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Combined endophthalmitis and orbital cellulitis in patients with corona virus disease (COVID-19)
ConclusionCombined endophthalmitis and orbital cellulitis can be one of the early presentations of patients with COVID-19 infection with poor visual prognosis.Trial registrationClinical registration: clinicaltrials.gov identifier:NCT04456556. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - September 15, 2021 Category: Opthalmology Source Type: research

Fungal keratitis after small incision lenticule extraction (SMILE): a case report and review of the literature
ConclusionsInfectious keratitis after SMILE is unusual. To our knowledge, this is the first report of perforated fungal keratitis post-SMILE. PKP eradicated the infection. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - September 3, 2021 Category: Opthalmology Source Type: research

Histopathological, immunohistochemical and molecular biologic study of an enucleated specimen of a case of Eales ’ disease
We present a 29-year-old male, diagnosed with Eales’ disease in both eyes with persistent intraocular inflammation. Enucleation of the pthisical right eye was subjected for histopathological examination immunohistochemistry and molecular biologic study for mycobacterial tuberculosis DNA. Our study showed that Eales disease is probably a T cell mediated disease which is triggered by mycobacterial TB DNA. Further studies are nee ded to confirm our findings. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - September 1, 2021 Category: Opthalmology Source Type: research

Rituximab for treatment of non-infectious and non-malignant orbital inflammatory disease
ConclusionsOverall, RTX appears to be both efficacious and well-tolerated as second- or third-line therapy for patients with non-infectious/non-malignant orbital inflammation. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - August 27, 2021 Category: Opthalmology Source Type: research

Rituximab for non-infectious Uveitis and Scleritis
ConclusionsOverall, RTX appeared to be both effective and well-tolerated as second or third-line therapy for patients with non-infectious uveitis and scleritis. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - August 16, 2021 Category: Opthalmology Source Type: research

Risk factors and outcomes of post-traumatic endophthalmitis: a retrospective single-center study
ConclusionHigh proportions of post-traumatic endophthalmitis patients had subsequent poor visual outcomes. Therefore, safety and protective measurements, especially when performing activities related to high-velocity objects, and the institution of prophylactic antibiotics in high-risk groups should be promptly considered to reduce the incidence. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - August 2, 2021 Category: Opthalmology Source Type: research

Effective diagnosis by real-time PCR of herpes simplex diffuse endotheliitis that is similar in appearance to fungal keratitis: case series
ConclusionsReal-time PCR was an effective tool in diagnosing HSV diffuse endotheliitis with feathery infiltration. Topical corticosteroids in conjunction with oral and topical antivirals were an effective treatment. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - July 12, 2021 Category: Opthalmology Source Type: research

Reactivation of Vogt-Koyanagi-Harada disease under control for more than 6  years, following anti-SARS-CoV-2 vaccination
ConclusionVKH disease results from an autoimmune process directed against melanocyte associated antigens which can be controlled when early and sustained immunosuppressive treatment is introduced. It seems that anti-SARS-CoV-2 vaccination can be at the origin of reactivation of long-time controlled disease. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - July 5, 2021 Category: Opthalmology Source Type: research

The acute phase response protein SERPINA3 is increased in tear fluid from the unaffected eyes of patients with unilateral acute anterior uveitis
ConclusionsThe acute phase response protein SERPINA3 was increased in tear samples of unaffected eyes of patients with unilateral AAU compared with healthy controls. This study highlights SERPINA3 as a potential biomarker for AAU. Future research should explore the dynamic properties of SERPINA3 in the tear fluid of active and quiescent uveitis eyes. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - July 2, 2021 Category: Opthalmology Source Type: research

Foveal reorganization after treatment of acute foveal toxoplasmic retinochoroiditis
ConclusionIn foveal toxoplasmic retinochoroiditis lesions, timely treatment is associated with retinal reorganization and visual improvement. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - June 21, 2021 Category: Opthalmology Source Type: research

Factors associated with the development of ocular candidiasis and ocular prognosis with echinocandin therapy for candidemia
ConclusionOne-seventh of patients with candidemia developed probable OC. Given the evidence of female andC. albicans as the factors associated with OC development, careful ophthalmologic management is required with these factors, especially in candidemia. Although echinocandins had no correlation with OC development and did not lead to the deterioration of ocular prognosis, further investigation is required. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - June 14, 2021 Category: Opthalmology Source Type: research

Post-traumatic exogenous endophthalmitis caused by Nocardia farcinica
AbstractA case report of post-traumatic exogenous endophthalmitis caused byNocardia farcinica, including treatment procedures, microbiology examination, and systemic medications. A 23-year-old male suffered a penetrating corneal injury that was treated with sutures. On the thirteenth day after the final suture was removed, an anterior uveitis developed and progressed to whitish, plump, nodular, and tufted exudates within the anterior chamber over the next 10  days; this led to an indication for intraocular surgery. Anterior chamber lavage and resection of solid fibrinous exudates (using a vitrectomy knife) for a complete...
Source: Journal of Ophthalmic Inflammation and Infection - June 1, 2021 Category: Opthalmology Source Type: research

“Environmental risk factors associated with juvenile idiopathic arthritis associated uveitis: a systematic review of the literature”
ConclusionsThis review identifies a potential role for allergy and vitamin D in JIA-U. It also illustrates the paucity of data regarding environmental risk factors for JIA-U and highlights the need for further research to both identify additional risk factors and replicate existing findings. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - May 24, 2021 Category: Opthalmology Source Type: research

“Old wine in a new bottle” - post COVID-19 infection, central serous chorioretinopathy and the steroids
ConclusionCSCR can occur post COVID-19 due to steroid administration and physicians administering it should be aware of this and refer the patients to an ophthalmologist earlier. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - May 14, 2021 Category: Opthalmology Source Type: research

Varicella zoster virus anterior uveitis complicated by thalamic stroke
We report a case of varicella zoster virus (VZV)-associated anterior uveitis in a patient with weight loss, arthritis and signs of inflammatory bowel disease. Her clinical course included the development of a thalamic stroke secondary to VZV cerebral vasculopathy. Following antiviral therapy, the patient ’s neurologic symptoms recovered and her ophthalmic findings improved. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - May 1, 2021 Category: Opthalmology Source Type: research