Transcriptional analysis of the mfa ‐cluster genes in Porphyromonas gingivalis strains with one and two mfa5 genes
This study examined the transcriptional unit and activity ofmfa-cluster genes in strains with one (the ATCC 33277 and TDC60 strains) and two (the HG66 and A7436 strains)mfa5 genes. Complementary DNA was prepared from the total RNA extracted from the bacterial cells in the logarithmic growth phase using a random primer. PCR analysis for the intergenic regions frommfa1 tomfa5 ormfa5-2 showed thatmfa1 tomfa5 ormfa5-2 formed a polycistronic gene cluster. Quantitative real-time PCR showed that themfa1 transcription was 5 –10 times higher than that ofmfa2 in all the strains. However,mfa2 tomfa5 mostly showed a comparable expre...
Source: Molecular Oral Microbiology - November 5, 2022 Category: Microbiology Authors: Mari Fujita, Chen ‐Hsuan Chiu, Keiji Nagano Tags: ORIGINAL ARTICLE Source Type: research

Characterization of Leuconostoc mesenteroides MJM60376 as an oral probiotic and its anti ‐biofilm activity
This article is protected by copyright. All rights reserved (Source: Molecular Oral Microbiology)
Source: Molecular Oral Microbiology - October 29, 2022 Category: Microbiology Authors: Mingkun Gu, Huong Thi Nguyen, Joo ‐Hyung Cho, Joo‐Won Suh, Jinhua Cheng Tags: ORIGINAL ARTICLE Source Type: research

Electrochemical Sensors for Oral Biofilm ‐Biomaterials Interface Characterization: a review
This article is protected by copyright. All rights reserved (Source: Molecular Oral Microbiology)
Source: Molecular Oral Microbiology - October 28, 2022 Category: Microbiology Authors: Dipankar Koley Tags: INVITED REVIEW Source Type: research

Streptococcus mutans dexA affects exopolysaccharides production and biofilm homeostasis
Conclusion: In conclusion, deletion ofS. mutans dexA gene re-modules biofilm structure and microbiota composition, thereby leading to decreased cariogenicity. Thus, theS. mutans dexA may be an important target for regulating the cariogenicity of dental plaque biofilms, expecting to be a probiotic for caries control.This article is protected by copyright. All rights reserved (Source: Molecular Oral Microbiology)
Source: Molecular Oral Microbiology - October 22, 2022 Category: Microbiology Authors: Yang Yan, He Hailun, Yang Fenghui, Liu Pingting, Lei Lei, Zhao Zhili, Hu Tao Tags: ORIGINAL ARTICLE Source Type: research

Antagonistic interactions by a high H2O2 ‐producing commensal streptococcus modulate caries development by Streptococcus mutans
AbstractDental caries (tooth-decay) is caused by biofilms harboring polymicrobial communities on teeth that leads to the onset of localized areas of enamel demineralization.Streptococcus mutans has been clinically associated with severe caries in childhood. Although commensal bacteria can combatS. mutans using self-generated antimicrobials such as hydrogen peroxide (H2O2), constant sugar-rich diet consumption disrupts microbial homeostasis shifting toward cariogenic community. Recently,Streptococcus oralis subsp.tigurinus strain J22, an oral isolate, was identified as a uniquely potent H2O2 producer. Here, we assess whethe...
Source: Molecular Oral Microbiology - October 12, 2022 Category: Microbiology Authors: Dongyeop Kim, Tatsuro Ito, Anderson Hara, Yong Li, Jens Kreth, Hyun Koo Tags: ORIGINAL ARTICLE Source Type: research

Oral biofilm dysbiosis during experimental periodontitis
ConclusionThe data supports that murine gingival inflammation and alveolar bone loss develop in response to microbiome shifts. Bacterial diversity increased during progression to bone loss. These findings further support the utilization of the periodontitis ligature model for microbial shift analysis under different experimental conditions.This article is protected by copyright. All rights reserved (Source: Molecular Oral Microbiology)
Source: Molecular Oral Microbiology - October 5, 2022 Category: Microbiology Authors: Apoena Aguiar Ribeiro, Yizu Jiao, Mustafa Girnary, Tomaz Alves, Liang Chen, Anna Farrell, Di Wu, Flavia Teles, Naohiro Inohara, Karen V. Swanson, Julie T. Marchesan Tags: ORIGINAL ARTICLE Source Type: research

Cover Image, Volume 37, Issue 5
The cover image is based on the Original ArticleA reappraisal of microbiome dysbiosis during experimental periodontitis by Marion Arce et al.,https://doi.org/10.1111/omi.12382. (Source: Molecular Oral Microbiology)
Source: Molecular Oral Microbiology - September 28, 2022 Category: Microbiology Authors: Marion Arce, Natalia Endo, Nicolas Dutzan, Loreto Abusleme Tags: ADDITIONAL COVER Source Type: research

Cover Image, Volume 37, Issue 5
Cover Image © Irene Dige. Reproduced with permission. (Source: Molecular Oral Microbiology)
Source: Molecular Oral Microbiology - September 28, 2022 Category: Microbiology Tags: FEATURED COVER Source Type: research

Issue Information
(Source: Molecular Oral Microbiology)
Source: Molecular Oral Microbiology - September 28, 2022 Category: Microbiology Tags: ISSUE INFORMATION Source Type: research

The functional oral microbiome: Biofilm environment, polymicrobial interactions, and community dynamics
(Source: Molecular Oral Microbiology)
Source: Molecular Oral Microbiology - September 28, 2022 Category: Microbiology Authors: Jens Kreth, Hyun Koo, Patricia I. Diaz Tags: EDITORIAL Source Type: research

Antagonistic interactions by a high H2O2 ‐producing commensal streptococci modulate caries development by Streptococcus mutans
This article is protected by copyright. All rights reserved (Source: Molecular Oral Microbiology)
Source: Molecular Oral Microbiology - September 26, 2022 Category: Microbiology Authors: Dongyeop Kim, Tatsuro Ito, Anderson Hara, Yong Li, Jens Kreth, Hyun Koo Tags: ORIGINAL ARTICLE Source Type: research

Transition Metals and Enterococcus faecalis: Homeostasis, Virulence and Perspectives
This article is protected by copyright. All rights reserved (Source: Molecular Oral Microbiology)
Source: Molecular Oral Microbiology - September 21, 2022 Category: Microbiology Authors: Islam A. A. Ali, Gary S.P. Cheung, Prasanna Neelakantan Tags: INVITED REVIEW Source Type: research

Molecular and regulatory mechanisms of oxidative stress adaptation in Streptococcus mutans
This article is protected by copyright. All rights reserved (Source: Molecular Oral Microbiology)
Source: Molecular Oral Microbiology - September 11, 2022 Category: Microbiology Authors: Shuxing Yu, Qizhao Ma, Yuqing Li, Jing Zou Tags: REVIEW ARTICLE Source Type: research

Differential oral microbiome in nonhuman primates from periodontitis ‐susceptible and periodontitis‐resistant matrilines
AbstractRhesus monkeys (n = 36) exhibiting a healthy periodontium at baseline were used to induce progressing periodontitis through ligature placement around premolar/molar teeth. Bacterial samples were collected at baseline, 0.5, 1, and 3 months of disease and at 5 months for disease resolution. The animals were distribu ted into two groups (18/group): 3–7 years (young) and 12–23 years (adult) and stratified based upon matriline susceptibility to periodontitis (PDS, susceptible; PDR, resistant). A total of 444 operational taxonomic units (OTUs) with 100 microbes representing a core microbiome present in ≥75% o f t...
Source: Molecular Oral Microbiology - September 11, 2022 Category: Microbiology Authors: Jeffrey L. Ebersole, Sreenatha Kirakodu, Octovio Gonzalez Tags: ORIGINAL ARTICLE Source Type: research

Glycerol strengthens probiotic effect of Limosilactobacillus reuteri in oral biofilms: a synergistic synbiotic approach
This article is protected by copyright. All rights reserved (Source: Molecular Oral Microbiology)
Source: Molecular Oral Microbiology - September 9, 2022 Category: Microbiology Authors: Wannes Van Holm, Tim Verspecht, Rita Carvalho, Kristel Bernaerts, Nico Boon, Naiera Zayed, Wim Teughels Tags: ORIGINAL ARTICLE Source Type: research