Reply
No abstract available (Source: RETINA)
Source: RETINA - September 23, 2020 Category: Opthalmology Tags: Correspondence Source Type: research

Correspondence
No abstract available (Source: RETINA)
Source: RETINA - September 23, 2020 Category: Opthalmology Tags: Correspondence Source Type: research

Reply
No abstract available (Source: RETINA)
Source: RETINA - September 23, 2020 Category: Opthalmology Tags: Correspondence Source Type: research

Correspondence
No abstract available (Source: RETINA)
Source: RETINA - September 23, 2020 Category: Opthalmology Tags: Correspondence Source Type: research

Choroidal Venous Remodeling Documented by Long-Term Follow-up
No abstract available (Source: RETINA)
Source: RETINA - September 23, 2020 Category: Opthalmology Tags: Photo Essay Source Type: research

Segmental Choroidal Vasculitis in Nodular Posterior Scleritis Associated with Polyarteritis Nodosa
No abstract available (Source: RETINA)
Source: RETINA - September 23, 2020 Category: Opthalmology Tags: Photo Essay Source Type: research

Novel Multimodal Imaging and Volume Rendering of Type 3 Macular Neovascularization
No abstract available (Source: RETINA)
Source: RETINA - September 23, 2020 Category: Opthalmology Tags: Photo Essay Source Type: research

Diagnostic and Therapeutic Challenges
No abstract available (Source: RETINA)
Source: RETINA - September 23, 2020 Category: Opthalmology Tags: Diagnostic and Therapeutic Challenges Source Type: research

A NOVEL FINDING OF HYPERREFLECTIVE MATERIAL IN THE SILICONE-RETINA INTERFACE: An Optical Coherence Tomographic and Histopathological Study
Conclusion: This is the first report on hyperreflective material detected by spectral domain optical coherence tomography in the silicone-retina interphase in eyes with silicone oil tamponade. These findings may represent an inflammatory response to silicone oil exposure that may be the initial manifestation of a future proliferative process, warranting a rigorous follow-up protocol for affected patients. (Source: RETINA)
Source: RETINA - September 23, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Thicknesses of sclera and lamina cribrosa in patients with central retinal vein occlusion
Conclusion: Thicknesses of sclera and LC are increased in the CRVO, which may play a role in the pathogenesis of the disease. (Source: RETINA)
Source: RETINA - September 23, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Blood pressure variability in patients with branch retinal vein occlusion
Conclusion: Because the daytime, night-time, and 24-hour blood pressure variability in SBP, DBP, and ABP was significantly greater among patients with BRVO than among controls, blood pressure variability could factor into the pathogenesis of BRVO. (Source: RETINA)
Source: RETINA - September 23, 2020 Category: Opthalmology Tags: Original Study Source Type: research

THE ASSOCIATION BETWEEN CENTRAL SEROUS CHORIORETINOPATHY AND SLEEP APNEA: A Nationwide Population-Based Study
Purpose: To identify the association between sleep apnea (SA) and central serous chorioretinopathy (CSC). Methods: In this nationwide population-based study using the Taiwan National Health Insurance Database, we enrolled adult patients with a diagnosis of SA and matched each patient to 30 age- and gender-matched control subjects without any SA diagnosis. Using Poisson regression analyses, the incidence rate of CSC was compared between SA patients and control subjects. Results: A total of 10,753 SA patients and 322,590 control subjects were identified. After adjusting for age, gender, residency, income level, and c...
Source: RETINA - September 23, 2020 Category: Opthalmology Tags: Original Study Source Type: research

ANALYSIS OF THE VITREORETINAL SURGICAL FELLOWSHIP APPLICANT POOL: Publication Misrepresentations and Predictors of Future Academic Output
Conclusion: Unverifiable authorship among vitreoretinal surgical fellowship applicants is significant, affecting nearly one in 10 applicants with peer-reviewed publications. A reported desire to pursue academic medicine as listed on the fellowship application is a useful indicator for a future career in academics, and for increased number of peer-reviewed publications after fellowship. (Source: RETINA)
Source: RETINA - September 23, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Dark adaptation in macular telangiectasia type 2
Purpose: To evaluate dark adaptation (DA) in patients with macular telangiectasia Type 2 (MacTel). Methods: After a local photobleach (4 × 4° size, 83% bleach), DA was measured using a test stimulus (2° diameter) projected at 5° eccentricity horizontal from the foveal center within the temporal parafovea. Cone plateau, rod intercept time, and rod recovery rate (S2) were calculated from the resulting DA curves. Findings were correlated with disease stages (according to Gass and Blodi), the area of ellipsoid zone loss in optical coherence tomography, and macular pigment loss (“MP-Classes 1–...
Source: RETINA - September 23, 2020 Category: Opthalmology Tags: Original Study Source Type: research

SWEPT SOURCE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY, FLUORESCEIN ANGIOGRAPHY, AND INDOCYANINE GREEN ANGIOGRAPHY COMPARISONS REVISITED: Using a Novel Deep-Learning-Assisted Approach for Image Registration
Conclusion: We found no statistically significant differences between SSOCTA and FA and ICGA area measurements in patients with treatment-naive neovascular age-related macular degeneration after applying a deep-learning-assisted approach for image registration. These findings encourage a paradigm shift to using SSOCTA as a first-line diagnostic tool in neovascular age-related macular degeneration. (Source: RETINA)
Source: RETINA - September 23, 2020 Category: Opthalmology Tags: Original Study Source Type: research

AUTOMATED RETINAL LAYER SEGMENTATION AND THEIR THICKNESS PROFILES IN HEALTHY SUBJECTS: A Comparison of 55° Wide-field and Conventional 30° Spectral Domain-Optical Coherence Tomography
Conclusion: Fifty-five degree wide-field SD-OCT provides a good overview of the posterior pole and presents similar quantitative values as a standard 30° OCT lens. Therefore, thickness values are comparable when switching between these two lenses. (Source: RETINA)
Source: RETINA - September 23, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Handheld spectral domain optical coherence tomography findings of x-linked retinoschisis in early childhood
Conclusion: Early in life, the SD OCT findings in XLRS demonstrate differences in schisis location in fovea–parafoveal versus extrafoveal region, possible association between poor visual acuity and degree of ellipsoid zone disruption and decrease in central foveal thickness over time in this group. Furthermore, they illustrates that the pattern of XLRS in adults is already present in very young children, and unlike in older children and adults, those presenting with earlier disease may have a more aggressive course. Further studies in this early age group may provide more insights into treatment and prevention of p...
Source: RETINA - September 23, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Impaired dark adaptation associated with a diseased bruch membrane in pseudoxanthoma elasticum
Purpose: To characterize dark adaptation in patients with pseudoxanthoma elasticum, a systemic disease leading to calcification of elastic tissue including the Bruch membrane. Methods: In this prospective case–control study, dark adaptation thresholds were measured using a Goldmann-Weekers dark adaptometer. Additional assessments included best-corrected visual acuity testing, contrast sensitivity, low luminance deficit, and vision-related quality of life. Results: Dark adaptation thresholds were significantly higher, and adaptation periods were prolonged in patients with pseudoxanthoma elasticum (n = 35; 33 w...
Source: RETINA - September 23, 2020 Category: Opthalmology Tags: Original Study Source Type: research

INDOLENT, NONPROGRESSIVE, MULTIFOCAL CHOROIDAL LESIONS: A Presumed Benign Choroidal Lymphoid Disease
Conclusion: This entity is an indolent choroidal infiltrative disease. It resembles some cases of choroidal lymphoma and may represent an indolent lymphocytic infiltrate. (Source: RETINA)
Source: RETINA - September 23, 2020 Category: Opthalmology Tags: Original Study Source Type: research

EN-FACE OPTICAL COHERENCE TOMOGRAPHY IN PATIENTS WITH EPIRETINAL MEMBRANE: Intuitive Method for Predicting Functional Outcomes
Purpose: To evaluate the correlation between en-face optical coherence tomography (OCT) parameters and functional outcomes before and after idiopathic epiretinal membrane (ERM) surgery. Methods: This retrospective cohort study involved 80 eyes from 80 patients who underwent surgery for idiopathic ERM. Best-corrected visual acuity, metamorphopsia assessment (M-score), and OCT were assessed before surgery and six months after. The adhesive zone (A-zone) and retinal fold, a novel en-face OCT parameter reflecting inner retinal layer changes, were evaluated. Correlations between the area of A-zone and the number of retinal...
Source: RETINA - September 23, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Presence of peripheral lesions and correlation to macular perfusion, oxygenation and neurodegeneration in early type ii diabetic retinal disease
Purpose: The impact of peripheral retinal lesions (PL) visualized with ultra–wide-field imaging on diabetic retinopathy (DR) remains unclear. The purpose of this study was to assess the presence of PL and their association with macular microvasculopathy, metabolic dysfunction, and neurodegeneration in patients with Type II diabetes and early retinal disease. Methods: Forty-five degree color fundus (Topcon) and 200° ultra–wide-field images (Optos) were assessed for the presence and severity of DR. Lesions anterior to the 45° were considered peripheral. The foveal avascular zone area, perimeter and a...
Source: RETINA - September 23, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Effect of inverted internal limiting membrane flap on closure rate, postoperative visual acuity, and restoration of outer retinal layers in primary idiopathic macular hole surgery
Purpose: To investigate the role of an internal limiting membrane (ILM) flap in macular hole (MH) surgery on closure rate, visual acuity, and integrity of the outer retinal layers. Methods: Retrospective, nonrandomized interventional analysis in which 117 eyes of 117 patients were included who had undergone pars-plana vitrectomy (PPV) and gas tamponade for primary idiopathic MH>400 µm with either conventional ILM peeling or with inverted ILM flap technique at The Royal Liverpool University Hospital between January 2016 and April 2018. Main outcome measures were closure of MH, best-corrected visual acuity (BCV...
Source: RETINA - September 23, 2020 Category: Opthalmology Tags: Original Study Source Type: research

HUMAN AMNIOTIC MEMBRANE TO CLOSE RECURRENT, HIGH MYOPIC MACULAR HOLES IN PATHOLOGIC MYOPIA WITH AXIAL LENGTH OF ≥30 mm
Conclusion: The first case series of recurrent high myopic MH was reported, assessing the effectiveness of the human amniotic membrane plug to close recurrent MHs in pathologic myopia. All the cases were successful with encouraging best-corrected visual acuity recovery. (Source: RETINA)
Source: RETINA - September 23, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Autologous retinal transplantation as a primary treatment for large chronic macular holes
Conclusion: Autologous retinal transplantation may help rebuild the macular structure resulting in functional improvement for eyes with primary chronic large macular hole. (Source: RETINA)
Source: RETINA - September 23, 2020 Category: Opthalmology Tags: Original Study Source Type: research

FLUORESCENCE LIFETIME IMAGING OPHTHALMOSCOPY: Findings After Surgical Reattachment of Macula-Off Rhegmatogenous Retinal Detachment
Conclusion: Areas of previously detached retina exhibit significant fluorescence lifetime changes. We found a significant correlation of fluorescence lifetimes within the fovea with visual acuity after successful RRD repair. Our data suggests that the prolongation of fluorescence lifetimes in the fovea is mainly driven by loss of macular pigment. Therefore, fluorescence lifetime imaging ophthalmoscopy may be useful in the prediction of long-term functional outcomes after macula-off RRD surgery. (Source: RETINA)
Source: RETINA - September 23, 2020 Category: Opthalmology Tags: Original Study Source Type: research

A pilot clinical study of treating rhegmatogenous retinal detachment by silicone rubber balloon scleral buckling
Conclusion: This pilot study determined that foldable capsular vitreous body scleral buckling can be efficacious and safe for simple RRD. The results indicate that this surgery may be a novel alternative to the current extraocular procedures for simple RRD. (Source: RETINA)
Source: RETINA - September 23, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Analysis of time to failure after retinal detachment surgery
Purpose: To present the distribution of time to retinal redetachment in eyes undergoing retinal detachment surgery, using a method for adjusting time to outcome in eyes with silicone oil or heavy liquid tamponade (“oil-filled eyes”). Methods: Data from two Australian centers were used. Adjusted time to outcome was measured from the date of tamponade removal in oil-filled eyes, unless failure was diagnosed with tamponade in situ. Results: 188/1257 failures were identified (15.0%). Using unadjusted time to outcome, failures in oil-filled eyes occurred later than non–oil-filled eyes (median time to f...
Source: RETINA - September 23, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Patching retinal breaks with healaflow in 27-gauge vitrectomy for the treatment of rhegmatogenous retinal detachment
Purpose: To report the surgical outcomes of primary rhegmatogenous retinal detachment (RRD) repaired by 27-gauge pars plana vitrectomy combined with Healaflow patch and air tamponade. Methods: In an initial vitro experiment, we observed and compared the dissolution and displacement of the dispersion spots of 0.05-mL Healaflow and sodium hyaluronate. We then performed a prospective, interventional cohort study on 38 eyes in 37 consecutive patients with primary rhegmatogenous retinal detachment. All eyes underwent pars plana vitrectomy combined with Healaflow patch and air tamponade; the postoperative period did not inv...
Source: RETINA - September 23, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Supplemental scleral buckle in the era of small incision vitrectomy and wide-angle viewing systems
Purpose: To evaluate trends and outcomes of scleral buckle as adjunct to pars plana vitrectomy for management of retinal detachment. Methods: Retrospective case series including 300 consecutive cases of retinal detachment that underwent pars plana vitrectomy. The series was divided into three consecutive groups: Group A (first 100 cases), Group B (second 100 cases), and Group C (third 100 cases). Results: Three hundred eyes of 289 patients, mean age 61.0 years, were included in the study. The mean follow-up was 31.3 months for Group A, 28.5 months for Group B, and 12.0 months for Group C (P (Source: RETINA)
Source: RETINA - September 23, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Development of macular atrophy after pars plana vitrectomy for myopic traction maculopathy and macular hole retinal detachment in pathologic myopia
Conclusion: The development of MA can occur in 11% of highly myopic eyes after PPV for myopic traction maculopathy and macular hole retinal detachment. This postoperative MA might be a new complication of pathologic myopia. (Source: RETINA)
Source: RETINA - September 23, 2020 Category: Opthalmology Tags: Original Study Source Type: research

RELATIONSHIP BETWEEN PREOPERATIVE FOVEAL MICROSTRUCTURE AND VISUAL ACUITY IN MACULA-OFF RHEGMATOGENOUS RETINAL DETACHMENT: Imaging Analysis by Swept Source Optical Coherence Tomography
Purpose: To visualize foveal microstructures in macula-off rhegmatogenous retinal detachment using swept source optical coherence tomography preoperatively and postoperatively and to investigate the relationship between foveal microstructures and postoperative visual acuity. Methods: We retrospectively analyzed 42 eyes of 42 consecutive patients diagnosed with macula-off rhegmatogenous retinal detachment who underwent anatomically successful repair surgery and were followed up for 6 months. We used swept source optical coherence tomography to investigate the relationship between preoperative and postoperative continui...
Source: RETINA - September 23, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Swept-source optical coherence tomography angiography image compensation of the choriocapillaris induces artifacts
Conclusion: The findings of this study show that the use of a commonly used imaging compensation technique can have undesired effects on the image, and its use should be carefully considered. A model explaining the cause of such changes in the choriocapillaris swept-source optical coherence angiography images is presented. (Source: RETINA)
Source: RETINA - September 23, 2020 Category: Opthalmology Tags: Original Study Source Type: research

CHOROIDAL BLOOD FLOW: Review and Potential Explanation for the Choroidal Venous Anatomy Including the Vortex Vein System
Conclusion: Control of blood flow is critical in the choroid, and this control seems to extend to the venous outflow system. Abnormalities in venous outflow may critically affect function in predictable pathogenic mechanisms. (Source: RETINA)
Source: RETINA - September 23, 2020 Category: Opthalmology Tags: Review Source Type: research

Reply
No abstract available (Source: RETINA)
Source: RETINA - August 26, 2020 Category: Opthalmology Tags: Correspondence Source Type: research

Correspondence
No abstract available (Source: RETINA)
Source: RETINA - August 26, 2020 Category: Opthalmology Tags: Correspondence Source Type: research

Reply
No abstract available (Source: RETINA)
Source: RETINA - August 26, 2020 Category: Opthalmology Tags: Correspondence Source Type: research

Correspondence
No abstract available (Source: RETINA)
Source: RETINA - August 26, 2020 Category: Opthalmology Tags: Correspondence Source Type: research

Reply
No abstract available (Source: RETINA)
Source: RETINA - August 26, 2020 Category: Opthalmology Tags: Correspondence Source Type: research

Correspondence
No abstract available (Source: RETINA)
Source: RETINA - August 26, 2020 Category: Opthalmology Tags: Correspondence Source Type: research

Nummular Macular Depigmentation in Dandy–Walker Syndrome
No abstract available (Source: RETINA)
Source: RETINA - August 26, 2020 Category: Opthalmology Tags: Photo Essay Source Type: research

Diagnostic and Therapeutic Challenges
No abstract available (Source: RETINA)
Source: RETINA - August 26, 2020 Category: Opthalmology Tags: Diagnostic and Therapeutic Challenges Source Type: research

Vitreous prostaglandin e2 changes after topical administration of diclofenac 0.1%, indomethacin 0.5%, nepafenac 0.3%, and bromfenac 0.09%
Purpose: To evaluate the vitreous concentration of different nonsteroidal anti-inflammatory drugs (NSAIDs) after topical administration and the related prostaglandin E2 (PGE2) levels in patients undergoing pars plana vitrectomy. Methods: A prospective, randomized, investigator-masked study was performed. One hundred four patients scheduled for a pars plana vitrectomy for an epiretinal membrane or a macular hole were randomized to receive topical diclofenac 0.1%, indomethacin 0.5%, nepafenac 0.3%, bromfenac 0.09%, or placebo 3 days before surgery. At the beginning of surgery, a sample of undiluted vitreous was collecte...
Source: RETINA - August 26, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Phenotype-guided genetic testing of pediatric inherited retinal disease in the united arab emirates
Conclusion: Phenotype-guided genetic testing had a remarkable yield for this patient population. Recessive disease is often from homozygous mutations. Cone-dominated phenotypes are common. There are apparent founder mutations for several genes that could be used in a targeted genetic testing strategy. Molecular diagnosis is particularly important in affected children when inherited retinal dystrophy could be a sign of syndromic disease as proper earlier diagnosis minimizes potential extraocular morbidity. (Source: RETINA)
Source: RETINA - August 26, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Longitudinal study of rpe65-associated inherited retinal degenerations
Conclusion: All patients with RPE65-associated IRDs developed symptoms within the first year of life. Visual function in childhood and adolescence varied but deteriorated inevitably toward blindness after age 40. In this study, genotype was not predictive of clinical course. The variance in severity of disease could not be explained by double hits in other IRD genes. (Source: RETINA)
Source: RETINA - August 26, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Ten-year epidemiology of retinopathy of prematurity treatment in taiwan
Conclusion: In Taiwan, the incidence of the use of intravitreal anti-VEGF injection for treating ROP increased between 2002 and 2011. Laser treatment was less frequently used than intravitreal anti-VEGF injection in 2011. (Source: RETINA)
Source: RETINA - August 26, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Rates and risk factors for recurrence of retinopathy of prematurity after laser or intravitreal anti–vascular endothelial growth factor monotherapy
Conclusion: Laser, IVR, and IVB are effective for Type 1 ROP. Retinopathy of prematurity recurrence requiring re-treatment was encountered as late as 50 weeks of postmenstrual age after IVB or IVR but earlier after laser. Longer follow-up for infants treated with anti–vascular endothelial growth factor is needed, especially in patients with significant risk factors such as an early postmenstrual age at initial treatment, Zone I ROP, low Apgar score, and multiple births. (Source: RETINA)
Source: RETINA - August 26, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Comparison of projection-resolved optical coherence tomography angiography-based metrics for the early detection of retinal microvascular impairments in diabetes mellitus
Conclusion: Vessel density and fractal dimension from the skeletonized deep capillary network may be the most sensitive for detecting early retinal capillary loss in diabetes mellitus. (Source: RETINA)
Source: RETINA - August 26, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Optical coherence tomography angiography detects subclinical radial peripapillary capillary density reduction after plaque radiotherapy for choroidal melanoma
Purpose: To evaluate radial peripapillary capillary density (RPCD) in irradiated eyes without radiation papillopathy clinically. Methods: Patients treated with plaque radiotherapy for unilateral choroidal melanoma without radiation papillopathy clinically received optical coherence tomography and optical coherence tomography angiography imaging at ∼12- to 24-month follow-up. Comparison of RPCD globally and meridian closest to plaque and meridian farthest to plaque of irradiated versus nonirradiated eyes was performed. Results: Mean age was 55 years (n = 10). Mean largest basal diameter and thickness were 10.1 a...
Source: RETINA - August 26, 2020 Category: Opthalmology Tags: Original Study Source Type: research

Vasoproliferative tumors in intermediate uveitis
Conclusion: The presence of active intermediate uveitis accompanied by VPTs suggests the need for an aggressive uveitis treatment. (Source: RETINA)
Source: RETINA - August 26, 2020 Category: Opthalmology Tags: Original Study Source Type: research