings may provide a basis for exploring the biomechanical etiology of the PAs as part of the development of pathologic myopia. (Source: RETINA)
Source: RETINA - April 21, 2020 Category: Opthalmology Tags: Original Study Source Type: research

POSTERIORLY INSERTED VITREOUS BASE: Preoperative Characteristics, Intraoperative Findings, and Outcomes After Vitrectomy
Conclusion: Any eye undergoing vitrectomy may have posteriorly inserted vitreous base, but those with a high number of retinal breaks and lattice near the equator may be at highest risk. Redetachment and proliferative vitreoretinopathy still occur despite knowledge of the disorder and adjuvant treatments. (Source: RETINA)
Source: RETINA - April 21, 2020 Category: Opthalmology Tags: Original Study Source Type: research

EVALUATION OF THE EFFECT OF TOPICAL INTERFERON α2b AS A COMPLEMENTARY TREATMENT OF MACULAR EDEMA OF PATIENTS WITH DIABETIC RETINOPATHY: A Double-Blind Placebo-Controlled Randomized Clinical Trial Study
Conclusion: This study evaluated the short-term effects of topical IFNα2b 1 MU/mL. The drug was well tolerated and may have an effect on improvement of best-corrected visual acuity in patients with diabetic macular edema. It also had an intraocular pressure lowering effect on the studied eyes. However, further studies are needed to confirm this finding. (Source: RETINA)
Source: RETINA - April 21, 2020 Category: Opthalmology Tags: Original Study Source Type: research

PATIENTS PRESENTING EMERGENTLY WITH PROLIFERATIVE DIABETIC RETINOPATHY: Follow-up and Factors Associated With Compliance
Purpose: To determine the rate of follow-up after emergent encounters for proliferative diabetic retinopathy and to identify patient or visit characteristics associated with follow-up compliance. Methods: A retrospective cohort study of patients presenting to an ophthalmic emergency department with active proliferative diabetic retinopathy between May 2014 and December 2016 was conducted. Demographic data and encounter data were gathered for each emergency department visit. Compliance with follow-up was defined as a completed clinic visit as scheduled after the emergency encounter. Results: A total of 590 emergency...
Source: RETINA - April 21, 2020 Category: Opthalmology Tags: Original Study Source Type: research

PRAGMATISM OF RANDOMIZED CLINICAL TRIALS ON RANIBIZUMAB FOR THE TREATMENT OF DIABETIC MACULAR EDEMA: Impact on Clinical Outcomes
Conclusion: Randomized clinical trials evaluating ranibizumab for diabetic macular edema were more pragmatic than explanatory. “Ineligible” patients still benefited from ranibizumab therapy. (Source: RETINA)
Source: RETINA - April 21, 2020 Category: Opthalmology Tags: Original Study Source Type: research

ENDOGENOUS ENDOPHTHALMITIS IN WESTERN AUSTRALIA: A Sixteen-Year Retrospective Study
Conclusion: The population frequency of endogenous endophthalmitis has not changed over 16 years despite the changing profile of pathogen and risk factors. Similar to previous studies in Asian and Western countries, visual and anatomical prognosis depends on initial visual acuity and isolated pathogen. Gram-negative and filamentous fungi culture predicted a worse visual outcome. (Source: RETINA)
Source: RETINA - April 21, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Vitrectomy for endophthalmitis in eyes with osteokeratoprosthesis
Conclusion: Endophthalmitis in eyes with previous osteokeratoprosthesis is a very severe complication with a reserved prognosis. Pars plana vitrectomy associated with intravitreal antibiotics leads to maintaining or increasing visual acuity in a small proportion of patients who otherwise would end up blind. (Source: RETINA)
Source: RETINA - April 21, 2020 Category: Opthalmology Tags: Original Study Source Type: research

ENTEROCOCCUS ENDOPHTHALMITIS: Clinical Settings, Antimicrobial Susceptibility, and Management Outcomes
Conclusion: Enterococcus is not an uncommon organism in the setting of endophthalmitis after open globe injury. Resistance to vancomycin is rare. Multidrug resistance pattern is restricted to E. faecalis. Visual outcome is poor despite early and appropriate therapy due to inherent organism virulence. (Source: RETINA)
Source: RETINA - April 21, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Detection of clinically unsuspected retinal neovascularization with wide-field optical coherence tomography angiography
Conclusion: Wide-field OCTA can detect small NV not seen on clinical examination or color photographs and may improve the clinical evaluation of DR. (Source: RETINA)
Source: RETINA - April 21, 2020 Category: Opthalmology Tags: Original Study Source Type: research

OPTICAL COHERENCE TOMOGRAPHY LEAKAGE IN NEOVASCULAR AGE-RELATED MACULAR DEGENERATION: Identification of Choroidal Neovascularization Activity by Location and Quantification of Abnormal Fluid Under Anti–Vascular Endothelial Growth Factor Therapy
Purpose: To test optical coherence tomography leakage in the identification and quantification of choroidal neovascularization–related fluid, its change after anti–vascular endothelial growth factor therapy in neovascular age-related macular degeneration eyes and its relation to functional outcome. Methods: Prospective analysis of a cohort of neovascular age-related macular degeneration cases treated with 2.0-mg intravitreal aflibercept. Eyes included were analyzed before, 1-week, and 1-month after one injection. Best-corrected visual acuity was assessed using Early Treatment Diabetic Retinopathy Study met...
Source: RETINA - April 21, 2020 Category: Opthalmology Tags: Original Research Source Type: research

Comparison between several optical coherence tomography angiography devices and indocyanine green angiography of choroidal neovascularization
Conclusion: The choroidal neovascularization area is larger when imaged with standard indocyanine green angiography than with different OCTA devices with different algorithms, wavelengths, and scan patterns. The differences between several OCTA devices in the evaluation of quantitative parameters of CNV, such as CNV area, vessel density, and fractal dimension, suggest the necessity to standardize OCTA measurements for research and clinical practice. (Source: RETINA)
Source: RETINA - April 21, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Assessing the accuracy of a large observational registry of neovascular age-related macular degeneration
Purpose: To evaluate the accuracy of an observational database that tracks real-world treatment outcomes for neovascular age-related macular degeneration. Methods: We audited 245 randomly sampled eyes from 189 patients with 3,356 visits from 11 doctors in the Fight Retinal Blindness! database. Sex, birth year, previous treatments received, treatment, and visual acuity were validated against the clinical notes. Error rates, the proportion of missed visits (the number of visits present in the patient record but not entered into Fight Retinal Blindness!), the level of agreement using Cohen's kappa (κ) and intraclas...
Source: RETINA - April 21, 2020 Category: Opthalmology Tags: Original Study Source Type: research