Scientific Evidence for the Beneficial Effects of Dietary Blueberries on Gut Health: A Systematic Review
Dietary blueberries enhance gut health by improving intestinal morphology, reducing gut permeability, suppressing oxidative stress, ameliorating gut inflammation, and modulating the composition and function of gut microbes. However, there are significant knowledge gaps in this field, and further studies are needed to establish the beneficial effects of blueberries on gut health. AbstractEmerging evidence indicates the association between an unhealthy gut and chronic diseases. A healthy gut comprises an intact gut epithelium and balanced gut microbes. Diet is one of the critical factors that modulate gut health by positivel...
Source: Molecular Nutrition and Food Research - July 11, 2023 Category: Food Science Authors: Ceres Mattos Della Lucia, Livya Alves Oliveira, Kelly Aparecida Dias, Stephanie Michelin Santana Pereira, Aline Rosignoli da Concei ção, Pon Velayutham Anandh Babu Tags: Review Source Type: research

Photoperiod ‐Dependent Effects of Grape‐Seed Proanthocyanidins on Adipose Tissue Metabolic Markers in Healthy Rats
ConclusionsThe results indicate that GSPE modulates the expression of important metabolic markers of WAT and BAT in a photoperiod-dependent manner. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - July 10, 2023 Category: Food Science Authors: Èlia Navarro‐Masip, Francesca Manocchio, Romina M. Rodríguez, Francisca Isabel Bravo, Cristina Torres‐Fuentes, Begoña Muguerza, Gerard Aragonès Tags: Research Article Source Type: research

Extension Region Domain of Soybean 7S Globulin Contributes to Serum Triglyceride ‐Lowering Effect via Modulation of Bile Acids Homeostasis
ConclusionOral administration of ER peptides can effectively lower serum TG level by regulating BAs metabolism. ER peptides have potential to be used as a candidate pharmaceutical for the intervention of dyslipidemia. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - July 10, 2023 Category: Food Science Authors: Kaining Han, Guangxin Feng, Tanghao Li, Zhili Wan, Wenjing Zhao, Xiaoquan Yang Tags: Research Article Source Type: research

5 ‐(3′,4′‐Dihydroxyphenyl)‐γ‐Valerolactone Is a Substrate for Human Paraoxonase: A Novel Pathway in Flavan‐3‐ol Metabolism
ConclusionPONs are involved in flavan-3-ol metabolic pathway in humans. PON polymorphisms have a minor contribution to inter-individual differences in the levels of γVL metabolites, without affecting their use as a nutritional biomarker. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - July 10, 2023 Category: Food Science Authors: Tony Y. Momma, Gunter G. C. Kuhnle, Reedmond Y. Fong, Jodi L. Ensunsa, Alan Crozier, Hagen Schroeter, Javier I. Ottaviani Tags: Research Article Source Type: research

Vitis vinifera L. Bioactive Components Modulate Adipose Tissue Metabolic Markers of Healthy Rats in a Photoperiod ‐Dependent Manner
ConclusionsThese results clearly show that bioactive compounds of grapes can modulate the metabolic markers of white and brown adipose tissues in a photoperiod and depot-dependent manner, partly affecting EE when consumed out of season. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - July 9, 2023 Category: Food Science Authors: Èlia Navarro‐Masip, Francesca Manocchio, Marina Colom‐Pellicer, Xavier Escoté, Lisard Iglesias‐Carres, Enrique Calvo, Francisca I Bravo, Begoña Muguerza, Yves Desjardins, Gerard Aragonès Tags: Research Article Source Type: research

Butyrate Improves Porcine Endometrial Epithelial Cell Receptivity via Enhancing Acetylation of Histone H3K9
ConclusionThe findings reveal that butyrate improves endometrial epithelial cell receptivity by enhancing the acetylation of histone H3K9, which shows nutritional regulation and therapeutic potential for poor uterine receptivity and difficulty in embryo implantation. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - July 8, 2023 Category: Food Science Authors: Qianhong Ye, Haoyu Li, Baoyang Xu, Ziyi He, Xianghua Yan Tags: Research Article Source Type: research

Front Cover: Anti ‐Inflammatory Effect of Clostridium butyricum‐Derived Extracellular Vesicles in Ulcerative Colitis: Impact on Host microRNAs Expressions and Gut Microbiome Profiles
Mol. Nutr. Food Res. 2023,67,2200884DOI:10.1002/mnfr.202200884Extracellular Vesicles (EVs) secreted from probiotics are potential EV-based nanomaterials therapy in inflammatory bowel disease (IBD).Clostridium butyricum-derived extracellular vesicles could be a novel agent for treating colitis and colonic miR-199a-3p might serve as a potential therapeutic target for IBD. This is reported by Yingping Xiao and co-workers in article number2200884. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - July 4, 2023 Category: Food Science Authors: Lingyan Ma, Wentao Lyu, Yuanyuan Song, Kai Chen, Lu Lv, Hua Yang, Wen Wang, Yingping Xiao Tags: Front Cover Source Type: research

Editorial Board: Mol. Nutr. Food Res. 13'23
(Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - July 4, 2023 Category: Food Science Tags: Editorial Board Source Type: research

The Association between Circulating 25 ‐Hydroxyvitamin D and Carotid Intima‐Media Thickness Is Mediated by Gut Microbiota and Fecal and Serum Metabolites in Adults
ConclusionsThese findings show a beneficial association between plasma 25(OH)D and the CCA-cIMT progression. The identified multi-omics biomarkers provide novel mechanistic insights for the epidemiological association. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - June 29, 2023 Category: Food Science Authors: Chun ‐ying Liu, Bang‐yan Li, Yuhui Liang, Jinjian Xu, Lai‐Bao Zhuo, Jia‐ting Wang, Wei Hu, Ting‐yu Sun, Fengzhe Xu, Wanglong Gou, Ju‐Sheng Zheng, Yu‐ming Chen Tags: Research Article Source Type: research

Fat ‐Diets in Perinatal Stages Altered Nr3c2‐Mediated Ca2+ Currents in Mesenteric Arteries of Offspring Rats
ConclusionThe results firstly demonstrate that aldosterone-receptor activation can stimulate Ca2+ currents via LTCC in vascular myocytes, which can be altered by perinatal foods via epigenetic changes of DNA methylation in the promoters of Nr3c2 and LTCC. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - June 28, 2023 Category: Food Science Authors: Qiutong Zheng, Na Li, Yingying Zhang, Jingyang Li, Eryun Zhang, Zhice Xu Tags: Research Article Source Type: research

Associations of Meat and Fish/Seafood Intake with All ‐Cause and Cause‐Specific Mortality from Three Prospective Cohort Studies in Korea
ConclusionReduction of red and processed meat, and processed fish consumption or replacement of these foods with fish may be beneficial for longevity in Korean adults. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - June 27, 2023 Category: Food Science Authors: Sangwon Chung, Jin ‐Taek Hwang, Hyojee Joung, Sangah Shin Tags: Research Article Source Type: research

Milk Exosomes from Gestational Diabetes Mellitus (GDM) and Healthy Parturient Exhibit Differential miRNAs Profiles and Distinct Regulatory Bioactivity on Hepatocyte Proliferation
ConclusionHM exosomes from GDM and healthy parturient exhibit differential miRNAs profiles and distinct regulatory bioactivity on hepatocyte proliferation. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - June 26, 2023 Category: Food Science Authors: Zhongdaixi Zheng, Jiaqi Mo, Fengjuan Lin, Jiexian Wang, Junbin Chen, Huiyu Luo, Yuguo Liu, Chuhong Su, Xiangfu Gu, Fei Xiong, Longying Zha Tags: Research Article Source Type: research

α‐Lactalbumin Peptide Asp‐Gln‐Trp Ameliorates Hepatic Steatosis and Oxidative Stress in Free Fatty Acids‐Treated HepG2 Cells and High‐Fat Diet‐Induced NAFLD Mice by Activating the PPARα Pathway
ConclusionThose results indicate that α-lactalbumin peptide DQW may be an effective dietary supplement for alleviating NAFLD by alleviating lipid deposition and oxidative stress. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - June 25, 2023 Category: Food Science Authors: Haoran Chen, Yanfeng Ma, Xiaofen Qi, Jianjun Tian, Ying Ma, Tianjiao Niu Tags: Research Article Source Type: research

The Gut Microbiome and Autoimmune Hepatitis: Implications for Early Diagnostic Biomarkers and Novel Therapies
The microbiome-gut-liver axis plays an important role in the occurrence and development of autoimmune hepatitis (AIH). Thus, gut microbiota has great potential to be biomarkers for early diagnosis of AIH. More importantly, probiotics, prebiotics, synbiotics, and fecal microbiota transplantation may be used to correct disorders of this axis. AbstractAutoimmune hepatitis (AIH) is a serious chronic liver disease that may last for decades and eventually develop into cirrhosis and liver failure. In recent years, people have paid more attention to the microbiome-gut-liver axis, which provides guidance for all to explore the role...
Source: Molecular Nutrition and Food Research - June 24, 2023 Category: Food Science Authors: Liping Li, Yongbo Kang Tags: Review Source Type: research

Front Cover: Single ‐Cell Transcriptomics Reveals the Difference of Aortic Atherosclerosis Response to Phytosterols and Oxidation Products of Sterols
Mol. Nutr. Food Res. 2023,67,202200811DOI:10.1002/mnfr.202200811Biological effects of dietary are evaluated for aortic cells after dietary exposure via Single-Cell Transcriptomics. Three pathways of differentiation indicate that dietary regulation affects the differentiation of aortic cells. Aortic cells are cultured by food, and healthy or unhealthy food will cause to different results. This is reported by Yao Xie, Baiyi Lu, and co-workers in article number2200811. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - June 22, 2023 Category: Food Science Authors: Zhangtie Wang, Mengmeng Wang, Yunrui Lu, Yongli Ji, Jesus Simal ‐Gandara, Fan Xiao, Yan Liu, Liangxiao Zhang, Maurizio Battino, Peiwu Li, Jianbo Xiao, Yao Xie, Baiyi Lu Tags: Front Cover Source Type: research