Bird’s Eye View of Neonatologist: Clinical Approach to Emergency Neonatal Infection
Publication date: Available online 23 October 2015 Source:Pediatrics & Neonatology Author(s): Fu-kuei Huang, Hsiu-Lin Chen, Peng-Hong Yang, Hung-Chih Lin Though the incidence of neonatal infection in term and near term infants is relatively low, incidence of infection in preterm very low birth weight (PVLBW) infants is as high as 20-30% and may result in neurodevelopmental impairment or mortality. Pediatricians should be familiar with recognition and emergency management of life-threatening neonatal infection such as congenital pneumonia, early onset sepsis; late onset sepsis, bacterial and fungal meningitis;...
Source: Pediatrics and Neonatology - November 9, 2015 Category: Perinatology & Neonatology Source Type: research

Urinary Transforming Growth Factor β-1 as a Marker of Renal Dysfunction in Sickle Cell Disease
Conclusion We concluded that urinary TGF-β1 may serve as a marker of early renal injury in SCD. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - November 9, 2015 Category: Perinatology & Neonatology Source Type: research

The Haplotype TGGAG in the ABCA3 Gene Increases the Risk of Respiratory Distress Syndrome in Preterm Infants in Southern China
Conclusion The TGGAG haplotype may be a risk factor for RDS in preterm infants in this Chinese population. Further study is needed with a larger sample size to verify the association between the rs17135889 SNP and increased risk of RDS in preterm infants, and to determine whether rs17135889 can be a reference in further population-based studies of ABCA3. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - November 9, 2015 Category: Perinatology & Neonatology Source Type: research

Restrictive Dermopathy
Publication date: Available online 28 October 2015 Source:Pediatrics & Neonatology Author(s): Atanu Kumar Dutta, Sumita Danda (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - November 9, 2015 Category: Perinatology & Neonatology Source Type: research

Endobronchial tuberculosis mimicking foreign body aspiration
Publication date: Available online 30 October 2015 Source:Pediatrics & Neonatology Author(s): Mehmet Nuri Cevizci, Soner Sertan Kara, Ali İhsan Dokucu (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - November 9, 2015 Category: Perinatology & Neonatology Source Type: research

Rotational Atherectomy and Stent Implantation in an 11-Year-Old Boy with a History of Kawasaki Disease
We describe the case of an 11-year-old boy who had experienced two episodes of Kawasaki disease with giant aneurysms at the ages of 8 and 11 months. Coronary angiography was performed at the age of 11 years because of frequent angina attacks. We found total occlusion of the right coronary artery, a giant aneurysm of the left main coronary artery, and substantial calcified stenosis of the left circumflex coronary artery (LCX, >70%). Balloon angioplasty failed to dilate the LCX lesion and caused intimal dissection and the no-flow phenomenon. Rotational atherectomy was thus performed together with stent implantation, w...
Source: Pediatrics and Neonatology - November 9, 2015 Category: Perinatology & Neonatology Source Type: research

Risk factors for intracardiac thrombosis in the right atrium and superior vena cava in critically ill neonates who required the installation of a central venous catheter
Conclusion: This study allowed us to identify several contributing factors to the development of intracardiac thrombosis in the right atrium and superior vena cava related to the installation of a CVC in a subgroup of critically ill neonates. Multicenter and well-designed studies with a larger number of patients could help validate our findings and/or identify other risk factors that were not identified in the present study. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - November 9, 2015 Category: Perinatology & Neonatology Source Type: research

Urinary Neutrophil Gelatinase-Associated Lipocalin Levels in Neonates
Acute kidney injury (AKI) is common in preterm infants and is associated with high mortality and morbidity. New biomarkers for the early detection of AKI have been identified. Specifically, urinary neutrophil gelatinase-associated lipocalin (uNGAL) is a new and powerful biomarker for AKI and sepsis. Our study evaluated the reference range of uNGAL in healthy neonates in Taiwan. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - November 9, 2015 Category: Perinatology & Neonatology Authors: Chi-Nien Chen, Chia-Hung Chou, Suh-Fang Jeng, I-Jung Tsai, Pau-Chung Chen, Chien-Yi Chen, Hung-Chieh Chou, Po-Nien Tsao, Wu-Shiun Hsieh Tags: Original article Source Type: research

A Simple and Rapid Test-card Method to Detect Hepatitis B Surface Antigen and Antibody: Potential Application in Young Children and Infants
Hepatitis B surface antigen (HBsAg) and hepatitis B surface antibody (anti-HBs) were conventionally determined by enzyme immunoassays. We aimed to apply a rapid, simple, and accurate method to detect HBsAg and its antibody. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - November 8, 2015 Category: Perinatology & Neonatology Authors: Fu-Yu Wu, Yu-Wun Liao, Jia-Feng Wu, Huey-Ling Chen, Hong-Yuan Hsu, Mei-Hwei Chang, Yen-Hsuan Ni Tags: Original article Source Type: research

Effects of Breast Milk and Vanilla Odors on Premature Neonate's Heart Rate and Blood Oxygen Saturation During and After Venipuncture
Different studies have shown that the use of olfactory stimuli during painful medical procedures reduces infants' response to pain. The main purpose of the current study was to investigate the effect of breast milk odor and vanilla odor on premature infants' vital signs including heart rate and blood oxygen saturation during and after venipuncture. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - November 8, 2015 Category: Perinatology & Neonatology Authors: Hanieh Neshat, Mahnaz Jebreili, Aleheh Seyyedrasouli, Morteza Ghojazade, Mohammad Bagher Hosseini, Hamed Hamishehkar Tags: Original article Source Type: research

A Simple and Rapid Test-card Method to Detect Hepatitis B Surface Antigen and Antibody: Potential Application in Young Children and Infants
Hepatitis B surface antigen (HBsAg) and hepatitis B surface antibody (anti-HBs) were conventionally determined by enzyme immunoassays. We aimed to apply a rapid, simple, and accurate method to detect HBsAg and its antibody. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - November 8, 2015 Category: Perinatology & Neonatology Authors: Fu-Yu Wu, Yu-Wun Liao, Jia-Feng Wu, Huey-Ling Chen, Hong-Yuan Hsu, Mei-Hwei Chang, Yen-Hsuan Ni Tags: Original article Source Type: research

Effects of Breast Milk and Vanilla Odors on Premature Neonate's Heart Rate and Blood Oxygen Saturation During and After Venipuncture
Different studies have shown that the use of olfactory stimuli during painful medical procedures reduces infants' response to pain. The main purpose of the current study was to investigate the effect of breast milk odor and vanilla odor on premature infants' vital signs including heart rate and blood oxygen saturation during and after venipuncture. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - November 8, 2015 Category: Perinatology & Neonatology Authors: Hanieh Neshat, Mahnaz Jebreili, Aleheh Seyyedrasouli, Morteza Ghojazade, Mohammad Bagher Hosseini, Hamed Hamishehkar Tags: Original article Source Type: research

Health Care for Adolescents in Taiwan: An Emerging Role of Pediatricians
The paper by Chuang et al1 is an interesting and important study looking at the pattern of health care-seeking behavior among patients younger than 18 years. The discussions around the crucial role of pediatricians in terms of competence and appropriateness in the medical services provided to sick children, including teenagers, are worthy of applause. The authors concluded an urgent need for advocacy of visits to pediatricians from the childhood up to age 18 years.1 (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - November 5, 2015 Category: Perinatology & Neonatology Authors: Meng-Che Tsai Tags: Letter to the Editor Source Type: research

Epidemiology of Hirschsprung's Disease in Taiwanese Children: A 13-year Nationwide Population-based Study
Hirschsprung's disease (HD) is an important colon disease in children. The aim of this study is to describe the epidemiological features of HD in Taiwanese children. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - November 2, 2015 Category: Perinatology & Neonatology Authors: Shu-Ti Chia, Solomon Chih-Cheng Chen, Chin-Li Lu, Shew-Meei Sheu, Hsing-Ching Kuo Tags: Original article Source Type: research

The Haplotype TGGAG in the ABCA3 Gene Increases the Risk of Respiratory Distress Syndrome in Preterm Infants in Southern China
This study evaluated whether common SNPs and consequent haplotypes increase susceptibility to RDS in a population of preterm infants from the Guangxi Zhuang Autonomous Region of China. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - October 27, 2015 Category: Perinatology & Neonatology Authors: Wenjun Tian, Xiuqi Chen, Huijuan Qin, Qiufen Wei, Shuying Zhang, Shangying Tang, Liangrong Liao, Yanming Zhang, Yujun Chen Tags: Original article Source Type: research

Childhood Atopic Dermatitis in Taiwan
The prevalence of atopic dermatitis (AD) appears to have increased dramatically over the past decades. It is generally believed that such rapid increase in prevalence cannot be explained fully by genetic factors. Environmental factors might play a role in such an increment. Children with AD are most likely to suffer considerable school absences, family stress, and health care expenditures. Because the onset of AD occurs relatively early in life, identification of early life risk factors and early management for AD to prevent the development of atopic march are of critical importance. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - October 27, 2015 Category: Perinatology & Neonatology Authors: I-Jen Wang, Jiu-Yao Wang, Kuo-Wei Yeh Tags: Review article Source Type: research

Can Macrosomia or Large for Gestational Age Be Predictive of Mucopolysaccharidosis Type I, II and VI?
The objective of the study was to compare mean values for birth body length and weight between patients with mucopolysaccharidosis (MPS) and the general population. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - October 27, 2015 Category: Perinatology & Neonatology Authors: Agnieszka Różdżyńska-Świątkowska, Agnieszka Jurecka, Zbigniew Żuber, Anna Tylki-Szymańska Tags: Original article Source Type: research

The Haplotype TGGAG in the Gene Increases the Risk of Respiratory Distress Syndrome in Preterm Infants in Southern China
This study evaluated whether common SNPs and consequent haplotypes increase susceptibility to RDS in a population of preterm infants from the Guangxi Zhuang Autonomous Region of China. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - October 27, 2015 Category: Perinatology & Neonatology Authors: Wenjun Tian, Xiuqi Chen, Huijuan Qin, Qiufen Wei, Shuying Zhang, Shangying Tang, Liangrong Liao, Yanming Zhang, Yujun Chen Tags: Original article Source Type: research

Can Macrosomia or Large for Gestational Age Be Predictive of Mucopolysaccharidosis Type I, II and VI?
The objective of the study was to compare mean values for birth body length and weight between patients with mucopolysaccharidosis (MPS) and the general population. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - October 27, 2015 Category: Perinatology & Neonatology Authors: Agnieszka R óżdżyńska-Świątkowska, Agnieszka Jurecka, Zbigniew Żuber, Anna Tylki-Szymańska Tags: Original article Source Type: research

The Haplotype TGGAG in the ABCA3 Gene Increases the Risk of Respiratory Distress Syndrome in Preterm Infants in Southern China
This study evaluated whether common SNPs and consequent haplotypes increase susceptibility to RDS in a population of preterm infants from the Guangxi Zhuang Autonomous Region of China. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - October 27, 2015 Category: Perinatology & Neonatology Authors: Wenjun Tian, Xiuqi Chen, Huijuan Qin, Qiufen Wei, Shuying Zhang, Shangying Tang, Liangrong Liao, Yanming Zhang, Yujun Chen Tags: Original article Source Type: research

Urinary Transforming Growth Factor β-1 as a Marker of Renal Dysfunction in Sickle Cell Disease
Sickle cell disease (SCD) is a genetic disorder that results in deformity of red blood cells. Renal dysfunction affects 5–18% of patients with SCD. To date, few studies have described urinary levels of transforming growth factor β-1 (TGF-β1), which is a marker of fibrosis, as a biomarker in identifying patients at risk of developing renal disease in SCD. The aim of this study is to determine prevalence of sickle cell nephropathy in Egyptian SCD patients. We aimed also to evaluate the association of urinary TGF-β1 with other conventional biomarkers of renal damage in SCD patients to identify a novel ren...
Source: Pediatrics and Neonatology - October 24, 2015 Category: Perinatology & Neonatology Authors: Emad E. Ghobrial, Hanan A. Abdel-Aziz, Ahmed M. Kaddah, Nesma A. Mubarak Tags: Original article Source Type: research

Urinary Transforming Growth Factor β-1 as a Marker of Renal Dysfunction in Sickle Cell Disease
Sickle cell disease (SCD) is a genetic disorder that results in deformity of red blood cells. Renal dysfunction affects 5 –18% of patients with SCD. To date, few studies have described urinary levels of transforming growth factor β-1 (TGF-β1), which is a marker of fibrosis, as a biomarker in identifying patients at risk of developing renal disease in SCD. The aim of this study is to determine prevalence of sickle c ell nephropathy in Egyptian SCD patients. We aimed also to evaluate the association of urinary TGF-β1 with other conventional biomarkers of renal damage in SCD patients to identify a novel r...
Source: Pediatrics and Neonatology - October 24, 2015 Category: Perinatology & Neonatology Authors: Emad E. Ghobrial, Hanan A. Abdel-Aziz, Ahmed M. Kaddah, Nesma A. Mubarak Tags: Original article Source Type: research

Transitional Hemodynamics in Preterm Neonates: Clinical Relevance
Each newborn enters this world facing tremendous respiratory, hemodynamic and neuroendocrine challenges while going through drastic physiological changes during the process of adaption from fetal to postnatal life. Even though the vast majority of term infants transition smoothly without apparent consequences, this task becomes increasingly arduous for the extremely preterm infant. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - October 16, 2015 Category: Perinatology & Neonatology Authors: Tai-Wei Wu, Timur Azhibekov, Istvan Seri Tags: Invited review article Source Type: research

Duration of Hospitalization in Association with Type of Inhalation Therapy Used in the Management of Children with Nonsevere, Acute Bronchiolitis
Acute bronchiolitis is one of the main respiratory emergencies in young children. Although supportive therapy is recommended, substantial inconsistency in the clinical usage of inhaled treatments has been reported. In the present study, we evaluated the association between different types of nebulized therapies in clinical practice and the length of stay (LOS) of young children hospitalized with nonsevere bronchiolitis. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - October 10, 2015 Category: Perinatology & Neonatology Authors: Jamie M. Pinto, Janet L. Schairer, Anna Petrova Tags: Original article Source Type: research

Gabapentin for Postoperative Vomiting in Children Requiring Posterior Fossa Tumor Resection
This report suggests that gabapentin may be a novel antiemetic therapeutic intervention for patients with refractory nausea and vomiting after craniotomy. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - October 9, 2015 Category: Perinatology & Neonatology Source Type: research

Successful Unrelated Cord Blood Stem Cell Transplantation in an X-linked Chronic Granulomatous Disease Patient with Disseminated BCG-induced Infection
Publication date: October 2015 Source:Pediatrics & Neonatology, Volume 56, Issue 5 Author(s): Chao-Jen Lin, Shih-Chung Wang, Cheng-Lung Ku, Jun-kai Kao, Ming Chen, Chin-San Liu A 19-month-old boy with chronic granulomatous disease (CGD) received umbilical cord blood transplantation (UCBT) from an unrelated donor after experiencing a life-threatening disseminated Bacillus Calmette–Guérin infection. After busulfan and cyclophosphamide conditioning, we performed a 5/6-matched UCBT. Engraftment and mixed chimerism was 100% in peripheral blood, and 100% of his neutrophils had normal oxidative burst ...
Source: Pediatrics and Neonatology - October 9, 2015 Category: Perinatology & Neonatology Source Type: research

Urinary Neutrophil Gelatinase-Associated Lipocalin Levels in Neonates
Conclusion This study presents preliminary data on uNGAL levels for neonates in Taiwan. A large-scale study investigating the correlations between uNGAL and GA, BBW, gender, and PNA is recommended. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - October 9, 2015 Category: Perinatology & Neonatology Source Type: research

Decreased CysC-eGFR correlates with prolonged hospital stay in TTN infants.
Conclusions Tachypnea duration was shorter with higher Cys C-based eGFR in TTN infants. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - October 4, 2015 Category: Perinatology & Neonatology Source Type: research

Can macrosomia or large for gestational age be predictive of mucopolysaccharidosis?
Conclusion At the time of birth, MPS patients were larger than those in general population. High birth weight and/or LGA can be suggestive of MPS disease and should raise suspicion aiding in early disease recognition. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - October 2, 2015 Category: Perinatology & Neonatology Source Type: research

An Extended Way to Predict Neonatal Hypoxic Ischemic Encephalopathy
Publication date: Available online 3 September 2015 Source:Pediatrics & Neonatology Author(s): Shyi-Jou Chen (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - September 26, 2015 Category: Perinatology & Neonatology Source Type: research

Childhood Atopic Dermatitis in Taiwan
Publication date: Available online 25 September 2015 Source:Pediatrics & Neonatology Author(s): I-Jen Wang, Jiu-Yao Wang, Kuo-Wei Yeh The prevalence of atopic dermatitis (AD) appears to have increased dramatically over the past decades. It is generally believed that such rapid increase in prevalence cannot be explained fully by genetic factors. Environmental factors might play a role in such an increment. Children with AD are most likely to suffer considerable school absences, family stress, and health care expenditures. Since the onsets of AD are relatively early in life, identification of early life risk fac...
Source: Pediatrics and Neonatology - September 25, 2015 Category: Perinatology & Neonatology Source Type: research

A Clinical Study of the N-Terminal pro-Brain Natriuretic Peptide in Myocardial Injury after Neonatal Asphyxia
Conclusion The serum NT-proBNP level can reflect myocardial injury in neonates with asphyxia and can guide its diagnosis. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - September 16, 2015 Category: Perinatology & Neonatology Source Type: research

A Clinical Study of the N-Terminal pro-Brain Natriuretic Peptide in Myocardial Injury after Neonatal Asphyxia
We aimed to study the changes of serum N-terminal pro-brain natriuretic to peptide (NT-proBNP) levels after asphyxia-induced myocardial injury in children and explore the relationship between serum NT-proBNP levels and neonatal asphyxia. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - September 15, 2015 Category: Perinatology & Neonatology Authors: Rui Zhu, Zhenhong Nie Tags: Original article Source Type: research

Duration of hospitalization in association with type of inhalation therapy used in the management of children with non-severe, acute bronchiolitis
Conclusions Prolonged hospitalization of children under two years of age with acute, non-severe bronchiolitis is associated with administration of nebulized 3% saline independent of age, clinical presentation of disease or inclusion of other treatments in their management. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - September 15, 2015 Category: Perinatology & Neonatology Source Type: research

Angiogenic Factors in Bronchopulmonary Dysplasia
Publication date: Available online 11 September 2015 Source:Pediatrics & Neonatology Author(s): Hsin-Chun Huang (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - September 13, 2015 Category: Perinatology & Neonatology Source Type: research

Identification and Characterization of Mutations in the CLCN7 Gene in a Taiwanese Patient with Infantile Malignant Osteopetrosis
Osteopetrosis is a rare bone disease characterized by an abnormal increase in bone density and a decrease in bone mechanical strength, and comprises a heterogeneous group of disorders.1 Autosomal recessive osteopetrosis (ARO) is the most severe form of osteopetrosis, with the most severe symptom being the lack of bone marrow. An abnormal inward expansion of bone cortex interferes with normal medullary hematopoiesis and causes life-threatening pancytopenia and infection.1 (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - September 10, 2015 Category: Perinatology & Neonatology Authors: Wei-De Lin, Chung-Hsing Wang, Kang-His Wu, I-Ching Chou, Fuu-Jen Tsai Tags: Brief communication Source Type: research

Identification and Characterization of Mutations in the Gene in a Taiwanese Patient with Infantile Malignant Osteopetrosis
Osteopetrosis is a rare bone disease characterized by an abnormal increase in bone density and a decrease in bone mechanical strength, and comprises a heterogeneous group of disorders.1 Autosomal recessive osteopetrosis (ARO) is the most severe form of osteopetrosis, with the most severe symptom being the lack of bone marrow. An abnormal inward expansion of bone cortex interferes with normal medullary hematopoiesis and causes life-threatening pancytopenia and infection.1 (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - September 10, 2015 Category: Perinatology & Neonatology Authors: Wei-De Lin, Chung-Hsing Wang, Kang-His Wu, I-Ching Chou, Fuu-Jen Tsai Tags: Brief communication Source Type: research

An Extended Way for Prediction of Neonatal Hyopoxic Ischemic Encephalopathy
Publication date: Available online 3 September 2015 Source:Pediatrics & Neonatology Author(s): Shyi-Jou Chen (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - September 4, 2015 Category: Perinatology & Neonatology Source Type: research

Transitional hemodynamics in preterm neonates: Clinical Relevance
Publication date: Available online 29 August 2015 Source:Pediatrics & Neonatology Author(s): Tai-Wei Wu, Timur Azhibekov, Istvan Seri (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - August 30, 2015 Category: Perinatology & Neonatology Source Type: research

Origins of Adolescent Obesity and Hypertension
Publication date: Available online 29 August 2015 Source:Pediatrics & Neonatology Author(s): Chun-Hsien Yu (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - August 29, 2015 Category: Perinatology & Neonatology Source Type: research

Effects of Maternal Stress During Pregnancy on Birth Outcome and Stress-related Hormones
Publication date: Available online 29 August 2015 Source:Pediatrics & Neonatology Author(s): Ming-Chou Chiang (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - August 29, 2015 Category: Perinatology & Neonatology Source Type: research

Prenatal Therapy Improves the Survival of Premature Infants with Congenital Chylothorax
Chylothorax is a rare condition among neonates, although it is considered clinically significant, as it is difficult to manage in these patients. In addition, the course of chylothorax varies widely. Therefore, we aimed to elucidate the clinical features and effect of prenatal therapy on the prognosis of congenital chylothorax in neonates. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - August 24, 2015 Category: Perinatology & Neonatology Authors: Chia-Jung Lee, Po-Nien Tsao, Chien-Yi Chen, Wu-Shiun Hsieh, Jyun-you Liou, Hung-Chieh Chou Tags: Original article Source Type: research

Dramatic Improvement in Juvenile Parkinsonism after Levodopa Treatment in a Patient Negative for the PANK2 Mutation
Publication date: Available online 3 July 2015 Source:Pediatrics & Neonatology Author(s): Syuan-Yu Hong, Inn-Chi Lee (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - August 21, 2015 Category: Perinatology & Neonatology Source Type: research

A clinical study of the N-terminal brain natriuretic peptide in myocardial injury after neonatal asphyxia
Conclusion The serum NT-proBNP level can reflect myocardial injury in neonates with asphyxia and can guide its diagnosis. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - August 21, 2015 Category: Perinatology & Neonatology Source Type: research

Dramatic Improvement in Juvenile Parkinsonism after Levodopa Treatment in a Patient Negative for the Mutation
Juvenile parkinsonism is a rare movement disorder. In pediatric patients, the manifestations are more complex and varied, which makes the diagnosis challenging. It may occasionally manifest as another disease such as dopa-responsive dystonia, Wilson disease, or neurodegeneration with brain iron accumulation (i.e., Hallervorden–Spatz disease).1,2 This paper reports a 14-year-old girl who experienced a variety of movement disorders such as parkinsonism and dystonia. Her symptoms changed and worsened within a few years, but dramatically improved with levodopa treatment. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - August 19, 2015 Category: Perinatology & Neonatology Authors: Syuan-Yu Hong, Inn-Chi Lee Tags: Brief communication Source Type: research

Retinol and Alpha-tocopherol in the Colostrum of Lactating Tunisian Women Delivering Prematurely: Associations with Maternal Characteristics
This study aims to assess vitamin A and E concentrations in the premature colostrum of lactating Tunisian women and to identify maternal characteristics that may affect these concentrations. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - August 17, 2015 Category: Perinatology & Neonatology Authors: Samira Fares, Mohamed Marouane Sethom, Samia Kacem, Imen Ksibi, Moncef Feki, Sami Jebnoun, Naziha Kaabachi Tags: Original article Source Type: research

Identification and Characterization of Mutations in the CLCN7 Gene in A Taiwanese Patient with Infantile Malignant Osteopetrosis
This study extended the spectrum of CLCN7 mutations and revealed that the p.Arg286Gln mutation, combined with a deletion mutation, caused a severe type of ARO. In addition, CLCN7 gene profiling may be useful in genetic counseling for families affected by ARO. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - August 15, 2015 Category: Perinatology & Neonatology Source Type: research

Prenatal Therapy Improves the Survival of Premature Infants with Congenital Chylothorax
Conclusion We found that infants whose chylothorax was diagnosed ≤ 34 weeks of gestation, and who subsequently received prenatal therapy, experienced better perinatal condition and exhibited improved postnatal outcomes. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - July 31, 2015 Category: Perinatology & Neonatology Source Type: research

A Newborn with Congenital Mixed Phenotype Acute Leukemia After In Vitro Fertilization
Publication date: August 2015 Source:Pediatrics & Neonatology, Volume 56, Issue 4 Author(s): Hacer Ergin, Özmert M.A. Özdemir, Abdullah Karaca, Nilay Şen Türk, Füsun Düzcan, Şeniz Ergin, Elif Kazancı, Canan Vergin, Ayşe Erbay Congenital leukemia is a rare disease. The majority of cases of this disease are acute myelogenous leukemia (AML). Congenital acute lymphoblastic leukemia (ALL) is rare and most often is of B cell lineage. Rarely, some cases have been designated biphenotypic or mixed phenotype acute leukemia (MPAL). Herein, we report a preterm newborn referred to us as a...
Source: Pediatrics and Neonatology - July 31, 2015 Category: Perinatology & Neonatology Source Type: research