Application of whole-cell biosensors for analysis and improvement of L- and D-lactic acid fermentation by Lactobacillus spp. from the waste of glucose syrup production
Lactic acid is one of the most important organic acids, with various applications in the food, beverage, pharmaceutical, cosmetic, and chemical industries. Optically pure forms of L- and D-lactic acid produced... (Source: Microbial Cell Factories)
Source: Microbial Cell Factories - October 30, 2023 Category: Microbiology Authors: Ernesta Augustiniene, Ilona Jonuskiene, Jurgita Kailiuviene, Edita Mazoniene, Kestutis Baltakys and Naglis Malys Tags: Research Source Type: research
A novel protein purification scheme based on salt inducible self-assembling peptides
Protein purification remains a critical need for biosciences and biotechnology. It frequently requires multiple rounds of chromatographic steps that are expensive and time-consuming. Our lab previously reporte... (Source: Microbial Cell Factories)
Source: Microbial Cell Factories - October 30, 2023 Category: Microbiology Authors: Guang Zeng, Yinzhen Zheng, Ya Xiang, Run Liu, Xiaofeng Yang and Zhanglin Lin Tags: Research Source Type: research
Mechanism of furfural toxicity and metabolic strategies to engineer tolerance in microbial strains
Lignocellulosic biomass represents a carbon neutral cheap and versatile source of carbon which can be converted to biofuels. A pretreatment step is frequently used to make the lignocellulosic carbon bioavailab... (Source: Microbial Cell Factories)
Source: Microbial Cell Factories - October 28, 2023 Category: Microbiology Authors: S. Bilal Jilani and Daniel G. Olson Tags: Review Source Type: research
Systems biology of industrial oxytetracycline production in Streptomyces rimosus: the secrets of a mutagenized hyperproducer
Oxytetracycline which is derived from Streptomyces rimosus, inhibits a wide range of bacteria and is industrially important. The underlying biosynthetic processes are complex and hinder rational engineering, so i... (Source: Microbial Cell Factories)
Source: Microbial Cell Factories - October 28, 2023 Category: Microbiology Authors: Selma Beganovic, Christian R ückert-Reed, Hilda Sucipto, Wei Shu, Lars Gläser, Thomas Patschkowski, Ben Struck, Jörn Kalinowski, Andriy Luzhetskyy and Christoph Wittmann Tags: Research Source Type: research
Adaptive laboratory evolution of Rhodococcus rhodochrous DSM6263 for chlorophenol degradation under hypersaline condition
Normally, a salt amount greater than 3.5% (w/v) is defined as hypersaline. Large amounts of hypersaline wastewater containing organic pollutants need to be treated before it can be discharged into the environm... (Source: Microbial Cell Factories)
Source: Microbial Cell Factories - October 26, 2023 Category: Microbiology Authors: Jie Zheng, Zhengzhi Zhang, Juan An, Yubin Xue and Bo Yu Tags: Research Source Type: research
Systematic engineering pinpoints a versatile strategy for the expression of functional cytochrome P450 enzymes in Escherichia coli cell factories
Production of plant secondary metabolites in engineered microorganisms provides a scalable and sustainable alternative to their sourcing from nature or through chemical synthesis. However, the biosynthesis of ... (Source: Microbial Cell Factories)
Source: Microbial Cell Factories - October 25, 2023 Category: Microbiology Authors: Michal Poborsky, Christoph Crocoll, Mohammed Saddik Motawie and Barbara Ann Halkier Tags: Research Source Type: research
Study on the intracellular adaptative mechanism of Acidithiobacillus caldus MTH-04 to NaCl stress
To understand the adaptive mechanism of bioleaching microorganism Acidithiobacillus caldus MTH-04, its physiology and metabolic changes at the transcriptional level were systemically studied. The results of growt... (Source: Microbial Cell Factories)
Source: Microbial Cell Factories - October 25, 2023 Category: Microbiology Authors: Min Li and Jianping Wen Tags: Research Source Type: research
Identification of a novel family B DNA polymerase from Enterococcus phage IME199 and its overproduction in Escherichia coli BL21(DE3)
Identification and characterization of novel, faithful and processive DNA polymerases is a driving force in the development of DNA amplification methods. Purification of proteins from natural phages is often t... (Source: Microbial Cell Factories)
Source: Microbial Cell Factories - October 21, 2023 Category: Microbiology Authors: Pengjun Han, Huahao Fan and Yigang Tong Tags: Research Source Type: research
Caproate production from Enset fiber in one-pot two-step fermentation using anaerobic fungi (Neocallimastix cameroonii strain G341) and Clostridium kluyveri DSM 555
Lignocellulosic biomass plays a crucial role in creating a circular bioeconomy and minimizing environmental impact. Enset biomass is a byproduct of traditional Ethiopian Enset food processing that is thrown aw... (Source: Microbial Cell Factories)
Source: Microbial Cell Factories - October 20, 2023 Category: Microbiology Authors: Nebyat Seid, Katrin Ochsenreither and Anke Neumann Tags: Research Source Type: research
Optimized methyl donor and reduced precursor degradation pathway for seleno-methylselenocysteine production in Bacillus subtilis
Seleno-methylselenocysteine (SeMCys) is an effective component of selenium supplementation with anti-carcinogenic potential that can ameliorate neuropathology and cognitive deficits. In a previous study, a SeM... (Source: Microbial Cell Factories)
Source: Microbial Cell Factories - October 19, 2023 Category: Microbiology Authors: Xian Yin, Meiyi Zhao, Yu Zhou, Hulin Yang, Yonghong Liao and Fenghuan Wang Tags: Research Source Type: research
Two-step conversion of polyethylene into recombinant proteins using a microbial platform
The increasing prevalence of plastic waste combined with the inefficiencies of mechanical recycling has inspired interest in processes that can convert these waste streams into value-added biomaterials. To dat... (Source: Microbial Cell Factories)
Source: Microbial Cell Factories - October 17, 2023 Category: Microbiology Authors: Alexander Connor, Jessica V. Lamb, Massimiliano Delferro, Mattheos Koffas and R. Helen Zha Tags: Research Source Type: research
Semi-rational engineering an aldo –keto reductase for stereocomplementary reduction of α-keto amide compounds
Enantio-pure α-hydroxy amides are valuable intermediates for the synthesis of chiral pharmaceuticals. The asymmetric reduction of α-keto amides to generate chiral α-hydroxy amides is a difficult and challengin... (Source: Microbial Cell Factories)
Source: Microbial Cell Factories - October 15, 2023 Category: Microbiology Authors: Ruixuan Bai, Baoling Chen and Liangyu Zheng Tags: Research Source Type: research
Correction: Transcriptomic profiling of the yeast Komagataella phaffii in response to environmental alkalinization
(Source: Microbial Cell Factories)
Source: Microbial Cell Factories - October 14, 2023 Category: Microbiology Authors: Marcel Albacar, Abdelghani Zekhnini, Jorge P érez-Valle, José L. Martínez, Antonio Casamayor and Joaquín Ariño Tags: Correction Source Type: research
CRISPR-Cas9 assisted non-homologous end joining genome editing system of Halomonas bluephagenesis for large DNA fragment deletion
Halophiles possess several unique properties and have broad biotechnological applications including industrial biotechnology production. Halomonas spp., especially Halomonas bluephagenesis, have been engineered t... (Source: Microbial Cell Factories)
Source: Microbial Cell Factories - October 14, 2023 Category: Microbiology Authors: Chunyan Liu, Yaxin Yue, Yanfen Xue, Cheng Zhou and Yanhe Ma Tags: Research Source Type: research
Heterologous overproduction of oviedomycin by refactoring biosynthetic gene cluster and metabolic engineering of host strain Streptomyces coelicolor
Oviedomycin is one among several polyketides known for their potential as anticancer agents. The biosynthetic gene cluster (BGC) for oviedomycin is primarily found in Streptomyces antibioticus. However, because t... (Source: Microbial Cell Factories)
Source: Microbial Cell Factories - October 14, 2023 Category: Microbiology Authors: Boncheol Gu, Duck Gyun Kim, Do-Kyung Kim, Minji Kim, Hyun Uk Kim and Min-Kyu Oh Tags: Research Source Type: research
