Histopathological, immunohistochemical and molecular biologic study of an enucleated specimen of a case of Eales ’ disease

We present a 29-year-old male, diagnosed with Eales’ disease in both eyes with persistent intraocular inflammation. Enucleation of the pthisical right eye was subjected for histopathological examination immunohistochemistry and molecular biologic study for mycobacterial tuberculosis DNA. Our study showed that Eales disease is probably a T cell mediated disease which is triggered by mycobacterial TB DNA. Further studies are nee ded to confirm our findings.
Source: Journal of Ophthalmic Inflammation and Infection - Category: Opthalmology Source Type: research