A polymorphism in the glucocorticoid receptor gene is associated with refractory hypotension in premature infants
Glucocorticoids play an important role in endocrine control. The association of glucocorticoid receptor (GR) gene polymorphisms with altered sensitivity to glucocorticoid therapy has been reported in adults. However, there are few such reports in infants. The present study analyzed the prevalence of four GR polymorphisms in preterm infants born before 30 weeks of gestation and determined the associations between these polymorphisms and clinical outcomes in the infants. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - October 21, 2017 Category: Perinatology & Neonatology Authors: Kei Ogasawara, Maki Sato, Koichi Hashimoto, Takashi Imamura, Hayato Go, Mitsuaki Hosoya Tags: Original Article Source Type: research

Phenotypical characterization of human rhinovirus infections in severely premature children
Human Rhinovirus (HRV) has been identified as the most common cause of acute respiratory infections and hospitalizations in premature children. It is unclear if premature children are more susceptible to HRV due to their decreased pulmonary reserve or because they have enhanced lower airway reactivity to HRV. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - October 21, 2017 Category: Perinatology & Neonatology Authors: Geovanny F. Perez, Bassem Kurdi, Rosemary Megalaa, Krishna Pancham, Shehlanoor Huseni, Natalia Isaza, Carlos E. Rodriguez-Martinez, Dinesh Pillai, Gustavo Nino Tags: Original Article Source Type: research

A polymorphism in the glucocorticoid receptor gene is associated with refractory hypotension in premature infants
Glucocorticoids play an important role in endocrine control. The association of glucocorticoid receptor (GR) gene polymorphisms with altered sensitivity to glucocorticoid therapy has been reported in adults. However, there are few such reports in infants. The present study analyzed the prevalence of four GR polymorphisms in preterm infants born before 30 weeks of gestation and determined the associations between these polymorphisms and clinical outcomes in the infants. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - October 21, 2017 Category: Perinatology & Neonatology Authors: Kei Ogasawara, Maki Sato, Koichi Hashimoto, Takashi Imamura, Hayato Go, Mitsuaki Hosoya Tags: Original Article Source Type: research

Phenotypical characterization of human rhinovirus infections in severely premature children
Human Rhinovirus (HRV) has been identified as the most common cause of acute respiratory infections and hospitalizations in premature children. It is unclear if premature children are more susceptible to HRV due to their decreased pulmonary reserve or because they have enhanced lower airway reactivity to HRV. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - October 21, 2017 Category: Perinatology & Neonatology Authors: Geovanny F. Perez, Bassem Kurdi, Rosemary Megalaa, Krishna Pancham, Shehlanoor Huseni, Natalia Isaza, Carlos E. Rodriguez-Martinez, Dinesh Pillai, Gustavo Nino Tags: Original Article Source Type: research

Intrauterine inflammation, infection, or both (Triple I): A new concept for chorioamnionitis
Chorioamnionitis is a common cause of preterm birth and may cause adverse neonatal outcomes, including neurodevelopmental sequelae. Chorioamnionitis has been marked to a heterogeneous setting of conditions characterized by infection or inflammation or both, followed by a great variety in clinical practice for mothers and their newborns. Recently, a descriptive term: “intrauterine inflammation or infection or both” abbreviated as “Triple I” has been proposed by a National Institute of Child Health and Human Development expert panel to replace the term chorioamnionitis. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - October 20, 2017 Category: Perinatology & Neonatology Authors: Chun-Chih Peng, Jui-Hsing Chang, Hsiang-Yu Lin, Po-Jen Cheng, Bai-Horng Su Tags: Review Article Source Type: research

Altered regional and circuit resting-state activity in patients with occult spastic diplegic cerebral palsy
Very few studies have been made to investigate functional activity changes in occult spastic diplegic cerebral palsy (SDCP). The purpose of this study was to analyze whole-brain resting state regional brain activity and functional connectivity (FC) changes in patients with SDCP. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - October 20, 2017 Category: Perinatology & Neonatology Authors: Xuetao Mu, Zhiqun Wang, Binbin Nie, Shaofeng Duan, Qiaozhi Ma, Guanghui Dai, Chunnan Wu, Yuru Dong, Baoci Shan, Lin Ma Tags: Original Article Source Type: research

Intrauterine inflammation, infection, or both (Triple I): A new concept for chorioamnionitis
Chorioamnionitis is a common cause of preterm birth and may cause adverse neonatal outcomes, including neurodevelopmental sequelae. Chorioamnionitis has been marked to a heterogeneous setting of conditions characterized by infection or inflammation or both, followed by a great variety in clinical practice for mothers and their newborns. Recently, a descriptive term: “intrauterine inflammation or infection or both” abbreviated as “Triple I” has been proposed by a National Institute of Child Health and Human Development expert panel to replace the term chorioamnionitis. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - October 20, 2017 Category: Perinatology & Neonatology Authors: Chun-Chih Peng, Jui-Hsing Chang, Hsiang-Yu Lin, Po-Jen Cheng, Bai-Horng Su Tags: Review Article Source Type: research

Altered regional and circuit resting-state activity in patients with occult spastic diplegic cerebral palsy
Very few studies have been made to investigate functional activity changes in occult spastic diplegic cerebral palsy (SDCP). The purpose of this study was to analyze whole-brain resting state regional brain activity and functional connectivity (FC) changes in patients with SDCP. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - October 20, 2017 Category: Perinatology & Neonatology Authors: Xuetao Mu, Zhiqun Wang, Binbin Nie, Shaofeng Duan, Qiaozhi Ma, Guanghui Dai, Chunnan Wu, Yuru Dong, Baoci Shan, Lin Ma Tags: Original Article Source Type: research

Red blood cell transfusion in infants and children – Current perspectives
Children routinely receive packed red blood transfusion when they are admitted in the intensive care unit or undergoing cardiac surgeries. These guidelines aim to summarize literature and provide transfusion triggers exclusively in infants and children. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - October 18, 2017 Category: Perinatology & Neonatology Authors: Natasha Ali Tags: Review Article Source Type: research

Role of Zc3h12a in enhanced IL-6 production by newborn mononuclear cells in response to lipopolysaccharide
The uncontrolled inflammatory response following infection is closely related to the morbidity and mortality of neonates. Interleukin 6 (IL-6) plays an important role in the pathogenesis and prognosis of this process. To better elucidate the secretion of IL-6 following infection in neonates, we investigated the IL-6 level and mechanism of IL-6/TLR4 signaling pathways. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - October 18, 2017 Category: Perinatology & Neonatology Authors: Xia-Fang Chen, Jing Wu, Yi-Dan Zhang, Chen-Xing Zhang, Xu-Ting Chen, Jian-Hua Sun, Tong-Xin Chen Tags: Original Article Source Type: research

Red blood cell transfusion in infants and children – Current perspectives
Children routinely receive packed red blood transfusion when they are admitted in the intensive care unit or undergoing cardiac surgeries. These guidelines aim to summarize literature and provide transfusion triggers exclusively in infants and children. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - October 18, 2017 Category: Perinatology & Neonatology Authors: Natasha Ali Tags: Review Article Source Type: research

Role of Zc3h12a in enhanced IL-6 production by newborn mononuclear cells in response to lipopolysaccharide
The uncontrolled inflammatory response following infection is closely related to the morbidity and mortality of neonates. Interleukin 6 (IL-6) plays an important role in the pathogenesis and prognosis of this process. To better elucidate the secretion of IL-6 following infection in neonates, we investigated the IL-6 level and mechanism of IL-6/TLR4 signaling pathways. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - October 18, 2017 Category: Perinatology & Neonatology Authors: Xia-Fang Chen, Jing Wu, Yi-Dan Zhang, Chen-Xing Zhang, Xu-Ting Chen, Jian-Hua Sun, Tong-Xin Chen Tags: Original Article Source Type: research

Treatment outcomes and associated factors among extremely preterm infants in a major children hospital in Guangxi, China
In developing countries, infant survival rate and long-term outcomes of extremely preterm infants(EPIs) have significantly improved due to advances in perinatal care. The striking gap in the treatment outcome of EPIs between China and the other developed countries was a major concern. To assess treatment outcomes and associated factors among EPIs in Nanning, China. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - October 13, 2017 Category: Perinatology & Neonatology Authors: Yan Li, Qiu-fen Wei, Dan-hua Meng, Xin-nian Pan, Yan Mo, Li-ping Yao, Lian-fang Jing, Dan Zhao, Kai-yan Shen, Jing Xu Tags: Original Article Source Type: research

Sirenomelia with VACTERL association-a rare anomaly
Sirenomelia is a rare congenital disorder with complete or partial fusion of lower limbs. The incidence of Sirenomelia is reported to vary from 0.01 –0.16/10,000 live births with male to female ratio of 3:1.1 Risk factors include maternal gestational diabetes mellitus, tobacco use, and retinoic acid and heavy metal exposure. Sirenomelia is usually incompatible with life due to associated visceral anomalies. Here, we report a rare case of Siren omelia with multiple associated anomalies in the VACTERL spectrum which suggest a link in the pathogenesis between the two conditions. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - October 12, 2017 Category: Perinatology & Neonatology Authors: Vasanthan Tanigasalam, Mamatha Gowda, Nishad Plakkal, B. Adhisivam, B. Vishnu Bhat Tags: Short Communication Source Type: research

Neurodevelopmental outcomes at 3 years old for infants with birth weights under 500  g
Marked improvements have been achieved in the survival of extremely low birth weight infants, but survival rates and prognoses of extremely small infants with birth weights ≤500 g remain poor. The aim of this study was to clarify long-term outcomes for surviving infants with birth weights ≤500 g. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - October 12, 2017 Category: Perinatology & Neonatology Authors: Syunsuke Nagara, Masanori Kouwaki, Takao Togawa, Tokio Sugiura, Mayumi Okada, Norihisa Koyama Tags: Original Article Source Type: research

Sirenomelia with VACTERL association-a rare anomaly
Sirenomelia is a rare congenital disorder with complete or partial fusion of lower limbs. The incidence of Sirenomelia is reported to vary from 0.01 –0.16/10,000 live births with male to female ratio of 3:1.1 Risk factors include maternal gestational diabetes mellitus, tobacco use, and retinoic acid and heavy metal exposure. Sirenomelia is usually incompatible with life due to associated visceral anomalies. Here, we report a rare case of Siren omelia with multiple associated anomalies in the VACTERL spectrum which suggest a link in the pathogenesis between the two conditions. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - October 12, 2017 Category: Perinatology & Neonatology Authors: Vasanthan Tanigasalam, Mamatha Gowda, Nishad Plakkal, B. Adhisivam, B. Vishnu Bhat Tags: Short Communication Source Type: research

Neurodevelopmental outcomes at 3 years old for infants with birth weights under 500  g
Marked improvements have been achieved in the survival of extremely low birth weight infants, but survival rates and prognoses of extremely small infants with birth weights ≤500 g remain poor. The aim of this study was to clarify long-term outcomes for surviving infants with birth weights ≤500 g. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - October 12, 2017 Category: Perinatology & Neonatology Authors: Syunsuke Nagara, Masanori Kouwaki, Takao Togawa, Tokio Sugiura, Mayumi Okada, Norihisa Koyama Tags: Original Article Source Type: research

Trends in birth weight-specific and -adjusted infant mortality rates in Taiwan between 2004 and 2011
In this study, we examined the trends in birth weight-specific as well as birth weight-adjusted IMRs in Taiwan. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - September 28, 2017 Category: Perinatology & Neonatology Authors: Fu-Wen Liang, Hung-Chieh Chou, Shu-Ti Chiou, Li-Hua Chen, Mei-Hwan Wu, Hung-Chi Lue, Tung-Liang Chiang, Tsung-Hsueh Lu Tags: Original Article Source Type: research

Pulmonary artery hypertension in childhood: The transforming growth factor- β superfamily-related genes
Pulmonary artery hypertension (PAH) is very rare in childhood, and it can be divided into heritable, idiopathic drug- and toxin-induced and other disease (connective tissue disease, human immunodeficiency virus infection, portal hypertension, congenital heart disease, or schistosomiasis)-associated types. PAH could not be interpreted solely by pathophysiological theories. The impact of the transforming growth factor- β superfamily-related genes on the development of PAH in children remains to be clarified. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - September 26, 2017 Category: Perinatology & Neonatology Authors: Shi-Min Yuan Tags: Review Article Source Type: research

Age-related changes in biochemical bone profile in thalassemic children
This study was conducted with the objective to compare bone turnover mar kers (BTMs) in thalassemic children at different ages. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - September 26, 2017 Category: Perinatology & Neonatology Authors: Ehab S. Abd El-Moneim, Mohammed A. Zolaly, Zakaria M. Al-Hawsawi, Abeer A. Abdelmoneim, Mostafa M. Abosdera Tags: Original Article Source Type: research

Pulmonary artery hypertension in childhood: The transforming growth factor- β superfamily-related genes
Pulmonary artery hypertension (PAH) is very rare in childhood, and it can be divided into heritable, idiopathic drug- and toxin-induced and other disease (connective tissue disease, human immunodeficiency virus infection, portal hypertension, congenital heart disease, or schistosomiasis)-associated types. PAH could not be interpreted solely by pathophysiological theories. The impact of the transforming growth factor- β superfamily-related genes on the development of PAH in children remains to be clarified. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - September 26, 2017 Category: Perinatology & Neonatology Authors: Shi-Min Yuan Tags: Review Article Source Type: research

Age-related changes in biochemical bone profile in thalassemic children
This study was conducted with the objective to compare bone turnover mar kers (BTMs) in thalassemic children at different ages. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - September 26, 2017 Category: Perinatology & Neonatology Authors: Ehab S. Abd El-Moneim, Mohammed A. Zolaly, Zakaria M. Al-Hawsawi, Abeer A. Abdelmoneim, Mostafa M. Abosdera Tags: Original Article Source Type: research

No direct correlation between rotavirus diarrhea and breast feeding: A meta-analysis
In this study, we aimed to systematically find the associations between rotavirus diarrhea and breast feeding. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - September 25, 2017 Category: Perinatology & Neonatology Authors: Jian Shen, Bi-meng Zhang, Sheng-guo Zhu, Jian-jie Chen Tags: Original Article Source Type: research

A de novo 10.1-Mb 3p25 terminal deletion including SETD5 in a patient with ptosis and psychomotor retardation
Distal deletion of chromosome 3p25 (also termed as 3p-syndrome) was firstly reported in 1978.1 Since then, this rare disorder has been reported in approximately 50 patients, resulting from congenital distal end deletion of chromosome 3p. This syndrome is characterized by low birth weight, microcephaly, hypotonia, growth and psychomotor retardation, ptosis and/or blepharophimosis, congenital heart defects, and other features.2 In general, this chromosomal anomaly arises de novo, and breakpoints vary by cases. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - September 23, 2017 Category: Perinatology & Neonatology Authors: Hideaki Yagasaki, Takako Toda, Keiichi Koizumi, Takeshi Sugiyama, Tetsuo Ohyama, Minako Hoshiai, Takaya Nakane, Kanji Sugita Tags: Short Communication Source Type: research

A randomized pilot study comparing the role of PEEP, O2 flow, and high-flow air for weaning of ventilatory support in very low birth weight infants
This study sought to compare the efficacy of three weaning protocols we designed to facilitate weaning of very low birth weight (VLBW, less than 1500  g) preterm infants from nasal continuous positive airway pressure (NCPAP) support. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - September 21, 2017 Category: Perinatology & Neonatology Authors: Chang-Yo Yang, Mei-Chin Yang, Shih-Ming Chu, Ming-Chou Chiang, Reyin Lien Tags: Original Article Source Type: research

Pseudoureterocele
A 3-day-old female neonate was referred for antenatal hydronephrosis. Renal ultrasound revealed a left duplex collecting system with mild hydronephrosis and a tortuous hydroureter in the upper moiety. At the end of the hydroureter, a well-defined cystic structure with thickened and irregular wall was demonstrated inside the urinary bladder (Fig.  1; Video), and an intravesical ureterocele was suspected. However, no cystic mass was found when cystoscopy was performed. Magnetic resonance imaging (MRI) confirmed the diagnosis of a left duplex collecting system. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - September 20, 2017 Category: Perinatology & Neonatology Authors: Ming-Dar Lee, Chun-Chen Lin, Brian Pin-Hsuan Chang, Pei-Yi Lin, Jeng-Daw Tsai Tags: Pediatric Images Source Type: research

211 G to A variation of UGT1A1 and severe neonatal hyperbilirubinemia
We read with great interest the article by Yang et  al.1 that reported that UGT1A1 variation, Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency, and thalassemia may contribute to severe neonatal hyperbilirubinemia in southern China. Although this is an interesting and important finding that may have clinical implications, this study has some limi tations, and we would like to make some comments on this article. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - September 16, 2017 Category: Perinatology & Neonatology Authors: Yu-Jung Lin, Po-Nien Tsao Tags: Letter to the Editor Source Type: research

Predictors of outcome in neonatal hypoxic ischemic encephalopathy after therapeutic hypothermia
We read with great interest the article by Chiang et  al.1 that reported that higher serum levels of lactate (mg/dL) after 72 h of therapeutic hypothermia (TH) or abnormal brain magnetic resonance imaging (MRI) performed between 7 and 14 days of life were associated with poor neurodevelopmental outcome in neonatal hypoxic ischemic encephalopathy (HI E). Although this is an interesting and important finding that may have clinical implications, this study has some limitations, and we would like to make some comments on this article. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - September 14, 2017 Category: Perinatology & Neonatology Authors: Yu-Jung Lin, Po-Nien Tsao Tags: Letter to the Editor Source Type: research

Fighting against congenital hypothyroidism – Old soldiers never die
Congenital hypothyroidism (CH), the most common pediatric endocrine disorder, is also a preventable cause of mental retardation. Patients with a delayed diagnosis and treatment, present common symptoms and signs such as developmental delay, short stature, constipation, dry skin and periorbital edema. In addition, children with CH, have a higher risk of obesity due to adipose rebound at an earlier age. Chen et  al.1 recommended that it is necessary to supervise and control weight using appropriate interventions to prevent the occurrence of obesity at a later age. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - September 13, 2017 Category: Perinatology & Neonatology Authors: Shio-Jean Lin Tags: Editorial Source Type: research

Elevated urinary monocyte chemoattractant protein-1 levels in children with Henoch-Schonlein purpura nephritis
Chemokine monocyte chemoattractant protein-1 (MCP-1) has been proved as a potential urinary biomarker in nephropathies. The aim of this study was to investigate the urinary monocyte chemoattractant protein-1 (MCP-1) levels and clinical significance in Henoch-Schonlein purpura (HSP) children with and without nephritis and determine the association of MCP-1 with proteinuria. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - September 11, 2017 Category: Perinatology & Neonatology Authors: Jiapei Wang, Qianqian Ying, Shiling Zhong, Yuanling Chen, Yazhen Di, Xiahua Dai, Jika Zheng, Mengjiao Shen Tags: Original Article Source Type: research

The natural history of the patients with Duchenne muscular dystrophy in Taiwan: A medical center experience
Duchenne muscular dystrophy (DMD) is the most common hereditary muscular dystrophy and caused by DMD gene mutation. In addition to progressive proximal muscle weakness, respiratory, orthopedic, and gastrointestinal complications are often observed in DMD. The natural history of patients with DMD in Taiwan has not been reported thus far. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - September 11, 2017 Category: Perinatology & Neonatology Authors: Wen-Chen Liang, Chen-Hua Wang, Po-Ching Chou, Wan-Zi Chen, Yuh-Jyh Jong Tags: Original Article Source Type: research

Elevated urinary monocyte chemoattractant protein-1 levels in children with Henoch-Schonlein purpura nephritis
Chemokine monocyte chemoattractant protein-1 (MCP-1) has been proved as a potential urinary biomarker in nephropathies. The aim of this study was to investigate the urinary monocyte chemoattractant protein-1 (MCP-1) levels and clinical significance in Henoch-Schonlein purpura (HSP) children with and without nephritis and determine the association of MCP-1 with proteinuria. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - September 11, 2017 Category: Perinatology & Neonatology Authors: Jiapei Wang, Qianqian Ying, Shiling Zhong, Yuanling Chen, Yazhen Di, Xiahua Dai, Jika Zheng, Mengjiao Shen Tags: Original Article Source Type: research

The natural history of the patients with Duchenne muscular dystrophy in Taiwan: A medical center experience
Duchenne muscular dystrophy (DMD) is the most common hereditary muscular dystrophy and caused by DMD gene mutation. In addition to progressive proximal muscle weakness, respiratory, orthopedic, and gastrointestinal complications are often observed in DMD. The natural history of patients with DMD in Taiwan has not been reported thus far. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - September 11, 2017 Category: Perinatology & Neonatology Authors: Wen-Chen Liang, Chen-Hua Wang, Po-Ching Chou, Wan-Zi Chen, Yuh-Jyh Jong Tags: Original Article Source Type: research

Intussusception in a preterm newborn
Intussusception, the second most common abdominal emergency in childhood, is three times more common in men, and the peak age is before 2 years.1 –3 The incidence in neonates is 0.3–1.3 per 6000 cases.2–4 Till date, only 17 reports are available in PubMed and less than 50 cases in the English literature. Most of the cases were misdiagnosed as necrotizing enterocolitis (NEC), causing a delay in treatment. Herein, we present a case, demon strating how it is important that an early diagnosis in premature neonates with nonspecific symptoms affects the outcome. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - September 9, 2017 Category: Perinatology & Neonatology Authors: Emrah Aydin Tags: Short Communication Source Type: research

Beyond the inhaled nitric oxide in persistent pulmonary hypertension of the newborn
Persistent pulmonary hypertension (PPHN) is a consequence of failed pulmonary vascular transition at birth and leads to pulmonary hypertension with shunting of deoxygenated blood across the ductus arteriosus (DA) and foramen ovale (FO) resulting in severe hypoxemia, and it may eventually lead to life-threatening circulatory failure. PPHN is a serious event affecting both term and preterm infants in the neonatal intensive care unit. It is often associated with diseases such as congenital diaphragmatic hernia, meconium aspiration, sepsis, congenital pneumonia, birth asphyxia and respiratory distress syndrome. (Source: Pediat...
Source: Pediatrics and Neonatology - September 9, 2017 Category: Perinatology & Neonatology Authors: Mei-Yin Lai, Shih-Ming Chu, Satyan Lakshminrusimha, Hung-Chih Lin Tags: Review Article Source Type: research

Corrigendum to “Early erythropoietin administration does not increase the risk of retinopathy in preterm infants” [PEDN 58 (2017) 48–56]
This article titled “Early Erythropoietin Administration does not Increase the Risk of Retinopathy in Preterm Infants”, published in this journal, has a mistake. The grant number “DMR100-056” in the Acknowledgments should be corrected to “DMR101-040”. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - September 9, 2017 Category: Perinatology & Neonatology Authors: Hsin-Hsu Chou, Mei-Yung Chung, Xiao-Guang Zhou, Hung-Chih Lin Tags: Corrigendum Source Type: research

Effect of multiple neonatal sevoflurane exposures on hippocampal apolipoprotein E  levels and learning and memory abilities
In this study, we investigated whether early multiple exposures to sevoflurane induced cognitive dysfunction by altering the hippocampal expression of ApoE later in development. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - September 8, 2017 Category: Perinatology & Neonatology Authors: Junli Jiang, Chunchun Tang, Juanjuan Ren, Chao Zhang, Liang Dong, Zhaoqiong Zhu Tags: Original Article Source Type: research

Basilar-type migraine: An overlooked cause of loss of consciousness in pediatric emergency rooms
Basilar-type migraine (BTM) is a rare type of migraine characterized by brainstem aura such as vertigo, dysarthria, diplopia, and a decreased level of consciousness.1 The protean characteristic of BTM can confuse pediatricians in emergency rooms (ERs), particularly when patients present with a loss of consciousness (LOC) for the first time. Herein, we report the cases of two patients who were brought to the ER because of LOC. After a series of examinations, they ultimately received a diagnosis of BTM. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - September 7, 2017 Category: Perinatology & Neonatology Authors: I-Ching Chou, Inn-Chi Lee, Syuan-Yu Hong Tags: Short Communication Source Type: research

Nutritional support in preterm infants
We read with great interest the recent article on “Trend of Nutritional Support in Preterm Infants” reported by Ho MY et al.1 Both human and animal-based investigations indicate that insufficient protein intake during critical developmental periods may adversely affect long-term linear growth, neurodevelopmental outcomes, and general health. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - September 7, 2017 Category: Perinatology & Neonatology Authors: Ali Bulbul, Lida Bulbul, Sinan Uslu, Umut Zubarioglu Tags: Letter to the Editor Source Type: research

Respiratory syncytial virus associated hospitalizations in children with congenital diaphragmatic hernia
To evaluate the risk of RSV infection in infants and children with congenital diaphragmatic hernia (CDH) over two consecutive RSV seasons. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - September 5, 2017 Category: Perinatology & Neonatology Authors: Bernhard Resch, Krisztina Liziczai, Friedrich Reiterer, Thomas Freidl, Michaela Haim, Berndt Urlesberger Tags: Original Article Source Type: research

Cystic fibrosis complicated by cor pulmonale: The first case report in Taiwan
Cystic fibrosis (CF) is a common inherited disorder in the Caucasian population and characterized by defective chloride transport channel in epithelial cells. Lung disease majorly causes morbidity and mortality in CF patients. CF is rare among Asians, and (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - September 4, 2017 Category: Perinatology & Neonatology Authors: I-Hsuan Chen, Shyh-Dar Shyur, Yu-Chun Lin Tags: Short Communication Source Type: research