Issue Information
Molecular Oral Microbiology, Volume 35, Issue 1, Page i-iii, January 2020. (Source: Molecular Oral Microbiology)
Source: Molecular Oral Microbiology - January 12, 2020 Category: Microbiology Tags: ISSUE INFORMATION Source Type: research

Epigallocatechin gallate inhibits leukotoxin release by Aggregatibacter actinomycetemcomitans by promoting association with the bacterial membrane
AbstractThe oral pathogen,Aggregatibacter actinomycetemcomitans, produces a number of virulence factors, including a leukotoxin (LtxA), which specifically kills human white blood cells, to provide a colonization advantage to the bacterium. Strains ofA. actinomycetemcomitans that produce more LtxA have been more closely linked to disease, indicating that this toxin plays a key role in pathogenesis of the bacterium. Disruption of the activity of LtxA thus represents a promising approach to reducing the pathogenicity of the bacterium. Catechins are polyphenolic molecules derived from plants, which have shown potent antibacter...
Source: Molecular Oral Microbiology - December 8, 2019 Category: Microbiology Authors: En Hyung Chang, Peter Giaquinto, Joanne Huang, Nataliya V. Balashova, Angela C. Brown Tags: ORIGINAL ARTICLE Source Type: research

Periodontal pathogens and clinical parameters in chronic periodontitis
ConclusionIn this specific population, we found that the best model in predicting the mean pocket depth was microbial dybiosis using the dysbiosis ratio taxa formula. While further studies are needed to assess the validity of these results on the general population, such a dysbiosis ratio could be used in the future to monitor the subgingival microbiota. (Source: Molecular Oral Microbiology)
Source: Molecular Oral Microbiology - November 28, 2019 Category: Microbiology Authors: Emile Boyer, B énédicte Martin, Sandrine Le Gall‐David, Shao Bing Fong, Yves Deugnier, Martine Bonnaure‐Mallet, Vincent Meuric Tags: ORIGINAL ARTICLE Source Type: research

Porphyromonas gingivalis genes conferring fitness in a tobacco ‐rich environment
This study identifies, for the first time, a subset ofP. gingivalis genes required for surviving the plethora of insults present in cigarette smoke. Such conditionally essential genes may delineate bacterial persistence strategies and represent novel therapeutic foci for the prevention ofP. gingivalis infection and related diseases in smokers and in general. (Source: Molecular Oral Microbiology)
Source: Molecular Oral Microbiology - November 18, 2019 Category: Microbiology Authors: Justin A. Hutcherson, Himabindu Gogenini, Gwyneth J. Lamont, Daniel P. Miller, Zuzanna Nowakowska, Anna M. Lasica, Chengcheng Liu, Jan Potempa, Richard J. Lamont, Deborah Yoder ‐Himes, David A. Scott Tags: ORIGINAL ARTICLE Source Type: research

Issue Information
Molecular Oral Microbiology, Volume 34, Issue 6, Page i-iii, December 2019. (Source: Molecular Oral Microbiology)
Source: Molecular Oral Microbiology - November 11, 2019 Category: Microbiology Tags: ISSUE INFORMATION Source Type: research

Characterization and immunostimulatory activity of extracellular vesicles from Filifactor alocis
In this study, we purified and characterized the protein profiles of EVs fromF. alocis and investigated their immunostimulatory activity on human monocytic THP ‐1 and human oral keratinocyte HOK‐16B cell lines. Highly pure EVs were obtained fromF. alocis using density gradient ultracentrifugation. Nanoparticle tracking analysis and transmission electron microscopy showed thatF. alocis EVs were between 50 nm and 270 nm in diameter. Proteome analysis identified 28 proteins, including lipoproteins, autolysins,F. alocis complement inhibitor (FACIN), transporter ‐related proteins, metabolism‐related proteins, and riboso...
Source: Molecular Oral Microbiology - October 31, 2019 Category: Microbiology Authors: Hyun Young Kim, Younggap Lim, Sun ‐Jin An, Bong‐Kyu Choi Tags: ORIGINAL ARTICLE Source Type: research

Tribute: Edward ‘Ned’ Lally
Molecular Oral Microbiology, EarlyView. (Source: Molecular Oral Microbiology)
Source: Molecular Oral Microbiology - October 20, 2019 Category: Microbiology Authors: Bruce J. Shenker, Kathleen Boesze ‐Battaglia, Caroline A. Genco, Ann Progulske‐Fox Tags: Tribute Source Type: research

Streptococcal peptides that signal Enterococcus faecalis cells carrying the pheromone ‐responsive conjugative plasmid pAM373
AbstractPheromone ‐mediated conjugative transfer of enterococcal plasmids can contribute to the dissemination of genes involved in antibiotic resistance, fitness, and virulence among co‐residents of mixed microbial communities. We have previously shown that intergeneric signaling by theStreptococcus gordonii strain Challis heptapeptide s.g.cAM373 (SVFILAA) induces an aggregation ‐substance‐mediated mating response and facilitates plasmid transfer fromEnterococcus faecalis cells carrying the pheromone ‐responsive plasmid pAM373 to both pheromone producing and non‐pheromone producing oral streptococcal recipients...
Source: Molecular Oral Microbiology - October 13, 2019 Category: Microbiology Authors: M. Margaret Vickerman, Jillian M. Mansfield Tags: ORIGINAL ARTICLE Source Type: research

Type I Interferon and Interferon ‐stimulated Gene Expression in Oral Epithelial Cells
AbstractOral epithelial cells (OEC) represent the first site of host interaction with viruses that infect the body through the oral route, however their innate antiviral defense mechanisms have yet to be defined. Previous studies have determined that OEC express pathogen ‐, damage‐ or danger‐associated molecular patterns (PAMPs, or DAMPs), but their expression of key antiviral innate immune mediators, including type I interferons (type I IFN) and interferon‐stimulated genes (ISGs) has not been studied extensively. We used the oral keratinocyte cell line, OKF 6/TERT1 in the presence and absence of the viral mimics p...
Source: Molecular Oral Microbiology - September 12, 2019 Category: Microbiology Authors: David C. Brice, Erika Figgins, Fahong Yu, Gill Diamond Tags: ORIGINAL ARTICLE Source Type: research

Issue Information
Molecular Oral Microbiology, Volume 34, Issue 5, Page i-iv, October 2019. (Source: Molecular Oral Microbiology)
Source: Molecular Oral Microbiology - September 11, 2019 Category: Microbiology Tags: ISSUE INFORMATION Source Type: research

Type IX secretion system is pivotal for expression of gingipain ‐associated virulence of Porphyromonas gingivalis
This article is protected by copyright. All rights reserved. (Source: Molecular Oral Microbiology)
Source: Molecular Oral Microbiology - August 19, 2019 Category: Microbiology Authors: Malgorzata Benedyk, Agata Marczyk, Barbara Chru ścicka Tags: Original Article Source Type: research

Peptide and non ‐peptide mimetics as potential therapeutics targeting oral bacteria and oral biofilms
This article is protected by copyright. All rights reserved. (Source: Molecular Oral Microbiology)
Source: Molecular Oral Microbiology - August 6, 2019 Category: Microbiology Authors: Maryta N. Sztukowska, Mohammad Roky, Donald R. Demuth Tags: Invited Review Source Type: research

Sortase A ‐mediated modification of the Streptococcus mutans transcriptome and virulence traits
This article is protected by copyright. All rights reserved. (Source: Molecular Oral Microbiology)
Source: Molecular Oral Microbiology - July 24, 2019 Category: Microbiology Authors: Xuan Chen, Yuanli He, Haixia Liu, Ying Song, Kaixin Xiong, Xian Peng, Chengcheng Liu, Ling Zou Tags: Original Article Source Type: research

Regulation of IL ‐24 in human oral keratinocytes stimulated with Tannerella forsythia
This article is protected by copyright. All rights reserved. (Source: Molecular Oral Microbiology)
Source: Molecular Oral Microbiology - July 21, 2019 Category: Microbiology Authors: Yeon ‐Kyeong Ko, Sun‐Jin An, Na‐Young Han, Hookeun Lee, Bong‐Kyu Choi Tags: Original Article Source Type: research

Issue Information
Molecular Oral Microbiology, Volume 34, Issue 4, Page i-iv, August 2019. (Source: Molecular Oral Microbiology)
Source: Molecular Oral Microbiology - July 10, 2019 Category: Microbiology Tags: ISSUE INFORMATION Source Type: research