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Inhibition of Photoaging by Anthocyanin Metabolites Derived from Rose Petal Extract
ConclusionAnthocyanins in RPE are metabolized to PCA in the body and circulated through the bloodstream to exhibit anti-aging effects on the skin. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - February 7, 2024 Category: Food Science Authors: Woo ‐Jin Sim, Eunjung Lee, Gakyung Lee, Wonchul Lim, Tae‐Gyu Lim Tags: Research Article Source Type: research

α‐Ketoglutarate Improves Ovarian Reserve Function in Primary Ovarian Insufficiency by Inhibiting NLRP3‐Mediated Pyroptosis of Granulosa Cells
ConclusionAKG ameliorates CTX-induced POI by inhibiting NLRP3-mediated pyroptosis, which provides a new therapeutic strategy and drug target for clinical POI patients. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - February 6, 2024 Category: Food Science Authors: Ke Liu, Yafei Wu, Tianlong Li, Zhongxu Wang, Shu Xiao, Zhenghua Peng, Meng Li, Wenhao Xiong, Meixiang Li, Xi Chen, Shun Zhang, Xiaocan Lei Tags: Research Article Source Type: research

A lupin protein hydrolysate protects the central nervous system from oxidative stress in WD ‐fed ApoE−/− mice
A Lupinus angustifolius protein hydrolysate (LPH), containing 101 sequences with antioxidant activity, improves the antioxidant status in vitro and in the brain of mice after 12 weeks of treatment. Specifically, LPH decreases the inducible nitric oxide synthase (iNOS) gene expression, nitric oxide (NO) and 8-hydroxy-2 ’-deoxyguanosine (8-OHdG) production, and increases catalase (CAT) and glutathione reductase (GR) activities and glutathione (GSH) levels. AbstractOxidative stress plays a crucial role in neurodegenerative diseases like Parkinson's and Alzheimer's. Studies indicate the relationship between oxidative stress ...
Source: Molecular Nutrition and Food Research - February 4, 2024 Category: Food Science Authors: Guillermo Santos ‐Sánchez, Eduardo Ponce‐España, Ana Isabel Álvarez‐López, Justo Pedroche, María del Carmen Millán‐Linares, María‐Soledad Fernández‐Pachón, Patricia Judith Lardone, Ivan Cruz‐Chamorro, Antonio Carrillo‐Vico Tags: Research Article Source Type: research

Partial Replacement of NaCl with KCl in Cooked Meat Could Reduce the Liver Damage Through Renin –Angiotensin System in Mice
ConclusionPartial substitution of NaCl with KCl in cooked meat can be a feasible approach for improving the health benefits and developing novel functional meat products for nutritional health interventions. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - February 3, 2024 Category: Food Science Authors: Lifang Zou, Xia Yu, Jiahao Xiong, Conggui Chen, Guiran Xiao Tags: Research Article Source Type: research

Associations of Lifestyle Patterns with Glucose and Lipid Metabolism in Finnish Adults at Increased Risk of Type 2 Diabetes
ConclusionsOur results show, in large scale primary care setting, that healthy eating is associated with better glucose and lipid metabolism and reveal novel associations of lifestyle patterns with metabolites related to glucose metabolism. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - February 3, 2024 Category: Food Science Authors: Suvi Manninen, Tanja Tilles ‐Tirkkonen, Kirsikka Aittola, Reija Männikkö, Leila Karhunen, Marjukka Kolehmainen, Ursula Schwab, Jaana Lindström, Timo Lakka, Jussi Pihlajamäki, the Stop Diabetes study group Tags: Research Article Source Type: research

Exploring Impact of Probiotic ‐Fermented Soymilk on Dextran‐Sulfate‐Sodium‐Induced Ulcerative Colitis via Modulating Inflammation and Gut Microbiota Profile
ConclusionFSM4 attenuates intestinal inflammation and modulates the SCFA-producing bacteria growth, which enable the PPAR- γ activation to alleviate the UC target, which could be a dietary intervention strategy for gut health. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - February 2, 2024 Category: Food Science Authors: Philippe Madjirebaye, Fei Peng, Abdul Mueed, Tao Huang, Bechir Mahamat, Majeste Mbiada Pahane, Qinghua Xi, Xianxiang Chen, Kalli Moussa, Zoua Tessou Kadebe, Brahim Boy Otchom, Yazhou Xu, Mingyong Xie, Tao Xiong, Zhen Peng Tags: Research Article Source Type: research

Protective Effect of Vitexin Against IL ‐17‐Induced Vascular Endothelial Inflammation Through Keap1/Nrf2‐Dependent Signaling Pathway
ConclusionThe findings provide a reliable cell model of vascular low-grade inflammation and indicate Nrf2 protein as the potential target of vitexin to inhibit vascular inflammation. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - February 1, 2024 Category: Food Science Authors: Ting Gan, Qian Xing, Nan Li, Zeyuan Deng, Changxuan Pan, Xiaoru Liu, Liufeng Zheng Tags: Research Article Source Type: research

Changes in Plasma, Urine, and Fecal Metabolome after 16  Weeks of Consuming Dairy With Different Food Matrixes – A Randomized Controlled Trial
ConclusionsOur metabolomics analyses indicate that consumption of heat-treated yogurt and acidified milk exerted similar effects on the metabolic activity in the gut as yogurt consumption. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - February 1, 2024 Category: Food Science Authors: Banny S. B. Correia, Karoline Sandby, Thure Krarup, Faidon Magkos, Nina R. W. Geiker, Hanne Christine Bertram Tags: Research Article Source Type: research

Front Cover: Multi ‐Omics Analysis Reveals Sphingomyelin Accumulation, Glycerolipids Loss, and Disorders of Lipid Metabolism Regulated by Leucine Deprivation in the Liver of Mice
Mol. Nutr. Food Res. 2024,68,2300567DOI:10.1002/mnfr.202300567The cover image is based on the Research ArticleMulti-Omics Analysis Reveals Sphingomyelin Accumulation, Glycerolipids Loss, and Disorders of Lipid Metabolism Regulated by Leucine Deprivation in the Liver of Mice by Haonan Yu et al.,https://doi.org/10.1002/mnfr.202300567 (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - January 31, 2024 Category: Food Science Authors: Haonan Yu, Yaorong Niu, Xinyu Lei, Chunlin Xie, Xianghua Yan Tags: Front Cover Source Type: research

Editorial Board: Mol. Nutr. Food Res. 2'24
(Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - January 31, 2024 Category: Food Science Tags: Editorial Board Source Type: research

Evaluation of the amelioration effect of Ganoderma formosanum extract on delaying PM2.5 damage to lung macrophages
ConclusionsThe study suggests that the WA has the potential to alleviate the PM -induced damage in alveolar macrophages, demonstrating its anti-inflammatory properties. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - January 29, 2024 Category: Food Science Authors: Chih ‐Yao Hou, Chen‐Che Hsieh, Yin‐Ci Hung, Cheng‐Chih Hsu, Chang‐Wei Hsieh, Shu‐Han Yu, Kuan‐Chen Cheng Tags: Research Article Source Type: research

Two Prenylated Chalcones, 4 ‐Hydroxyderricin, and Xanthoangelol Prevent Postprandial Hyperglycemia by Promoting GLUT4 Translocation via the LKB1/AMPK Signaling Pathway in Skeletal Muscle Cells
ConclusionIn conclusion, LKB1/AMPK pathway and subsequent GLUT4 translocation in skeletal muscle cells are involved in Ashitaba chalcone-suppressed acute hyperglycemia. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - January 25, 2024 Category: Food Science Authors: Kevin Odongo, Ayane Abe, Rina Kawasaki, Kyuichi Kawabata, Hitoshi Ashida Tags: Research Article Source Type: research

Gut Microbiota Plays Essential Roles in Soyasaponin's Preventive Bioactivities against Steatohepatitis in the Methionine and Choline Deficient (MCD) Diet ‐Induced Non‐Alcoholic Steatohepatitis (NASH) Mice
ConclusionGM plays essential roles in soyasaponin's preventive bioactivities against steatohepatitis in MCD diet-induced NASH mice. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - January 18, 2024 Category: Food Science Authors: Chuhong Su, Jiexian Wang, Huiyu Luo, Junbin Chen, Fengjuan Lin, Jiaqi Mo, Fei Xiong, Longying Zha Tags: Research Article Source Type: research

Urine and Dried Blood Spots From Children and Pregnant Women Reveal Phytochemicals, Amino Acids, and Carnitine Metabolites as Cowpea Consumption Biomarkers
ConclusionThis feeding study for cowpea biomarkers supports the utility of a suite of key metabolites classified as amino acids, lipids, and phytochemicals for dietary legume and cowpea-specific food exposures of global health importance. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - January 18, 2024 Category: Food Science Authors: Madison Tipton, Bridget A. Baxter, Brigitte A. Pfluger, Brooke Sayre ‐Chavez, María Muñoz‐Amatriaín, Corey D. Broeckling, Issah Shani, Matilda Steiner‐Asiedu, Mark Manary, Elizabeth P. Ryan Tags: Research Article Source Type: research

Profiles of Intestinal Flora in Breastfed Obese Children and Selecting Functional Strains Against Obesity
ConclusionsL. plantarum H-72 is screened out for its potential antiobesity effect, which presents a potential and promising avenue for future interventions aimed at preventing pediatric obesity in breastfed children. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - January 17, 2024 Category: Food Science Authors: Cong Liang, Hai ‐Yue Niu, Lin‐Zheng Lyu, Yi‐Fan Wu, Lan‐Wei Zhang Tags: Research Article Source Type: research