Integration of genome-wide association studies reveal loci associated with salt tolerance score of rice at the seedling stage
J Appl Genet. 2023 Aug 9. doi: 10.1007/s13353-023-00775-7. Online ahead of print.ABSTRACTSalt threatens rice cultivation in many countries. Hence, breeding new varieties with high salt tolerance is important.A panel of 2,391 rice accessions from the 3 K Rice Genome Project was selected to evaluate salt tolerance via the standard evaluation score (SES) in hydroponics under 60 mM NaCl at the seedling stage. Three sub-population panels including 1,332, 628, and 386 accessions from the original 2,391 ones were constructed based on low relatedness revealed by a phylogenetic tree generated by Archaeopteryx Tree. A genome-wide as...
Source: J Appl Genet - August 9, 2023 Category: Genetics & Stem Cells Authors: Nhung Thi Hong Phan Cuong Van Pham Hanh Thi Tang Loc Van Nguyen Long Viet Nguyen Pierre Bertin Source Type: research
Integration of genome-wide association studies reveal loci associated with salt tolerance score of rice at the seedling stage
J Appl Genet. 2023 Aug 9. doi: 10.1007/s13353-023-00775-7. Online ahead of print.ABSTRACTSalt threatens rice cultivation in many countries. Hence, breeding new varieties with high salt tolerance is important.A panel of 2,391 rice accessions from the 3 K Rice Genome Project was selected to evaluate salt tolerance via the standard evaluation score (SES) in hydroponics under 60 mM NaCl at the seedling stage. Three sub-population panels including 1,332, 628, and 386 accessions from the original 2,391 ones were constructed based on low relatedness revealed by a phylogenetic tree generated by Archaeopteryx Tree. A genome-wide as...
Source: J Appl Genet - August 9, 2023 Category: Genetics & Stem Cells Authors: Nhung Thi Hong Phan Cuong Van Pham Hanh Thi Tang Loc Van Nguyen Long Viet Nguyen Pierre Bertin Source Type: research
Integration of genome-wide association studies reveal loci associated with salt tolerance score of rice at the seedling stage
J Appl Genet. 2023 Aug 9. doi: 10.1007/s13353-023-00775-7. Online ahead of print.ABSTRACTSalt threatens rice cultivation in many countries. Hence, breeding new varieties with high salt tolerance is important.A panel of 2,391 rice accessions from the 3 K Rice Genome Project was selected to evaluate salt tolerance via the standard evaluation score (SES) in hydroponics under 60 mM NaCl at the seedling stage. Three sub-population panels including 1,332, 628, and 386 accessions from the original 2,391 ones were constructed based on low relatedness revealed by a phylogenetic tree generated by Archaeopteryx Tree. A genome-wide as...
Source: J Appl Genet - August 9, 2023 Category: Genetics & Stem Cells Authors: Nhung Thi Hong Phan Cuong Van Pham Hanh Thi Tang Loc Van Nguyen Long Viet Nguyen Pierre Bertin Source Type: research
Integration of genome-wide association studies reveal loci associated with salt tolerance score of rice at the seedling stage
J Appl Genet. 2023 Aug 9. doi: 10.1007/s13353-023-00775-7. Online ahead of print.ABSTRACTSalt threatens rice cultivation in many countries. Hence, breeding new varieties with high salt tolerance is important.A panel of 2,391 rice accessions from the 3 K Rice Genome Project was selected to evaluate salt tolerance via the standard evaluation score (SES) in hydroponics under 60 mM NaCl at the seedling stage. Three sub-population panels including 1,332, 628, and 386 accessions from the original 2,391 ones were constructed based on low relatedness revealed by a phylogenetic tree generated by Archaeopteryx Tree. A genome-wide as...
Source: J Appl Genet - August 9, 2023 Category: Genetics & Stem Cells Authors: Nhung Thi Hong Phan Cuong Van Pham Hanh Thi Tang Loc Van Nguyen Long Viet Nguyen Pierre Bertin Source Type: research
A-to-I RNA editing shows dramatic up-regulation in osteosarcoma and broadly regulates tumor-related genes by altering microRNA target regions
J Appl Genet. 2023 Aug 5. doi: 10.1007/s13353-023-00777-5. Online ahead of print.ABSTRACTA-to-I RNA editing is a prevalent type of RNA modification in animals. The dysregulation of RNA editing has led to multiple human cancers. However, the role of RNA editing has never been studied in osteosarcoma, a complex bone cancer with unknown molecular basis. We retrieved the RNA-sequencing data from 24 primary osteosarcoma patients and 3 healthy controls. We systematically profiled the RNA editomes in these samples and quantitatively identified reliable differential editing sites (DES) between osteosarcoma and normal samples. RNA ...
Source: J Appl Genet - August 5, 2023 Category: Genetics & Stem Cells Authors: Fuqun Ge Xinyue Cao Yankai Jiang Source Type: research
A-to-I RNA editing shows dramatic up-regulation in osteosarcoma and broadly regulates tumor-related genes by altering microRNA target regions
J Appl Genet. 2023 Aug 5. doi: 10.1007/s13353-023-00777-5. Online ahead of print.ABSTRACTA-to-I RNA editing is a prevalent type of RNA modification in animals. The dysregulation of RNA editing has led to multiple human cancers. However, the role of RNA editing has never been studied in osteosarcoma, a complex bone cancer with unknown molecular basis. We retrieved the RNA-sequencing data from 24 primary osteosarcoma patients and 3 healthy controls. We systematically profiled the RNA editomes in these samples and quantitatively identified reliable differential editing sites (DES) between osteosarcoma and normal samples. RNA ...
Source: J Appl Genet - August 5, 2023 Category: Genetics & Stem Cells Authors: Fuqun Ge Xinyue Cao Yankai Jiang Source Type: research
A-to-I RNA editing shows dramatic up-regulation in osteosarcoma and broadly regulates tumor-related genes by altering microRNA target regions
J Appl Genet. 2023 Aug 5. doi: 10.1007/s13353-023-00777-5. Online ahead of print.ABSTRACTA-to-I RNA editing is a prevalent type of RNA modification in animals. The dysregulation of RNA editing has led to multiple human cancers. However, the role of RNA editing has never been studied in osteosarcoma, a complex bone cancer with unknown molecular basis. We retrieved the RNA-sequencing data from 24 primary osteosarcoma patients and 3 healthy controls. We systematically profiled the RNA editomes in these samples and quantitatively identified reliable differential editing sites (DES) between osteosarcoma and normal samples. RNA ...
Source: J Appl Genet - August 5, 2023 Category: Genetics & Stem Cells Authors: Fuqun Ge Xinyue Cao Yankai Jiang Source Type: research
Circular RNA circ_0000119 promotes cervical cancer cell growth and migration via miR-433-3p/PAK2 axis
J Appl Genet. 2023 Aug 4. doi: 10.1007/s13353-023-00772-w. Online ahead of print.ABSTRACTThe purpose of this study was to investigate the role of circ_0000119 on CC progression and its molecular mechanism. The expression levels of circ_0000119, miR-433-3p, and p21-activated kinase 2 (PAK2) in CC tissues and cell lines were measured by quantitative real-time polymerase chain reaction (qRT-PCR). Cell proliferation was assessed using 3-(4,5)-dimethylthiahiazo (-z-y1)-3,5-di-phenytetrazoliumromide (MTT) assay, 5-Ethynyl-2'-deoxyuridine (EdU) assay and colony formation assay. Cell cycle and apoptosis were assessed by flow cytom...
Source: J Appl Genet - August 4, 2023 Category: Genetics & Stem Cells Authors: Junxiao Zhang Guanghua Chu Lihua Zheng Juandi Liu Juxian He Source Type: research
Circular RNA circ_0000119 promotes cervical cancer cell growth and migration via miR-433-3p/PAK2 axis
J Appl Genet. 2023 Aug 4. doi: 10.1007/s13353-023-00772-w. Online ahead of print.ABSTRACTThe purpose of this study was to investigate the role of circ_0000119 on CC progression and its molecular mechanism. The expression levels of circ_0000119, miR-433-3p, and p21-activated kinase 2 (PAK2) in CC tissues and cell lines were measured by quantitative real-time polymerase chain reaction (qRT-PCR). Cell proliferation was assessed using 3-(4,5)-dimethylthiahiazo (-z-y1)-3,5-di-phenytetrazoliumromide (MTT) assay, 5-Ethynyl-2'-deoxyuridine (EdU) assay and colony formation assay. Cell cycle and apoptosis were assessed by flow cytom...
Source: J Appl Genet - August 4, 2023 Category: Genetics & Stem Cells Authors: Junxiao Zhang Guanghua Chu Lihua Zheng Juandi Liu Juxian He Source Type: research
Circular RNA circ_0000119 promotes cervical cancer cell growth and migration via miR-433-3p/PAK2 axis
J Appl Genet. 2023 Aug 4. doi: 10.1007/s13353-023-00772-w. Online ahead of print.ABSTRACTThe purpose of this study was to investigate the role of circ_0000119 on CC progression and its molecular mechanism. The expression levels of circ_0000119, miR-433-3p, and p21-activated kinase 2 (PAK2) in CC tissues and cell lines were measured by quantitative real-time polymerase chain reaction (qRT-PCR). Cell proliferation was assessed using 3-(4,5)-dimethylthiahiazo (-z-y1)-3,5-di-phenytetrazoliumromide (MTT) assay, 5-Ethynyl-2'-deoxyuridine (EdU) assay and colony formation assay. Cell cycle and apoptosis were assessed by flow cytom...
Source: J Appl Genet - August 4, 2023 Category: Genetics & Stem Cells Authors: Junxiao Zhang Guanghua Chu Lihua Zheng Juandi Liu Juxian He Source Type: research
High molecular risk variants, severe thrombocytopenia and large unstained cells count affect the outcome in primary myelofibrosis
J Appl Genet. 2023 Jul 29. doi: 10.1007/s13353-023-00771-x. Online ahead of print.ABSTRACTApart from the driver mutations, high molecular risk (HMR) variants and other factors have been reported to influence the prognosis of primary myelofibrosis (PMF). The aim of our study was to investigate the impact of laboratory and molecular characteristics at the time of diagnosis (TOD) on the PMF outcome. The study group consisted of 82 patients recruited from three Polish university centers. Among the driver mutations, only CALR type 1 positively influenced the overall survival (OS). The risk of progression to accelerated or blast...
Source: J Appl Genet - July 28, 2023 Category: Genetics & Stem Cells Authors: Zuzanna Kandu ła Micha ł Janowski Barbara Wi ęckowska Edyta Paczkowska Aleksandra Mroczkowska-B ękarciak Marta Sobas Krzysztof Lewandowski Source Type: research
High molecular risk variants, severe thrombocytopenia and large unstained cells count affect the outcome in primary myelofibrosis
J Appl Genet. 2023 Jul 29. doi: 10.1007/s13353-023-00771-x. Online ahead of print.ABSTRACTApart from the driver mutations, high molecular risk (HMR) variants and other factors have been reported to influence the prognosis of primary myelofibrosis (PMF). The aim of our study was to investigate the impact of laboratory and molecular characteristics at the time of diagnosis (TOD) on the PMF outcome. The study group consisted of 82 patients recruited from three Polish university centers. Among the driver mutations, only CALR type 1 positively influenced the overall survival (OS). The risk of progression to accelerated or blast...
Source: J Appl Genet - July 28, 2023 Category: Genetics & Stem Cells Authors: Zuzanna Kandu ła Micha ł Janowski Barbara Wi ęckowska Edyta Paczkowska Aleksandra Mroczkowska-B ękarciak Marta Sobas Krzysztof Lewandowski Source Type: research
High molecular risk variants, severe thrombocytopenia and large unstained cells count affect the outcome in primary myelofibrosis
J Appl Genet. 2023 Jul 29. doi: 10.1007/s13353-023-00771-x. Online ahead of print.ABSTRACTApart from the driver mutations, high molecular risk (HMR) variants and other factors have been reported to influence the prognosis of primary myelofibrosis (PMF). The aim of our study was to investigate the impact of laboratory and molecular characteristics at the time of diagnosis (TOD) on the PMF outcome. The study group consisted of 82 patients recruited from three Polish university centers. Among the driver mutations, only CALR type 1 positively influenced the overall survival (OS). The risk of progression to accelerated or blast...
Source: J Appl Genet - July 28, 2023 Category: Genetics & Stem Cells Authors: Zuzanna Kandu ła Micha ł Janowski Barbara Wi ęckowska Edyta Paczkowska Aleksandra Mroczkowska-B ękarciak Marta Sobas Krzysztof Lewandowski Source Type: research
High molecular risk variants, severe thrombocytopenia and large unstained cells count affect the outcome in primary myelofibrosis
J Appl Genet. 2023 Jul 29. doi: 10.1007/s13353-023-00771-x. Online ahead of print.ABSTRACTApart from the driver mutations, high molecular risk (HMR) variants and other factors have been reported to influence the prognosis of primary myelofibrosis (PMF). The aim of our study was to investigate the impact of laboratory and molecular characteristics at the time of diagnosis (TOD) on the PMF outcome. The study group consisted of 82 patients recruited from three Polish university centers. Among the driver mutations, only CALR type 1 positively influenced the overall survival (OS). The risk of progression to accelerated or blast...
Source: J Appl Genet - July 28, 2023 Category: Genetics & Stem Cells Authors: Zuzanna Kandu ła Micha ł Janowski Barbara Wi ęckowska Edyta Paczkowska Aleksandra Mroczkowska-B ękarciak Marta Sobas Krzysztof Lewandowski Source Type: research
High molecular risk variants, severe thrombocytopenia and large unstained cells count affect the outcome in primary myelofibrosis
J Appl Genet. 2023 Jul 29. doi: 10.1007/s13353-023-00771-x. Online ahead of print.ABSTRACTApart from the driver mutations, high molecular risk (HMR) variants and other factors have been reported to influence the prognosis of primary myelofibrosis (PMF). The aim of our study was to investigate the impact of laboratory and molecular characteristics at the time of diagnosis (TOD) on the PMF outcome. The study group consisted of 82 patients recruited from three Polish university centers. Among the driver mutations, only CALR type 1 positively influenced the overall survival (OS). The risk of progression to accelerated or blast...
Source: J Appl Genet - July 28, 2023 Category: Genetics & Stem Cells Authors: Zuzanna Kandu ła Micha ł Janowski Barbara Wi ęckowska Edyta Paczkowska Aleksandra Mroczkowska-B ękarciak Marta Sobas Krzysztof Lewandowski Source Type: research
