Neurodevelopmental outcomes of infants with very low birth weights are associated with the severity of their extra-uterine growth retardation
In this study, based on a single institute, we analyzed the association between different levels or severity of EUGR of VLBW infants and their neurodevelopmental outcomes later at a corrected age of 24 months. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - August 30, 2017 Category: Perinatology & Neonatology Authors: Han-Chun Chien, Chao-Huei Chen, Teh-Ming Wang, Ya-Chi Hsu, Ming-Chih Lin Tags: Original Article Source Type: research

Diagnostic value of conventional MRI combined with DTI for neonatal hyperbilirubinemia
Neonatal hyperbilirubinemia (NHB) is a common clinical disease and can cause bilirubin encephalopathy in severe cases. It is now widely accepted that increased signal intensity in the globus pallidus on MR T1WI is an important sign of neonatal bilirubin encephalopathy. And brain diffusion tensor imaging (DTI) has not been used extensively to study hyperbilirubinemia (HB). So we compared newborns with different hyperbilirubinemia of different severities and healthy newborns in order to determine the relationships among MRI signal intensities, serum bilirubin levels, and the molecular changes in brain water diffusion in hype...
Source: Pediatrics and Neonatology - August 29, 2017 Category: Perinatology & Neonatology Authors: Ruifang Yan, Dongming Han, Jipeng Ren, Zhansheng Zhai, Fengmei Zhou, Jingliang Cheng Tags: Original Article Source Type: research

Gamasoidosis (bird mite dermatitis): A case series in a family
An 18-month-old infant and a 12-year-old boy were assessed because of a two-days history of progressively pruritic lesions on the abdomen, chest, and back. On physical examination, multiple erythematous papules on the trunk and back were observed (Fig.  1). The patients' mother presented linear excoriations and lesions with corkscrew morphology on the upper limbs. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - August 23, 2017 Category: Perinatology & Neonatology Authors: Andreia de Oliveira Alves, Fred Bernardes Filho Tags: Pediatric Images Source Type: research

Successful treatment of a hepatic-hemangioendothelioma infant presenting with hypothyroidism and tetralogy of Fallot
Infantile hepatic hemangioendothelioma (IHHE), although rare, is one of the most common vascular tumors of the liver in children.1,2 Though the tumors are histologically benign, they occasionally cause life-threatening complications, such as cardiac failure, coagulation disorder, respiratory distress and, sometimes, hypothyroidism.1 Prednisolone was mainly used for treatment of symptomatic IHHE, but recently, several case reports showed the therapeutic effects of propranolol for IHHE.3 (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - August 22, 2017 Category: Perinatology & Neonatology Authors: Akari Takai, Tomoko Iehara, Mitsuru Miyachi, Yoshiki Okumura, Tatsuji Hasegawa, Sachiko Tokuda, Kazuyuki Ikeda, Masaaki Yamagishi, Tatsuro Tajiri, Hajime Hosoi Tags: Short Communication Source Type: research

The management and outcome of Bacillus Calmette –Guérin vaccine overdose
The Bacillus Calmette –Guérin (BCG) vaccine protects against disseminated tuberculosis (TB) and TB meningitis and is one of the most widely used vaccines worldwide. BCG has been included in the national immunization program in Taiwan since 1965.1 Since then, healthy neonates in Taiwan were immunized 24 h after birth with the Tokyo-172–based BCG vaccine until 2016, when the recommended BCG immunization timing was changed to 5–8 months of age. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - August 19, 2017 Category: Perinatology & Neonatology Authors: Sung-Hsi Wei, Wen-Chao Ho, Yi-Ting Chen, Shao-Hui Tsai Tags: Short Communication Source Type: research

Timing of sepsis is an important risk factor for white matter abnormality in extremely premature infants with sepsis
Systemic infection is a major upstream mechanism for white matter abnormality (WMA). Our aim was to evaluate the risk factors for moderate-to-severe WMA in extremely premature infants (gestational age   (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - August 18, 2017 Category: Perinatology & Neonatology Authors: Ju Sun Heo, Ee-Kyung Kim, Young Hun Choi, Seung Han Shin, Jin A Sohn, Jung-Eun Cheon, Han-Suk Kim Tags: Original Article Source Type: research

Hematopoietic stem cell transplantation for the treatment of leukocyte adhesion deficiency type III
We read with great interest the article published in Pediatrics and Neonatology by Aygun and colleagues.1 The authors described the cases of two children of Turkish origin who had leukocyte adhesion deficiency type III (LAD III). To date, fewer than 40 cases have been reported in the literature. In this article, the authors provided clinical data and conducted a biological investigation, including genetic analysis, that led to the diagnosis. They also provided interesting information regarding the treatment. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - August 18, 2017 Category: Perinatology & Neonatology Authors: Paul Saultier, Marie-Christine Alessi, G érard Michel, Hervé Chambost Tags: Letter to the Editor Source Type: research

Losartan in combination with propranolol slows the aortic root dilatation in neonatal Marfan syndrome
In this report, a combination of losartan and propranolol reduced the aortic root dilatation rate after three months of losartan therapy. Genetic analysis in this patient revealed a mutation in exon 25 of the FBN1 gene, which typically results in a shorter life expectancy. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - August 16, 2017 Category: Perinatology & Neonatology Authors: Lu-Hang Liu, Shan-Miao Lin, Dar-Shong Lin, Ming-Ren Chen Tags: Short Communication Source Type: research

A case of severe combined immunodeficiency caused by adenosine deaminase deficiency with a new mutation
Adenosine deaminase (ADA) deficiency is among the most common causes of severe combined immunodeficiency, characterized by dysfunction of the T, B, and natural killer (NK) cells (T-B-NK-SCID) and severe lymphopenia.1 ADA is a key enzyme in the purine salvage pathway, the absence of which causes lymph-toxic deoxyadenosine triphospate (dATP) accumulation, inhibiting ribonucleotide reductase, a critical enzyme for DNA replication and repair. This effect impairs the lymphocyte development and function resulting in severe combined immune deficiency (SCID). (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - August 16, 2017 Category: Perinatology & Neonatology Authors: Deniz Aygun, Ozden Turel, Murat Kardas, Emel Torun, Micheal Hershfield, Y ıldız Camcıoglu Tags: Brief Communication Source Type: research

An electronic smart watch monitors heart rate of an extremely preterm baby
The initial heart rate (HR) of a newborn after birth is at the core of initiation and evaluation of neonatal resuscitation.1 However, clinical assessment by auscultation of heart sound or palpation of the umbilical cord to obtain a HR reading was found to be both unreliable and inaccurate. The previous version of the neonatal resuscitation program (NRP) recommended that clinicians use pulse oximetry to evaluate the newborn's oxygenation and obtain an HR reading simultaneously. However, pulse oximetry takes a longer time and even fails to detect HR if tissue perfusion is insufficient. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - August 12, 2017 Category: Perinatology & Neonatology Authors: Yung-Chieh Lin, Kai-Che Wei Tags: Short Communication Source Type: research

Screening of congenital hypothyroidism in preterm, low birth weight and very low birth weight neonates: A systematic review
Evidence from different screening programs indicated that the rate of congenital hypothyroidism (CH) was higher in pre-term and low-birth-weight (LBW) newborns than normal ones. Incomplete development of hypothalamic –pituitary axis in this group of neonates results in the delayed rise of TSH and missing cases with CH. Hence, there is a great need for a practicable systematic screening method for proper diagnosis of CH in this group of neonates. In this review, we systematically reviewed papers with the follo wing key words ([Congenital Hypothyroidism AND Screening AND Thyroxine AND Thyroid Stimulating Hormone A...
Source: Pediatrics and Neonatology - August 12, 2017 Category: Perinatology & Neonatology Authors: Mahin Hashemipour, Silva Hovsepian, Arman Ansari, Mojtaba Keikha, Pooyan Khalighinejad, Negar Niknam Tags: Review Article Source Type: research

Congenital absence of ribs: A case report and review of the literature
Congenital absence of the ribs is relatively rare, and absence of the superior anterior ribs has not yet been documented.1,2 Herein, we report a full-term Chinese male infant born with the absence of the superior anterior 2nd –4th ribs on the left side without notable dyspnea. The diagnosis was made on three-dimensional computerized tomography (3D-CT) reconstruction imaging. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - August 10, 2017 Category: Perinatology & Neonatology Authors: Chengqiang Zhang, Jimei Wang Tags: Brief Communication Source Type: research

Multiple magnets trapped at the esophagogastric junction of a child
Magnet ingestion is an important issue. Ingestion of single magnets can be treated via clinical observation, monitoring the passage through the gastrointestinal tract, but multiple magnets should be extracted because of a high rate of serious complications such as fistulae, volvulus, or perforations.1 –3 (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - August 9, 2017 Category: Perinatology & Neonatology Authors: Hsun-Chin Chao, Chun-Hsiang Chang, Oi-Wa Chan Tags: Short Communication Source Type: research

Does the use of nasal continuous positive airway pressure increase the risk of a significant pneumothorax in late preterm and term infants?
Nasal continuous positive airway pressure (nCPAP) is widely used in neonatal units. It is often the preferred method of providing respiratory support in infants born at>30 weeks of gestation. With increasing cesarean sections, more near-term infants are admitted to neonatal units with respiratory symptoms. The threshold to intubate and ventilate varies among healthcare centers and nCPAP has been shown to be less harmful to newborn lungs compared with mechanical ventilation.1 Bukmaster et  al. reported that early use of nCPAP in infants born at>30 weeks of gestation reduced the need for transfer to the intensive ...
Source: Pediatrics and Neonatology - August 7, 2017 Category: Perinatology & Neonatology Authors: Rashmi Kuttysankaran, Naveen Athiraman, Alan C. Fenton, Sridhar M. Ramaiah Tags: Letter to the Editor Source Type: research

Association of preterm birth and small for gestational age with metabolic outcomes in  children and adolescents: A population-based cohort study from Taiwan
Previous studies have identified preterm birth and/or small for gestational age (SGA) as risk factors for features of the metabolic syndrome, including high blood pressure, insulin sensitivity and atherosclerosis, occurring later in life, with controversial results. We conducted this population-based cohort study to investigate metabolic outcomes in those with former preterm birth and/or SGA status in Taiwan. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - August 5, 2017 Category: Perinatology & Neonatology Authors: Yu-Ting Huang, Hsiang-Yu Lin, Chung-Hsing Wang, Bai-Horng Su, Che-Chen Lin Tags: Original Article Source Type: research

A 12-year-experience with tracheostomy for neonates and infants in northern Taiwan: Indications, hospital courses, and long-term outcomes
Tracheostomy is a valuable procedure in infants and neonates with chronic respiratory failure or severe airway obstruction. The aim of this study is to identify the indication, hospital course, and long-term outcome in a cohort of infants who required tracheostomy in a neonatal and pediatric tertiary care center in northern Taiwan. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - August 2, 2017 Category: Perinatology & Neonatology Authors: Chia-Huei Chen, Jui-Hsing Chang, Chyong-Hsin Hsu, Nan-Chang Chiu, Chun-Chin Peng, Wai-Tim Jim, Hung-Yang Chang, Kuo-Sheng Lee Tags: Original Article Source Type: research

Atropine use may lead to post-operative respiratory acidosis in neonates receiving ductal ligation: A retrospective cohort study
Patent ductus arteriosus (PDA) is one of the most common cardiac conditions in preterm infants. Closure of the PDA in symptomatic patients can be achieved medically or surgically. Atropine is commonly administered in general anesthesia as a premedication in this age group but with limited evidence addressing the effect of its use. Our study examined the association of the use of atropine as a premedication in PDA ligation and the risk of post-operative respiratory complications. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - August 2, 2017 Category: Perinatology & Neonatology Authors: Szu-Ling Chang, Wen-Li Lin, Chien-Hsiang Weng, Shye-Jao Wu, Hsin-Jung Tsai, Shwu-Meei Wang, Chun-Chih Peng, Jui-Hsing Chang Tags: Original Article Source Type: research

A 12-year-experience with tracheostomy for neonates and infants in northern Taiwan: Indications, hospital courses, and long-term outcomes
Tracheostomy is a valuable procedure in infants and neonates with chronic respiratory failure or severe airway obstruction. The aim of this study is to identify the indication, hospital course, and long-term outcome in a cohort of infants who required tracheostomy in a neonatal and pediatric tertiary care center in northern Taiwan. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - August 2, 2017 Category: Perinatology & Neonatology Authors: Chia-Huei Chen, Jui-Hsing Chang, Chyong-Hsin Hsu, Nan-Chang Chiu, Chun-Chin Peng, Wai-Tim Jim, Hung-Yang Chang, Kuo-Sheng Lee Tags: Original Article Source Type: research

Atropine use may lead to post-operative respiratory acidosis in neonates receiving ductal ligation: A retrospective cohort study
Patent ductus arteriosus (PDA) is one of the most common cardiac conditions in preterm infants. Closure of the PDA in symptomatic patients can be achieved medically or surgically. Atropine is commonly administered in general anesthesia as a premedication in this age group but with limited evidence addressing the effect of its use. Our study examined the association of the use of atropine as a premedication in PDA ligation and the risk of post-operative respiratory complications. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - August 2, 2017 Category: Perinatology & Neonatology Authors: Szu-Ling Chang, Wen-Li Lin, Chien-Hsiang Weng, Shye-Jao Wu, Hsin-Jung Tsai, Shwu-Meei Wang, Chun-Chih Peng, Jui-Hsing Chang Tags: Original Article Source Type: research

The impact of continuous renal replacement therapy for metabolic disorders in infants
While Continuous Renal Replacement Therapy (CRRT) is a well established treatment modality for patients with acute kidney insufficiency (AKI), it is now also being used for the management of various illnesses such as acute metabolic disorders presenting with hyperammonemia and elevated leucine levels. Herein, we aimed to describe our experience with CRRT in treatment of acute decompensation of 14 patients with a diagnosis of metabolic disorder who has been admitted to our pediatric intensive care unit (PICU) in the last year. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - August 1, 2017 Category: Perinatology & Neonatology Authors: Fatih Aygun, Deniz Aygun, Firuze Erbek Alp, Tanyel Zubar ıoglu, Cigdem Zeybek, Halit Cam Tags: Original Article Source Type: research

The analgesic effect of non-pharmacological interventions to reduce procedural pain in preterm neonates
Painful procedures are unavoidable in the medical care of preterm babies. The unpleasant experience during the neonatal period may contribute to hyperalgesia and poor neurodevelopment outcome later. Seeking effective interventions to reduce pain are strongly indicated for these very small premature babies. The aim of this study is to investigate if instilling breast milk (BM) or dextrose water into oral cavity can reduce the procedural pain of heel stick for preterm babies. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - July 21, 2017 Category: Perinatology & Neonatology Authors: Kao-Hsian Hsieh, Shu-Jen Chen, Pei-Chen Tsao, Chih-Chien Wang, Ching-Feng Huang, Chien-Ming Lin, Ya-Ling Chou, Wei-Yu Chen, I-Ching Chan Tags: Original Article Source Type: research

Neonatal solid tumors
Neonatal tumors are different from tumors of the older children and knowledge gained from treating older children can not be extrapolated to neonates. Neonates have immature physiology and their haematopoietic and immune systems are not fully developed and the response to therapy is unpredictable. Hence it is imperative to study these tumors as separate entity.The aim of this study is to analyse this rare set of tumors in terms of their incidence, clinical features and management. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - July 21, 2017 Category: Perinatology & Neonatology Authors: Aravindan Chandrasekaran Tags: Original Article Source Type: research

Influence of platelet count, platelet mass index, and platelet function on the spontaneous closure of ductus arteriosus in the prematurity
This study aims at evaluating the influence of platelet count, platelet mass index, and platelet function on the spontaneous closure of ductus arteriosus in prematurity. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - July 21, 2017 Category: Perinatology & Neonatology Authors: Dilek Kahvecioglu, Omer Erdeve, Hasan Akduman, Tayfun Ucar, Serdar Alan, Ufuk Çakır, Duran Yıldız, Begum Atasay, Saadet Arsan, Semra Atalay Tags: Original Article Source Type: research

Effect of bosentan therapy in persistent pulmonary hypertension of the newborn
Persistent pulmonary hypertension of the newborn (PPHN) contributes to neonatal hypoxemia and is associated with a high mortality. Some PPHN patients are unresponsive to inhaled nitric oxide (iNO). Bosentan, an oral endothelin-1 receptor antagonist, reduces pulmonary vascular resistance and hence may play a role in the treatment of PPHN. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - July 19, 2017 Category: Perinatology & Neonatology Authors: Gunlawadee Maneenil, Anucha Thatrimontrichai, Waricha Janjindamai, Supaporn Dissaneevate Tags: Original Article Source Type: research

The effects of reflexology on constipation and motor functions in children with cerebral palsy
This study was planned to investigate the effects of reflexology combined with neurodevelopmental therapy on constipation and motor functions in children with cerebral palsy. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - July 14, 2017 Category: Perinatology & Neonatology Authors: Bulent Elbasan, Sabiha Bezgin Tags: Original Article Source Type: research

The prevalence and characteristics of cow's milk protein allergy in infants and young children with iron deficiency anemia
The clinical presentation of cow's milk protein allergy (CMPA) in children varies. This retrospective study aimed to investigate the prevalence and clinical manifestations of CMPA in young children who visited for evaluation of iron deficiency anemia (IDA). (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - July 8, 2017 Category: Perinatology & Neonatology Authors: Fu-Ping Lai, Yao-Jong Yang Tags: Original Article Source Type: research

Iatrogenic aortic dissection in a preterm neonate presenting as acute renal failure
Acute aortic dissection is a life-threatening condition that is unusual in children and extremely rare in neonates.1 During childhood, aortic dissection is usually related to connective tissue disorders and congenital cardiovascular diseases, although iatrogenic cases have also been reported.2 –5 (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - July 8, 2017 Category: Perinatology & Neonatology Authors: Alejandro Avila-Alvarez, Victor Bautista-Hernandez, Fernando Rueda-Nu ñez Tags: Brief Communication Source Type: research

Pubertal timing, smoking, and sexual activity
Puberty is the transient period between childhood and adulthood during which reproductive function is attained. During this period, secondary sexual characteristics appear, adolescent growth spurt occurs, gonads start to produce mature gametes (sperms or oocytes) capable of fertilization, and major psychological changes occur.1 Puberty results from the activation of the complex neuroendocrine machinery whose primary mechanism is still unclear. Pubertal timing (PT) is influenced by complex interactions of genetic (family, ethnicity, and gender), nutritional, environmental (light –dark cycle and climatic conditions and...
Source: Pediatrics and Neonatology - June 20, 2017 Category: Perinatology & Neonatology Authors: Fu-Sung Lo Tags: Editorial Source Type: research

Clinical characteristics and epidemiology of sepsis in the neonatal intensive care unit in the era of multi-drug resistant organisms: A retrospective review
Sepsis in the neonatal intensive care unit (NICU) remains one of the most significant causes of morbidity and mortality, especially for preterm newborns. Multi-drug resistant organisms (MDROs) are emerging as important pathogens that cause neonatal sepsis in NICU. Therefore, studying the epidemiology, clinical features, and outcome caused by MDROs vs. non-MDROs, and identifying risk factors that may predispose patients to sepsis by MDROs are important. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - June 19, 2017 Category: Perinatology & Neonatology Authors: Dawood Yusef, Tala Shalakhti, Samah Awad, Hana'a Algharaibeh, Wasim Khasawneh Tags: Original Article Source Type: research

Flexible endoscopic diagnosis and treatment of esophageal stenosis in children with noninvasive ventilation support
Esophageal stenosis (ES) is characterized by dysphagia, failure to thrive, and long-term disability. It requires repeated management because it is refractory. Traditionally, these procedures are performed under general anesthesia with airway intubation. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - June 3, 2017 Category: Perinatology & Neonatology Authors: Kao-Hsian Hsieh, Wen-Jue Soong, Mei-Jy Jeng, Yu-Sheng Lee, Pei-Chen Tsao, Ya-Ling Chou Tags: Original Article Source Type: research

Successful resolution of Epstein –Barr virus-associated hemophagocytic lymphohistiocytosis during the treatment course of acute lymphoblastic leukemia
A primary infection of Epstein –Barr virus (EBV) in naïve B-cells is mostly asymptomatic, but occasionally causes infectious mononucleosis (IM). In contrast, the ectopic EBV infection in T-cells causes “systemic EBV-positive T-cell lymphoproliferative diseases (LPD) in childhood” including EBV-associated hemophagocytic lym phohistiocytosis (EBV-HLH) and a chronic active EBV infection.1 EBV-HLH rarely occurs in children during the treatment course of acute lymphoblastic leukemia (ALL). We hereby report a pediatric case of primary EBV infection-associated HLH during the induction treatment of precursor...
Source: Pediatrics and Neonatology - May 31, 2017 Category: Perinatology & Neonatology Authors: Mari Harada, Yuko Honda, Takayuki Hoshina, Shouichi Ohga, Koichi Ohshima, Koichi Kusuhara Tags: Brief Communication Source Type: research

Postnatal hyperoxia or DEHP exposure leads to growth restriction and delayed lung development in newborn rats
Di-(2-ethylhexyl) phthalate (DEHP) is commonly used as a plasticizer in many medical devices. We previously showed that maternal DEHP exposure led to restricted growth and delayed lung maturation in newborn rats. As oxygen toxicity continues to be a major risk factor for bronchopulmonary dysplasia, the aim of this study was to examine the effect of hyperoxia, DEHP or DEHP combined with hyperoxia on the growth and lung maturation of newborn rats. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - May 30, 2017 Category: Perinatology & Neonatology Authors: Zhong-Jie Liang, Qiu-Ping Wu, Bei-Tao Chen, Zhen-lang Lin, Jing Lin, Shang-Qin Chen Tags: Original Article Source Type: research

The sFlt-1/PlGF ratio as a predictor for poor pregnancy and neonatal outcomes
This study aimed to evaluate the association of sFlt-1/PlGF ratio with pregnancy outcomes, neonatal morbidities and short-term postnatal growth patterns in pregnant women and their babies. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - May 29, 2017 Category: Perinatology & Neonatology Authors: Yu-Shan Chang, Chi-Nien Chen, Suh-Fang Jeng, Yi-Ning Su, Chien-Yi Chen, Hung-Chieh Chou, Po-Nien Tsao, Wu-Shiun Hsieh Tags: Original Article Source Type: research

Parenting stress in parents of children with refractory epilepsy before and after vagus nerve stimulation implantation
The purpose of this study was to evaluate parenting stress in parents of children with refractory epilepsy before and after their children received vagus nerve stimulation (VNS) implantation. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - May 26, 2017 Category: Perinatology & Neonatology Authors: Sung-Tse Li, Nan-Chang Chiu, Yung-Ting Kuo, Ein-Yiao Shen, Pei-Chieh Tsai, Che-Sheng Ho, Wen-Hsiang Wu, Juei-Chao Chen, the VNS TCNS Tags: Original Article Source Type: research

A case of congenital Langerhans cell histiocytosis with disseminated skin and pulmonary involvement masquerading as multiple infantile hemangiomas
Langerhans cell histiocytosis (LCH) is a disorder characterized by abnormal proliferation of histiocytes, commonly involving the bone, skin, lungs, liver, spleen and lymph nodes. LCH is rare at birth and may easily be confused with other cutaneous lesions, thereby posing a diagnostic challenge for pediatricians. Herein, we present a patient with congenital LCH involving the skin and lungs who presented with multiple hemorrhagic vesicles with a large vascular mass at birth, closely resembling multiple infantile hemangiomas. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - May 25, 2017 Category: Perinatology & Neonatology Authors: Mindy Ming-Huey Guo, Chih-Cheng Chen, Feng-Shun Chen, Hsin-Chun Huang, Mei-Yung Chung, I-Lun Chen, Shang-Hung Lin, Mei-Chen Ou-Yang, Chih-Cheng Hsiao Tags: Brief Communication Source Type: research

Early provision of oropharyngeal colostrum leads to sustained breast milk feedings in preterm infants
The objectives of this study were to a) confirm the feasibility and safety of OC application in preterm infants and b) determine if OC application is associated with improved nutritional and clinical outcomes from birth to discharge. We hypothesized that OC application in the first few days would promote sustained breast milk feedings through discharge. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - May 24, 2017 Category: Perinatology & Neonatology Authors: Ruth Snyder, Aimee Herdt, Nancy Mejias-Cepeda, John Ladino, Kathryn Crowley, Philip Levy Tags: Original Article Source Type: research

Disappearance of globus pallidum lesions in T1-weighted magnetic resonance images after ligation of congenital portosystemic venous shunt
Congenital portosystemic venous shunt (CPSVS) is a rare vascular disorder in which the portal vein bypasses the liver and directly drains into the systemic vein. CPSVS has wide anatomical variations including patent ductus venosus. The complications of CPSVS include pulmonary hypertension, hepatic encephalopathy, and hepatic tumor.1 To prevent these complications, surgical ligation or catheter embolization of the shunt vessels, or liver transplantation is recommended.2 Symmetrical high signal in the basal ganglia on T1-weighted magnetic resonance images (MRI) of the brain indicating manganese accumulation is an important c...
Source: Pediatrics and Neonatology - May 23, 2017 Category: Perinatology & Neonatology Authors: Ryuichi Takemoto, Kenichiro Yamamura, Hazumu Nagata, Naoki Kawaguchi, Yasunari Sakai, Toshiharu Matsuura, Tomoaki Taguchi, Shouichi Ohga Tags: Pediatric Images Source Type: research

A customized iNO therapy device for use in neonatal emergency transport
The use of inhaled Nitric Oxide (iNO) to treat persistent pulmonary hypertension (PPH) in near-term and full-term neonates significantly improves oxygenation,1,2 and it is useful and safe.3,4 The “Equipment” section of the most recent edition of the “Guidelines for Air and Ground Transport of Neonatal and Pediatric Patients”5 clearly states the need to include iNO administration equipment among the specific recommendations for Neonatal-Pediatric Transport. The efficacy, safety, and u se of iNO during air and ground transport have been evaluated,6,7 and it was found that iNO can be safely delivered d...
Source: Pediatrics and Neonatology - May 22, 2017 Category: Perinatology & Neonatology Authors: Carlo Bellini, Luca A. Ramenghi Tags: Brief Communication Source Type: research

Liver exstrophy in a neonate with Poland syndrome
A female neonate was delivered by cesarean section at the 34th-week- of-gestation (wg) owing to a right extrathoracic mass, previously diagnosed at the 21st week. An MRI confirmed a herniated lump through a thoracic cleft. The amniotic fluid and karyotype were normal. The oval foramen and the arterial duct were patent. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - May 22, 2017 Category: Perinatology & Neonatology Authors: Xenophon Sinopidis, Antonios Panagidis, Vasileios Alexopoulos, Sotirios Tzifas, Gabriel Dimitriou, George Georgiou Tags: Pediatric Images Source Type: research

Respiratory severity score and extubation readiness in very low birth weight infants
The respiratory severity score (RSS) is a byproduct of mean airway pressure (MAP) and fraction of inspired oxygen (FiO2). We sought to determine whether RSS could be used as a screening tool to predict extubation readiness in very low birth weight (VLBW) infants. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - May 20, 2017 Category: Perinatology & Neonatology Authors: Maroun J. Mhanna, Narayan P. Iyer, Scott Piraino, Mohit Jain Tags: Original Article Source Type: research

Acute respiratory distress revealing massive pulmonary embolism in a neonate
A male neonate was delivered at 38 weeks of gestation. The pregnancy and delivery were uneventful. At 15 days of age, at home, he suddenly presented respiratory difficulties and cyanosis. At the arrival in the ICU, the baby was lethargic, had respiratory distress and generalized cyanosis. Oxygen saturation was 70% on 100% fraction of inspired O2 with facial mask ventilation. He required endotracheal intubation for respiratory support. Chest X-ray was unremarkable. Electrocardiogram revealed sinus tachycardia and right ventricular hypertrophy. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - May 19, 2017 Category: Perinatology & Neonatology Authors: Virginie Leriche, Angelina Dubois, Guy Vaksmann Tags: Pediatric Images Source Type: research