miR ‐27a‐5p alleviates periodontal inflammation by targeting phosphatase and tensin homolog deleted on chromosome ten
ConclusionsmiR-27a-5p alleviated the inflammatory response in periodontitis by targeting PTEN. (Source: Molecular Oral Microbiology)
Source: Molecular Oral Microbiology - May 23, 2023 Category: Microbiology Authors: Li Deng,
Peng ‐cheng Huo,
Mei‐ting Feng,
Rui‐ling Wang,
Rui Jing,
Li‐jun Luo Tags: ORIGINAL ARTICLE Source Type: research
GroEL of Porphyromonas gingivalis ‐induced microRNAs accelerate tumor neovascularization by downregulating thrombomodulin expression in endothelial progenitor cells
In conclusion, the intracellular domain of the TM of EPCs plays a negative regulatory role in the proangiogenic capabilities of EPCs, mainly through direct interaction between TM and PI3K/Akt to inhibit the activation of signaling pathways. The effects of GroEL on tumor growth can be reduced by inhibiting the proangiogenic properties of EPCs through the inhibition of the expression of specific miRNAs. (Source: Molecular Oral Microbiology)
Source: Molecular Oral Microbiology - May 16, 2023 Category: Microbiology Authors: Feng ‐Yen Lin,
Yi‐Ting Tsai,
Chun‐Yao Huang,
Ze‐Hao Lai,
Chien‐Sung Tsai,
Chun‐Ming Shih,
Cheng‐Yen Lin,
Yi‐Wen Lin Tags: ORIGINAL ARTICLE Source Type: research
Issue Information
(Source: Molecular Oral Microbiology)
Source: Molecular Oral Microbiology - May 10, 2023 Category: Microbiology Tags: ISSUE INFORMATION Source Type: research
The involvement of CdhR in Porphyromonas gingivalis during nitric oxide stress
AbstractPorphyromonas gingivalis, the causative agent of adult periodontitis, must gain resistance to frequent oxidative and nitric oxide (NO) stress attacks from immune cells in the periodontal pocket to survive. Previously, we found that, in the wild-type and under NO stress, the expression ofPG1237 (CdhR), the gene encoding for a putative LuxR transcriptional regulator previously called community development and hemin regulator (CdhR), was upregulated 7.7-fold, and its adjacent genePG1236 11.9-fold. Isogenic mutantsP. gingivalis FLL457 ( ΔCdhR::ermF), FLL458 ( ΔPG1236::ermF), and FLL459 ( ΔPG1236-CdhR::ermF) were mad...
Source: Molecular Oral Microbiology - May 4, 2023 Category: Microbiology Authors: Marie ‐Claire Boutrin,
Arunima Mishra,
Charles Wang,
Yuetan Dou,
Hansel M. Fletcher Tags: ORIGINAL ARTICLE Source Type: research
Small noncoding RNA in Streptococci: From regulatory functions to drug development
AbstractStreptococci are a genus of gram-positive coccus of spherical bacteria, including many commensal bacteria and opportunistic pathogens that threaten the public health system. Small noncoding RNAs (sRNAs) are a class of noncoding RNAs regulating gene expression via various regulatory mechanisms, which have been illustrated to play vital roles in regulations of virulence factor expressions. Recent advances in sequencing technology and bioinformatic analysis facilitated discovery of a myriad of sRNAs from pathogenic bacteria, revealing a variety of unique features that contribute to gene expressions and virulence regul...
Source: Molecular Oral Microbiology - April 5, 2023 Category: Microbiology Authors: Yang Yang,
Liu Wang,
Liu Liu,
Jian Zou,
Dingming Huang,
Yuqing Li Tags: REVIEW ARTICLE Source Type: research
Human papillomavirus and Epstein ‐Barr virus co‐infection in oral and oropharyngeal squamous cell carcinomas: A systematic review and meta‐analysis
This article is protected by copyright. All rights reserved (Source: Molecular Oral Microbiology)
Source: Molecular Oral Microbiology - April 4, 2023 Category: Microbiology Authors: Rifat Rahman,
Mushfiq H. Shaikh,
Divya Gopinath,
Adi Idris,
Newell W. Johnson Tags: REVIEW ARTICLE Source Type: research
Gingipains are the important virulence factors of Porphyromonas gingivalis downregulating B10 cells
This article is protected by copyright. All rights reserved (Source: Molecular Oral Microbiology)
Source: Molecular Oral Microbiology - April 3, 2023 Category: Microbiology Authors: Hang Zou,
Niu Zhou,
Xiao Cheng,
Yi Qiu,
Wenhong Hou,
Jianbo Sun Tags: ORIGINAL ARTICLE Source Type: research
Small non ‐coding RNA in Streptococci: From regulatory functions to drug development
This article is protected by copyright. All rights reserved (Source: Molecular Oral Microbiology)
Source: Molecular Oral Microbiology - March 24, 2023 Category: Microbiology Authors: Yang Yang,
Liu Wang,
Liu Liu,
Jian Zou,
Dingming Huang,
Yuqing Li Tags: REVIEW ARTICLE Source Type: research
Issue Information
(Source: Molecular Oral Microbiology)
Source: Molecular Oral Microbiology - March 17, 2023 Category: Microbiology Tags: ISSUE INFORMATION Source Type: research
Regulation of adhesin synthesis in aggregatibacter actinomycetemcomitans
This article is protected by copyright. All rights reserved (Source: Molecular Oral Microbiology)
Source: Molecular Oral Microbiology - March 5, 2023 Category: Microbiology Authors: Jake Tristano,
David R. Danforth,
Matthew J. Wargo,
Keith P. Mintz Tags: ORIGINAL ARTICLE Source Type: research
vicR overexpression in Streptococcus mutans causes aggregation and affects interspecies competition
In this study, we found that thevicR-overexpressing strain was more likely to aggregate to form cell clusters, leading to the formation of abnormal biofilm; the overexpression ofvicR increased the length of the chain ofS. mutans. Furthermore, the expression of the mutacins in thevicR overexpression strain was increased under aerobic conditions. Compared with the control strain and the parental strain, thevicR overexpression strain was more competitive againstStreptococcus gordonii. But there was no significant difference againstStreptococcus sanguinis. In clinical strains, the expression level ofvicR was positively correla...
Source: Molecular Oral Microbiology - February 28, 2023 Category: Microbiology Authors: Jiangchuan Yan,
Tao Gong,
Qizhao Ma,
Ting Zheng,
Jiamin Chen,
Jing Li,
Meiling Jing,
Yongwang Lin,
Xiaowan Wang,
Lei Lei,
Shida Wang,
Jumei Zeng,
Yuqing Li Tags: ORIGINAL ARTICLE Source Type: research
Metabolism of periodontal pathobionts: Their regulatory roles in the dysbiotic microbiota
This article is protected by copyright. All rights reserved (Source: Molecular Oral Microbiology)
Source: Molecular Oral Microbiology - February 23, 2023 Category: Microbiology Authors: Jing Ding,
Chuanjiang Zhao,
Li Gao Tags: REVIEW ARTICLE Source Type: research
Efficacy of cetylpyridinium chloride mouthwash against SARS ‐CoV‐2: A systematic review of randomized controlled trials
Conclusion: Mouthwashes containing Cetylpyridinium Chloride are effective against salivary viral load of SARS-CoV-2 in vivo. There is also the possibility that the use of mouthwash containing Cetylpyridinium Chloride in SARS-CoV-2 positive subjects could reduce transmissibility and severity of COVID-19.This article is protected by copyright. All rights reserved (Source: Molecular Oral Microbiology)
Source: Molecular Oral Microbiology - February 21, 2023 Category: Microbiology Authors: D'Amico Filippo,
Moro Matteo,
Saracino Marco,
Marmiere Marilena,
Cilona Maria Bernadette,
Graham Lloyd ‐Jones,
Zangrillo Alberto Tags: REVIEW ARTICLE Source Type: research
vicR Over ‐expression in Streptococcus mutans Causes Aggregation and Affects Interspecies Competition
This article is protected by copyright. All rights reserved (Source: Molecular Oral Microbiology)
Source: Molecular Oral Microbiology - February 13, 2023 Category: Microbiology Authors: Jiangchuan Yan,
Tao Gong,
Qizhao Ma,
Ting Zheng,
Jiamin Chen,
Jing Li,
Meiling Jing,
Yongwang Lin,
Xiaowan Wang,
Lei Lei,
Shida Wang,
Jumei Zeng,
Yuqing Li Tags: ORIGINAL ARTICLE Source Type: research
Issue Information
(Source: Molecular Oral Microbiology)
Source: Molecular Oral Microbiology - February 7, 2023 Category: Microbiology Tags: ISSUE INFORMATION Source Type: research
