HOLE-DOOR SIGN: A Novel Intraoperative Optical Coherence Tomography Feature Predicting Macular Hole Closure
Conclusion: Hole-door sign is a novel intraoperative finding that predicts postoperative Type-1 closure of macular hole. This may add to the utility of intraoperative optical coherence tomography in clinical practice. (Source: RETINA)
Source: RETINA - October 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Benefit of intraoperative optical coherence tomography for vitreomacular surgery in highly myopic eyes
Conclusion: In highly myopic eyes, iOCT could help assess undetected macular openings and otherwise posterior vitreous status and epiretinal structure peeling. (Source: RETINA)
Source: RETINA - October 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

The expanding clinical spectrum of choroidal excavation in macular dystrophies
Conclusion: Focal choroidal excavation can be infrequently encountered in patients with macular dystrophies. The presence of CNV may complicate FCE in these patients, and anti–vascular endothelial growth factor seems to be an effective treatment with no progression of FCE over time. (Source: RETINA)
Source: RETINA - October 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

HIGH-RISK INTRAOCULAR RETINOBLASTOMA: Comparison Between Asian Indians and Americans From Two Major Referral Centers
Purpose: To identify the differences in the clinical and histopathologic features in eyes with advanced intraocular retinoblastoma in a developing country (India) versus a developed country (USA). Methods: Retrospective study. Results: Of 524 patients with retinoblastoma who underwent primary enucleation, 331 were from India, and 193 were from the USA. Asian Indians were older at presentation (35 months vs. 29 months; P = 0.02), had thicker tumors (13.8 mm vs. 12.4 mm; P = 0.0001) compared with Americans. High-risk intraocular retinoblastoma was more common in Asian Indians with a 2-fold greater risk compared with ...
Source: RETINA - October 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

LARGE UVEAL MELANOMA (≥10 MM THICKNESS): Clinical Features and Millimeter-by-Millimeter Risk of Metastasis in 1311 Cases. The 2018 Albert E. Finley Lecture
Purpose: To analyze the clinical features and rate of metastatic disease in eyes with large (≥10 mm thickness) uveal melanoma. Design: Retrospective noncomparative case series. Participants: There were 1,311 consecutive patients. Methods: Retrospective medical chart review. Main outcome measures: Clinical features and rate of metastatic melanoma. Results: Of 1,311 patients with large melanoma, the mean age was 59 years (median 60, range 6–98 years) and 95% were white. Mean tumor basal dimension was 17 mm (median 17, range 7–25 mm), and mean tumor thickness was 12 mm (median 12, range 10&ndas...
Source: RETINA - October 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Intravitreal injection of aflibercept in patients with polypoidal choroidal vasculopathy: a 3-year follow-up
Conclusion: Intravitreal aflibercept was effective in improving the vision of patients with polypoidal choroidal vasculopathy, as evaluated at the 3-year follow-up. Fixed treatment might be an important factor influencing improvement in visual acuity. (Source: RETINA)
Source: RETINA - October 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Disease activity after development of large subretinal hemorrhage in polypoidal choroidal vasculopathy
Purpose: To investigate changes in disease activity after a large subretinal hemorrhage in polypoidal choroidal vasculopathy. Methods: Fifty-two polypoidal choroidal vasculopathy eyes with large subretinal hemorrhage (at initial presentation [n = 33, Group 1] or developed during follow-up [n = 19, Group 2]) were enrolled. Thirty polypoidal choroidal vasculopathy eyes without subretinal hemorrhage were enrolled as controls. All subretinal hemorrhages were treated with pneumatic displacement. Other active lesions were treated with intravitreal ranibizumab on an as-needed basis. Injection-free period, 1-year injection nu...
Source: RETINA - October 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

INNER CHOROIDAL FLOW SIGNAL ATTENUATION IN PACHYCHOROID DISEASE: Optical Coherence Tomography Angiography
Conclusion: Zones of reduced choriocapillaris flow are prevalent in eyes with pachychoroid disease. Approximately 60% of these zones anatomically correlate with pachyvessels. Inner choroidal ischemia seems related to the pathogenesis of pachychoroid diseases. (Source: RETINA)
Source: RETINA - October 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Association between choroidal caverns and choroidal vascular hyperpermeability in eyes with pachychoroid diseases
Purpose: To investigate the association between choroidal caverns, choroidal vascular hyperpermeability (CVH), and pachyvessels in eyes with pachychoroid disease. Methods: This was a retrospective review of swept-source optical coherence tomography and indocyanine green angiography imaging performed on eyes with pachychoroid disease. Results: Imaging from 21 eyes with pachychoroid disease entities (8 eyes with pachychoroid pigment epitheliopathy, 11 eyes with central serous chorioretinopathy, and 3 eyes with pachychoroid neovasculopathy) from 11 patients (mean 49.5 years, male/female: 10/1, all white) was available...
Source: RETINA - October 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Reduced choriocapillaris flow in eyes with type 3 neovascularization and age-related macular degeneration
Purpose: To study choriocapillaris (CC) flow in eyes with Type 3 neovascularization (NV) and age-related macular degeneration, using optical coherence tomography angiography analysis. Methods: In this multicenter, retrospective, observational study, we collected data from 21 patients with unilateral Type 3 NV and age-related macular degeneration, based on clinical examination, structural optical coherence tomography, and fluorescein angiography when available. An additional group of 20 nonneovascular age-related macular degeneration eyes with unilateral Type 1 or Type 2 NV due to age-related macular degeneration was i...
Source: RETINA - October 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Ultrasonographic findings in the vitreous of patients with age-related macular degeneration treated with intravitreal anti-vascular endothelial growth factor injections
Conclusion: These preliminary results indicate a proportional increase in ultrasonographic reflectivity of vitreous gel with the number of injections. (Source: RETINA)
Source: RETINA - October 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

RANIBIZUMAB AND AFLIBERCEPT FOR THE TREATMENT OF PIGMENT EPITHELIAL DETACHMENT IN NEOVASCULAR AGE-RELATED MACULAR DEGENERATION: Data from an Observational Study
Conclusion: Eyes with neovascular age-related macular degeneration and RPED showed significant functional and anatomical responses after 6 months of intravitreal anti–vascular endothelial growth factor injections. However, we found no significant difference in anatomical response or change in visual acuity between eyes treated with ranibizumab compared with aflibercept. Larger, prospectively designed, randomized studies with longer term follow-up may identify a difference between the two drugs that we did not detect. (Source: RETINA)
Source: RETINA - October 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

HISTOLOGY OF GEOGRAPHIC ATROPHY SECONDARY TO AGE-RELATED MACULAR DEGENERATION: A Multilayer Approach
Conclusion: The ELM descent sharply delimits an area of marked gliosis and near-total photoreceptor depletion clinically defined as Geographic atrophy (or outer retinal atrophy), indicating severe and potentially irreversible tissue damage. Degeneration of supporting tissues across this boundary is gradual, consistent with steady age-related change and suggesting that RPE and Müller cells subsequently respond to a threshold of stress. Novel clinical trial endpoints should be sought at age-related macular degeneration stages before intense gliosis and thick deposits impede therapeutic intervention. (Source: RETINA)
Source: RETINA - October 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Reliability of confocal white-light fundus imaging for measurement of retina pigment epithelial atrophy in age-related macular degeneration
Conclusion: Measurements of atrophy from C-CFP were similar to those obtained by FAF and F-CFP. The grading reproducibility for C-CFP, however, was better than that for F-CFP and approached the level of FAF imaging. The use of C-CFP as a tool for quantitatively monitoring atrophic age-related macular degeneration lesions warrants further study, particularly in the context of clinical trials. (Source: RETINA)
Source: RETINA - October 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Retinal–choroidal anastomosis in macular telangiectasia type 2
Purpose: To investigate the deep retinal vascular changes potentially present in macular telangiectasis Type 2 (MacTel 2) with projection resolved optical coherence tomography angiography including volume rendering. Methods: Retrospective consecutive evaluation of patients with MacTel 2 in a community-based retinal referral practice with a comprehensive ophthalmologic examination to include optical coherence tomography and projection-resolved optical coherence tomography angiography with volume rendering. Main outcome measures were the characterization of vessel presence and anatomical arrangement in the outer retina....
Source: RETINA - October 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Visual and anatomical outcomes after diabetic traction and traction-rhegmatogenous retinal detachment repair
Purpose: To evaluate visual and anatomical outcomes of diabetic tractional retinal detachment repaired with pars plana vitrectomy. Methods: Operative records were used to retrospectively identify all patients with tractional retinal detachments secondary to proliferative diabetic retinopathy surgically repaired with pars plana vitrectomy between November 1, 2009, and January 1, 2015 at the LAC + USC (Los Angeles County + University of Southern California) Medical Center. Results: A total of 403 eyes with diabetic tractional retinal detachment in 359 patients were included. Successful reattachment of the retina was ...
Source: RETINA - October 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Significant reduction of both peripapillary and subfoveal choroidal thickness after panretinal photocoagulation in patients with type 2 diabetes
Purpose: To evaluate changes in peripapillary choroidal thickness (PCT) and subfoveal choroidal thickness (SFCT) after panretinal photocoagulation (PRP) for diabetic retinopathy. Methods: This retrospective interventional study included 59 treatment-naive eyes of 33 patients who underwent PRP and completed ≥12 months of follow-up. Peripapillary choroidal thickness and SFCT were measured at baseline and 1, 3, 6, and 12 months post-PRP. Differences between baseline and 12 months (ΔSFCT and ΔPCT) and percentage changes (ΔSFCT or ΔPCT/baseline × 100%) were determined. Results: Mean SFCT...
Source: RETINA - October 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

CHANGES IN DIABETIC RETINOPATHY SEVERITY WHEN TREATING DIABETIC MACULAR EDEMA WITH RANIBIZUMAB: DRCR.net Protocol I 5-Year Report
Conclusion: Individuals receiving ranibizumab therapy for diabetic macular edema may have favorable changes in DR severity throughout a 5-year period concomitant with sequential reduction in anti–vascular endothelial growth factor therapy. (Source: RETINA)
Source: RETINA - October 1, 2018 Category: Opthalmology Tags: Original Study Source Type: research

PERSISTENT PLACOID MACULOPATHY: A Systematic Review
Conclusion: Precise disease pathophysiology of persistent placoid maculopathy has not been elucidated but most probably relates to selective choriocapillaris hypoperfusion/ischemia/vasculitis. Combination of anti–vascular endothelial growth factor injections and immunosuppressive medications may be effective in controlling disease activity and limiting development of sight-threatening complications. (Source: RETINA)
Source: RETINA - October 1, 2018 Category: Opthalmology Tags: Review Source Type: research

Reversal of Retinal Vascular Leakage and Arrest of Progressive Retinal Nonperfusion With Monthly Anti–Vascular Endothelial Growth Factor Therapy for Proliferative Diabetic Retinopathy
No abstract available (Source: RETINA)
Source: RETINA - August 23, 2018 Category: Opthalmology Tags: Photo Essay Source Type: research

Diagnostic and Therapeutic Challenges
No abstract available (Source: RETINA)
Source: RETINA - August 23, 2018 Category: Opthalmology Tags: Diagnostic and Therapeutic Challenges Source Type: research

INTRAOPERATIVE AND POSTOPERATIVE COMPLICATIONS IN PHACOVITRECTOMY FOR EPIRETINAL MEMBRANE AND MACULAR HOLE: A Clinical Audit of 1,000 Consecutive Eyes
Purpose: The aim of this study was to report the intraoperative and postoperative complications of phacovitrectomy for epiretinal membrane (ERM) and macular hole (MH). Methods: This was a retrospective audit of 1,052 phacovitrectomy operations (410 for ERM and 642 for MH) by the same surgical team between 1998 and 2017. Outcome measures included rates of intraoperative anterior segment and posterior segment complications such as posterior capsule rupture and retinal breaks. A subgroup analysis of 189 procedures in which postoperative complications were rigorously recorded was also undertaken. Results: The rate of p...
Source: RETINA - August 23, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Blindness related to presumed retinal toxicity after using perfluorocarbon liquid during vitreoretinal surgery
Conclusion: Presumed toxic batches of perfluorocarbon liquid may cause massive retinal toxicity. A rapid suspicion, a correct traceability of surgical products, and informing health authorities are fundamental to prevent further cases of toxicity. (Source: RETINA)
Source: RETINA - August 23, 2018 Category: Opthalmology Tags: Original Study Source Type: research

ENDOPHTHALMITIS AFTER PARS PLANA VITRECTOMY: Efficacy of Intraoperative Subconjunctival Antibiotics
Conclusion: Prophylactic subconjunctival antibiotics were not associated with a significantly reduced rate of post-PPV endophthalmitis. With consideration of emerging multidrug-resistant bacteria, routine prophylactic subconjunctival antibiotics may not be justified. (Source: RETINA)
Source: RETINA - August 23, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Temporal vascular arcade width and angle in high axial myopia
Purpose: Axial myopia is associated with elongation of the posterior ocular segment. The authors measured posterior fundus landmarks and assessed their associations with axial length. Methods: Using fundus photographs, the authors measured the vertical distance between the temporal superior and temporal inferior arterial arcade (VDA) and the angle kappa between the temporal arterial arcades among other morphometric variables. Results: The study included 456 eyes with a mean age of 61.2 ± 14.2 years (range: 13–88 years) and mean axial length of 29.4 ± 2.1 mm (range: 23.2–35.3 mm). Mean angl...
Source: RETINA - August 23, 2018 Category: Opthalmology Tags: Original Study Source Type: research

TREATMENT PATTERNS AND 2-YEAR VISION OUTCOMES WITH BEVACIZUMAB IN DIABETIC MACULAR EDEMA: An Analysis From a Large U.S. Integrated Health Care System
Conclusion: This is the largest U.S. clinical practice–based study of bevacizumab use in diabetic macular edema. Consistent with national studies, the frequency of injection was low. Average BCVA improvement was lower than in anti–vascular endothelial growth factor trials. Significant BCVA improvement was achieved in approximately 30% of patients with newly diagnosed diabetic macular edema. (Source: RETINA)
Source: RETINA - August 23, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Impact of long-term intravitreal anti–vascular endothelial growth factor on preexisting microstructural alterations in diabetic macular edema
Purpose: Evaluation of the influence of long-term intravitreal anti–vascular endothelial growth factor treatment on preexisting retinal microstructural alterations in patients with diabetic macular edema. Methods: Eyes with diabetic macular edema and a history of ≥ 20 intravitreal anti–vascular endothelial growth factor (aflibercept and/or ranibizumab) injections were included in this retrospective study. Primary outcome was the extent of disorganization of retinal inner layers, alterations at the outer plexiform layer/Henle fiber layer junction, disruption of external limiting membrane/ellipsoid zone, ...
Source: RETINA - August 23, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Value of fractal analysis of optical coherence tomography angiography in various stages of diabetic retinopathy
Conclusion: The optical coherence tomography angiography FD is significantly lower in both superficial and deep capillary plexuses in eyes with all stages studied of diabetic retinopathy. The results were more often significant for the deep capillary plexus. The use of fractal analysis provides an objective criterion to assess microvascular disease burden in diabetic retinopathy. (Source: RETINA)
Source: RETINA - August 23, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Asymmetric diabetic retinopathy progression in patients with axial anisometropia
Purpose: To investigate the differences in the progression of diabetic retinopathy (DR) in both eyes of patients with axial anisometropia. Methods: A retrospective review was conducted on diabetic patients who had different axial lengths (difference greater than 1 mm) in each eye. The primary objective of this study was to analyze the differences in the progression of DR in both eyes of patients with axial anisometropia. Fundus images (fluorescein angiography and photographs of the fundus covering the Early Treatment Diabetic Retinopathy Study seven fields) were graded using the Early Treatment Diabetic Retinopathy St...
Source: RETINA - August 23, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Changes in plasma vascular endothelial growth factor level after intravitreal injection of bevacizumab, aflibercept, or ranibizumab for diabetic macular edema
Purpose: The aim of this study was to investigate the changes in plasma vascular endothelial growth factor (VEGF) level depending on the severity of diabetic retinopathy (DR) or diabetic macular edema (DME) and after intravitreal injection of bevacizumab, aflibercept, or ranibizumab for treatment of DME. Methods: Plasma VEGF level was evaluated in 72 patients with DR and changes were measured in 42 patients with DME receiving intravitreal injections of bevacizumab, aflibercept, or ranibizumab at the initial injection. Results: There were no correlations between plasma VEGF level and the severity of DME or DR. Basel...
Source: RETINA - August 23, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Efficacy and frequency of intravitreal aflibercept versus bevacizumab for macular edema secondary to central retinal vein occlusion
Purpose: To compare the safety, efficacy, and frequency of intravitreal injection of aflibercept and bevacizumab for treatment of macular edema secondary to central retinal vein occlusion. Design: Prospective, comparative, randomized, interventional study. Patients and Methods: Eyes with macular edema secondary to central retinal vein occlusion were randomized between two groups according to the intravitreal injection used. Group A included eyes treated with intravitreal aflibercept, and Group B included eyes treated with intravitreal bevacizumab injections. The inclusion criteria were macular edema secondary to ce...
Source: RETINA - August 23, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Foveal avascular zone area after internal limiting membrane peeling for epiretinal membrane and macular hole compared with that of fellow eyes and healthy controls
Purpose: To measure the foveal avascular zone (FAZ) area after internal limiting membrane (ILM) peeling and to determine the factors significantly correlated with the FAZ area. Methods: This was a retrospective, observational, and cross-sectional study. The affected and normal fellow eyes of 102 patients with unilateral macular diseases and 169 healthy subjects were studied. The patients underwent successful vitrectomy with internal limiting membrane peeling for an epiretinal membrane (n = 56) or a macular hole (n = 46). The superficial FAZ area and average foveal (within 1 mm) thickness were measured. The main outcom...
Source: RETINA - August 23, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Arcuate nerve fiber layer changes after internal limiting membrane peeling in idiopathic epiretinal membrane
Purpose: To analyze the relationship between swelling of the arcuate nerve fiber layer (SANFL) and long-term decrease of retinal nerve fiber layer thickness after internal limiting membrane peeling for idiopathic epiretinal membrane, and to investigate if SANFL is related to a mechanical surgical damage. Methods: Prospective, interventional consecutive case series of 46 eyes that underwent combined epiretinal membrane/internal limiting membrane peeling for idiopathic epiretinal membrane. Infrared, blue autofluorescence, color fundus imaging and measurement of retinal nerve fiber layer thickness in six peripapillary se...
Source: RETINA - August 23, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Comparative analysis of retinal reattachment surgery with or without internal limiting membrane peeling to prevent postoperative macular pucker
Conclusion: Internal limiting membrane peeling during pars plana vitrectomy for rhegmatogenous retinal detachment significantly reduces ERM formation in the postoperative period and is associated with better visual and anatomical outcomes. (Source: RETINA)
Source: RETINA - August 23, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Imaging of pigment epithelial detachments with optical coherence tomography angiography
Conclusion: Our proposed two-step approach of OCTA interpretation, first using cross-sectional OCTA and then en face OCTA, may allow the detection of vascularization within PEDs and, in some cases, reduce the need for conventional angiography. Increased awareness about potential artifacts and limitations of OCTA may help clinicians interpret OCTA more accurately. (Source: RETINA)
Source: RETINA - August 23, 2018 Category: Opthalmology Tags: Original Study Source Type: research

IDENTIFYING FEATURES OF EARLY AND LATE AGE-RELATED MACULAR DEGENERATION: A Comparison of Multicolor Versus Traditional Color Fundus Photography
Conclusion: Multicolor retinal imaging allowed for improved detection and definition of AMD features. (Source: RETINA)
Source: RETINA - August 23, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Macular atrophy and macular morphology in aflibercept-treated neovascular age-related macular degeneration
Conclusion: Macular atrophy developed in about 10% of eyes with neovascular age-related macular degeneration during 12 months of treatment with a fixed regimen of aflibercept. Intraretinal fluid and subfoveal choroidal thickness seem to be predictors for development of macular atrophy after anti-vascular endothelial growth factor (VEGF) therapy. (Source: RETINA)
Source: RETINA - August 23, 2018 Category: Opthalmology Tags: Original Study Source Type: research

The natural history of full-field stimulus threshold decline in choroideremia
Purpose: To evaluate full-field sensitivity thresholds (FSTs) across a wide range of choroideremia (CHM) disease stages and to determine their applicability as functional endpoints for CHM clinical trials. Methods: Thirty CHM subjects (60 eyes) and 50 healthy controls (50 eyes) underwent FST testing under dark-adapted conditions to determine rod- and cone-mediated FSTs. Central retinal structure and function were assessed using fundus autofluorescence and microperimetry. Correlation and regression analyses were performed to compare FST responses with the residual area of retinal pigment epithelium in the peri- and par...
Source: RETINA - August 23, 2018 Category: Opthalmology Tags: Original Study Source Type: research

SCLERAL PITS IN CHOROIDEREMIA: Implications for Retinal Gene Therapy
We report a novel finding on spectral domain optical coherence tomography in patients with choroideremia, which we describe as scleral pits (SCPs). Methods: Cross-sectional observational case series of 36 patients with choroideremia, who underwent ophthalmic examination and multimodal imaging, including optical coherence tomography of the macula. Optical coherence tomography images were reviewed for SCP, which were defined as discrete tracts of hyporeflectivity that traverse the sclera with or without the involvement of Bruch membrane, retinal pigment epithelium, and retina. Unpaired two-tailed t-test with Welch correct...
Source: RETINA - August 23, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Long-term follow-up of patients with choroideremia with scleral pits and tunnels as a novel observation
Conclusion: Choroideremia is a severely debilitating disease showing a rapid decline of visual acuity generally after the age of 35, but a more gradual decline for other abnormalities. (Source: RETINA)
Source: RETINA - August 23, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Prophylactic preoperative laser retinopexy does not reduce the occurrence of rhegmatogenous retinal complications in macular surgery
Conclusion: Preoperative prophylactic peripheral laser retinopexy does not seem to offer an added benefit in the prevention of intraoperative and postoperative rhegmatogenous events. (Source: RETINA)
Source: RETINA - August 23, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Prevalence of foveolar lucency with different gas tamponades in surgically closed macular holes assessed by spectral domain optical coherence tomography
Conclusion: Temporary FL is a highly prevalent feature in successfully closed macular holes. Eyes treated with C3F8 gas had lower rates of FL at Month 1 than C2F6 and SF6-treated eyes. The presence of FL in closed holes does not seem to have any effect on the visual outcomes. (Source: RETINA)
Source: RETINA - August 23, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Lean six sigma techniques to improve ophthalmology clinic efficiency
Conclusion: Manufacturing industry techniques, such as Lean and Six Sigma, can be used to improve patient care, minimize waste, and enhance patient and staff satisfaction in outpatient clinics. (Source: RETINA)
Source: RETINA - August 23, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Comparison of optical coherence tomography angiographic changes after anti–vascular endothelial growth factor therapy alone or in combination with photodynamic therapy in polypoidal choroidal vasculopathy
Conclusion: Longitudinal optical coherence tomography angiography demonstrates more significant reduction in lesion flow and pachyvessels in the short term after combination therapy than after monotherapy, although visual and structural OCT showed similar improvement. (Source: RETINA)
Source: RETINA - August 23, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Indocyanine green angiography of pachychoroid pigment epitheliopathy
Purpose: To compare choroidal hyperpermeability and vessel density between eyes with central serous chorioretinopathy (CSC), those with pachychoroid pigment epitheliopathy (PPE) and those with uncomplicated pachychoroid (UCP). Methods: We retrospectively reviewed indocyanine green angiography images of 60 patients with unilateral active CSC who had PPE (36 eyes) or UCP (24 eyes) in their fellow eyes. We used color thresholding of indocyanine green angiography images to determine choroidal vessel density. Results: The mean choroidal thickness of eyes with CSC was greater than that of eyes with PPE or UCP, but this d...
Source: RETINA - August 23, 2018 Category: Opthalmology Tags: Original Study Source Type: research

Peripapillary pachychoroid syndrome
Purpose: To describe the features of peripapillary pachychoroid syndrome (PPS), a novel pachychoroid disease spectrum (PDS) entity. Methods: Medical records of 31 eyes (16 patients) with choroidal thickening associated with intraretinal and/or subretinal fluid in the nasal macula extending from the disk were reviewed (patients with PPS). Choroidal thickness was compared with 2 age-matched cohorts: typical PDS (17 eyes with central serous chorioretinopathy or pachychoroid neovasculopathy) and 19 normal eyes. Results: The patients with PPS were 81% men aged 71 ± 7 years. Peripapillary pachychoroid syndrome eye...
Source: RETINA - August 23, 2018 Category: Opthalmology Tags: Original Study Source Type: research

ASSOCIATION OF OBSTRUCTIVE SLEEP APNEA WITH CENTRAL SEROUS CHORIORETINOPATHY AND CHOROIDAL THICKNESS: A Systematic Review and Meta-Analysis
Conclusion: In summary, our results suggest that patients with CSCR are more likely to have OSA, and that moderate/severe OSA is associated with smaller subfoveal choroidal measurements on enhanced depth imaging optical coherence tomography. (Source: RETINA)
Source: RETINA - August 23, 2018 Category: Opthalmology Tags: Review Source Type: research

Is It Time to Abandon Subconjunctival Antibiotics following Pars Plana Vitrectomy?
No abstract available (Source: RETINA)
Source: RETINA - August 23, 2018 Category: Opthalmology Tags: Editorial Source Type: research

Reply
No abstract available (Source: RETINA)
Source: RETINA - August 1, 2018 Category: Opthalmology Tags: Correspondence Source Type: research