Novel targets and their functions in the prognosis of uterine corpus endometrial cancer patients
J Appl Genet. 2024 Apr 19. doi: 10.1007/s13353-024-00856-1. Online ahead of print.ABSTRACTAberrant mRNA expression is implicated in uterine corpus endometrial carcinoma (UCEC) oncogenesis and progression. However, effective prognostic biomarkers for UCEC remain limited. We aimed to construct a reliable multi-gene risk model using gene expression profiles. Utilizing TCGA data (543 UCEC samples, 35 controls), we identified 1517 differentially acting genes. Weighted gene co-expression complex analysis (WGCCA), hub gene screening, and risk regression analysis (RRA) were employed to determine prognosis-related genes and constru...
Source: J Appl Genet - April 19, 2024 Category: Genetics & Stem Cells Authors: Xin Sui Penghui Feng Jie Guo Xingtong Chen Rong Chen Yanmin Zhang Falin He Feng Deng Source Type: research
HO-CR and HOLL-CR: new forms of winter oilseed rape (Brassica napus L.) with altered fatty acid composition and resistance to selected pathotypes of Plasmodiophora brassicae (clubroot)
In this study, forms with a modified fatty acid composition of seed oil were successfully combined with a source of resistance to Plasmodiophora brassicae Wor., a harmful protist-causing clubroot. Three HO-type recombinants in F6-F12 generations with oleic acid content of 80.2-82.1% and one HOLL-type F6 inbred mutant recombinant (HOmut × LLmut), with a high oleic acid content (80.9%) and reduced linolenic acid content (2.3%), were crossed with the cultivar Tosca, resistant to several pathotypes of P. brassicae. The work involved genotyping with the use of DNA markers specific for allelic variants of desaturase genes respo...
Source: J Appl Genet - April 18, 2024 Category: Genetics & Stem Cells Authors: Stanis ław Spasibionek Katarzyna Miko łajczyk Marcin Matuszczak Joanna Kaczmarek Noor Ramzi Ma łgorzata Jędryczka Source Type: research
Correction to: Novel DNA methylation biomarkers for early diagnosis of oral tongue squamous cell carcinoma (OTSCC)
J Appl Genet. 2024 Apr 12. doi: 10.1007/s13353-024-00858-z. Online ahead of print.NO ABSTRACTPMID:38607498 | DOI:10.1007/s13353-024-00858-z (Source: J Appl Genet)
Source: J Appl Genet - April 12, 2024 Category: Genetics & Stem Cells Authors: Hayat Ali Abdullah Alafaria Areej Saud Jalal Source Type: research
Correction to: The effect of library preparation protocol on the efficiency of heteroplasmy detection in mitochondrial DNA using two massively parallel sequencing Illumina systems
J Appl Genet. 2024 Apr 13. doi: 10.1007/s13353-024-00864-1. Online ahead of print.NO ABSTRACTPMID:38609674 | DOI:10.1007/s13353-024-00864-1 (Source: J Appl Genet)
Source: J Appl Genet - April 12, 2024 Category: Genetics & Stem Cells Authors: Patrycja Daca-Roszak Joanna Fiedorowicz Maciej Jankowski Marzanna Ciesielka Grzegorz Teresi ński Beata Lipska-Zi ętkiewicz Ewa Zi ętkiewicz Tomasz Grzybowski Katarzyna Skonieczna Source Type: research
Correction to: Novel DNA methylation biomarkers for early diagnosis of oral tongue squamous cell carcinoma (OTSCC)
J Appl Genet. 2024 Apr 12. doi: 10.1007/s13353-024-00858-z. Online ahead of print.NO ABSTRACTPMID:38607498 | DOI:10.1007/s13353-024-00858-z (Source: J Appl Genet)
Source: J Appl Genet - April 12, 2024 Category: Genetics & Stem Cells Authors: Hayat Ali Abdullah Alafaria Areej Saud Jalal Source Type: research
Correction to: The effect of library preparation protocol on the efficiency of heteroplasmy detection in mitochondrial DNA using two massively parallel sequencing Illumina systems
J Appl Genet. 2024 Apr 13. doi: 10.1007/s13353-024-00864-1. Online ahead of print.NO ABSTRACTPMID:38609674 | DOI:10.1007/s13353-024-00864-1 (Source: J Appl Genet)
Source: J Appl Genet - April 12, 2024 Category: Genetics & Stem Cells Authors: Patrycja Daca-Roszak Joanna Fiedorowicz Maciej Jankowski Marzanna Ciesielka Grzegorz Teresi ński Beata Lipska-Zi ętkiewicz Ewa Zi ętkiewicz Tomasz Grzybowski Katarzyna Skonieczna Source Type: research
Correction to: Novel DNA methylation biomarkers for early diagnosis of oral tongue squamous cell carcinoma (OTSCC)
J Appl Genet. 2024 Apr 12. doi: 10.1007/s13353-024-00858-z. Online ahead of print.NO ABSTRACTPMID:38607498 | DOI:10.1007/s13353-024-00858-z (Source: J Appl Genet)
Source: J Appl Genet - April 12, 2024 Category: Genetics & Stem Cells Authors: Hayat Ali Abdullah Alafaria Areej Saud Jalal Source Type: research
Correction to: The effect of library preparation protocol on the efficiency of heteroplasmy detection in mitochondrial DNA using two massively parallel sequencing Illumina systems
J Appl Genet. 2024 Apr 13. doi: 10.1007/s13353-024-00864-1. Online ahead of print.NO ABSTRACTPMID:38609674 | DOI:10.1007/s13353-024-00864-1 (Source: J Appl Genet)
Source: J Appl Genet - April 12, 2024 Category: Genetics & Stem Cells Authors: Patrycja Daca-Roszak Joanna Fiedorowicz Maciej Jankowski Marzanna Ciesielka Grzegorz Teresi ński Beata Lipska-Zi ętkiewicz Ewa Zi ętkiewicz Tomasz Grzybowski Katarzyna Skonieczna Source Type: research
Correction to: Novel DNA methylation biomarkers for early diagnosis of oral tongue squamous cell carcinoma (OTSCC)
J Appl Genet. 2024 Apr 12. doi: 10.1007/s13353-024-00858-z. Online ahead of print.NO ABSTRACTPMID:38607498 | DOI:10.1007/s13353-024-00858-z (Source: J Appl Genet)
Source: J Appl Genet - April 12, 2024 Category: Genetics & Stem Cells Authors: Hayat Ali Abdullah Alafaria Areej Saud Jalal Source Type: research
Correction to: The effect of library preparation protocol on the efficiency of heteroplasmy detection in mitochondrial DNA using two massively parallel sequencing Illumina systems
J Appl Genet. 2024 Apr 13. doi: 10.1007/s13353-024-00864-1. Online ahead of print.NO ABSTRACTPMID:38609674 | DOI:10.1007/s13353-024-00864-1 (Source: J Appl Genet)
Source: J Appl Genet - April 12, 2024 Category: Genetics & Stem Cells Authors: Patrycja Daca-Roszak Joanna Fiedorowicz Maciej Jankowski Marzanna Ciesielka Grzegorz Teresi ński Beata Lipska-Zi ętkiewicz Ewa Zi ętkiewicz Tomasz Grzybowski Katarzyna Skonieczna Source Type: research
Correction to: Novel DNA methylation biomarkers for early diagnosis of oral tongue squamous cell carcinoma (OTSCC)
J Appl Genet. 2024 Apr 12. doi: 10.1007/s13353-024-00858-z. Online ahead of print.NO ABSTRACTPMID:38607498 | DOI:10.1007/s13353-024-00858-z (Source: J Appl Genet)
Source: J Appl Genet - April 12, 2024 Category: Genetics & Stem Cells Authors: Hayat Ali Abdullah Alafaria Areej Saud Jalal Source Type: research
Genetic dissection of green pod yield in dolichos bean, an orphan vegetable legume, using new molecular markers
J Appl Genet. 2024 Apr 8. doi: 10.1007/s13353-024-00865-0. Online ahead of print.ABSTRACTIn the era of genomic-assisted breeding for crop improvement, developing new molecular markers and validating them for use in breeding programs are the prelude. Dolichos bean is one of the most important vegetable legume crops owing to its nutrient-rich green pods used as vegetables. Limitations in genomic resources, including molecular markers, restrict the accelerated improvement of the crop. In the present investigation, a set of 430 new simple sequence repeat markers was developed from sequence information of a reference variety. T...
Source: J Appl Genet - April 8, 2024 Category: Genetics & Stem Cells Authors: Vinayak Spoorthi Sampangi Ramesh Nagenahalli Chandrappa Sunitha None Vedashree Panichayil Vijayakumar Vaijayanthi Chandrappa Anilkumar Source Type: research
Genetic dissection of green pod yield in dolichos bean, an orphan vegetable legume, using new molecular markers
J Appl Genet. 2024 Apr 8. doi: 10.1007/s13353-024-00865-0. Online ahead of print.ABSTRACTIn the era of genomic-assisted breeding for crop improvement, developing new molecular markers and validating them for use in breeding programs are the prelude. Dolichos bean is one of the most important vegetable legume crops owing to its nutrient-rich green pods used as vegetables. Limitations in genomic resources, including molecular markers, restrict the accelerated improvement of the crop. In the present investigation, a set of 430 new simple sequence repeat markers was developed from sequence information of a reference variety. T...
Source: J Appl Genet - April 8, 2024 Category: Genetics & Stem Cells Authors: Vinayak Spoorthi Sampangi Ramesh Nagenahalli Chandrappa Sunitha None Vedashree Panichayil Vijayakumar Vaijayanthi Chandrappa Anilkumar Source Type: research
Genetic dissection of green pod yield in dolichos bean, an orphan vegetable legume, using new molecular markers
J Appl Genet. 2024 Apr 8. doi: 10.1007/s13353-024-00865-0. Online ahead of print.ABSTRACTIn the era of genomic-assisted breeding for crop improvement, developing new molecular markers and validating them for use in breeding programs are the prelude. Dolichos bean is one of the most important vegetable legume crops owing to its nutrient-rich green pods used as vegetables. Limitations in genomic resources, including molecular markers, restrict the accelerated improvement of the crop. In the present investigation, a set of 430 new simple sequence repeat markers was developed from sequence information of a reference variety. T...
Source: J Appl Genet - April 8, 2024 Category: Genetics & Stem Cells Authors: Vinayak Spoorthi Sampangi Ramesh Nagenahalli Chandrappa Sunitha None Vedashree Panichayil Vijayakumar Vaijayanthi Chandrappa Anilkumar Source Type: research
Genetic dissection of green pod yield in dolichos bean, an orphan vegetable legume, using new molecular markers
J Appl Genet. 2024 Apr 8. doi: 10.1007/s13353-024-00865-0. Online ahead of print.ABSTRACTIn the era of genomic-assisted breeding for crop improvement, developing new molecular markers and validating them for use in breeding programs are the prelude. Dolichos bean is one of the most important vegetable legume crops owing to its nutrient-rich green pods used as vegetables. Limitations in genomic resources, including molecular markers, restrict the accelerated improvement of the crop. In the present investigation, a set of 430 new simple sequence repeat markers was developed from sequence information of a reference variety. T...
Source: J Appl Genet - April 8, 2024 Category: Genetics & Stem Cells Authors: Vinayak Spoorthi Sampangi Ramesh Nagenahalli Chandrappa Sunitha None Vedashree Panichayil Vijayakumar Vaijayanthi Chandrappa Anilkumar Source Type: research
