RNA-seq analysis for exploring the pathogenesis of Retinitis pigmentosa in P23H knock-in mice
(Source: Ophthalmic Research)
Source: Ophthalmic Research - May 11, 2021 Category: Opthalmology Source Type: research

Fourier-Transform Infrared Spectroscopy of Epiretinal Membranes and Internal Limiting Membranes after Pars Plana Vitrectomy with Membrane Peeling
(Source: Ophthalmic Research)
Source: Ophthalmic Research - May 4, 2021 Category: Opthalmology Source Type: research

Retinal vessel phenotype in patients with a history of retinal vein occlusion
(Source: Ophthalmic Research)
Source: Ophthalmic Research - April 27, 2021 Category: Opthalmology Source Type: research

In vivo noninvasive imaging and quantitative analysis of iris vessels
(Source: Ophthalmic Research)
Source: Ophthalmic Research - April 21, 2021 Category: Opthalmology Source Type: research

Effects of single and repeated intravitreal applications of atropine on choroidal thickness in alert chickens
(Source: Ophthalmic Research)
Source: Ophthalmic Research - March 25, 2021 Category: Opthalmology Source Type: research

Descemet membrane endothelial keratoplasty and Bowman layer transplantation: an anatomic review and historical survey
(Source: Ophthalmic Research)
Source: Ophthalmic Research - March 23, 2021 Category: Opthalmology Source Type: research

Optical Coherence Tomography Biomarkers: Vitreous Status Influence in Outcomes for Diabetic Macular Edema Therapy with 0.19-mg Fluocinolone Acetonide Implant
Conclusions: This study supports the effectiveness of the FAc implant and reports significant changes at 12 months after FAc injection. (Source: Ophthalmic Research)
Source: Ophthalmic Research - March 16, 2021 Category: Opthalmology Source Type: research

Current management of patients with RPE65 mutation-associated inherited retinal degenerations (IRDs) in Europe. Results of a multinational survey by the European Vision Institute Clinical Research Network EVICR.net
(Source: Ophthalmic Research)
Source: Ophthalmic Research - March 7, 2021 Category: Opthalmology Source Type: research

Alternative Flicker Glass: a New Anti-suppression Approach to the Treatment of Anisometropic Amblyopia
Conclusion: Alternative flicker glass was effective in improving both monocular and binocular function, which was most likely achieved by reducing the suppre ssion and promoting binocular fusion. This therapy exhibited promise as an alternative method for amblyopia treatment. (Source: Ophthalmic Research)
Source: Ophthalmic Research - March 1, 2021 Category: Opthalmology Source Type: research

Optical Coherence Tomography Biomarkers - Vitreous Status Influence in Outcomes for Diabetic Macular Edema Therapy with 0.19 mg Fluocinolone Acetonide Implant
Conclusions: This study supports the effectiveness of the FAc implant and reports significant changes at 12 months post-FAc injection. (Source: Ophthalmic Research)
Source: Ophthalmic Research - February 17, 2021 Category: Opthalmology Source Type: research

Inverted internal limiting membrane flap technique versus internal limiting membrane peeling for large macular holes: A meta-analysis of randomized controlled trials
Conclusions: Vitrectomy with inverted ILM flap technique showed a higher anatomical closure rate as well as visual gain —although only in the short-term as no difference in visual recovery was found at the 6-month follow-up—than did ILM peeling in large MHs. The inverted ILM flap technique should be considered as a preferred and routine procedure for the treatment of patients with MHs larger than 400 µm. (Source: Ophthalmic Research)
Source: Ophthalmic Research - February 16, 2021 Category: Opthalmology Source Type: research

Thyroid disease is associated with higher age-related macular degeneration risk: results from a meta-analysis of epidemiologic studies
Conclusions: Our findings indicate that thyroid disease is associated with higher AMD risk. Thyroid disease prevention strategies may have a significant effect on the p revention of AMD and warrant further evaluation. (Source: Ophthalmic Research)
Source: Ophthalmic Research - February 16, 2021 Category: Opthalmology Source Type: research

Evaluation of axial length measurement using enhanced retina visualization mode of the swept-source optical coherence tomography biometer in dense cataract
Conclusion: In patients with dense cataracts , AL measurement using the standard mode of an SS-OCT biometer is challenging. Furthermore, the ERV mode could be promising for AL measurement in such cases. (Source: Ophthalmic Research)
Source: Ophthalmic Research - February 4, 2021 Category: Opthalmology Source Type: research

Protective Effect of a bi-specific Fc-fusion protein on the barrier of hRPE cells
To evaluate the protective effects of IBI302, a bi-specific Fc-fusion protein that theoretically can bind vascular endothelial growth factor (VEGF), complement C3b and C4b in the cultured human retinal pigment epithelial (hRPE) cells. Primary hRPE cells were isolated and cultured to monolayer barrier. hRPE monolayers were divided into control group, VEGF-Trap group, complement receptor 1 (CR1) group, and IBI302 group. Identification of hRPE cells, barrier function, inflammation factors and immune response products were tested by immunofluorescent staining, transepithelial resistance (TER) and ELISA. IBI302 treatment signif...
Source: Ophthalmic Research - February 4, 2021 Category: Opthalmology Source Type: research

Ultrasound cycloplasty in Chinese glaucoma patients: Results of a 6-month prospective clinical study
Conclusion: UCP p rocedure is an effective and well-tolerated treatment to reduce IOP in Chinese glaucoma patients, which offered a novel alternative for glaucoma treatment. (Source: Ophthalmic Research)
Source: Ophthalmic Research - February 3, 2021 Category: Opthalmology Source Type: research