Nanovitreoretinal Subretinal Gateway Device to Displace Submacular Hemorrhage: Access to the Subretinal Space Without Vitrectomy
No abstract available (Source: RETINA)
Source: RETINA - October 25, 2022 Category: Opthalmology Tags: Surgical Technique Source Type: research

Closed Continuous-Loop Suture: A Novel Surgical Technique for Transscleral Fixation of Intraocular Lenses
No abstract available (Source: RETINA)
Source: RETINA - October 25, 2022 Category: Opthalmology Tags: Surgical Technique Source Type: research

Application of Modified Silicone Oil Retention Sutures in Traumatic Aphakic Eyes With Iris Loss
No abstract available (Source: RETINA)
Source: RETINA - October 25, 2022 Category: Opthalmology Tags: Surgical Technique Source Type: research

Macular blood flow changes in branch retinal vein occlusion examined by optical coherence tomography angiography variable interscan time analysis
Conclusion: In eyes with branch retinal vein occlusion, optical coherence tomography angiography variable interscan time analysis facilitated the detection of retinal blood flow changes that might be predictive for the recurrence of macular edema. (Source: RETINA)
Source: RETINA - October 25, 2022 Category: Opthalmology Tags: Original Study Source Type: research

Locational agreement of near-infrared autofluorescence with choroidal vascular hyperpermeability in central serous chorioretinopathy
Conclusion: Hypoautofluorescent findings revealed on NIRAF imaging, especially after binarization processing, corresponded well with CVH sites. These multimodal imaging results may help investigate the anatomical or locational characteristics of CVH in patients with central serous chorioretinopathy. (Source: RETINA)
Source: RETINA - October 25, 2022 Category: Opthalmology Tags: Original Study Source Type: research

Long-term effects of anti-vegf monotherapy for retinopathy of prematurity on the retinal and refractive development of eye
Conclusion: All the anti-VEGF agents provided similar adequate axial and refractive development as well as similar abnormal vascular development in the peripheral retina. The long-term impact of this abnormally vascularized peripheral retina is a curiosity issue. From this point of view, it is an important need to determine the follow-up period and method after the anti-VEGF treatment for ROP. (Source: RETINA)
Source: RETINA - October 25, 2022 Category: Opthalmology Tags: Original Study Source Type: research

Assessments of macular function by focal macular electroretinography and static perimetry in eyes with retinitis pigmentosa
Purpose: To assess the macular function by focal macular electroretinography and static perimetry in eyes with retinitis pigmentosa. Methods: Eighty-eight eyes of 88 retinitis pigmentosa patients were analyzed. The relationships between the focal macular electroretinography components and the mean deviations (MDs) of the Humphrey Field Analyzer 10-2 were determined. Spectral-domain optical coherence tomography was used to determine the integrity of the ellipsoid zone (EZ) and the interdigitation zone. Results: Forward–backward stepwise regression analyses showed that the amplitudes (r = 0.45, P (Source: RETINA)
Source: RETINA - October 25, 2022 Category: Opthalmology Tags: Original Study Source Type: research

Topical carbonic anhydrase inhibitors in the long-term treatment of juvenile x-linked retinoschisis
Purpose: To describe the response to long-term topical dorzolamide treatment in patients with juvenile X-linked retinoschisis and cystic-like foveal lesions. Methods: This was a retrospective interventional case series that included 18 eyes of 10 patients with genetically confirmed juvenile X-linked retinoschisis examined at the Cleveland Clinic Cole Eye Institute, a tertiary referral center, between 2005 and 2021. Patients were treated with topical 2% dorzolamide two to three times daily in both eyes. Two eyes were excluded because of retinal detachment. Primary outcome measures were logarithm of minimum angle ...
Source: RETINA - October 25, 2022 Category: Opthalmology Tags: Original Study Source Type: research

Perivascular flower-bud-like lesions on en face optical coherence tomography angiography in patients with vitreoretinal lymphoma
Conclusion: PFBLs are characteristic imaging findings of vitreoretinal lymphoma and may facilitate an early diagnosis of vitreoretinal lymphoma, which would in turn lead to more timely and effective treatment. (Source: RETINA)
Source: RETINA - October 25, 2022 Category: Opthalmology Tags: Original Study Source Type: research

Optical coherence tomography findings in choroidal melanoma-associated subretinal fluid
Purpose: To report optical coherence tomography findings of choroidal melanoma with subretinal fluid (SRF). Methods: Single-center, retrospective review of spectral-domain optical coherence tomography in treatment-naive choroidal melanoma with associated SRF presenting between July 2009 and August 2021. Results: Of 236 included patients, choroidal melanoma was small (n = 98, 41.5%), medium (n = 99, 41.9%), or large (n = 39, 16.5%). The most common optical coherence tomography feature was ellipsoid zone loss/disruption (n = 174, 73.7%), with unique features of bacillary layer detachment (n = 67, 28.4%), an...
Source: RETINA - October 25, 2022 Category: Opthalmology Tags: Original Study Source Type: research

Fluidic performance of a dual-action vitrectomy probe compared with a single-action probe
Purpose: To assess flow rates, nearfield effects, and traction of a dual-cutting 20,000 cpm vitrectomy probe (HYPERVIT, Alcon) versus a single-cutting 10,000 cpm probe (Advanced ULTRAVIT, Alcon). Methods: Flow rates were evaluated for 25+ and 27+ gauge probes using balanced salt solution or porcine cadaver vitreous (biased open, 50/50, and biased closed duty cycles). Probes were suspended in an open beaker, and flow rates were calculated using a precision balance. Nearfield effects and flow pulsatility were assessed using a validated simulation model based on experimental microparticle image velocimetry. Tractio...
Source: RETINA - October 25, 2022 Category: Opthalmology Tags: Original Study Source Type: research

Optical coherence tomography features in idiopathic noninfectious intermediate, posterior, or panuveitis
Conclusion: With initiation of treatment, the central macular thickness, intraretinal fluid, subretinal fluid, and ellipsoid zone en-face abnormalities improved over time, whereas the number of cases with epiretinal membrane increased among eyes with idiopathic intermediate, posterior, and panuveitis. Presence of ellipsoid zone en-face abnormalities at presentation may be associated with worse visual acuity. (Source: RETINA)
Source: RETINA - October 25, 2022 Category: Opthalmology Tags: Original Study Source Type: research

RISK OF INTRAOCULAR INFLAMMATION AFTER INJECTION OF ANTIVASCULAR ENDOTHELIAL GROWTH FACTOR AGENTS: A Meta-analysis
Conclusion: There was no difference in the risk of severe sight-threatening IOI outcomes between intravitreal antivascular endothelial growth factor agents. There was a significantly higher risk of generalized IOI after brolucizumab relative to aflibercept. Our results alongside other recent safety findings suggest the need for further investigation in the risk–benefit profile of brolucizumab for the treatment of neovascular age-related macular degeneration. (Source: RETINA)
Source: RETINA - October 25, 2022 Category: Opthalmology Tags: Original Study Source Type: research

Culture positivity rates of deep vitreous biopsy under air vis-À-vis conventional anterior vitreous biopsy in endogenous endophthalmitis
Purpose: To describe the comparison of the culture positivity rates of deep vitreous biopsy under air and conventional anterior vitreous biopsy in endogenous endophthalmitis. Materials: A retrospective, consecutive, comparative series including cases of endogenous endophthalmitis from January 2014 to January 2021. They were divided into those where conventional anterior vitreous biopsy was taken and those where a deep biopsy was taken under air (DBA group). The culture positivity rate among the two groups was compared, and factors affecting the same were analyzed by a regression analysis. Results: There w...
Source: RETINA - October 25, 2022 Category: Opthalmology Tags: Original Study Source Type: research

Effect of physician face mask use on postinjection endophthalmitis
Purpose: To examine the impact of physician face mask use on the rates and outcomes of postinjection endophthalmitis. Methods: A multicenter retrospective, comparative cohort study comparing endophthalmitis rate and visual acuity of eyes that developed endophthalmitis after antivascular endothelial growth factor injections at Mayo Clinic Rochester (MCR) and at Mayo Clinic Health System sites depending on physician masking. Results: A total of 164,824 injections were performed at MCR and Mayo Clinic Health System sites. Of these, 66,098 injections were in the no mask group and 98,726 injections were in the...
Source: RETINA - October 25, 2022 Category: Opthalmology Tags: Original Study Source Type: research