Retina, The Journal of Retinal and Vitreous Diseases 2020 Scientific Reviewers
No abstract available (Source: RETINA)
Source: RETINA - January 1, 2021 Category: Opthalmology Tags: Reviewer List Source Type: research

Reply
No abstract available (Source: RETINA)
Source: RETINA - January 1, 2021 Category: Opthalmology Tags: Correspondence Source Type: research

Correspondence
No abstract available (Source: RETINA)
Source: RETINA - January 1, 2021 Category: Opthalmology Tags: Correspondence Source Type: research

Multimodal Imaging of Acute Siderotic Maculopathy
No abstract available (Source: RETINA)
Source: RETINA - January 1, 2021 Category: Opthalmology Tags: Photo Essay Source Type: research

Modified portable camera endoscope for posterior segment surgery
No abstract available (Source: RETINA)
Source: RETINA - January 1, 2021 Category: Opthalmology Tags: New Instruments Source Type: research

Diagnostic and Therapeutic Challenges
No abstract available (Source: RETINA)
Source: RETINA - January 1, 2021 Category: Opthalmology Tags: Diagnostic and Therapeutic Challenges Source Type: research

CLINICAL CHARACTERISTICS AND NATURAL HISTORY OF RHO-ASSOCIATED RETINITIS PIGMENTOSA: A Long-Term Follow-Up Study
Purpose: To investigate the natural history of RHO-associated retinitis pigmentosa (RP). Methods: A multicenter, medical chart review of 100 patients with autosomal dominant RHO-associated RP. Results: Based on visual fields, time-to-event analysis revealed median ages of 52 and 79 years to reach low vision (central visual field (Source: RETINA)
Source: RETINA - January 1, 2021 Category: Opthalmology Tags: Original Study Source Type: research

TOXICITY AND EFFICACY OF INTRAVITREAL MELPHALAN FOR RETINOBLASTOMA: 25: µ: g Versus 30: µ: g
Conclusion: Electroretinogram-measured toxicity in retinoblastoma eyes treated with intravitreal injections was not found to be different across 25-µg and 30-µg injections. There were no cases of extraocular extension or metastatic deaths in our patient population. (Source: RETINA)
Source: RETINA - January 1, 2021 Category: Opthalmology Tags: Original Study Source Type: research

Clinical features of flat irregular pigment epithelial detachment associated with choroidal neovascularization in chronic central serous chorioretinopathy
Purpose: To describe the multimodal imaging characteristics of flat irregular pigment epithelial detachment (FIPED) in patients with chronic central serous chorioretinopathy and determine the risk factors for vascularized FIPED and to explore the activity of vascularized FIPED before and after half-dose photodynamic therapy. Methods: Multimodal imaging data of 185 eyes of 155 consecutive patients with chronic central serous chorioretinopathy included spectral domain optical coherence tomography, fluorescein angiography, and indocyanine green angiography. Optical coherence tomography angiography was available for...
Source: RETINA - January 1, 2021 Category: Opthalmology Tags: Original Study Source Type: research

Optical coherence tomography angiography-guided photodynamic therapy for acute central serous chorioretinopathy
Conclusion: Optical coherence tomography angiography-guided PDT seemed to be noninferior to ICGA-guided PDT for resolution of SRF at 3 months in eyes with acute central serous chorioretinopathy. (Source: RETINA)
Source: RETINA - January 1, 2021 Category: Opthalmology Tags: Original Study Source Type: research

Revised classification of the optical coherence tomography outer retinal bands based on central serous chorioretinopathy analysis
Conclusion: Our patients' OCT findings support the current standard that Band 3 is an outer retinal structure and that Band 4 represents the retinal pigment epithelium/Bruch complex. Confusion exists regarding whether the interdigitation zone extends halfway up or for the full length of the outer segments, and the hyporeflective band between Bands 3 and 4 has yet to receive an appropriate term. We therefore propose a modification to the IN•OCT Consensus classification by renaming the trilaminar hyporeflective, hyperreflective, and hyporeflective bands between Bands 2 and 4 as the outer segment–interdigitatio...
Source: RETINA - January 1, 2021 Category: Opthalmology Tags: Original Study Source Type: research

Intraocular and interocular differences in parafoveal vascular density in diabetic patients without diabetic retinopathy
Conclusion: Intraocular and interocular VD difference may be an easy and sensitive way to detect subtle early microvascular changes in diabetic patients. (Source: RETINA)
Source: RETINA - January 1, 2021 Category: Opthalmology Tags: Original Study Source Type: research

Anatomical changes on sequential multimodal imaging in perifoveal exudative vascular anomalous complex
Conclusion: Perifoveal exudative vascular anomalous complex is an idiopathic perifoveal retinal vascular abnormality that is associated with intraretinal cystic spaces. These intraretinal cystic spaces associated with a PEVAC lesion, and even the PEVAC lesion itself, can have a spontaneous resolution over time. (Source: RETINA)
Source: RETINA - January 1, 2021 Category: Opthalmology Tags: Original Study Source Type: research

Reduced vascular density in the choroid after treatment with photodynamic therapy combined with aflibercept in patients with polypoidal choroidal vasculopathy
Conclusion: Photodynamic therapy may cause occlusion of the choriocapillaris and middle vessels in the choroid, as well as stenosis of the large vessels. (Source: RETINA)
Source: RETINA - January 1, 2021 Category: Opthalmology Tags: Original Study Source Type: research

Phase 2 study of the safety and efficacy of brimonidine drug delivery system (brimo dds) generation 1 in patients with geographic atrophy secondary to age-related macular degeneration
Conclusion: Brimo DDS demonstrated a favorable safety profile and reduced GA lesion area growth at Month 3. Lesion growth at Month 12 was reduced in patients with baseline GA lesion area ≥6 mm2. The results support Phase 3 development. (Source: RETINA)
Source: RETINA - January 1, 2021 Category: Opthalmology Tags: Original Study Source Type: research

Sub-retinal pigment epithelium multilaminar hyperreflectivity at the onset of type 3 macular neovascularization
Purpose: To report the prevalence and treatment outcomes of eyes with sub-retinal pigment epithelium (sub-RPE) multilaminar hyperreflectivity at the onset/clinical detection of Type 3 macular neovascularization (MNV) secondary to exudative age-related macular degeneration. Methods: Retrospective analysis of consecutive patients diagnosed with Type 3 MNV secondary to age-related macular degeneration was performed. Eyes presenting with sub-RPE multilaminar hyperreflectivity on structural optical coherence tomography at the onset of Type 3 MNV were included in this study. An age-, sex-, and stage-matched control gr...
Source: RETINA - January 1, 2021 Category: Opthalmology Tags: Original Study Source Type: research

Beta-peripapillary atrophy and geographic atrophy in the comparison of age-related macular degeneration treatments trials
Conclusion: The extent of sclera/choroidal blood vessel B-PPA was associated with the GA incidence and size but not with the growth rate in eyes treated for neovascular age-related macular degeneration. Beta-peripapillary atrophy and GA may share some common pathophysiologic pathways unrelated to the GA-associated risk alleles evaluated. (Source: RETINA)
Source: RETINA - January 1, 2021 Category: Opthalmology Tags: Original Study Source Type: research

FIVE-YEAR INCIDENCE AND VISUAL ACUITY OUTCOMES FOR INTRAVITREAL THERAPY IN BILATERAL NEOVASCULAR AGE-RELATED MACULAR DEGENERATION: Fight Retinal Blindness! Project
Purpose: To compare treatment intensity and mean visual acuity gains for first- and second-affected eyes with age-related macular degeneration nAMD over 5 years of treatment. The cumulative incidence of second-eye involvement was assessed. Method: We analyzed data from the Fight Retinal Blindness! project database, a prospectively designed registry of “real-world” outcomes from Australia, New Zealand, Switzerland, and Singapore. Patients with bilateral age-related macular degeneration with ≥5 years of follow-up on treatment were included. Results: Six thousand five hundred and forty-two eye...
Source: RETINA - January 1, 2021 Category: Opthalmology Tags: Original Study Source Type: research

The correlation between aqueous vascular endothelial growth factor level and clinical activity in neovascular age-related macular degeneration
Purpose: The aim of the current study was to investigate the correlation between the pretreatment aqueous level of vascular endothelial growth factor (VEGF) and clinical activity in neovascular age-related macular degeneration. Methods: Patients with neovascular age-related macular degeneration treated by intravitreal ranibizumab injections and followed for 12 months were included in the current study. The treatment regimen consisted of three consecutive monthly intravitreal ranibizumab injections (loading treatment) followed by a pro re nata (PRN) treatment regimen. The aqueous VEGF levels were measured by enzy...
Source: RETINA - January 1, 2021 Category: Opthalmology Tags: Original Study Source Type: research

Clinical outcomes of different subtypes of neovascular age-related macular degeneration during aflibercept treatment
Conclusion: All subtypes of neovascular age-related macular degeneration showed anatomical improvement and stabilization of visual function during intravitreal treatment. (Source: RETINA)
Source: RETINA - January 1, 2021 Category: Opthalmology Tags: Original Study Source Type: research

Quantitative optical coherence tomography angiography features of inactive macular neovascularization in age-related macular degeneration
Purpose: To compare quantitative optical coherence tomography angiography parameters between treatment-naïve quiescent macular neovascularizations (MNVs) and previously treated nonexudative Type 1 MNVs, in patients with age-related macular degeneration. Methods: The eyes included in the study were analyzed by fluorescein angiography, indocyanine green angiography, spectral-domain optical coherence tomography, and optical coherence tomography angiography. According to their medical history and multimodal imaging evaluation, Type 1 MNVs were divided into 2 groups: 1) treatment-naïve quiescent MNVs; 2) pr...
Source: RETINA - January 1, 2021 Category: Opthalmology Tags: Original Study Source Type: research

Intraretinal hyperreflective lines
Conclusion: The present series showed that intraretinal hyperreflective lines could occur in various inflammatory, degenerative, or tractional conditions. They could reflect a previously unrecognized reaction to various photoreceptor, Müller cell, and/or retinal pigment epithelium damage. (Source: RETINA)
Source: RETINA - January 1, 2021 Category: Opthalmology Tags: Original Study Source Type: research

The effect of elective cataract extraction by phacoemulsification in eyes with vitreomacular traction syndrome
Conclusion: The effect of CE in phakic eyes with known VMT varies significantly. In the current case series, every eye with VMT and Stage 2 or 3 macular hole ended up with Stage 4 macular hole, although the VMT did not change significantly in the eyes of diabetic patients. Studies with larger sample size are needed to further elucidate the impact of elective CE on VMT. (Source: RETINA)
Source: RETINA - January 1, 2021 Category: Opthalmology Tags: Original Study Source Type: research

OUTCOMES OF COMBINED PHACOEMULSIFICATION AND PARS PLANA VITRECTOMY FOR RHEGMATOGENOUS RETINAL DETACHMENT: A Comparative Study
Conclusion: Combined phacoemulsification and PPV is a safe and effective procedure to treat retinal detachment. The anatomical and functional results were comparable with those obtained with PPV and delayed cataract surgery. However, the refractive outcomes were less favorable and shifted toward myopia, especially in macula-off cases. (Source: RETINA)
Source: RETINA - January 1, 2021 Category: Opthalmology Tags: Original Study Source Type: research

Epidemiology of vitreomacular interface abnormalities using macular spectral-domain optical coherence tomography in an elderly population (the montrachet study)
Purpose: The aim of this study was to investigate the prevalence of vitreomacular interface abnormalities (VMIAs) and to identify associated factors in an elderly population in Europe. Methods: The MONTRACHET (Maculopathy Optic Nerve nuTRition neurovAsCular and HEarT diseases) Study is a population-based study, conducted in subjects older than 75 years. Vitreomacular adhesions, vitreomacular tractions, macular holes, epiretinal membranes, and macular cysts were assessed on spectral-domain optical coherence tomography examinations. The prevalence of VMIAs was estimated. We studied the association of demographic a...
Source: RETINA - January 1, 2021 Category: Opthalmology Tags: Original Study Source Type: research

Quantitative assessment of the foveal avascular zone using optical coherence tomography angiography before and after surgery for idiopathic epiretinal membrane
Purpose: To investigate, using optical coherence tomography angiography, the foveal avascular zone (FAZar), the FAZ perimeter (FAZp), the acircularity index of the FAZ (FAZai), and the density of vessels surrounding the FAZ (FAZvd) before and after idiopathic epiretinal membrane surgery, and associations of these parameters with postoperative best-corrected visual acuity, letter score gain, and central foveal thickness. Methods: We retrospectively reviewed preoperative and postoperative (sixth month) medical records of 28 eyes of 28 patients who undergone epiretinal membrane surgery and had an intact ellipsoid z...
Source: RETINA - January 1, 2021 Category: Opthalmology Tags: Original Study Source Type: research

Retinal sensitivity and vessel density after macular hole surgery with the superior inverted internal limiting membrane flap technique
Purpose: To evaluate retinal vessel density and retinal sensitivity (RS) after macular hole surgery with the superior inverted internal limiting membrane flap technique. Methods: Retrospective, observational case series. Twenty-one patients with idiopathic macular hole underwent 27-gauge vitrectomy with the superior inverted internal limiting membrane flap technique and triamcinolone acetonide. Measurements included RS, which was measured with microperimetry, as well as retinal vessel density in the superficial capillary plexus (SCP) and deep capillary plexus (DCP), which was measured with optical coherence tomo...
Source: RETINA - January 1, 2021 Category: Opthalmology Tags: Original Study Source Type: research

Comparison of the internal limiting membrane insertion technique and the inverted internal limiting membrane flap technique with vitrectomy to treat macular hole–associated retinal detachment
Conclusion: The inverted ILM flap technique was more effective in improving the postoperative BCVA in patients with MH-associated retinal detachment when compared with the ILM insertion technique. The preoperative BCVA and the ILM flap technique were independent prognostic factors for visual outcomes in patients with MH-associated retinal detachment. (Source: RETINA)
Source: RETINA - January 1, 2021 Category: Opthalmology Tags: Original Study Source Type: research

Assessing the ability of preoperative quantitative spectral-domain optical coherence tomography characteristics to predict visual outcome in idiopathic macular hole surgery
Conclusion: Increased MH minimum diameter, base diameter, base area, and choroidal hypertransmission are correlated with a poorer postoperative BCVA. Ellipsoid zone loss measurements were not consistently correlated with a BCVA. Choroidal hypertransmission width may be an easy-to-visualize predictive imaging biomarker in MH surgery. (Source: RETINA)
Source: RETINA - January 1, 2021 Category: Opthalmology Tags: Original Study Source Type: research

Early and late macular changes after the inverted internal limiting membrane flap technique for a full-thickness macular hole
Purpose: To describe the anatomic evolution of full-thickness macular hole closure after the inverted internal limiting membrane (ILM) flap technique. Methods: A retrospective review of 39 eyes (38 patients) with a full-thickness macular hole treated with the inverted ILM flap technique was performed. Ophthalmic examinations and imaging were performed preoperatively and postoperatively. Results: Macular changes in the early postoperative period included flap closure (15.4%), U-shaped closure (17.9%), V-shaped closure (33.3%), W-shaped closure (28.2%), gap closure (2.6%), and gap open (2.6%). Flap closure ...
Source: RETINA - January 1, 2021 Category: Opthalmology Tags: Original Study Source Type: research

THE ANGIOPOIETIN/TIE PATHWAY IN RETINAL VASCULAR DISEASES: A Review
Conclusion: Initial clinical evidence suggests a potential benefit of targeting the angiopoietin/Tie pathway and vascular endothelial growth factor-A over anti–vascular endothelial growth factor-A monotherapy alone, in part due to of the synergistic nature of the pathways. (Source: RETINA)
Source: RETINA - January 1, 2021 Category: Opthalmology Tags: Review Source Type: research

Usefulness of the proximity endoscope in vitrectomy for proliferative diabetic retinopathy
No abstract available (Source: RETINA)
Source: RETINA - November 24, 2020 Category: Opthalmology Tags: New Instruments Source Type: research

Diagnostic and Therapeutic Challenges
No abstract available (Source: RETINA)
Source: RETINA - November 24, 2020 Category: Opthalmology Tags: Diagnostic and Therapeutic Challenges Source Type: research

Altered blood and aqueous humor levels of asprosin, 4-hydroxynonenal, and 8-hydroxy-deoxyguanosine in patients with diabetes mellitus and cataract with and without diabetic retinopathy
Conclusion: These findings suggest that the measurement of asprosin, 4-HNE, and 8-OHdG levels may support clinicians in determining the risk of DRP development. (Source: RETINA)
Source: RETINA - November 24, 2020 Category: Opthalmology Tags: Original Study Source Type: research

EPIRETINAL FIBROSIS REMOVAL IN AN ARGUS II–IMPLANTED EYE: Histological Characteristics and Functional Results
Conclusion: Fibrosis can develop between the Argus II and the retina with increasing reduced function. Morphologic characteristics of the removed fibrosis suggested a pathogenesis based on an inflammatory process involved in a foreign body reaction with progressing connective tissue deposition leading to sclerosis. Adequate clinical follow-up is critical to successful removal of the fibrosis with reactivation of the Argus II function. (Source: RETINA)
Source: RETINA - November 24, 2020 Category: Opthalmology Tags: Original Study Source Type: research

HYPERAUTOFLUORESCENT SPOTS IN ACUTE OCULAR TOXOPLASMOSIS: A New Indicator of Outer Retinal Inflammation
Conclusion: Ocular toxoplasmosis may trigger a transient outer retinal disruption in eyes with marked inflammatory symptoms of the younger patients. (Source: RETINA)
Source: RETINA - November 24, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Optical coherence tomography angiography in patients with retinitis pigmentosa–associated cystoid macular edema
Conclusion: RP-CME was mostly located in the inner nuclear layer of the parafoveal macula, without vascular disruption in optical coherence tomography angiography. Our findings may support the hypothesis that the pathogenesis of RP with CME differs from retinal vascular CME triggered by compromised deep capillary plexus. (Source: RETINA)
Source: RETINA - November 24, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Intraocular pressure outcomes after surgery for rhegmatogenous retinal detachment in schwartz syndrome
Conclusion: Surgical management of rhegmatogenous retinal detachment resulted in significant reduction in IOP. At the final visit, 41% did not require any IOP-lowering medication or surgical intervention for IOP control. (Source: RETINA)
Source: RETINA - November 24, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Changes in choriocapillaris, sattler, and haller layer thicknesses in central serous chorioretinopathy after half-fluence photodynamic therapy
Purpose: To determinate the variation in thickness of the individual choroidal layers in patients with central serous chorioretinopathy treated with half-fluence photodynamic therapy. Methods: Twenty-two eyes were evaluated with spectral-domain optical coherence tomography. The images were taken before photodynamic therapy, 3 months, and 6 months after the treatment. Two investigators performed these measurements: 1) choroidal thickness (CT), 2) Haller layer thickness, defined as the most external layer containing a 100-μm vessel, and 3) choriocapillaris + Sattler layer (C&S). Nine measurements were taken...
Source: RETINA - November 24, 2020 Category: Opthalmology Tags: Original Study Source Type: research

ANATOMICAL AND FUNCTIONAL RESULTS OF INTRAVITREAL AFLIBERCEPT MONOTHERAPY FOR TYPE 1 RETINOPATHY OF PREMATURITY: One-Year Outcomes
Conclusion: Aflibercept is effective and well tolerated for the treatment of Type 1 retinopathy of prematurity; it is a potential treatment option as it achieves good anatomical, visual, and refractive outcomes. (Source: RETINA)
Source: RETINA - November 24, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Ultra–wide-field imaging and intravenous fundus fluorescein angiography in infants with retinopathy of prematurity
Conclusion: Ultra–wide-field imaging and intravenous fundus fluorescein angiography using Optos 200Tx are feasible in infants with ROP, which have the potential to screen, diagnose, and follow-up for ROP. (Source: RETINA)
Source: RETINA - November 24, 2020 Category: Opthalmology Tags: Original Study Source Type: research

PROGRESSION OF ABCA4-RELATED RETINOPATHY: Prognostic value of demographic, functional, genetic, and imaging parameters
Conclusion: Trial design based on specific shape-descriptive factors and patients' baseline characteristics and the adaption of the trial duration may provide potential benefits in required cohort size and absolute number of visits. (Source: RETINA)
Source: RETINA - November 24, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Spectral fundus autofluorescence excitation and emission in abca4-related retinopathy
Conclusion: By separation of the AF spectra, the remodeling of fluorophores and associated structural changes can be monitored over time indicating a novel and susceptible surrogate marker for disease progression and potential therapeutic effects. (Source: RETINA)
Source: RETINA - November 24, 2020 Category: Opthalmology Tags: Original Study Source Type: research

IDIOPATHIC FOVEAL HYPOPLASIA: Quantitative Analysis Using Optical Coherence Tomography Angiography
Purpose: To evaluate vascular density (VD), fractal dimension, and skeletal density on optical coherence tomography angiography in eyes with idiopathic foveal hypoplasia (IFH). Methods: Patients presenting with IFH to Creteil University Eye Clinic between January 2015 and October 2018 and age-matched healthy controls were retrospectively evaluated. Vascular density, skeletal density, and fractal dimension analyses were computed on optical coherence tomography angiography superficial capillary plexa (SCP) and deep capillary plexa (DCP) images on the whole image using a custom algorithm. Vascular density on the ce...
Source: RETINA - November 24, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Optical coherence tomography angiography features of focal choroidal excavation and the choroidal stroma variations with occurrence of excavation
Conclusion: Deep capillary plexus and choriocapillaris plexus were significantly altered in FCE patients. Moreover, choroidal stroma was significantly reduced in the areas closer to FCE compared to the surrounding choroid in patients, as well as compared to healthy controls, suggesting the hypothesis of weakening of the architectural support, creating a more friable point, which can favor FCE development. (Source: RETINA)
Source: RETINA - November 24, 2020 Category: Opthalmology Tags: Original Study Source Type: research

RISK OF AGE-RELATED MACULAR DEGENERATION IN PATIENTS WITH PERIODONTITIS: A Nationwide Population-Based Cohort Study
Purpose: Periodontitis is an inflammatory disease that results in loss of connective tissue and bone support. Evidence shows a possible relationship between periodontitis and age-related macular degeneration (AMD). Methods: This population-based cohort study was conducted using data from the National Health Insurance Research Database in Taiwan, with a 13-year follow-up, to investigate the risk of AMD in patients with periodontitis. The periodontitis cohort included patients with newly diagnosed periodontitis between 2000 and 2012. The nonperiodontitis cohort was frequency-matched with the periodontitis cohort b...
Source: RETINA - November 24, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Visual prognosis after pneumatic displacement of submacular hemorrhage according to age-related macular degeneration subtypes
This study compared the visual outcome after pneumatic displacement of submacular hemorrhage among patients with different subtypes of age-related macular degeneration (AMD). Methods: We retrospectively reviewed the medical records of 67 patients (67 eyes) who underwent treatment for submacular hemorrhage associated with AMD. All the patients underwent pneumatic displacement. Demographic parameters, visual acuity, and anatomical features were analyzed among AMD subtypes: typical AMD, polypoidal choroidal vasculopathy (PCV), and retinal angiomatous proliferation (RAP). Results: Among the eyes with submacular h...
Source: RETINA - November 24, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Diagnostic characteristics of polypoidal choroidal vasculopathy based on b-scan swept-source optical coherence tomography angiography and its interrater agreement compared with indocyanine green angiography
Conclusion: Polyp detection on B-scan OCTA demonstrates high accuracy and is comparable to that obtained on ICGA. B-scan OCTA could replace ICGA for the diagnosis of polypoidal choroidal vasculopathy. (Source: RETINA)
Source: RETINA - November 24, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Prevalence and risk factors for the development of physician-graded subretinal fibrosis in eyes treated for neovascular age-related macular degeneration
Purpose: To assess the prevalence and incidence of and risk factors for subretinal fibrosis (SRFi) in eyes with neovascular age-related macular degeneration (nAMD) that underwent vascular endothelial growth factor inhibitor treatment for up to 10 years. Methods: A cross-sectional and longitudinal analysis was performed on data from a neovascular age-related macular degeneration registry. The presence and location of SRFi were graded by the treating practitioner. Visual acuity, lesion characteristics (type, morphology, and activity), and treatment administered at each visit was recorded. Results: The preva...
Source: RETINA - November 24, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Real-color versus pseudo-color imaging of fibrotic scars in exudative age-related macular degeneration
Purpose: To compare the morphological characteristics of subretinal fibrosis in late age-related macular degeneration using multicolor (MC) imaging, color fundus photography (CFP), and ultra-widefield CFP (UWFCFP). Methods: Thirty-two eyes of 31 patients diagnosed with subretinal fibrosis complicating exudative age-related macular degeneration were included. Included eyes were imaged by MC, CFP, and UWFCFP. The overall ability to visualize fibrosis, its margins, and dissimilarity with surrounding atrophy was graded using a score (0: not visible, 1: barely visible, 2: mostly visible, and 3: fully visible) by two ...
Source: RETINA - November 24, 2020 Category: Opthalmology Tags: Original Study Source Type: research