Potential use of proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibition and prevention method in viral infection
Cellular lipid membranes serve as the primary barrier preventing viral infection of the host cell and provide viruses with a critical initial point of contact. Occasionally, viruses can utilize lipids as viral... (Source: Microbial Cell Factories)
Source: Microbial Cell Factories - March 25, 2024 Category: Microbiology Authors: Khursheed Muzammil, Mohammad Hosseini Hooshiar, Shirin Varmazyar, Thabit Moath Omar, Manal Morad Karim, Sadeq Aadi, Shaylan Kalavi and Saman Yasamineh Tags: Review Source Type: research
Temporal dynamics of stress response in Halomonas elongata to NaCl shock: physiological, metabolomic, and transcriptomic insights
The halophilic bacterium Halomonas elongata is an industrially important strain for ectoine production, with high value and intense research focus. While existing studies primarily delve into the adaptive mechani... (Source: Microbial Cell Factories)
Source: Microbial Cell Factories - March 23, 2024 Category: Microbiology Authors: Junxiong Yu, Yue Zhang, Hao Liu, Yuxuan Liu, Ali Mohsin, Zebo Liu, Yanning Zheng, Jianmin Xing, Jing Han, Yingping Zhuang, Meijin Guo and Zejian Wang Tags: Research Source Type: research
Mutagenetic analysis of the biosynthetic pathway of tetramate bripiodionen bearing 3-(2H-pyran-2-ylidene)pyrrolidine-2,4-dione skeleton
Natural tetramates are a family of hybrid polyketides bearing tetramic acid (pyrrolidine-2,4-dione) moiety exhibiting a broad range of bioactivities. Biosynthesis of tetramates in microorganisms is normally di... (Source: Microbial Cell Factories)
Source: Microbial Cell Factories - March 21, 2024 Category: Microbiology Authors: Haixia Zang, Yijia Cheng, Mengjia Li, Lin Zhou, Li-Li Hong, Hai Deng, Hou-Wen Lin and Yongjun Zhou Tags: Research Source Type: research
Modifications of the 5 ’ region of the CASPONTM tag’s mRNA further enhance soluble recombinant protein production in Escherichia coli
Escherichia coli is one of the most commonly used host organisms for the production of biopharmaceuticals, as it allows for cost-efficient and fast recombinant protein expression. However, challenging proteins ar... (Source: Microbial Cell Factories)
Source: Microbial Cell Factories - March 20, 2024 Category: Microbiology Authors: Christoph K öppl, Wolfgang Buchinger, Gerald Striedner and Monika Cserjan-Puschmann Tags: Research Source Type: research
Engineering Saccharomyces cerevisiae for targeted hydrolysis and fermentation of glucuronoxylan through CRISPR/Cas9 genome editing
The abundance of glucuronoxylan (GX) in agricultural and forestry residual side streams positions it as a promising feedstock for microbial conversion into valuable compounds. By engineering strains of the wid... (Source: Microbial Cell Factories)
Source: Microbial Cell Factories - March 16, 2024 Category: Microbiology Authors: Jonas L. Ravn, Jo ão H.C. Manfrão-Netto, Jana B. Schaubeder, Luca Torello Pianale, Stefan Spirk, Iván F. Ciklic and Cecilia Geijer Tags: Research Source Type: research
Development of hybrid biomicroparticles: cellulose exposing functionalized fusion proteins
One of the leading current trends in technology is the miniaturization of devices to the microscale and nanoscale. The highly advanced approaches are based on biological systems, subjected to bioengineering us... (Source: Microbial Cell Factories)
Source: Microbial Cell Factories - March 14, 2024 Category: Microbiology Authors: Joanna Żebrowska, Piotr Mucha, Maciej Prusinowski, Daria Krefft, Agnieszka Żylicz-Stachula, Milena Deptuła, Aneta Skoniecka, Agata Tymińska, Małgorzata Zawrzykraj, Jacek Zieliński, Michał Pikuła and Piotr M. Skowron Tags: Research Source Type: research
The strain-dependent cytostatic activity of Lactococcus lactis on CRC cell lines is mediated through the release of arginine deiminase
Colorectal cancer (CRC) is one of the most commonly diagnosed cancers, posing a serious public health challenge that necessitates the development of new therapeutics, therapies, and prevention methods. Among t... (Source: Microbial Cell Factories)
Source: Microbial Cell Factories - March 14, 2024 Category: Microbiology Authors: Rafa ł Jastrząb, Rafał Tomecki, Aneta Jurkiewicz, Damian Graczyk, Agnieszka K. Szczepankowska, Jennifer Mytych, Damian Wolman and Pawel Siedlecki Tags: Research Source Type: research
RuBisCO activity assays: a simplified biochemical redox approach for in vitro quantification and an RNA sensor approach for in vivo monitoring
Ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO) is the most abundant soluble protein in nature. Extensive studies have been conducted for improving its activity in photosynthesis through approaches l... (Source: Microbial Cell Factories)
Source: Microbial Cell Factories - March 14, 2024 Category: Microbiology Authors: Muhammad Faisal, Aditya P. Sarnaik, Nandini Kannoju, Nima Hajinajaf, Muhammad Javaid Asad, Ryan W. Davis and Arul M. Varman Tags: Methodology Source Type: research
Production, characterization and biomedical potential of biosurfactants produced by haloalkaliphilic archaea from Wadi El-Natrun, Egypt
This study delves into the fascinating field of halophilic archaea an... (Source: Microbial Cell Factories)
Source: Microbial Cell Factories - March 14, 2024 Category: Microbiology Authors: Basma T. Alghamrawy, Ghada E. Hegazy, Soraya A. Sabry and Hanan Ghozlan Tags: Research Source Type: research
Unveiling the silver lining: examining the effects of biogenic silver nanoparticles on the growth dynamics of in vitro olive shoots
The current study aimed to evaluate the effects of biogenic silver nanoparticles (AgNPs) on growth behavior and leaf anatomy of in vitro growing shoots of ‘Picual’ and ‘Dolce’ olive cultivars. Biosynthesis of ... (Source: Microbial Cell Factories)
Source: Microbial Cell Factories - March 13, 2024 Category: Microbiology Authors: Mohamed S. Hasanin, Sayed A.M. Hassan, A. M. AbdAllatif and Osama M. Darwesh Tags: Research Source Type: research
Transcriptome analysis reveals multiple targets of erythritol-related transcription factor EUF1 in unconventional yeast Yarrowia Lipolytica
Erythritol is a four-carbon polyol with an unclear role in metabolism of some unconventional yeasts. Its production has been linked to the osmotic stress response, but the mechanism of stress protection remain... (Source: Microbial Cell Factories)
Source: Microbial Cell Factories - March 12, 2024 Category: Microbiology Authors: DA. Rzechonek, M. Szczepa ńczyk, I. Borodina, C. Neuvéglise and AM. Mirończuk Tags: Research Source Type: research
Effective synthesis of high-content fructooligosaccharides in engineered Aspergillus niger
Aspergillus niger ATCC 20611 is an industrially important fructooligosaccharides (FOS) producer since it produces the β-fructofuranosidase with superior transglycosylation activity, which is responsible for the c... (Source: Microbial Cell Factories)
Source: Microbial Cell Factories - March 9, 2024 Category: Microbiology Authors: Xiufen Wan, Lu Wang, Jingjing Chang, Jing Zhang, Zhiyun Zhang, Kewen Li, Guilian Sun, Caixia Liu and Yaohua Zhong Tags: Research Source Type: research
Correction: Stable expression of HIV-1 MPER extended epitope on the surface of the recombinant probiotic bacteria Escherichia Coli Nissle 1917 using CRISPR/Cas9
(Source: Microbial Cell Factories)
Source: Microbial Cell Factories - March 6, 2024 Category: Microbiology Authors: Nathaniel Ninyio, Katharina Schmitt, Gladys Sergon, Charlotta Nilsson, S ören Andersson and Nikolai Scherbak Tags: Correction Source Type: research
Automated workflow for characterization of bacteriocin production in natural producers Lactococcus lactis and Latilactobacillus sakei
Lactic acid bacteria are commonly used as protective starter cultures in food products. Among their beneficial effects is the production of ribosomally synthesized peptides termed bacteriocins that kill or inh... (Source: Microbial Cell Factories)
Source: Microbial Cell Factories - March 3, 2024 Category: Microbiology Authors: Valentin Steier, Lisa Prigolovkin, Alexander Reiter, Tobias Neddermann, Wolfgang Wiechert, Sebastian J. Reich, Christian U. Riedel and Marco Oldiges Tags: Methodology Source Type: research
Enhancement of cellulolytic enzyme production from intrageneric protoplast fusion of Aspergillus species and evaluating the hydrolysate scavenging activity
Lignocellulosic biomass provides a great starting point for the production of energy, chemicals, and fuels. The major component of lignocellulosic biomass is cellulose, the employment of highly effective enzym... (Source: Microbial Cell Factories)
Source: Microbial Cell Factories - March 2, 2024 Category: Microbiology Authors: Doaa A. Goda, Huda M. Shakam, Mai E. Metwally, Hager A. Abdelrasoul and Mohamed M. Yacout Tags: Research Source Type: research
