Choroidal Nevus Regression in the Setting of Checkpoint Inhibition Immunotherapy
No abstract available (Source: RETINA)
Source: RETINA - May 1, 2022 Category: Opthalmology Tags: Photo Essay Source Type: research

Diagnostic and Therapeutic Challenges
No abstract available (Source: RETINA)
Source: RETINA - May 1, 2022 Category: Opthalmology Tags: Diagnostic and Therapeutic Challenges Source Type: research

Metagenomic next-generation sequencing detects pathogens in endophthalmitis patients
Purpose: To investigate the utility of metagenomic next-generation sequencing (mNGS) in identifying the pathogens in endophthalmitis. Methods: In this prospective study, 36 cases of endophthalmitis were recruited. All patients received surgical treatment and intraocular drug lavage. The samples of vitreous or aqueous humor were extracted for mNGS and microbiological culture. The diagnostic performance of pathogens was compared between mNGS and culture. Results: The positive rates of mNGS and culture were 88.89% (32/36) and 27.78% (10/36), respectively. There was a statistically significant difference betw...
Source: RETINA - May 1, 2022 Category: Opthalmology Tags: Original Study Source Type: research

AUTOSOMAL DOMINANT MÜLLER CELL SHEEN DYSTROPHY: Clinical, Histopathologic, and Genetic Assessment in an Extended Family With Long Follow-Up
Conclusion: To the best of our knowledge, this is the first family reported with this disorder. Our data support the hypothesis that autosomal dominant Müller cell dystrophy is a distinct retinal dystrophy affecting Müller cells. Mutations in transthyretin gene may manifest as a predominantly retinal disorder. (Source: RETINA)
Source: RETINA - May 1, 2022 Category: Opthalmology Tags: Original Study Source Type: research

Lawn trimmer–related open-globe injuries in taiwan
Conclusion: Our study provides a broad characterization of lawn trimmer–related open-globe injuries. The informative and diverse findings of IOFBs on CT scans will help clinicians detect and recognize IOFBs more precisely and perform the surgery without causing further damage. (Source: RETINA)
Source: RETINA - May 1, 2022 Category: Opthalmology Tags: Original Study Source Type: research

Surgical outcome and prognostic factors after ophthalmic surgery in abusive head trauma
Conclusion: The general visual prognosis was poor for patients with AHT needing vitrectomy, although a high rate of retinal attachment was observed. Optic nerve atrophy is a prognostic factor for poor visual outcomes in patients with AHT who received ophthalmic surgery. (Source: RETINA)
Source: RETINA - May 1, 2022 Category: Opthalmology Tags: Original Study Source Type: research

RETINAL DETACHMENT IN EYES WITH BOSTON TYPE 1 KERATOPROSTHESIS: Surgical Techniques and Mid-Term Outcomes
Conclusion: Modified pars plana vitrectomy techniques resulted in relatively good mid-term anatomical, functional, and retention rate outcomes, given the severity of RD at presentation and the numerous preoperative comorbidities of KPro eyes. (Source: RETINA)
Source: RETINA - May 1, 2022 Category: Opthalmology Tags: Original Study Source Type: research

ACQUIRED VITELLIFORM LESIONS: A Novel Finding in Eyes with Peripapillary Pachychoroid Syndrome
Conclusion: The novel association between peripapillary pachychoroid syndrome and acquired vitelliform lesions is characterized by the classic findings of both entities, and visual prognosis is accordingly good. (Source: RETINA)
Source: RETINA - May 1, 2022 Category: Opthalmology Tags: Original Study Source Type: research

Association of flow signals within polyps on optical coherence tomography angiography with treatment responses after combination therapy for polypoidal choroidal vasculopathy
Conclusion: Persistent flow signals within polyps on OCT angiography at 2 weeks after combination therapy suggest less effectiveness of the initial treatment. (Source: RETINA)
Source: RETINA - May 1, 2022 Category: Opthalmology Tags: Original Study Source Type: research

Noninvasive diagnostic strategy of ocular toxocariasis based on clinical features
Conclusion: A comprehensive strategy based on at least two out of three positive signs showed excellent sensitivity and specificity and could serve as a noninvasive and fast screening strategy for the clinical diagnosis of OT. (Source: RETINA)
Source: RETINA - May 1, 2022 Category: Opthalmology Tags: Original Study Source Type: research

Transcorneal electrical stimulation therapy may have a stabilization effect on multifocal electroretinography for patients with retinitis pigmentosa
Conclusion: The progression in multifocal electroretinography might be stabilized with TES. Further studies with larger sample sizes and a longer follow-up are needed to conclude that TES reduces retinitis pigmentosa progression. (Source: RETINA)
Source: RETINA - May 1, 2022 Category: Opthalmology Tags: Original Study Source Type: research

Optical coherence tomography angiography findings in pigmented paravenous chorioretinal atrophy
Conclusion: Optical coherence tomography angiography quantitative analyses in pigmented paravenous chorio-retinal atrophy demonstrate a specific impairment at the level of the deep capillary plexus, which could in turn bring about a thinning of ganglion cell complex and outer nuclear layer. The alterations at the level of the choriocapillaris and the choroid, in general, could then represent a secondary effect. (Source: RETINA)
Source: RETINA - May 1, 2022 Category: Opthalmology Tags: Original Study Source Type: research

LONGITUDINAL FOLLOW-UP OF CHOROIDAL GRANULOMAS WITH INDOCYANINE GREEN ANGIOGRAPHY AND OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY: A Lesion-Based Analysis
Conclusion: Different healing behaviors of choroidal granulomas were identified combining ICGA and OCTA analysis. Late ICGA hyper-fluorescent lesions may be the consequence of a possible fibrotic shift. Structural changes in the choroid may persist after active granulomas resolution resulting in persistent flow voids on OCTA. (Source: RETINA)
Source: RETINA - May 1, 2022 Category: Opthalmology Tags: Original Study Source Type: research

SHORT-TERM OUTCOMES AFTER INTERIM TREATMENT WITH BROLUCIZUMAB: A Retrospective Case Series of a Single Center Experience
Conclusion: Interim treatment with brolucizumab resulted in anatomical improvements in 41 eyes (41/51%, 80%) that were maintained in 22 of these eyes (22/41%, 54%) for at least 6 months after switching back to the original anti–vascular endothelial growth factor therapeutic. There were no corresponding significant changes in visual acuity. (Source: RETINA)
Source: RETINA - May 1, 2022 Category: Opthalmology Tags: Original Study Source Type: research

Macular pigment optical density assessed by heterochromatic flicker photometry in eyes affected by primary epiretinal membrane
Purpose: To compare macular pigment optical density (MPOD) in healthy eyes versus eyes affected by primary epiretinal membrane (ERM) in different stages and to assess the relation between MPOD and optical coherence tomography findings. Methods: Prospective cross-sectional study of 62 eyes of 62 patients affected by unilateral primary ERM. Contralateral healthy eyes from the same patients were used as a control group. Main outcome measures were MPOD, ERM stage, central foveal thickness (CFT), outer nuclear layer thickness (ONLT), integrity of outer retinal bands, and presence of central bouquet abnormalities. ...
Source: RETINA - May 1, 2022 Category: Opthalmology Tags: Original Study Source Type: research