Correspondence
No abstract available (Source: RETINA)
Source: RETINA - January 1, 2018 Category: Opthalmology Tags: Correspondence Source Type: research

Reply
No abstract available (Source: RETINA)
Source: RETINA - January 1, 2018 Category: Opthalmology Tags: Correspondence Source Type: research

Correspondence
No abstract available (Source: RETINA)
Source: RETINA - January 1, 2018 Category: Opthalmology Tags: Correspondence Source Type: research

Multiple Sub–Internal Limiting Membrane Hemorrhages With Double Ring Sign in Eyes With Valsalva Retinopathy
No abstract available (Source: RETINA)
Source: RETINA - January 1, 2018 Category: Opthalmology Tags: Photo Essay Source Type: research

RETINAL LASER AND PHOTOGRAPHY PRACTICE EYE MODEL: A Cost-Effective Innovation to Improve Training Through Simulation
No abstract available (Source: RETINA)
Source: RETINA - January 1, 2018 Category: Opthalmology Tags: New Instruments Source Type: research

Diagnostic and Therapeutic Challenges
No abstract available (Source: RETINA)
Source: RETINA - January 1, 2018 Category: Opthalmology Tags: Diagnostic and Therapeutic Challenges Source Type: research

Autologous Internal Limiting Membrane Fragment Transplantation for Rhegmatogenous Retinal Detachment Due to Paravascular or Juxtapapillary Retinal Breaks Over Patchy Chorioretinal Atrophy in Pathologic Myopia
No abstract available (Source: RETINA)
Source: RETINA - January 1, 2018 Category: Opthalmology Tags: Surgical Technique Source Type: research

The Efficacy of Superior Inverted Internal Limiting Membrane Flap Technique for the Treatment of Full-Thickness Macular Hole
No abstract available (Source: RETINA)
Source: RETINA - January 1, 2018 Category: Opthalmology Tags: Surgical Technique Source Type: research

ASSOCIATION STUDY BETWEEN POLYMORPHISMS OF THE p53 AND LYMPHOTOXIN ALPHA (LTA) GENES AND THE RISK OF PROLIFERATIVE VITREORETINOPATHY/RETINAL DETACHMENT IN A MEXICAN POPULATION
Conclusion: The C allele for rs1042522 in p53 was genetically associated with a higher risk for RD but not for PVR in this cohort. This is the first association study attempting replication of PVR-associated risk alleles in a nonwhite population. (Source: RETINA)
Source: RETINA - January 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

LONG-TIME OUTCOME IN PATIENTS TREATED WITH RANIBIZUMAB FOR DIABETIC MACULAR EDEMA: A 4-Year Study
Purpose: To investigate the long-time visual outcome in patients with diabetic macular edema treated with ranibizumab in an ordinary clinical setting. Methods: One hundred two eyes of 80 patients were followed for 4 years. All patients received a loading dose of 3 monthly ranibizumab 0.5-mg injections. From Month 3 to Month 48, patients received ranibizumab reinjections pro re nata based on disease activity. Results: Excluding deaths, the 4-year visit was completed by 82% of the study eyes. The best-corrected visual acuity improved by 6.6 Early Treatment Diabetic Retinopathy Study letters at 4 years (P (Source: RETINA)
Source: RETINA - January 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Choroidal thickness in diabetic retinopathy assessed with swept-source optical coherence tomography
Conclusion: Swept-source optical coherence tomography demonstrates a significant reduction of CT in PDR compared with controls. In the foveal region, the choroid appears to be thinner in DR eyes than in diabetic eyes without retinopathy. (Source: RETINA)
Source: RETINA - January 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Influence of vitrectomy surgery on the integrity of outer retinal layers in diabetic macular edema
Purpose: To investigate the influence of pars plana vitrectomy (PPV) on the integrity of photoreceptor layers in eyes with diabetic macular edema (DME) by using parallelism (a parameter that comprehensively reflects photoreceptor–retinal pigment epithelium [RPE] complex alterations) in spectral-domain optical coherence tomography (SD-OCT) imaging. Methods: A consecutive series of 64 eyes in 55 patients with diabetic macular edema who underwent pars plana vitrectomy were recruited into the study. Spectral-domain optical coherence tomography images were obtained preoperatively and 6 months after surgery. The morph...
Source: RETINA - January 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

LONGITUDINAL CHANGES IN THICKNESSES OF THE MACULA, GANGLION CELL–INNER PLEXIFORM LAYER, AND RETINAL NERVE FIBER LAYER AFTER VITRECTOMY: A 12-Month Observational Study
Conclusion: Transient increases in the thickness of the macula and GC-IPL were observed at 1 month after vitrectomy, and the postoperative RNFL thickness increased until 3 months after surgery, after which it returned to preoperative levels. There was no significant change in intraocular pressure or optic nerve head parameters before and after surgery. (Source: RETINA)
Source: RETINA - January 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Metamorphopsia and outer retinal morphologic changes after successful vitrectomy surgery for macula-off rhegmatogenous retinal detachment
Purpose: To evaluate the correlation between metamorphopsia and outer retinal morphologic changes after successful vitrectomy for rhegmatogenous retinal detachment (RRD). Methods: Forty eyes from 40 patients with macula-off (26 eyes) or macula-on (14 eyes) RRDs that underwent pars plana vitrectomy were included. Metamorphopsia was quantified with M-CHARTS. The relationship between the integrity of the outer retinal layers examined by spectral domain optical coherence tomography and metamorphopsia at 6 and 12 months postoperatively was evaluated. Results: Metamorphopsia was significantly more frequent in eyes with m...
Source: RETINA - January 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Factors associated with visual outcome after macula-off rhegmatogenous retinal detachment surgery
Purpose: To evaluate preoperative factors influencing the visual outcome and postoperative factors associated with the changes in visual acuity, after reattachment surgery to treat macula-off rhegmatogenous retinal detachment. Methods: A total of 180 eyes of 180 patients who underwent reattachment surgery to treat macula-off rhegmatogenous retinal detachment, and who were followed up for more than 12 months, were reviewed retrospectively. Preoperative and postoperative characteristics, including optical coherence tomography findings, were comprehensively analyzed using univariate and multivariate models to evaluate pr...
Source: RETINA - January 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

INTRAVITREAL OCRIPLASMIN IN CLINICAL PRACTICE: Predictors of Success, Visual Outcomes, and Complications
Conclusion: Proper case selection may facilitate successful pharmacologic vitreolysis with ocriplasmin, improve visual outcomes, and minimize potential complications. (Source: RETINA)
Source: RETINA - January 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

ACUTE ZONAL OCCULT OUTER RETINOPATHY: Structural and Functional Analysis Across the Transition Zone Between Healthy and Diseased Retina
Conclusion: The results of multimodal imaging clarified the TZ in acute zonal occult outer retinopathy. The TZ was outlined by a distinct high autofluorescence border that correlated with loss of the ellipsoid zone band on spectral-domain optical coherence tomography. However, in fundus areas that seemed healthy on fundus autofluorescence, thinning of the outer retinal layers and thickening of the retinal nerve fiber layer were observed near the TZ. The TZ was also characterized by a decrease in visual sensitivity. (Source: RETINA)
Source: RETINA - January 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

OPTICAL COHERENCE TOMOGRAPHY FINDINGS IN CYTOMEGALOVIRUS RETINITIS: A Longitudinal Study
Conclusion: There are two distinct patterns of chorioretinal involvement in CMV retinitis. SD-OCT is a useful tool in the diagnosis, management, and prediction of the outcome of CMV retinitis. (Source: RETINA)
Source: RETINA - January 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Subfoveal choroidal thickness and vascular diameter in active and resolved central serous chorioretinopathy
Purpose: To determine the subfoveal choroidal thickness and analyze Haller's layer, Sattler's layer, and large choroidal vessel diameter in eyes with active central serous chorioretinopathy (CSC) and after resolution of CSC. Methods: Ocular and clinical features of 32 eyes with CSC were analyzed retrospectively from October 2014 to September 2015. Subfoveal choroidal thickness and thicknesses of Haller's layer and Sattler's layer were measured in the active and resolved states. The diameter of the subfoveal choroidal hyporeflective lumen (i.e., the large choroidal vessel in Haller's layer) was also measured. Results:...
Source: RETINA - January 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Involvement of multiple molecular pathways in the genetics of ocular refraction and myopia
Conclusion: New biomedical technologies and better-designed studies will continue to refine our understanding of the genetics and molecular pathways of refractive error, and may lead to preventative and therapeutic measures to combat the myopia epidemic. (Source: RETINA)
Source: RETINA - January 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

How vitreomacular interface modifies the efficacy of anti-vegf therapy for myopic choroidal neovascularization
Conclusion: The data show that ranibizumab is effective in controlling mCNV activity when associated with vitreoretinal interface alterations. However, a visual recovery was observed only in patients with uncomplicated mCNV. (Source: RETINA)
Source: RETINA - January 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Ising model of choriocapillaris flow
Conclusion: This model is a working hypothesis, and as such can help predict system characteristics, evaluate conclusions drawn from studies, suggest new research questions, and provide a way of obtaining an estimate of behavior in which experimental data are not yet available. It may be possible to understand choriocapillaris blood flow in health and disease states by determining by observing deviations from an expected model. (Source: RETINA)
Source: RETINA - January 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Significant reduction of peripapillary choroidal thickness in patients with unilateral branch retinal vein occlusion
Purpose: To evaluate changes in peripapillary choroidal thickness in patients with branch retinal vein occlusion (BRVO) over 12 months, using spectral-domain optical coherence tomography with enhanced depth imaging. Methods: This retrospective, interventional case series included 20 treatment-naive patients with unilateral BRVO with at least 12 months follow-up. The peripapillary choroidal thickness was measured over 12 months. Results: In BRVO-affected eyes, the mean peripapillary choroidal thickness was 213.5 ± 51.7 μm (126.1[FIGURE DASH]326.9 μm) at baseline and 129.6 ± 39.3 μm (65.9[FIGUR...
Source: RETINA - January 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

POSTTRAUMATIC ENDOPHTHALMITIS: An 18-Year Case Series
Purpose: To describe the demographics, characteristics, management, and visual outcomes of eyes diagnosed with endophthalmitis after open globe injury. Methods: Retrospective cohort analysis of all patients diagnosed with endophthalmitis after open globe injury from 1997 to 2015 at University Hospital, Newark, NJ. Results: Twenty-six eyes were identified (all male patients; mean age: 37 ± 15 years). Cultures were positive in 16 eyes (62%), with Staphylococcus species (7 eyes, 44%) being the most common organism. Twelve eyes (46%) presented with open globe injury and concurrent endophthalmitis; 14 eyes (54%) ...
Source: RETINA - January 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Multimodal fundus imaging of outer retinal tubulations in choroidal osteoma patients
Conclusion: The results of this study suggest that age, the greatest tumor linear dimension, total tumor area, decalcification area, and the presence of intraretinal fluid and retinal pigment epithelium alterations within the foveola and central 1-mm region might be risk factors for ORT formation. Spectral-domain OCT combined with en face OCT provides comprehensive imaging information for ORTs in choroidal osteoma. (Source: RETINA)
Source: RETINA - January 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Characterizing photoreceptor changes in acute posterior multifocal placoid pigment epitheliopathy using adaptive optics
Conclusion: Irregularities in the reflectivity of the photoreceptor mosaic are visible on AOSLO even in inactive APMPPE lesions, where the photoreceptor bands on spectral domain optical coherence tomography have recovered. Adaptive optics scanning laser ophthalmoscopy combined with multimodal imaging has the potential to enhance our understanding of photoreceptor involvement in APMPPE. (Source: RETINA)
Source: RETINA - January 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Dynamism of dot subretinal drusenoid deposits in age-related macular degeneration demonstrated with adaptive optics imaging
Conclusion: Adaptive optics scanning laser ophthalmoscopy reveals that dot SDD, like drusen, are dynamic. (Source: RETINA)
Source: RETINA - January 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Two year outcomes of “treat and extend” intravitreal therapy using aflibercept preferentially for neovascular age-related macular degeneration
Purpose: To report 24-month outcomes of a treat and extend (T&E) regimen using aflibercept in eyes with neovascular age-related macular degeneration. Methods: This was a database observational study that included treatment-naive eyes with neovascular age-related macular degeneration tracked by the Fight Retinal Blindness! outcome registry completing 24 months of sole monotherapy with aflibercept treatment under a T&E regimen between November 1, 2012 and January 31, 2014. Locally weighted scatterplot smoothing curves were used to display visual acuity outcomes. Main outcome measures were change in visual acuity...
Source: RETINA - January 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Novel classification system for combined hamartoma of the retina and retinal pigment epithelium
Conclusion: A new clinical classification system is proposed for evaluating and managing patients with combined hamartoma of the retina and RPE. The zone and stage of combined hamartoma of the retina and RPE lesion will assist in determining follow-up interval and surgical intervention. Application of a uniform classification scheme will facilitate assessment and comparison of findings across different studies. (Source: RETINA)
Source: RETINA - January 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Pooled estimates of incidence of endophthalmitis after intravitreal injection of anti–vascular endothelial growth factor agents with and without topical antibiotic prophylaxis
Conclusion: Topical antibiotic after intravitreal injection of anti–vascular endothelial growth factor agents is associated with a higher risk of endophthalmitis. (Source: RETINA)
Source: RETINA - January 1, 2018 Category: Opthalmology Tags: Review Source Type: research

Retina, The Journal of Retinal and Vitreous Diseases 2017 Scientific Reviewers
No abstract available (Source: RETINA)
Source: RETINA - December 14, 2017 Category: Opthalmology Tags: Reviewers Source Type: research

Reply
No abstract available (Source: RETINA)
Source: RETINA - December 14, 2017 Category: Opthalmology Tags: Correspondence Source Type: research

Correspondence
No abstract available (Source: RETINA)
Source: RETINA - December 14, 2017 Category: Opthalmology Tags: Correspondence Source Type: research

Reply
No abstract available (Source: RETINA)
Source: RETINA - December 14, 2017 Category: Opthalmology Tags: Correspondence Source Type: research

Correspondence
No abstract available (Source: RETINA)
Source: RETINA - December 14, 2017 Category: Opthalmology Tags: Correspondence Source Type: research

Multiple Sub–Internal Limiting Membrane Hemorrhages With Double Ring Sign in Eyes With Valsalva Retinopathy
No abstract available (Source: RETINA)
Source: RETINA - December 14, 2017 Category: Opthalmology Tags: Photo Essay Source Type: research

RETINAL LASER AND PHOTOGRAPHY PRACTICE EYE MODEL: A Cost-Effective Innovation to Improve Training Through Simulation
No abstract available (Source: RETINA)
Source: RETINA - December 14, 2017 Category: Opthalmology Tags: New Instruments Source Type: research

Diagnostic and Therapeutic Challenges
No abstract available (Source: RETINA)
Source: RETINA - December 14, 2017 Category: Opthalmology Tags: Diagnostic and Therapeutic Challenges Source Type: research

Autologous Internal Limiting Membrane Fragment Transplantation for Rhegmatogenous Retinal Detachment Due to Paravascular or Juxtapapillary Retinal Breaks Over Patchy Chorioretinal Atrophy in Pathologic Myopia
No abstract available (Source: RETINA)
Source: RETINA - December 14, 2017 Category: Opthalmology Tags: Surgical Technique Source Type: research

The Efficacy of Superior Inverted Internal Limiting Membrane Flap Technique for the Treatment of Full-Thickness Macular Hole
No abstract available (Source: RETINA)
Source: RETINA - December 14, 2017 Category: Opthalmology Tags: Surgical Technique Source Type: research

ASSOCIATION STUDY BETWEEN POLYMORPHISMS OF THE p53 AND LYMPHOTOXIN ALPHA (LTA) GENES AND THE RISK OF PROLIFERATIVE VITREORETINOPATHY/RETINAL DETACHMENT IN A MEXICAN POPULATION
Conclusion: The C allele for rs1042522 in p53 was genetically associated with a higher risk for RD but not for PVR in this cohort. This is the first association study attempting replication of PVR-associated risk alleles in a nonwhite population. (Source: RETINA)
Source: RETINA - December 14, 2017 Category: Opthalmology Tags: Original Study Source Type: research

LONG-TIME OUTCOME IN PATIENTS TREATED WITH RANIBIZUMAB FOR DIABETIC MACULAR EDEMA: A 4-Year Study
Purpose: To investigate the long-time visual outcome in patients with diabetic macular edema treated with ranibizumab in an ordinary clinical setting. Methods: One hundred two eyes of 80 patients were followed for 4 years. All patients received a loading dose of 3 monthly ranibizumab 0.5-mg injections. From Month 3 to Month 48, patients received ranibizumab reinjections pro re nata based on disease activity. Results: Excluding deaths, the 4-year visit was completed by 82% of the study eyes. The best-corrected visual acuity improved by 6.6 Early Treatment Diabetic Retinopathy Study letters at 4 years (P (Source: RETINA)
Source: RETINA - December 14, 2017 Category: Opthalmology Tags: Original Study Source Type: research

Choroidal thickness in diabetic retinopathy assessed with swept-source optical coherence tomography
Conclusion: Swept-source optical coherence tomography demonstrates a significant reduction of CT in PDR compared with controls. In the foveal region, the choroid appears to be thinner in DR eyes than in diabetic eyes without retinopathy. (Source: RETINA)
Source: RETINA - December 14, 2017 Category: Opthalmology Tags: Original Study Source Type: research

Influence of vitrectomy surgery on the integrity of outer retinal layers in diabetic macular edema
Purpose: To investigate the influence of pars plana vitrectomy (PPV) on the integrity of photoreceptor layers in eyes with diabetic macular edema (DME) by using parallelism (a parameter that comprehensively reflects photoreceptor–retinal pigment epithelium [RPE] complex alterations) in spectral-domain optical coherence tomography (SD-OCT) imaging. Methods: A consecutive series of 64 eyes in 55 patients with diabetic macular edema who underwent pars plana vitrectomy were recruited into the study. Spectral-domain optical coherence tomography images were obtained preoperatively and 6 months after surgery. The morph...
Source: RETINA - December 14, 2017 Category: Opthalmology Tags: Original Study Source Type: research

LONGITUDINAL CHANGES IN THICKNESSES OF THE MACULA, GANGLION CELL–INNER PLEXIFORM LAYER, AND RETINAL NERVE FIBER LAYER AFTER VITRECTOMY: A 12-Month Observational Study
Conclusion: Transient increases in the thickness of the macula and GC-IPL were observed at 1 month after vitrectomy, and the postoperative RNFL thickness increased until 3 months after surgery, after which it returned to preoperative levels. There was no significant change in intraocular pressure or optic nerve head parameters before and after surgery. (Source: RETINA)
Source: RETINA - December 14, 2017 Category: Opthalmology Tags: Original Study Source Type: research

Metamorphopsia and outer retinal morphologic changes after successful vitrectomy surgery for macula-off rhegmatogenous retinal detachment
Purpose: To evaluate the correlation between metamorphopsia and outer retinal morphologic changes after successful vitrectomy for rhegmatogenous retinal detachment (RRD). Methods: Forty eyes from 40 patients with macula-off (26 eyes) or macula-on (14 eyes) RRDs that underwent pars plana vitrectomy were included. Metamorphopsia was quantified with M-CHARTS. The relationship between the integrity of the outer retinal layers examined by spectral domain optical coherence tomography and metamorphopsia at 6 and 12 months postoperatively was evaluated. Results: Metamorphopsia was significantly more frequent in eyes with m...
Source: RETINA - December 14, 2017 Category: Opthalmology Tags: Original Study Source Type: research

Factors associated with visual outcome after macula-off rhegmatogenous retinal detachment surgery
Purpose: To evaluate preoperative factors influencing the visual outcome and postoperative factors associated with the changes in visual acuity, after reattachment surgery to treat macula-off rhegmatogenous retinal detachment. Methods: A total of 180 eyes of 180 patients who underwent reattachment surgery to treat macula-off rhegmatogenous retinal detachment, and who were followed up for more than 12 months, were reviewed retrospectively. Preoperative and postoperative characteristics, including optical coherence tomography findings, were comprehensively analyzed using univariate and multivariate models to evaluate pr...
Source: RETINA - December 14, 2017 Category: Opthalmology Tags: Original Study Source Type: research

INTRAVITREAL OCRIPLASMIN IN CLINICAL PRACTICE: Predictors of Success, Visual Outcomes, and Complications
Conclusion: Proper case selection may facilitate successful pharmacologic vitreolysis with ocriplasmin, improve visual outcomes, and minimize potential complications. (Source: RETINA)
Source: RETINA - December 14, 2017 Category: Opthalmology Tags: Original Study Source Type: research

ACUTE ZONAL OCCULT OUTER RETINOPATHY: Structural and Functional Analysis Across the Transition Zone Between Healthy and Diseased Retina
Conclusion: The results of multimodal imaging clarified the TZ in acute zonal occult outer retinopathy. The TZ was outlined by a distinct high autofluorescence border that correlated with loss of the ellipsoid zone band on spectral-domain optical coherence tomography. However, in fundus areas that seemed healthy on fundus autofluorescence, thinning of the outer retinal layers and thickening of the retinal nerve fiber layer were observed near the TZ. The TZ was also characterized by a decrease in visual sensitivity. (Source: RETINA)
Source: RETINA - December 14, 2017 Category: Opthalmology Tags: Original Study Source Type: research

OPTICAL COHERENCE TOMOGRAPHY FINDINGS IN CYTOMEGALOVIRUS RETINITIS: A Longitudinal Study
Conclusion: There are two distinct patterns of chorioretinal involvement in CMV retinitis. SD-OCT is a useful tool in the diagnosis, management, and prediction of the outcome of CMV retinitis. (Source: RETINA)
Source: RETINA - December 14, 2017 Category: Opthalmology Tags: Original Study Source Type: research