SD-OCT analysis in syndromic and non-syndromic forms of retinitis pigmentosa due to USH2A gene mutations
This study aims to analyze macular structure by using SD-OCT in a cohort of patients affected by autosomal recessive retinitis pigmentosa and Usher syndrome, due to genetic variants in USH2A gene, and to correlate OCT parameters with functional and genetic data.
Methods: The subjects of this study were 92 patients, 46 syndromic (Ush2) and 46 non-syndromic (arRP), with clinical and genetic diagnosis of USH2A-related retinal dystrophy, who underwent a complete ophthalmic examination and spectral domain OCT analysis. The study focused on evaluating the differences between the two groups in the following parameters: best corr...
Source: Ophthalmic Research - November 15, 2021 Category: Opthalmology Source Type: research
Structural abnormalities of the central retina in Neurofibromatosis type 2
(Source: Ophthalmic Research)
Source: Ophthalmic Research - October 21, 2021 Category: Opthalmology Source Type: research
Research Progress on Morphological Changes and Surgery-Related Parameters of Corneal Cap in Small-Incision Lenticule Extraction
Small-incision lenticule extraction (SMILE) is an “all-in-one” surgical method for refractive correction. An advantage of the SMILE over traditional surgery is that it depends on the corneal cap’s design. This review discusses the morphological evaluation of the corneal cap, selection of the corneal cap with different thicknesses and diameter s, influence of the corneal cap design on re-treatment, and management of corneal cap-related complications. The following points should be recognized to define the correct morphology and design of the operation-related parameters of the corneal cap during SMILE: (1) the thickne...
Source: Ophthalmic Research - October 20, 2021 Category: Opthalmology Source Type: research
Research Progress on Morphological Changes and Surgery-related Parameters of Corneal Cap in Small Incision Lenticule Extraction
Small incision lenticule extraction (SMILE) is an "all-in-one" surgical method for refractive correction. An advantage of the SMILE over traditional surgery is that it depends on the corneal cap ’s design. This review discusses the morphological evaluation of the corneal cap, selection of the corneal cap with different thickness and diameters, influence of the corneal cap design on retreatment, and management of corneal cap-related complications. The following points should be recognized to define the correct morphology and design of the operation-related parameters of the corneal cap during SMILE: (1) the thickness and ...
Source: Ophthalmic Research - October 20, 2021 Category: Opthalmology Source Type: research
Proinflammatory Cytokine Profile Differences between Primary Open-Angle and Pseudoexfoliative Glaucoma
Conclusion: We conclude that both POAG and PXG show elevated concentrations of proinflammatory cytokines in tear and aqueous humor that could be used as biomarkers for these types of glaucoma and that the concentrations in aqueous humor of three cytokines, IL-12, IL-13, and monocyte chemoattractant protein-1 (monocyte chemotactic and activating factor), could be used to differentiate POAG and PXG. (Source: Ophthalmic Research)
Source: Ophthalmic Research - October 18, 2021 Category: Opthalmology Source Type: research
Proinflammatory cytokine profile differences between primary open angle and pseudoexfoliative glaucoma
(Source: Ophthalmic Research)
Source: Ophthalmic Research - October 18, 2021 Category: Opthalmology Source Type: research
Retina Vascular Structures Near the Optic Disc and in the Macula in Primary Angle Closure Suspects
(Source: Ophthalmic Research)
Source: Ophthalmic Research - October 14, 2021 Category: Opthalmology Source Type: research
Methodical bias, incorrect use of the RADNER Reading Charts and - avoiding misleading reporting in Visual Acuity Measurements Kortuem C, Marx T, Altpeter E, Trauzettel-Klosinski S, Kuester-Gruber S. Comparing reading speeds for reading standardized single sentences and paragraphs in patients with maculopathy. Ophthalmic Res. 2021;64(3):512-522.
(Source: Ophthalmic Research)
Source: Ophthalmic Research - October 6, 2021 Category: Opthalmology Source Type: research
Metabolic Long-Term Monitoring of Transcorneal Electrical Stimulation in Retinitis Pigmentosa
Conclusion: Our long-term observations indicate that TES therapy in RP might lead to a slight increment in oxygen consumption of the retina. However, a larger cohort and longer duration may be needed to adequately power a follow-up study and to confirm this trend reflecting a possible benefit of TES for RP. (Source: Ophthalmic Research)
Source: Ophthalmic Research - October 4, 2021 Category: Opthalmology Source Type: research
Metabolic long-term monitoring of transcorneal electrical stimulation in retinitis pigmentosa.
(Source: Ophthalmic Research)
Source: Ophthalmic Research - October 4, 2021 Category: Opthalmology Source Type: research
Trends of Corneal Transplantation in Adults from 2010 to 2019 in East China: A 10-Year Experience
Conclusions: Over the past decade, infectious keratitis and endothelial dysfunction/bullous keratopathy have been the leading indications for keratoplasty in adults. Preferred surgical techniques for keratoplasty have been shifting from PKP to more customized lamellar keratoplasties. (Source: Ophthalmic Research)
Source: Ophthalmic Research - September 29, 2021 Category: Opthalmology Source Type: research
Trends of Corneal Transplantation in Adults from 2010 to 2019 in East China ：A 10-year Experience
(Source: Ophthalmic Research)
Source: Ophthalmic Research - September 29, 2021 Category: Opthalmology Source Type: research
Comparison of Efficacy and Safety between Conbercept and Ranibizumab in Neovascular Age-Related Macular Degeneration: A Meta-Analysis of Randomized Controlled Trials
Conclusion: Conbercept was similar to ranibizumab in terms of efficacy and safety for the treatment of nAMD in China. Further studies with longer term observation are needed to support this conclusion. (Source: Ophthalmic Research)
Source: Ophthalmic Research - September 28, 2021 Category: Opthalmology Source Type: research
Comparsion of efficacy and safety between conbercept and ranbizumab in neovascular age-related macular degeneration: a meta-analysis of randomized controlled trials
(Source: Ophthalmic Research)
Source: Ophthalmic Research - September 28, 2021 Category: Opthalmology Source Type: research
MicroRNA-425-5p is involved in the development of diabetic retinopathy and regulates the proliferation and migration of retinal microvascular endothelial cells
(Source: Ophthalmic Research)
Source: Ophthalmic Research - September 27, 2021 Category: Opthalmology Source Type: research
