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High ‐Fat Diet Alters Acylcarnitine Metabolism of the Retina and Retinal Pigment Epithelium/Choroidal Tissues in Laser‐Induced Choroidal Neovascularization Rat Models
ConclusionsHFD hastens choroidal neovascularization. The study comprehensively documented acylcarnitine profiles in a CNV rat model. Acylcarnitine's odd-even and carbon-chain length properties may guide  future therapeutics. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - July 26, 2023 Category: Food Science Authors: Pinghui Wei, Meiqin He, Ying Wang, Guoge Han Tags: Research Article Source Type: research

Front Cover: Scientific Evidence for the Beneficial Effects of Dietary Blueberries on Gut Health: A Systematic Review
Mol. Nutr. Food Res. 2023,67,202300096DOI:10.1002/mnfr.202300096Dietary blueberries enhance gut health by improving intestinal morphology, reducing gut permeability, suppressing oxidative stress, ameliorating gut inflammation, and modulating the composition and function of gut microbes. However, there are significant knowledge gaps in this field, and further studies are needed to establish the beneficial effects of blueberries on gut health. This is reported by Pon Velayutham Anandh Babu and co-workers in article number2300096. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - July 25, 2023 Category: Food Science Authors: Ceres Mattos Della Lucia, Livya Alves Oliveira, Kelly Aparecida Dias, Stephanie Michelin Santana Pereira, Aline Rosignoli da Concei ção, Pon Velayutham Anandh Babu Tags: Front Cover Source Type: research

Editorial Board: Mol. Nutr. Food Res. 15'23
(Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - July 25, 2023 Category: Food Science Tags: Editorial Board Source Type: research

Lactiplantibacillus plantarum ZJ316 Reduces Helicobacter pylori Adhesion and Inflammation by Inhibiting the Expression of Adhesin and Urease Genes
ConclusionL. plantarum ZJ316 exhibits excellent adhesion inhibition onH. pylori, and may be used as a probiotic candidate in the prevention or adjuvant therapy of gastric disease caused byH. pylori. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - July 24, 2023 Category: Food Science Authors: Shiying Wu, Yang Xu, Ziqi Chen, Yongqiang Chen, Fangtong Wei, Chenlan Xia, Qingqing Zhou, Ping Li, Qing Gu Tags: Research Article Source Type: research

Pterostilbene Enhances Thermogenesis and Mitochondrial Biogenesis by Activating the SIRT1/PGC ‐1α/SIRT3 Pathway to Prevent Western Diet‐Induced Obesity
ConclusionOverall, these findings suggest PSB and PIN as potential candidates for the improvement of obesity and gut microbiota dysbiosis. With its higher stability, PSB exerts a greater effect than PIN by promoting thermogenesis and mitochondrial biogenesis via SIRT1 activation. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - July 24, 2023 Category: Food Science Authors: Yen ‐Chun Koh, Shin‐Jhih Lin, Kai‐Yu Hsu, Kalyanam Nagabhushanam, Chi‐Tang Ho, Min‐Hsiung Pan Tags: Research Article Source Type: research

Pretreatment with Kahweol Attenuates Sepsis ‐Induced Acute Lung Injury via Improving Mitochondrial Homeostasis in a CaMKKII/AMPK‐Dependent Pathway
ConclusionPretreatment with Kahweol attenuates sepsis-induced acute lung injury via improving mitochondrial homeostasis in a CaMKKII/AMPK-dependent pathway and may be a potential candidate to prevent sepsis-induced ALI. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - July 24, 2023 Category: Food Science Authors: Guorui Li, Tinglv Fu, Wei Wang, Rui Xiong, Bohao Liu, Ruyuan He, Chenzhen Xu, Wenjie Wang, Ning Li, Qing Geng Tags: Research Article Source Type: research

Co ‐occurrence of Mycotoxin‐Induced Hepatotoxicity in Mice Inhibited by Lycopene: Mitochondrial Impairment and Early Hepatic Fibrosis
ConclusionLYC successfully attenuates early hepatic fibrosis mainly through antioxidant activities and prevented mitochondrial injury. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - July 24, 2023 Category: Food Science Authors: Jia Lin, Tianzeng Liang, Yang Huang, Cuige Zuo, Dan Wang, Yulan Liu Tags: Research Article Source Type: research

Front Cover: Cyclic Nigerosylnigerose Attenuates High ‐Fat Diet‐Induced Fat Deposition, Colonic Inflammation, and Abnormal Glucose Metabolism and Modifies Gut Immunoglobulin a Reactivity to Commensal Bacteria
Mol. Nutr. Food Res. 2023,67,202200389DOI:10.1002/mnfr.202200389Oral administration of cyclic nigerosylnigerose (CNN), a dietary fiber, ameliorates abnormal glucose metabolism, fat deposition, and colonic inflammation in mice with high-fat diet-induced obesity. Impressively, the CNN-induced effects are accompanied by an alteration of gut immunoglobulin A (IgA) reactivity to commensal gut bacteria. This is reported by Takeshi Tsuruta and co-workers in article number2200389. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - July 21, 2023 Category: Food Science Authors: Takeshi Tsuruta, Kei Sonoyama, Taisei Miyamoto, Qui D. Nguyen, Akiko Mizote, Mao Teraoka, Naoki Nishino Tags: Front Cover Source Type: research

Editorial Board: Mol. Nutr. Food Res. 14'23
(Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - July 21, 2023 Category: Food Science Tags: Editorial Board Source Type: research

Lacticaseibacillus paracasei K71 Alleviates UVB ‐Induced Skin Barrier Dysfunction by Attenuating Inflammation via Increased IL‐10 Production in Mice
ConclusionThese results indicate that K71 may alleviate UVB-induced skin barrier dysfunction by attenuating inflammation via increasing IL-10 production and that K71 RNAs may induce IL-10 production in macrophages. Therefore, K71 may be beneficial for preventing skin barrier dysfunction. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - July 20, 2023 Category: Food Science Authors: Shigeru Katayama, Rio Yamazaki, Hikaru Umise, Hsu Pei Han, Toshihiro Mihara, Kimiko Uchiyama, Hajime Takahashi, Soichiro Nakamura Tags: Research Article Source Type: research

The Effect of Free and Protein ‐Bound Maillard Reaction Products N‐ε‐Carboxymethyllysine, N‐ε‐Fructosyllysine, and Pyrraline on Nrf2 and NFκB in HCT 116 Cells
ConclusionStudies on the biological effects of glycated proteins require an individual consideration of defined structures. General statements on the effect of “AGEs” in biological systems are scientifically unsound. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - July 19, 2023 Category: Food Science Authors: Jana Raupbach, Stephan K. M üller, Vanessa Schnell, Suse Friedrich, Anne Hellwig, Tilman Grune, Thomas Henle Tags: Research Article Source Type: research

Remodeling of Gut Microbiota by Probiotics Alleviated Heat Stroke ‐Induced Necroptosis in Male Germ Cells
ConclusionProbiotics-based remodeling of gut microbiota (GM) reduces the proliferation of abnormal bacteria and decreases the spread of gut-derived inflammatory mediators into the blood circulation under long-term systemic heat stress, which relieves inflammation on germ cells. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - July 17, 2023 Category: Food Science Authors: Hui Cai, Dezhe Qin, Yundie Liu, Xinrui Guo, Yang Liu, Baohua Ma, Jinlian Hua, Sha Peng Tags: Research Article Source Type: research

Sesamol Mitigates Chronic Iron Overload ‐Induced Cognitive Impairment and Systemic Inflammation via IL‐6 and DMT1 Regulation
ConclusionThese findings suggest that sesamol may be effective in mitigating neuroinflammatory responses and cognitive impairments induced by iron overload, potentially through its involvement in mediating the liver-brain axis. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - July 15, 2023 Category: Food Science Authors: Yajie Wang, Yuyu Zhang, Xinyu Wang, Qingyuan Li, Yu Zhao, Yishan Jiang, Rui Guo, Xuebo Liu, Tian Yuan, Zhigang Liu Tags: Research Article Source Type: research

The Bioactive Dietary Polyphenol Preparation Alleviates Depression and Anxiety ‐Like Behaviors by Modulating the Regional Heterogeneity of Microglia Morphology
ConclusionThe findings suggest regional heterogeneity in microglial responses following chronic stress in subregions of the corticolimbic circuit. Specifically, activation of the immune-inflammatory HMGB1-RAGE pathway may provide a new avenue for preventing the manifestation of psychiatric impairments including stress-induced anxiety- and depression-like behavior, using bioactive and bioavailable polyphenols. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - July 14, 2023 Category: Food Science Authors: Eun ‐Jeong Yang, Tal Frolinger, Umar Haris Iqbal, James Murrough, Giulio M. Pasinetti Tags: Research Article Source Type: research

Dietary Eicosapentaenoic Acid Containing Phosphoethanolamine Plasmalogens Remodels the Lipidome of White Adipose Tissue and Suppresses High ‐Fat Diet Induced Obesity in Mice
ConclusionsEPA-PlsEtn supplementation is demonstrated to remodel lipidome and regulate the fatty acid metabolic process in WAT, indicating it may serve as a new strategy for obesity treatment in the future. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - July 13, 2023 Category: Food Science Authors: Lin Ding, Jinyue Yang, Haoran Guo, Peixu Cong, Jie Xu, Changhu Xue, Xiangzhao Mao, Tiantian Zhang, Yuming Wang Tags: Research Article Source Type: research